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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Cel-018408
UUCD1 version UUC-CaE-00393
Ensembl Protein ID F52A8.2a
UniProt Accession Q20636; GBB2_CAEEL
Genbank Protein ID AAK55964.1; CAA95824.1
Protein Name Guanine nucleotide-binding protein subunit beta-2
Genbank Nucleotide ID AF291847; Z71263
Gene Name gpb-2; F52A8.2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00001680 F52A8.2a F52A8.2a
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNAmiRNAMapRAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.40e-40 135.1 167 205
UBD/Beta-Prp 2.00e-49 168.7 163 368
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllk 37
           +Ht+ ++c+ f  sd+l+++Gs+D t+ +WD+ +g l++
   Q: 167  THTSYMSCCTFlrSDNLILTGSGDSTCAIWDVESGQLIQ 205
           5***********999******************998876 PP
   

   UBD/Beta-Prp
   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvv 144
           r++  h++  ++++f +++++++tgs D t  +wd+++g+ ++ ++gh+ +v ++++ +  +g++++s+++d+   vwd+++gqc++  ++gh++ +n+v+
   Q: 163  RQVATHTSYMSCCTFLRSDNLILTGSGDSTCAIWDVESGQLIQNFHGHTGDVFAIDVPKcdTGNTFISAGADKHSLVWDIRSGQCVQ-SFEGHEADINTVR 262
           6788999999***********************************************999788***********************9.************* PP
   S: 145  vhpdgnllvsGslDrtvrlWdlktgk..llrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssD 243
           +hp+g+ +++Gs+D t+rl+dl+ ++  ++++ ++    +v+ ++f+ +g+ l +g  d +v +wd  +      l gh++ ++++r+sp+++ + s+s D
   Q: 263  FHPNGDAFATGSDDATCRLFDLRADRqvCVYEKES-ILFPVNGVDFSLSGRILFAGYGDYRVGVWDSLKCARHSVLYGHENRISCLRTSPDGTAVCSASWD 362
           **********************6655115565566.8899**************************998888999************************** PP
   S: 244  gsiriW 249
            +iriW
   Q: 363  CTIRIW 368
           *****9 PP
   
Organism Caenorhabditis elegans
Functional Description
(View)

Functional Description


     G proteins are composed of 3 units, alpha, beta and gamma (By similarity). Interacts with G protein gamma subunits gpc-1 and gpc-2 and with egl-10 and eat-16 (PubMed:11333232).
 G proteins are composed of 3 units, alpha, beta and gamma (By similarity). Interacts with G protein gamma subunits gpc-1 and gpc-2 and with egl-10 and eat-16 (PubMed:11333232).
Protein Sequence
(Fasta)
MSTIAGESSS SSKMPENSQP TTTEKGSEYL EQLANEAEEL RKKLDQERHK LNDIPIQQAA 60
ERLDVMGALG VKQRRILKGH VGKVLCMDWS LDKRHIVSSS QDGKVIVWDG FTTNKEHALT 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cel-018408|E3,WD_repeat;UBD,Beta-Prp|Caenorhabditis elegans
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAAAAATGTG CCTCTAAACC TCAAACAAAC CGCCCATCTC TAATTGTTCT ATTCAAATTC 60
ATTTTCTTCA ACCCTCAGTC TTCTCTTCCT TTTTTTGCAT AATTCGTCTT CTGATCTCAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cel-018408|E3,WD_repeat;UBD,Beta-Prp|Caenorhabditis elegans
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0807--Transducer
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0043025--C:neuronal cell body
GO:0004871--F:signal transducer activity
GO:0007212--P:dopamine receptor signaling pathway
GO:0007631--P:feeding behavior
GO:0007213--P:G-protein coupled acetylcholine receptor signaling pathway
GO:0008277--P:regulation of G-protein coupled receptor protein signaling pathway
GO:0040012--P:regulation of locomotion
GO:0046662--P:regulation of oviposition
GO:0043051--P:regulation of pharyngeal pumping
GO:0032094--P:response to food
KEGG cel:CELE_F52A8.2
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001811 Ailuropoda melanoleuca 63.80 6.00e-134 469.00
IUUC-Apl-003399 Anas platyrhynchos 66.13 6.00e-129 452.00
IUUC-Aca-004861 Anolis carolinensis 65.99 2.00e-142 497.00
IUUC-Ame-011851 Astyanax mexicanus 63.27 4.00e-136 476.00
IUUC-Bta-012438 Bos taurus 64.64 8.00e-140 488.00
IUUC-Cja-019086 Callithrix jacchus 64.72 3.00e-138 483.00
IUUC-Cfa-021255 Canis familiaris 65.84 3.00e-132 463.00
IUUC-Cpo-021398 Cavia porcellus 65.03 1.00e-138 484.00
IUUC-Csa-023776 Chlorocebus sabaeus 64.93 4.00e-140 489.00
IUUC-Cin-025305 Ciona intestinalis 56.01 5.00e-123 432.00
IUUC-Csv-026058 Ciona savignyi 56.08 8.00e-117 412.00
IUUC-Dre-028572 Danio rerio 62.08 1.00e-136 478.00
IUUC-Dor-031013 Dipodomys ordii 65.62 2.00e-105 374.00
IUUC-Dme-031889 Drosophila melanogaster 62.10 5.00e-140 489.00
IUUC-Eca-033977 Equus caballus 64.88 2.00e-135 473.00
IUUC-Eeu-035079 Erinaceus europaeus 64.93 6.00e-140 489.00
IUUC-Fca-035693 Felis catus 59.89 5.00e-133 466.00
IUUC-Fal-037345 Ficedula albicollis 65.22 4.00e-140 489.00
IUUC-Gmo-039222 Gadus morhua 64.81 2.00e-131 460.00
IUUC-Gga-040320 Gallus gallus 65.22 2.00e-140 490.00
IUUC-Gac-042644 Gasterosteus aculeatus 62.05 4.00e-138 483.00
IUUC-Ggo-044489 Gorilla gorilla 66.25 2.00e-131 460.00
IUUC-Hsa-046434 Homo sapiens 64.93 7.00e-140 488.00
IUUC-Itr-048771 Ictidomys tridecemlineatus 62.66 2.00e-119 420.00
IUUC-Loc-052790 Lepisosteus oculatus 65.42 5.00e-132 463.00
IUUC-Laf-054255 Loxodonta africana 64.72 1.00e-137 481.00
IUUC-Mcc-055610 Macaca mulatta 64.72 3.00e-138 483.00
IUUC-Meu-056819 Macropus eugenii 64.74 2.00e-122 431.00
IUUC-Mga-059740 Meleagris gallopavo 66.46 4.00e-131 459.00
IUUC-Mmr-061221 Microcebus murinus 65.22 6.00e-140 489.00
IUUC-Mdo-062619 Monodelphis domestica 64.93 1.00e-140 490.00
IUUC-Mmu-064266 Mus musculus 64.64 1.00e-139 488.00
IUUC-Mpu-065766 Mustela putorius furo 68.11 4.00e-127 446.00
IUUC-Mlu-067221 Myotis lucifugus 62.36 2.00e-132 464.00
IUUC-Nle-069515 Nomascus leucogenys 66.35 3.00e-132 462.00
IUUC-Opr-070195 Ochotona princeps 57.97 3.00e-118 416.00
IUUC-Ont-071535 Oreochromis niloticus 62.07 9.00e-118 415.00
IUUC-Ocu-074666 Oryctolagus cuniculus 68.44 9.00e-128 448.00
IUUC-Ola-086578 Oryzias latipes 64.89 1.00e-129 454.00
IUUC-Oga-089090 Otolemur garnettii 64.55 6.00e-138 482.00
IUUC-Oar-090017 Ovis aries 65.93 1.00e-129 454.00
IUUC-Ptr-091280 Pan troglodytes 64.85 3.00e-131 459.00
IUUC-Pan-092198 Papio anubis 66.35 4.00e-132 462.00
IUUC-Psi-093030 Pelodiscus sinensis 62.57 3.00e-132 463.00
IUUC-Pfo-097182 Poecilia formosa 65.12 5.00e-132 462.00
IUUC-Pab-098157 Pongo abelii 64.93 8.00e-140 489.00
IUUC-Pva-102232 Pteropus vampyrus 56.73 6.00e-116 409.00
IUUC-Rno-105526 Rattus norvegicus 61.92 4.00e-130 456.00
IUUC-Sha-106754 Sarcophilus harrisii 65.94 4.00e-132 462.00
IUUC-Ssc-115390 Sus scrofa 64.45 2.00e-138 484.00
IUUC-Tgu-117377 Taeniopygia guttata 66.04 5.00e-130 456.00
IUUC-Tru-117938 Takifugu rubripes 65.31 2.00e-130 457.00
IUUC-Tsy-119392 Tarsius syrichta 56.76 2.00e-114 404.00
IUUC-Tni-119834 Tetraodon nigroviridis 61.68 5.00e-118 416.00
IUUC-Tbe-127469 Tupaia belangeri 64.06 2.00e-132 464.00
IUUC-Ttr-128252 Tursiops truncatus 64.53 6.00e-138 482.00
IUUC-Vpa-130173 Vicugna pacos 62.11 2.00e-94 337.00
IUUC-Xtr-131803 Xenopus tropicalis 65.62 2.00e-131 460.00
Created Date 25-Jun-2017

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