iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049722

Ensembl Protein ID

ENSLACP00000013577.1

UniProt Accession

H3AVA6; H3AVA6_LATCH

Genbank Protein ID

ENSLACP00000013577

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01131280

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000011954.1	ENSLACT00000013673.1	ENSLACP00000013577.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-23	82.5	531	557
UBD/Beta-Prp	4.00e-40	138.1	483	789

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 5    svtclaf..sdtllvsGsdDgtikvWD 29
           ++t++a+  s+t+l +Gs Dgt+k+WD
   Q: 531  EITAMALnySETRLFTGSTDGTVKIWD 557
           68999998777**************** PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgh..eaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk.gh 93
           +h ++it v +    ++++++   +t++ w ++tg++++++ g+  +ae+ta+ ++ ++  l tgs+D+t+k+wd++ g c h+l+ g 
   Q: 483  SHANPITFVLYNSTFKQVISSDSGSTVTFWMIDTGQKIKQFTGChgKAEITAMALNYSETRLFTGSTDGTVKIWDFN-GHCHHKLNaGR 570
           7999*******888889999999******************87622567*********99****************6.56777776688 PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgq.clee.....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl. 175
           +++v   ++   + ++++ ++ r+i v+ ++t + cl +        +h++ + c+++ p   l   Gs+D+ + +W+ +t++  r+l 
   Q: 571  NKEVDISQILLLKRTILVIGWERIITVFRTNTLTrCLVQplewkGGVQHHDDILCAAFLPPHTLATEGSYDGEIIIWNNNTENASRKLh 659
           88888888888889999999********9999763666688877556788889999999989999**************9999999994 PP
   S: 176  ...........tgghtdsvyslsfdsng........................................................kelvs 197
                                      +                                                          lvs
   Q: 660  pdvkralksksD---------------SqlpqqqdsttrchshsppgrrvasalnpnsfdsecnyavtrlvfletrknissagaANLVS 733
           444444433330...............2233333444444445555555555555555888889999999999999************* PP
   S: 198  gsldgtvklwdlqtgecvrtlnghtdnvksvrfs.pnderlvsgssDgsiriWdlr 252
           ++  g v++w++ +++   ++ +h+++ + v +  + +++l+sg   g +++W+++
   Q: 734  CGASGFVRFWNIFRNHLQAEFAAHSETGSIVMTVdKSEQYLISGDFSGWVKVWNIQ 789
           *************************999988777578899**************98 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

CSRQPKATET ARPQHPLAPS EMERAEAAKD VLDLLENRLK SEDFVAMQRV FMPPDLKEPV 60
SMTREEFMEK MSAAIGHGLK DEYGELFDKI DVSRDGLIDW DKLTSFMLLE LYEKDERAKT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTTCTAGAC AGGCAAGTCC CGCTTTCCAC ATCAGCCGCG GACTGCAATT GAGTGACGTC 60
CGCAAGAAAA CAGCAAACCC TTACCGCTAG CCAAAAGCTA CTGAAACTGC CCGGCCTCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011992--EF-hand-dom_pair
IPR002048--EF_hand_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50222--EF_HAND_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005509--F:calcium ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002386	Ailuropoda melanoleuca	62.30	0.00e+00	1048.00
IUUC-Aca-005140	Anolis carolinensis	54.33	0.00e+00	1090.00
IUUC-Ame-011677	Astyanax mexicanus	57.32	2.00e-124	438.00
IUUC-Bta-013449	Bos taurus	52.82	0.00e+00	744.00
IUUC-Cja-019381	Callithrix jacchus	52.92	0.00e+00	714.00
IUUC-Cfa-020449	Canis familiaris	53.88	0.00e+00	1127.00
IUUC-Csa-023219	Chlorocebus sabaeus	47.90	2.00e-130	458.00
IUUC-Cho-024437	Choloepus hoffmanni	69.12	2.00e-86	313.00
IUUC-Cin-025263	Ciona intestinalis	44.92	0.00e+00	904.00
IUUC-Dno-029512	Dasypus novemcinctus	53.21	0.00e+00	1091.00
IUUC-Dor-030182	Dipodomys ordii	59.49	3.00e-166	578.00
IUUC-Ete-033152	Echinops telfairi	50.49	0.00e+00	670.00
IUUC-Eca-033848	Equus caballus	54.29	5.00e-114	403.00
IUUC-Eeu-034535	Erinaceus europaeus	51.53	5.00e-147	514.00
IUUC-Fca-036363	Felis catus	62.55	0.00e+00	1049.00
IUUC-Gac-042429	Gasterosteus aculeatus	43.88	4.00e-104	371.00
IUUC-Ggo-045225	Gorilla gorilla	53.10	0.00e+00	775.00
IUUC-Hsa-046739	Homo sapiens	53.28	0.00e+00	729.00
IUUC-Itr-047862	Ictidomys tridecemlineatus	59.88	0.00e+00	638.00
IUUC-Loc-052665	Lepisosteus oculatus	58.44	0.00e+00	1241.00
IUUC-Laf-054050	Loxodonta africana	50.52	6.00e-164	570.00
IUUC-Meu-056792	Macropus eugenii	54.42	1.00e-154	540.00
IUUC-Mmr-060714	Microcebus murinus	60.66	0.00e+00	637.00
IUUC-Mdo-062938	Monodelphis domestica	62.00	0.00e+00	669.00
IUUC-Mmu-063645	Mus musculus	51.95	0.00e+00	721.00
IUUC-Mpu-066015	Mustela putorius furo	54.49	0.00e+00	1127.00
IUUC-Mlu-068140	Myotis lucifugus	51.93	0.00e+00	662.00
IUUC-Nle-069533	Nomascus leucogenys	52.91	0.00e+00	696.00
IUUC-Opr-070439	Ochotona princeps	48.13	5.00e-149	521.00
IUUC-Oan-073559	Ornithorhynchus anatinus	55.98	8.00e-79	286.00
IUUC-Ocu-074202	Oryctolagus cuniculus	60.67	0.00e+00	699.00
IUUC-Ola-086882	Oryzias latipes	43.16	5.00e-109	387.00
IUUC-Oga-087999	Otolemur garnettii	54.17	0.00e+00	906.00
IUUC-Oar-090438	Ovis aries	55.00	0.00e+00	1144.00
IUUC-Ptr-090859	Pan troglodytes	53.13	0.00e+00	706.00
IUUC-Pan-092049	Papio anubis	59.50	5.00e-156	543.00
IUUC-Psi-093625	Pelodiscus sinensis	57.42	0.00e+00	816.00
IUUC-Pab-098444	Pongo abelii	63.94	9.00e-175	606.00
IUUC-Pca-100464	Procavia capensis	43.49	4.00e-105	375.00
IUUC-Pva-102863	Pteropus vampyrus	52.92	0.00e+00	736.00
IUUC-Rno-105493	Rattus norvegicus	50.00	0.00e+00	687.00
IUUC-Sha-107206	Sarcophilus harrisii	50.63	0.00e+00	672.00
IUUC-Sar-113119	Sorex araneus	38.92	5.00e-119	421.00
IUUC-Ssc-116181	Sus scrofa	62.05	0.00e+00	1050.00
IUUC-Tru-118700	Takifugu rubripes	41.18	4.00e-93	335.00
IUUC-Tsy-119608	Tarsius syrichta	46.41	4.00e-169	588.00
IUUC-Tni-120461	Tetraodon nigroviridis	43.43	6.00e-99	353.00
IUUC-Tbe-127509	Tupaia belangeri	58.02	5.00e-176	610.00
IUUC-Ttr-128571	Tursiops truncatus	58.94	8.00e-158	550.00
IUUC-Vpa-130340	Vicugna pacos	51.25	0.00e+00	689.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence