iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013274

Ensembl Protein ID

ENSBTAP00000022355.5

UniProt Accession

F1MLZ4; F1MLZ4_BOVIN

Genbank Protein ID

ENSBTAP00000022355

Protein Name

Lysosomal-trafficking regulator

Genbank Nucleotide ID

DAAA02061466

Gene Name

LYST

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000016804.5	ENSBTAT00000022355.5	ENSBTAP00000022355.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-06	28.2	3609	3641

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlr 31
           gHt+++++l f   +  +++s s+Dgt+ +WDl 
   Q: 3609 GHTEEISSL-FvckPYSIMISVSRDGTCIIWDLN 3641
           8*******9.998755789*************85 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MSTDSNSLAR EFLTDVNRLC NAVVQRVEAR EEEEEETHMA TLGQYLVHGR GFLLLTKLNS 60
IIDQALTCRE ELLTLLLSLL PLVWKIPVQE EKATDFNLPF SAGIILTKEK NSSSQRSTQE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCACTG ACAGTAACTC GTTGGCACGT GAGTTTCTGA CCGATGTCAA CCGGCTTTGC 60
AATGCAGTGG TCCAGAGAGT GGAGGCCAGG GAGGAAGAAG AGGAGGAAAC CCACATGGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR000409--BEACH_dom
IPR030464--LYST
IPR023362--PH-BEACH_dom
IPR011993--PH_dom-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50197--BEACH
PS51783--PH_BEACH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF02138--Beach
PF14844--PH_BEACH

SMART

SM01026--Beach
SM00320--WD40

Gene Ontology

GO:0015630--C:microtubule cytoskeleton
GO:0032510--P:endosome to lysosome transport via multivesicular body sorting pathway
GO:0007040--P:lysosome organization
GO:0042267--P:natural killer cell mediated cytotoxicity
GO:0043473--P:pigmentation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002188	Ailuropoda melanoleuca	90.36	0.00e+00	6977.00
IUUC-Apl-003779	Anas platyrhynchos	72.22	0.00e+00	5412.00
IUUC-Ame-010834	Astyanax mexicanus	64.64	0.00e+00	3488.00
IUUC-Cja-019682	Callithrix jacchus	90.14	0.00e+00	6876.00
IUUC-Cfa-020625	Canis familiaris	89.90	0.00e+00	6795.00
IUUC-Cpo-022515	Cavia porcellus	83.86	0.00e+00	6321.00
IUUC-Csa-023804	Chlorocebus sabaeus	90.12	0.00e+00	6875.00
IUUC-Cin-025176	Ciona intestinalis	44.44	6.00e-84	304.00
IUUC-Csv-026108	Ciona savignyi	53.27	0.00e+00	709.00
IUUC-Dre-027544	Danio rerio	63.17	0.00e+00	3340.00
IUUC-Dno-029030	Dasypus novemcinctus	87.05	0.00e+00	6651.00
IUUC-Dor-031065	Dipodomys ordii	80.00	0.00e+00	2832.00
IUUC-Eca-034391	Equus caballus	90.08	0.00e+00	6901.00
IUUC-Fal-037194	Ficedula albicollis	71.74	0.00e+00	5362.00
IUUC-Gmo-039256	Gadus morhua	74.21	0.00e+00	2303.00
IUUC-Gga-040318	Gallus gallus	72.31	0.00e+00	5378.00
IUUC-Gac-042425	Gasterosteus aculeatus	61.42	0.00e+00	4401.00
IUUC-Ggo-045550	Gorilla gorilla	89.96	0.00e+00	6838.00
IUUC-Hsa-046612	Homo sapiens	90.48	0.00e+00	6915.00
IUUC-Laf-054133	Loxodonta africana	88.28	0.00e+00	6674.00
IUUC-Mcc-055373	Macaca mulatta	90.29	0.00e+00	6906.00
IUUC-Mga-059475	Meleagris gallopavo	70.29	0.00e+00	5204.00
IUUC-Mmr-061795	Microcebus murinus	90.69	0.00e+00	6867.00
IUUC-Mlu-067930	Myotis lucifugus	84.33	0.00e+00	3764.00
IUUC-Nle-069205	Nomascus leucogenys	89.46	0.00e+00	6770.00
IUUC-Ont-071764	Oreochromis niloticus	61.89	0.00e+00	4396.00
IUUC-Ocu-074479	Oryctolagus cuniculus	87.90	0.00e+00	6664.00
IUUC-Ptr-091393	Pan troglodytes	90.37	0.00e+00	6900.00
IUUC-Pan-092369	Papio anubis	90.22	0.00e+00	6873.00
IUUC-Pfo-096100	Poecilia formosa	64.55	0.00e+00	3462.00
IUUC-Pab-098733	Pongo abelii	89.08	0.00e+00	6754.00
IUUC-Pca-100429	Procavia capensis	76.65	0.00e+00	2493.00
IUUC-Sha-106595	Sarcophilus harrisii	73.16	0.00e+00	5311.00
IUUC-Sar-113059	Sorex araneus	76.73	0.00e+00	1833.00
IUUC-Ssc-115879	Sus scrofa	85.20	0.00e+00	6297.00
IUUC-Tru-118616	Takifugu rubripes	60.84	0.00e+00	4325.00
IUUC-Tsy-119568	Tarsius syrichta	83.08	0.00e+00	5387.00
IUUC-Tni-120782	Tetraodon nigroviridis	60.50	0.00e+00	4335.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence