iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.70e-17	61.8	197	229

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgv 34
           H+ +v+c++  ++++vsGs+D t kvW l +g 
   Q: 197  HEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGQ 229
           99*******9449**************998875 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MAAAAEDGAA AVEPATRPAA GPALWRLPEE LLLLICSYLD MRALGRLAQV CRWLRRFTSC 60
DLLWRPIARA SLNSGFTRLG TDLMTSIPVK ERVKLSQNWR LGRCRDRILL KWRYSQMPWM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGAAGAAGG GCCGAGACGC TCCGGGAGGC AGGATGAGGG CAGCGCAGAG CCAGGGAAGG 60
AGGAATGTAG GGTTGGGGCC GGGCGGCGGG AGGACCACAG CCTGGAGAGA GCACAAGAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0019005--C:SCF ubiquitin ligase complex
GO:0051216--P:cartilage development
GO:0042733--P:embryonic digit morphogenesis
GO:0002053--P:positive regulation of mesenchymal cell proliferation
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

rno:309444

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002129	Ailuropoda melanoleuca	94.12	0.00e+00	736.00
IUUC-Apl-003837	Anas platyrhynchos	71.43	4.00e-141	493.00
IUUC-Aca-004776	Anolis carolinensis	66.58	1.00e-138	486.00
IUUC-Ame-010651	Astyanax mexicanus	61.18	1.00e-111	395.00
IUUC-Bta-013495	Bos taurus	93.32	0.00e+00	696.00
IUUC-Cja-018901	Callithrix jacchus	94.04	0.00e+00	696.00
IUUC-Cfa-021251	Canis familiaris	92.51	0.00e+00	726.00
IUUC-Cpo-021750	Cavia porcellus	91.38	0.00e+00	631.00
IUUC-Csa-024026	Chlorocebus sabaeus	94.31	0.00e+00	730.00
IUUC-Cho-024496	Choloepus hoffmanni	72.09	1.00e-150	526.00
IUUC-Cin-025142	Ciona intestinalis	30.95	5.00e-26	111.00
IUUC-Csv-025883	Ciona savignyi	35.86	2.00e-65	243.00
IUUC-Dre-027447	Danio rerio	57.81	1.00e-129	456.00
IUUC-Dno-029572	Dasypus novemcinctus	77.84	2.00e-164	572.00
IUUC-Dor-030982	Dipodomys ordii	85.91	0.00e+00	654.00
IUUC-Ete-032917	Echinops telfairi	91.08	0.00e+00	629.00
IUUC-Eca-033969	Equus caballus	93.37	0.00e+00	695.00
IUUC-Eeu-034850	Erinaceus europaeus	82.38	0.00e+00	627.00
IUUC-Fca-036182	Felis catus	88.50	0.00e+00	665.00
IUUC-Fal-037391	Ficedula albicollis	67.73	2.00e-145	508.00
IUUC-Gmo-038632	Gadus morhua	56.66	5.00e-127	447.00
IUUC-Gga-040783	Gallus gallus	71.97	1.00e-157	549.00
IUUC-Gac-042314	Gasterosteus aculeatus	56.59	3.00e-111	395.00
IUUC-Ggo-044739	Gorilla gorilla	93.77	0.00e+00	724.00
IUUC-Hsa-046705	Homo sapiens	93.77	0.00e+00	695.00
IUUC-Itr-048014	Ictidomys tridecemlineatus	95.16	4.00e-167	580.00
IUUC-Loc-052397	Lepisosteus oculatus	65.19	1.00e-139	489.00
IUUC-Laf-054544	Loxodonta africana	90.18	0.00e+00	633.00
IUUC-Meu-056363	Macropus eugenii	58.46	6.00e-102	363.00
IUUC-Mga-059275	Meleagris gallopavo	72.41	2.00e-141	495.00
IUUC-Mmr-060906	Microcebus murinus	94.04	0.00e+00	726.00
IUUC-Mdo-062400	Monodelphis domestica	77.54	1.00e-176	612.00
IUUC-Mmu-063556	Mus musculus	96.21	0.00e+00	744.00
IUUC-Mpu-066500	Mustela putorius furo	93.85	0.00e+00	734.00
IUUC-Mlu-068074	Myotis lucifugus	92.31	0.00e+00	633.00
IUUC-Nle-069601	Nomascus leucogenys	94.04	0.00e+00	726.00
IUUC-Opr-070904	Ochotona princeps	85.11	7.00e-142	496.00
IUUC-Ont-072679	Oreochromis niloticus	55.81	9.00e-122	430.00
IUUC-Oan-073434	Ornithorhynchus anatinus	70.56	8.00e-82	296.00
IUUC-Ocu-074649	Oryctolagus cuniculus	93.22	0.00e+00	710.00
IUUC-Ola-087336	Oryzias latipes	49.74	8.00e-104	370.00
IUUC-Oga-088590	Otolemur garnettii	91.87	0.00e+00	685.00
IUUC-Oar-090178	Ovis aries	90.40	0.00e+00	650.00
IUUC-Pan-092881	Papio anubis	94.31	0.00e+00	728.00
IUUC-Pfo-096176	Poecilia formosa	54.73	5.00e-112	397.00
IUUC-Pab-098285	Pongo abelii	94.04	0.00e+00	728.00
IUUC-Pca-100888	Procavia capensis	87.43	0.00e+00	668.00
IUUC-Pva-102184	Pteropus vampyrus	78.86	2.00e-169	588.00
IUUC-Sha-106629	Sarcophilus harrisii	77.02	7.00e-154	536.00
IUUC-Ssc-116183	Sus scrofa	94.12	0.00e+00	737.00
IUUC-Tgu-116630	Taeniopygia guttata	70.68	1.00e-164	572.00
IUUC-Tru-118761	Takifugu rubripes	52.37	1.00e-115	409.00
IUUC-Tni-120651	Tetraodon nigroviridis	51.49	3.00e-59	221.00
IUUC-Ttr-128582	Tursiops truncatus	91.71	0.00e+00	685.00
IUUC-Vpa-130431	Vicugna pacos	74.46	5.00e-96	344.00
IUUC-Xtr-132655	Xenopus tropicalis	66.40	2.00e-147	515.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence