iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aly-005455

Ensembl Protein ID

fgenesh2_kg.1__895__AT1G08700.1

UniProt Accession

D7KIU7; D7KIU7_ARALL

Genbank Protein ID

EFH68729.1

Protein Name

Presenilin

Genbank Nucleotide ID

GL348713

Gene Name

PS1; ARALYDRAFT_470941

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
fgenesh2_kg.1__895__AT1G08700.1	fgenesh2_kg.1__895__AT1G08700.1	fgenesh2_kg.1__895__AT1G08700.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/CUE	40.52	2.00e-24	110.00	IUUC-Cel-018553

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Arabidopsis lyrata

Functional Description
(View)

Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.

Protein Sequence
(Fasta)

MESSILDSLG VEIIGVMAPV SICMFLVVLL TYSLSVTSDP QIRTAANLIY IENPSDSATV 60
KLEGSLANAI VFVVLVAAVT FILVLLFYYN FTNFLKHYMR FSAFFVSGTM GGAIFLSIIQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTAACTCTC TCCTCTCGTC TTCTTCCTCT AGAACCCCCA AAAAAATGGC GTAGCCAAAA 60
ACTCCTCCGA AATCGATAAC GATGGAGTCT AGTATTCTCG ATTCTCTCGG AGTTGAGATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0333--Golgi apparatus
KW-0378--Hydrolase
KW-0472--Membrane
KW-0914--Notch signaling pathway
KW-0645--Protease
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001108--Peptidase_A22A
IPR006639--Preselin/SPP

Pfam

PF01080--Presenilin

PRINTS

PR01072--PRESENILIN

SMART

SM00730--PSN

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0005798--C:Golgi-associated vesicle
GO:0016021--C:integral component of membrane
GO:0004190--F:aspartic-type endopeptidase activity
GO:0007219--P:Notch signaling pathway
GO:0016485--P:protein processing

KEGG

aly:ARALYDRAFT_470941

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000686	Aegilops tauschii	59.21	2.00e-45	176.00
IUUC-Aml-001648	Ailuropoda melanoleuca	33.62	7.00e-32	130.00
IUUC-Atr-003039	Amborella trichopoda	57.47	7.00e-134	469.00
IUUC-Apl-003959	Anas platyrhynchos	29.30	2.00e-20	92.80
IUUC-Aca-005160	Anolis carolinensis	29.79	2.00e-24	105.00
IUUC-Ath-006730	Arabidopsis thaliana	94.04	0.00e+00	723.00
IUUC-Ame-010686	Astyanax mexicanus	31.51	1.00e-23	103.00
IUUC-Bta-013026	Bos taurus	30.70	5.00e-34	137.00
IUUC-Bdi-014196	Brachypodium distachyon	51.51	2.00e-95	342.00
IUUC-Bol-015841	Brassica oleracea	81.60	5.00e-167	579.00
IUUC-Bra-017580	Brassica rapa	81.92	4.00e-149	520.00
IUUC-Cel-018553	Caenorhabditis elegans	32.39	1.00e-45	176.00
IUUC-Cja-019994	Callithrix jacchus	30.59	4.00e-34	138.00
IUUC-Cfa-020074	Canis familiaris	31.08	3.00e-34	139.00
IUUC-Cpo-022237	Cavia porcellus	32.56	3.00e-23	102.00
IUUC-Cre-022747	Chlamydomonas reinhardtii	44.68	1.00e-49	190.00
IUUC-Csa-023537	Chlorocebus sabaeus	30.82	1.00e-34	140.00
IUUC-Cho-024735	Choloepus hoffmanni	29.30	3.00e-21	95.90
IUUC-Cin-025780	Ciona intestinalis	29.95	2.00e-38	152.00
IUUC-Csv-025967	Ciona savignyi	31.63	4.00e-26	111.00
IUUC-Dre-028526	Danio rerio	31.16	2.00e-26	112.00
IUUC-Dno-029758	Dasypus novemcinctus	31.63	1.00e-22	100.00
IUUC-Dor-030609	Dipodomys ordii	52.94	8.00e-20	90.90
IUUC-Dme-031929	Drosophila melanogaster	31.46	2.00e-27	116.00
IUUC-Ete-032487	Echinops telfairi	32.42	7.00e-14	71.20
IUUC-Eca-033391	Equus caballus	32.19	3.00e-18	85.50
IUUC-Eeu-035134	Erinaceus europaeus	31.64	5.00e-31	127.00
IUUC-Fca-035396	Felis catus	30.70	2.00e-25	109.00
IUUC-Fal-036600	Ficedula albicollis	30.23	2.00e-21	96.30
IUUC-Gmo-038550	Gadus morhua	32.11	1.00e-24	106.00
IUUC-Gga-040706	Gallus gallus	28.39	6.00e-21	94.70
IUUC-Gac-042342	Gasterosteus aculeatus	30.70	3.00e-21	95.90
IUUC-Gma-043822	Glycine max	69.75	2.00e-56	212.00
IUUC-Ggo-044859	Gorilla gorilla	32.56	4.00e-24	104.00
IUUC-Hsa-046822	Homo sapiens	30.82	1.00e-34	140.00
IUUC-Hvu-047141	Hordeum vulgare	50.00	5.00e-88	317.00
IUUC-Itr-048420	Ictidomys tridecemlineatus	30.56	1.00e-30	126.00
IUUC-Lch-049638	Latimeria chalumnae	29.77	2.00e-25	109.00
IUUC-Lpe-051132	Leersia perrieri	52.56	2.00e-87	315.00
IUUC-Loc-052427	Lepisosteus oculatus	28.51	3.00e-25	108.00
IUUC-Laf-053979	Loxodonta africana	30.45	2.00e-30	126.00
IUUC-Mcc-055682	Macaca mulatta	30.82	1.00e-34	140.00
IUUC-Meu-056004	Macropus eugenii	30.70	1.00e-21	97.10
IUUC-Mtr-058392	Medicago truncatula	60.52	1.00e-114	405.00
IUUC-Mga-059466	Meleagris gallopavo	30.23	3.00e-21	95.90
IUUC-Mmr-060890	Microcebus murinus	29.30	2.00e-23	102.00
IUUC-Mdo-062122	Monodelphis domestica	31.16	4.00e-22	98.60
IUUC-Mmu-063176	Mus musculus	31.63	4.00e-23	101.00
IUUC-Mac-064858	Musa acuminata	66.67	2.00e-40	158.00
IUUC-Mpu-065927	Mustela putorius furo	30.86	5.00e-34	138.00
IUUC-Mlu-067079	Myotis lucifugus	31.05	3.00e-39	155.00
IUUC-Nle-070180	Nomascus leucogenys	30.82	1.00e-34	140.00
IUUC-Opr-070847	Ochotona princeps	32.39	2.00e-22	99.80
IUUC-Ont-071846	Oreochromis niloticus	30.70	2.00e-22	99.80
IUUC-Oan-072783	Ornithorhynchus anatinus	39.25	3.00e-19	88.20
IUUC-Ocu-074527	Oryctolagus cuniculus	32.56	3.00e-23	102.00
IUUC-Oba-075256	Oryza barthii	52.19	5.00e-82	297.00
IUUC-Obr-076302	Oryza brachyantha	52.35	6.00e-90	323.00
IUUC-Ogl-077097	Oryza glaberrima	51.50	6.00e-91	327.00
IUUC-Ogu-078570	Oryza glumaepatula	52.78	3.00e-87	315.00
IUUC-Oin-079244	Oryza indica	51.71	1.00e-91	329.00
IUUC-Olo-080484	Oryza longistaminata	52.15	4.00e-62	230.00
IUUC-Ome-081814	Oryza meridionalis	50.96	3.00e-92	331.00
IUUC-Oni-082057	Oryza nivara	53.03	8.00e-88	316.00
IUUC-Opu-084176	Oryza punctata	51.46	4.00e-87	314.00
IUUC-Oru-084618	Oryza rufipogon	52.78	3.00e-87	314.00
IUUC-Osa-085602	Oryza sativa	52.64	7.00e-88	317.00
IUUC-Ola-086707	Oryzias latipes	31.86	6.00e-25	107.00
IUUC-Olu-087811	Ostreococcus lucimarinus	39.83	3.00e-47	181.00
IUUC-Oga-088560	Otolemur garnettii	29.77	7.00e-24	104.00
IUUC-Oar-090348	Ovis aries	29.84	9.00e-35	140.00
IUUC-Ptr-091060	Pan troglodytes	30.82	1.00e-34	140.00
IUUC-Pan-091855	Papio anubis	32.56	2.00e-23	103.00
IUUC-Psi-093505	Pelodiscus sinensis	31.63	3.00e-22	99.40
IUUC-Pma-094612	Petromyzon marinus	29.77	3.00e-19	89.00
IUUC-Ppa-095431	Physcomitrella patens	45.10	1.00e-91	329.00
IUUC-Pfo-097396	Poecilia formosa	30.23	2.00e-21	96.30
IUUC-Pab-098591	Pongo abelii	30.82	1.00e-34	140.00
IUUC-Pop-099661	Populus trichocarpa	45.92	3.00e-83	301.00
IUUC-Pca-101029	Procavia capensis	28.92	2.00e-30	126.00
IUUC-Ppe-101495	Prunus persica	63.37	2.00e-146	511.00
IUUC-Pva-102244	Pteropus vampyrus	33.18	2.00e-24	106.00
IUUC-Rno-105861	Rattus norvegicus	32.09	6.00e-23	101.00
IUUC-Sha-107045	Sarcophilus harrisii	31.16	4.00e-22	98.60
IUUC-Smo-109325	Selaginella moellendorffii	52.47	4.00e-45	174.00
IUUC-Sit-110624	Setaria italica	48.86	7.00e-85	306.00
IUUC-Sly-110865	Solanum lycopersicum	85.71	2.00e-30	123.00
IUUC-Stu-112433	Solanum tuberosum	59.57	4.00e-116	410.00
IUUC-Sar-113169	Sorex araneus	32.64	5.00e-31	128.00
IUUC-Sbi-114305	Sorghum bicolor	50.73	5.00e-87	313.00
IUUC-Ssc-115766	Sus scrofa	31.75	3.00e-35	142.00
IUUC-Tgu-117280	Taeniopygia guttata	31.16	6.00e-23	101.00
IUUC-Tru-117732	Takifugu rubripes	29.55	1.00e-32	133.00
IUUC-Tsy-119624	Tarsius syrichta	32.09	7.00e-23	100.00
IUUC-Tni-119852	Tetraodon nigroviridis	30.23	4.00e-21	95.50
IUUC-Tca-121865	Theobroma cacao	68.61	1.00e-144	505.00
IUUC-Tae-125925	Triticum aestivum	51.29	2.00e-87	315.00
IUUC-Tur-126237	Triticum urartu	89.77	6.00e-42	164.00
IUUC-Tbe-128148	Tupaia belangeri	31.31	1.00e-22	100.00
IUUC-Ttr-128793	Tursiops truncatus	30.59	6.00e-32	131.00
IUUC-Vpa-130625	Vicugna pacos	40.95	1.00e-19	90.50
IUUC-Vvi-131312	Vitis vinifera	61.36	5.00e-132	463.00
IUUC-Xtr-131790	Xenopus tropicalis	29.80	1.00e-32	133.00
IUUC-Xma-133377	Xiphophorus maculatus	30.23	3.00e-21	95.50

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence