iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011932

Ensembl Protein ID

ENSAMXP00000012840.1

UniProt Accession

W5KZ28; W5KZ28_ASTMX

Genbank Protein ID

ENSAMXP00000012840

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

APWO01010241

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000012476.1	ENSAMXT00000012840.1	ENSAMXP00000012840.1
ENSAMXG00000012476.1	ENSAMXT00000012843.1	ENSAMXP00000012843.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	5.10e-16	58.8	942	983

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           +C +C +gg+    l++Ce C  +fHp+Cl+++    +p+ + w+C++Crs
   Q: 942  WCFICSKGGR----LLCCESCPAAFHPDCLNIA----MPDGS-WFCNDCRS 983
           8*********....*******************....9***8.******96 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MDSKGRSLPA MPEPKNPTSM KQLSGSPGGC KGRGDGSTDP ALLLDKAAAQ IAATPQEGVL 60
QKISNHNHTH SLDHTHERLK DLTSRLLNGD QDKMPKLCAA PASPTFLKGV DAGSPHGSPQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGGATTGGA TCCCGCCCTA TTTCGTAGGA CGTCACGTGG TGAGGATGCC CTCCTTCGCT 60
CATTCGTGCA GGCCGCCCGG TTTGACTGGG CGACGGACTT TTTCCTAAAA ACAAAAACAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR006560--AWS_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51215--AWS
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00855--PWWP
PF00856--SET

SMART

SM00570--AWS
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0051216--P:cartilage development
GO:0048706--P:embryonic skeletal system development
GO:0010452--P:histone H3-K36 methylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002181	Ailuropoda melanoleuca	71.37	0.00e+00	1053.00
IUUC-Apl-003677	Anas platyrhynchos	72.52	0.00e+00	1091.00
IUUC-Aca-004278	Anolis carolinensis	67.39	0.00e+00	1068.00
IUUC-Bta-012522	Bos taurus	71.05	0.00e+00	1041.00
IUUC-Cja-018908	Callithrix jacchus	71.09	0.00e+00	1038.00
IUUC-Cfa-020894	Canis familiaris	71.22	0.00e+00	1062.00
IUUC-Cpo-021982	Cavia porcellus	71.41	0.00e+00	1056.00
IUUC-Csa-023807	Chlorocebus sabaeus	71.34	0.00e+00	1040.00
IUUC-Csv-026298	Ciona savignyi	42.86	2.00e-62	233.00
IUUC-Dre-027492	Danio rerio	83.73	0.00e+00	1296.00
IUUC-Dno-029230	Dasypus novemcinctus	61.19	0.00e+00	914.00
IUUC-Dor-031103	Dipodomys ordii	65.93	0.00e+00	908.00
IUUC-Dme-032193	Drosophila melanogaster	37.25	1.00e-118	421.00
IUUC-Ete-032488	Echinops telfairi	65.13	0.00e+00	918.00
IUUC-Eca-034066	Equus caballus	71.08	0.00e+00	1051.00
IUUC-Eeu-035199	Erinaceus europaeus	52.34	7.00e-112	399.00
IUUC-Fca-035434	Felis catus	67.65	0.00e+00	997.00
IUUC-Fal-037113	Ficedula albicollis	71.15	0.00e+00	1096.00
IUUC-Gmo-039686	Gadus morhua	75.98	0.00e+00	1129.00
IUUC-Gga-040273	Gallus gallus	72.33	0.00e+00	1093.00
IUUC-Gac-042123	Gasterosteus aculeatus	72.75	0.00e+00	1189.00
IUUC-Ggo-044643	Gorilla gorilla	70.24	0.00e+00	1045.00
IUUC-Hsa-046380	Homo sapiens	71.34	0.00e+00	1040.00
IUUC-Itr-048658	Ictidomys tridecemlineatus	68.99	0.00e+00	1028.00
IUUC-Lch-050217	Latimeria chalumnae	69.15	0.00e+00	1100.00
IUUC-Loc-052766	Lepisosteus oculatus	73.62	0.00e+00	1173.00
IUUC-Laf-053780	Loxodonta africana	70.22	0.00e+00	1052.00
IUUC-Mcc-054928	Macaca mulatta	70.24	0.00e+00	1047.00
IUUC-Mga-059576	Meleagris gallopavo	72.23	0.00e+00	1084.00
IUUC-Mmr-061045	Microcebus murinus	69.96	0.00e+00	1056.00
IUUC-Mdo-062576	Monodelphis domestica	72.23	0.00e+00	1077.00
IUUC-Mmu-063640	Mus musculus	71.68	0.00e+00	1049.00
IUUC-Mac-065303	Musa acuminata	29.07	2.00e-11	64.70
IUUC-Mpu-066512	Mustela putorius furo	71.65	0.00e+00	1058.00
IUUC-Mlu-067261	Myotis lucifugus	63.96	0.00e+00	953.00
IUUC-Nle-069896	Nomascus leucogenys	70.79	0.00e+00	973.00
IUUC-Opr-070842	Ochotona princeps	58.42	0.00e+00	863.00
IUUC-Ont-072197	Oreochromis niloticus	80.63	0.00e+00	1163.00
IUUC-Oan-073496	Ornithorhynchus anatinus	63.06	0.00e+00	934.00
IUUC-Ocu-074758	Oryctolagus cuniculus	70.35	0.00e+00	1031.00
IUUC-Obr-076085	Oryza brachyantha	44.44	8.00e-11	63.50
IUUC-Olo-080702	Oryza longistaminata	40.47	1.00e-43	171.00
IUUC-Opu-083371	Oryza punctata	43.65	3.00e-44	174.00
IUUC-Ola-087518	Oryzias latipes	61.00	0.00e+00	819.00
IUUC-Oga-088743	Otolemur garnettii	63.96	0.00e+00	953.00
IUUC-Oar-090265	Ovis aries	63.36	0.00e+00	952.00
IUUC-Ptr-091055	Pan troglodytes	71.34	0.00e+00	1040.00
IUUC-Pan-092752	Papio anubis	71.49	0.00e+00	1028.00
IUUC-Psi-093620	Pelodiscus sinensis	73.20	0.00e+00	1105.00
IUUC-Pfo-097464	Poecilia formosa	70.69	0.00e+00	1170.00
IUUC-Pab-098051	Pongo abelii	70.10	0.00e+00	1046.00
IUUC-Pop-099927	Populus trichocarpa	29.32	6.00e-12	66.20
IUUC-Pca-100273	Procavia capensis	70.16	0.00e+00	1035.00
IUUC-Ppe-101635	Prunus persica	28.49	5.00e-11	63.50
IUUC-Pva-102473	Pteropus vampyrus	68.69	0.00e+00	922.00
IUUC-Rno-105056	Rattus norvegicus	71.26	0.00e+00	1050.00
IUUC-Sha-107494	Sarcophilus harrisii	72.09	0.00e+00	1069.00
IUUC-Sit-110333	Setaria italica	28.40	1.00e-10	61.60
IUUC-Sar-113310	Sorex araneus	71.60	0.00e+00	910.00
IUUC-Ssc-116344	Sus scrofa	70.22	0.00e+00	1038.00
IUUC-Tgu-116786	Taeniopygia guttata	72.41	0.00e+00	1088.00
IUUC-Tru-117638	Takifugu rubripes	78.52	0.00e+00	1184.00
IUUC-Tsy-118937	Tarsius syrichta	64.27	0.00e+00	1023.00
IUUC-Tca-121456	Theobroma cacao	31.86	5.00e-18	86.70
IUUC-Tbe-127291	Tupaia belangeri	68.48	0.00e+00	987.00
IUUC-Xtr-132673	Xenopus tropicalis	68.88	0.00e+00	1018.00
IUUC-Xma-133695	Xiphophorus maculatus	80.49	0.00e+00	1110.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence