iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045417

UUCD1 version

UUC-GoG-00481

Ensembl Protein ID

ENSGGOP00000012116.2

UniProt Accession

G3R9N0; G3R9N0_GORGO

Protein Name

Uncharacterized protein

Gene Name

RNF146

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000012420.2	ENSGGOT00000012463.2	ENSGGOP00000012116.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	99.07	3.00e-158	555.00	IUUC-Hsa-045790

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MMAGCGEIDH SINMLPTNRK ANESCSNTAP SLSVPECAIC LQTCVHPVSL PCKHVFCYLC 60
VKGASWLGKR CALCRQEIPE DFLDKPTLLS PEELKAASRG NGEYAWYYEG RNGWWQYDER 120

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Nucleotide Sequence
(Fasta)

ATGTAAGTGT AGCATCATGG TTTTTTTCAG TGCTGCAGTA AATTAAATGG ATTGGTTTAA 60
AGTGTGGTAA ATTGAGTATC TGTCATATTT AGTTTTAATT ATATTAAGTG AGCATTTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033509--RNF146
IPR004170--WWE-dom
IPR018123--WWE-dom_subgr
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50918--WWE
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02825--WWE

SMART

SM00184--RING
SM00678--WWE

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0072572--F:poly-ADP-D-ribose binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002237	Ailuropoda melanoleuca	90.06	6.00e-153	533.00
IUUC-Apl-004143	Anas platyrhynchos	83.47	6.00e-134	470.00
IUUC-Aca-004557	Anolis carolinensis	79.89	1.00e-127	449.00
IUUC-Ame-011088	Astyanax mexicanus	61.09	1.00e-83	303.00
IUUC-Bta-012639	Bos taurus	91.16	3.00e-149	520.00
IUUC-Cel-018462	Caenorhabditis elegans	28.35	6.00e-19	87.40
IUUC-Cja-019397	Callithrix jacchus	98.07	7.00e-165	573.00
IUUC-Cfa-021140	Canis familiaris	90.33	3.00e-165	573.00
IUUC-Cpo-021387	Cavia porcellus	88.95	4.00e-165	573.00
IUUC-Csa-023503	Chlorocebus sabaeus	93.48	1.00e-155	542.00
IUUC-Cho-024895	Choloepus hoffmanni	92.18	1.00e-142	498.00
IUUC-Cin-025455	Ciona intestinalis	51.92	3.00e-43	167.00
IUUC-Dre-028824	Danio rerio	45.64	2.00e-82	298.00
IUUC-Dno-029269	Dasypus novemcinctus	94.48	8.00e-161	559.00
IUUC-Dor-030592	Dipodomys ordii	92.84	2.00e-162	564.00
IUUC-Dme-031618	Drosophila melanogaster	57.33	1.00e-55	210.00
IUUC-Ete-032478	Echinops telfairi	90.88	5.00e-162	563.00
IUUC-Eca-033389	Equus caballus	94.74	2.00e-179	620.00
IUUC-Fca-035488	Felis catus	94.46	2.00e-162	564.00
IUUC-Fal-037087	Ficedula albicollis	83.20	1.00e-153	535.00
IUUC-Gga-040401	Gallus gallus	84.57	5.00e-138	483.00
IUUC-Gac-042412	Gasterosteus aculeatus	64.53	1.00e-87	316.00
IUUC-Hsa-045790	Homo sapiens	98.34	2.00e-165	575.00
IUUC-Itr-048820	Ictidomys tridecemlineatus	93.35	3.00e-164	570.00
IUUC-Lch-049493	Latimeria chalumnae	68.51	6.00e-110	390.00
IUUC-Loc-052927	Lepisosteus oculatus	60.55	5.00e-103	367.00
IUUC-Laf-053904	Loxodonta africana	92.54	2.00e-158	551.00
IUUC-Mcc-055427	Macaca mulatta	92.84	4.00e-162	563.00
IUUC-Mmr-060580	Microcebus murinus	95.32	1.00e-158	552.00
IUUC-Mdo-062094	Monodelphis domestica	96.21	2.00e-78	283.00
IUUC-Mmu-063363	Mus musculus	91.16	6.00e-163	566.00
IUUC-Mpu-066816	Mustela putorius furo	93.92	1.00e-156	545.00
IUUC-Mlu-067433	Myotis lucifugus	93.65	7.00e-178	616.00
IUUC-Nle-068986	Nomascus leucogenys	97.51	1.00e-178	618.00
IUUC-Ont-072670	Oreochromis niloticus	58.42	3.00e-81	295.00
IUUC-Oan-073330	Ornithorhynchus anatinus	87.06	3.00e-107	380.00
IUUC-Ocu-074161	Oryctolagus cuniculus	92.01	2.00e-163	568.00
IUUC-Ola-086902	Oryzias latipes	59.27	2.00e-84	305.00
IUUC-Oga-089159	Otolemur garnettii	92.82	0.00e+00	635.00
IUUC-Oar-089586	Ovis aries	93.09	2.00e-145	508.00
IUUC-Ptr-090987	Pan troglodytes	98.34	2.00e-165	575.00
IUUC-Pan-091867	Papio anubis	92.82	3.00e-161	560.00
IUUC-Psi-094024	Pelodiscus sinensis	83.75	2.00e-141	495.00
IUUC-Pma-094453	Petromyzon marinus	63.91	3.00e-65	241.00
IUUC-Pfo-097108	Poecilia formosa	71.22	6.00e-84	304.00
IUUC-Pab-097997	Pongo abelii	96.40	2.00e-171	594.00
IUUC-Pca-100260	Procavia capensis	90.86	3.00e-163	567.00
IUUC-Pva-103140	Pteropus vampyrus	93.39	2.00e-163	568.00
IUUC-Rno-105795	Rattus norvegicus	85.67	1.00e-162	565.00
IUUC-Sha-107033	Sarcophilus harrisii	87.33	6.00e-155	540.00
IUUC-Ssc-116395	Sus scrofa	95.86	4.00e-179	620.00
IUUC-Tgu-116685	Taeniopygia guttata	82.09	2.00e-134	471.00
IUUC-Tru-118014	Takifugu rubripes	64.84	3.00e-84	304.00
IUUC-Tsy-119326	Tarsius syrichta	88.71	3.00e-174	603.00
IUUC-Tni-120322	Tetraodon nigroviridis	70.42	4.00e-82	297.00
IUUC-Tbe-128067	Tupaia belangeri	94.21	1.00e-169	588.00
IUUC-Ttr-128530	Tursiops truncatus	95.32	5.00e-163	566.00
IUUC-Vpa-130322	Vicugna pacos	96.13	1.00e-169	588.00
IUUC-Xtr-132606	Xenopus tropicalis	65.93	3.00e-118	417.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence