iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059927

UUCD1 version

UUC-MeG-00485

Ensembl Protein ID

ENSMGAP00000010871.1

UniProt Accession

G1NDE8; G1NDE8_MELGA

Protein Name

Uncharacterized protein

Gene Name

KLHL7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000010450.1	ENSMGAT00000011736.1	ENSMGAP00000010871.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.40e-18	66.7	44	110
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	3.80e-14	51.6	144	174

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +Dvil v++++++ah++vLa++S++F+ +f++++ esk + +ve+kd +p+  ++l++F Yt +++ n
   Q: 44   CDVILMVQERRIPAHRVVLASASHFFNLMFTTNMLESK-SFEVELKDAEPDIIEQLVEFAYTARISVN 110
           9*************************************.*************************9876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
           +Nclgi  +A+++dcp+Lk  a+dfi++hF+
   Q: 144  SNCLGISVLAECLDCPELKATADDFIHQHFT 174
           8*****************************7 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MAAPGSEKSS KKKTEKKLAA REEAKLLAGF MGVMNSMRKQ RTLCDVILMV QERRIPAHRV 60
VLASASHFFN LMFTTNMLES KSFEVELKDA EPDIIEQLVE FAYTARISVN SNNVQSLLDA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCCCGGCGA AAGCGAGAGC CCGAGGCGAC CGCTCGTCGC CCGCCGTCGC ATGCCCTCCG 60
TGGACGGAGG TGGCGGGTCC GCGGTGCCGG CGGTGAGGGG CCATGGCCGC CCCCGGCTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030599--KLHL7
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0016567--P:protein ubiquitination

KEGG

mgp:100548141

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001981	Ailuropoda melanoleuca	98.46	0.00e+00	1168.00
IUUC-Apl-003183	Anas platyrhynchos	99.46	0.00e+00	1165.00
IUUC-Aca-004273	Anolis carolinensis	97.44	0.00e+00	1161.00
IUUC-Ame-011343	Astyanax mexicanus	83.19	0.00e+00	968.00
IUUC-Bta-012785	Bos taurus	98.29	0.00e+00	1166.00
IUUC-Cja-019038	Callithrix jacchus	98.12	0.00e+00	1185.00
IUUC-Cfa-020774	Canis familiaris	98.90	0.00e+00	1142.00
IUUC-Cpo-021716	Cavia porcellus	98.21	0.00e+00	1157.00
IUUC-Csa-023029	Chlorocebus sabaeus	98.29	0.00e+00	1167.00
IUUC-Cho-024947	Choloepus hoffmanni	75.45	0.00e+00	842.00
IUUC-Dre-028014	Danio rerio	83.40	0.00e+00	877.00
IUUC-Dno-029946	Dasypus novemcinctus	98.29	0.00e+00	1166.00
IUUC-Dor-030916	Dipodomys ordii	81.54	2.00e-174	605.00
IUUC-Dse-031294	Dothistroma septosporum	34.09	1.00e-06	45.40
IUUC-Ete-032454	Echinops telfairi	93.69	0.00e+00	636.00
IUUC-Eca-034041	Equus caballus	98.46	0.00e+00	1167.00
IUUC-Eeu-034627	Erinaceus europaeus	97.84	0.00e+00	960.00
IUUC-Fca-035854	Felis catus	98.46	0.00e+00	1168.00
IUUC-Fal-036883	Ficedula albicollis	98.97	0.00e+00	1165.00
IUUC-Gmo-038902	Gadus morhua	78.56	0.00e+00	899.00
IUUC-Gga-040866	Gallus gallus	100.00	0.00e+00	1176.00
IUUC-Gac-041428	Gasterosteus aculeatus	77.96	0.00e+00	939.00
IUUC-Ggo-044846	Gorilla gorilla	93.78	0.00e+00	1073.00
IUUC-Hsa-047034	Homo sapiens	98.29	0.00e+00	1167.00
IUUC-Itr-048807	Ictidomys tridecemlineatus	97.88	2.00e-138	484.00
IUUC-Lch-049815	Latimeria chalumnae	89.48	0.00e+00	1054.00
IUUC-Loc-052232	Lepisosteus oculatus	84.57	0.00e+00	914.00
IUUC-Laf-053520	Loxodonta africana	98.46	0.00e+00	1168.00
IUUC-Mcc-055237	Macaca mulatta	98.12	0.00e+00	1167.00
IUUC-Meu-056095	Macropus eugenii	92.58	8.00e-176	608.00
IUUC-Mmr-060974	Microcebus murinus	97.15	0.00e+00	1146.00
IUUC-Mdo-062729	Monodelphis domestica	91.12	0.00e+00	1108.00
IUUC-Mmu-063841	Mus musculus	97.31	0.00e+00	1149.00
IUUC-Mpu-066524	Mustela putorius furo	95.83	0.00e+00	1155.00
IUUC-Mlu-067215	Myotis lucifugus	98.57	0.00e+00	1165.00
IUUC-Nle-069341	Nomascus leucogenys	98.29	0.00e+00	1167.00
IUUC-Opr-070269	Ochotona princeps	98.21	0.00e+00	1164.00
IUUC-Ont-071551	Oreochromis niloticus	79.61	0.00e+00	941.00
IUUC-Oan-072718	Ornithorhynchus anatinus	98.73	0.00e+00	1147.00
IUUC-Ocu-074287	Oryctolagus cuniculus	98.29	0.00e+00	1167.00
IUUC-Ola-086718	Oryzias latipes	78.19	0.00e+00	953.00
IUUC-Oga-088757	Otolemur garnettii	97.78	0.00e+00	1165.00
IUUC-Oar-090309	Ovis aries	98.29	0.00e+00	1166.00
IUUC-Ptr-090509	Pan troglodytes	98.29	0.00e+00	1167.00
IUUC-Pan-092929	Papio anubis	98.29	0.00e+00	1167.00
IUUC-Psi-092941	Pelodiscus sinensis	99.28	0.00e+00	1168.00
IUUC-Pfo-097421	Poecilia formosa	79.39	0.00e+00	932.00
IUUC-Pab-097792	Pongo abelii	98.29	0.00e+00	1167.00
IUUC-Pca-101033	Procavia capensis	88.79	0.00e+00	850.00
IUUC-Pva-102364	Pteropus vampyrus	88.53	0.00e+00	1023.00
IUUC-Rno-105596	Rattus norvegicus	97.13	0.00e+00	1150.00
IUUC-Sha-106815	Sarcophilus harrisii	98.88	0.00e+00	1123.00
IUUC-Smo-109320	Selaginella moellendorffii	25.45	1.00e-15	78.20
IUUC-Sar-113305	Sorex araneus	98.92	0.00e+00	1169.00
IUUC-Ssc-115871	Sus scrofa	95.17	4.00e-168	582.00
IUUC-Tgu-116940	Taeniopygia guttata	98.63	0.00e+00	1161.00
IUUC-Tru-118682	Takifugu rubripes	78.51	0.00e+00	956.00
IUUC-Tsy-118787	Tarsius syrichta	98.68	0.00e+00	800.00
IUUC-Tni-120224	Tetraodon nigroviridis	78.35	0.00e+00	961.00
IUUC-Tbe-127633	Tupaia belangeri	56.74	1.00e-87	315.00
IUUC-Ttr-128500	Tursiops truncatus	97.85	0.00e+00	1154.00
IUUC-Vpa-130512	Vicugna pacos	96.35	0.00e+00	1114.00
IUUC-Xtr-131983	Xenopus tropicalis	96.77	0.00e+00	1146.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence