iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092270

Ensembl Protein ID

ENSPANP00000015532.1

UniProt Accession

A0A096NR62; A0A096NR62_PAPAN

Genbank Protein ID

ENSPANP00000015532

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01050006

Gene Name

STRN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000020091.1	ENSPANT00000022605.1	ENSPANP00000015532.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-29	101.1	556	588
UBD/Beta-Prp	4.20e-46	157.5	553	766

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlr 31
           gHtd v++la+   +  +l+s+s Dgt++vW+++
   Q: 556  GHTDAVWGLAYsaaH-QRLLSCSADGTLRVWNTT 588
           8**********9853.89**************76 PP

UBD/Beta-Prp

   S: 47   slsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk......ghedsvlslsfspsgdklvsGshdrtirvwdletgqcl 129
            l gh+++v+ + +s   + l+++s D+t++vw+     +  ++       g  +sv ++s++p  +++v+  +  +  ++++et+q +
   Q: 553  PLLGHTDAVWGLAYSAAHQRLLSCSADGTLRVWNTTEVAPALSVFndtqelGIPASVDLVSSDP--SHMVASFSKGYTSIFNMETQQRI 639
           589******************************8776655555551444555666666677777..8888888899************* PP
   S: 130  ee......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtg 212
            +      t ++ +  +n v +hp+  + ++++ Dr ++++d +tgkl++ +   h ++v+sl++d+ng +l+sgs+d +++lw+l+++
   Q: 640  LTlesnvdTTANSSCQINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVA-HLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLESK 727
           **9999998888888999999***99**************************98.********************************** PP
   S: 213  ecvrtlnght....dnvksvrfspnderlvsgssDgsir 247
           +c++++++h+    + + +v+f+p + +++s+++D   +
   Q: 728  TCIQEFTAHRkkfeESIHDVAFHPSKCYIASAGADALAK 766
           **********999999******************97655 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MDEQAGPGVF FSNNHPGAGG AKGLGPLAEA RAQYSLPGIL HFLQHEWARF EVERAQWEVE 60
RAELQAQIAF LQGERKGQEN LKKDLVRRIK MLEYALKQER AKYHKLKYGT ELNQGDMKPP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACGAGC AGGCGGGTCC CGGCGTTTTC TTCAGCAACA ACCACCCGGG CGCCGGCGGT 60
GCCAAGGGGC TCGGGCCTCT GGCGGAGGCT ACCGCGGCCG GCGACGGGGC GGCTGCGGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013258--Striatin_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08232--Striatin
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005923--C:bicellular tight junction
GO:0000159--C:protein phosphatase type 2A complex
GO:0008285--P:negative regulation of cell proliferation
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001899	Ailuropoda melanoleuca	93.92	0.00e+00	1320.00
IUUC-Apl-003927	Anas platyrhynchos	85.15	0.00e+00	1091.00
IUUC-Aca-004933	Anolis carolinensis	77.99	0.00e+00	1109.00
IUUC-Ame-010997	Astyanax mexicanus	71.99	0.00e+00	1048.00
IUUC-Bta-013077	Bos taurus	92.20	0.00e+00	1332.00
IUUC-Cja-018973	Callithrix jacchus	93.73	0.00e+00	1350.00
IUUC-Cfa-020988	Canis familiaris	90.07	0.00e+00	1184.00
IUUC-Cpo-022496	Cavia porcellus	91.82	0.00e+00	1326.00
IUUC-Csa-023829	Chlorocebus sabaeus	93.88	0.00e+00	1353.00
IUUC-Cin-025167	Ciona intestinalis	46.68	5.00e-177	614.00
IUUC-Csv-026143	Ciona savignyi	49.28	0.00e+00	642.00
IUUC-Dre-028560	Danio rerio	68.92	0.00e+00	976.00
IUUC-Dno-029742	Dasypus novemcinctus	86.70	0.00e+00	1268.00
IUUC-Dor-030721	Dipodomys ordii	84.14	0.00e+00	1202.00
IUUC-Eca-033760	Equus caballus	93.62	0.00e+00	1239.00
IUUC-Eeu-034953	Erinaceus europaeus	97.14	0.00e+00	751.00
IUUC-Fca-036530	Felis catus	93.05	0.00e+00	1240.00
IUUC-Fal-037353	Ficedula albicollis	78.58	0.00e+00	862.00
IUUC-Gga-040132	Gallus gallus	80.20	0.00e+00	1112.00
IUUC-Gac-041713	Gasterosteus aculeatus	71.99	0.00e+00	1045.00
IUUC-Ggo-045455	Gorilla gorilla	84.61	0.00e+00	1150.00
IUUC-Hsa-046415	Homo sapiens	93.48	0.00e+00	1345.00
IUUC-Lch-050475	Latimeria chalumnae	77.90	0.00e+00	1151.00
IUUC-Loc-051859	Lepisosteus oculatus	75.54	0.00e+00	1104.00
IUUC-Laf-053537	Loxodonta africana	91.43	0.00e+00	1330.00
IUUC-Mcc-055817	Macaca mulatta	93.64	0.00e+00	1353.00
IUUC-Meu-055946	Macropus eugenii	74.19	0.00e+00	683.00
IUUC-Mga-059694	Meleagris gallopavo	85.13	0.00e+00	1083.00
IUUC-Mmr-060768	Microcebus murinus	92.71	0.00e+00	1360.00
IUUC-Mdo-061901	Monodelphis domestica	83.41	0.00e+00	1278.00
IUUC-Mmu-064154	Mus musculus	91.43	0.00e+00	1321.00
IUUC-Mpu-065827	Mustela putorius furo	87.67	0.00e+00	1324.00
IUUC-Mlu-067102	Myotis lucifugus	93.49	0.00e+00	1307.00
IUUC-Ncr-068831	Neurospora crassa	39.60	6.00e-22	99.80
IUUC-Nle-070008	Nomascus leucogenys	94.61	0.00e+00	1253.00
IUUC-Ont-072025	Oreochromis niloticus	71.85	0.00e+00	1021.00
IUUC-Oan-072950	Ornithorhynchus anatinus	88.36	0.00e+00	1114.00
IUUC-Ocu-074316	Oryctolagus cuniculus	92.77	0.00e+00	1222.00
IUUC-Ola-087279	Oryzias latipes	69.39	0.00e+00	1009.00
IUUC-Oga-088284	Otolemur garnettii	92.46	0.00e+00	1327.00
IUUC-Oar-090304	Ovis aries	92.46	0.00e+00	1336.00
IUUC-Ptr-091052	Pan troglodytes	93.61	0.00e+00	1346.00
IUUC-Psi-093907	Pelodiscus sinensis	84.83	0.00e+00	1009.00
IUUC-Pfo-097042	Poecilia formosa	70.98	0.00e+00	1103.00
IUUC-Pab-098110	Pongo abelii	93.61	0.00e+00	1346.00
IUUC-Pca-100266	Procavia capensis	82.03	0.00e+00	969.00
IUUC-Pva-102824	Pteropus vampyrus	90.15	0.00e+00	1310.00
IUUC-Pgr-103483	Puccinia graminis	37.18	1.00e-55	212.00
IUUC-Rno-105638	Rattus norvegicus	91.43	0.00e+00	1321.00
IUUC-Sha-107004	Sarcophilus harrisii	85.19	0.00e+00	1087.00
IUUC-Ssc-115280	Sus scrofa	92.58	0.00e+00	1343.00
IUUC-Tgu-116759	Taeniopygia guttata	85.98	0.00e+00	1111.00
IUUC-Tru-117944	Takifugu rubripes	71.72	0.00e+00	1030.00
IUUC-Tsy-119405	Tarsius syrichta	86.64	0.00e+00	723.00
IUUC-Tni-120571	Tetraodon nigroviridis	71.01	0.00e+00	1030.00
IUUC-Vpa-130294	Vicugna pacos	93.75	0.00e+00	1240.00
IUUC-Xma-134233	Xiphophorus maculatus	66.31	0.00e+00	877.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence