iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090438

Ensembl Protein ID

ENSOARP00000001428.1

UniProt Accession

W5NTD7; W5NTD7_SHEEP

Genbank Protein ID

ENSOARP00000001428

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01009942

Gene Name

WDR49

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000001367.1	ENSOART00000001468.1	ENSOARP00000001428.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-25	88.6	634	664
UBD/Beta-Prp	3.00e-42	145.0	497	672

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sdtllvsGsdDgtikvWDlr 31
           H d++ c af +  +lv+Gs+Dg i +W+ +
   Q: 634  HHDDILCAAFsPPQTLVTGSYDGEIVLWNNS 664
           8999******844889************965 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgh..eaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk.g 92
           ++hk+ +tcv +    ++++++   +t+  w ++tg++++++ g+  +ae++++ ++ ++  l+tgs+D+t+kvwdl+ g+c htl+ g
   Q: 497  TSHKKAVTCVLYNSVLKQVISSDVGSTVSFWMIDTGQKIKQFTGChgNAEISTMALDANETRLLTGSTDGTVKVWDLN-GCCHHTLNvG 584
           578999999***999999************************7762256799999999999****************5.8899999944 PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqclee.......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           +   v   ++   +++++++++dr i v+  ++   ++           +h++ + c++++p  + lv+Gs+D+ + lW+ +t++  + 
   Q: 585  QAGAVDISHILVLKKTILVTGWDRSITVFRPQNFNQFSIqpeewkgGI-QHHDDILCAAFSP-PQTLVTGSYDGEIVLWNNSTENAHYV 671
           44444444455588**************88888888876777777444.5555556666655.599*************9988877666 PP
   S: 175  l 175
           l
   Q: 672  L 672
           6 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MSCQNATPGL NKGSQPWPEN LEKNSHGATA KEDASTVLLE KQLTLGDFVQ IQRAFEIAYL 60
ELKSHQPPEP SQTICMSREE FVQRMTEIVG WGTKEEYGEL FDKVDVAQEG FINWDKLTSF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGCTGAATT GTCCTTTTAA AAAACCCCAA TGTTTACATT GTTTAGTCAA ACCTTCAGGT 60
CAGTCCTTAG CTGCTGGCAG GATGGGGGTG TAAAGAGGAG GAGAAAAAGG AGAAGCCTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR002048--EF_hand_dom
IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50222--EF_HAND_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005509--F:calcium ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002386	Ailuropoda melanoleuca	85.82	0.00e+00	1402.00
IUUC-Aca-005140	Anolis carolinensis	54.35	0.00e+00	1070.00
IUUC-Ame-011677	Astyanax mexicanus	56.49	6.00e-118	417.00
IUUC-Bta-013449	Bos taurus	95.56	0.00e+00	1390.00
IUUC-Cja-019381	Callithrix jacchus	78.55	0.00e+00	1115.00
IUUC-Cfa-020449	Canis familiaris	79.91	0.00e+00	1701.00
IUUC-Csa-023219	Chlorocebus sabaeus	77.11	0.00e+00	771.00
IUUC-Cho-024437	Choloepus hoffmanni	93.55	5.00e-120	425.00
IUUC-Cin-025263	Ciona intestinalis	43.10	0.00e+00	807.00
IUUC-Csv-026326	Ciona savignyi	25.29	9.00e-42	164.00
IUUC-Dre-027573	Danio rerio	27.26	1.00e-69	258.00
IUUC-Dno-029512	Dasypus novemcinctus	77.77	0.00e+00	1623.00
IUUC-Dor-030182	Dipodomys ordii	67.85	0.00e+00	951.00
IUUC-Ete-033152	Echinops telfairi	73.85	0.00e+00	1031.00
IUUC-Eca-033848	Equus caballus	71.92	3.00e-155	541.00
IUUC-Eeu-034535	Erinaceus europaeus	66.46	0.00e+00	831.00
IUUC-Fca-036363	Felis catus	86.20	0.00e+00	1412.00
IUUC-Gmo-039551	Gadus morhua	32.26	2.00e-35	143.00
IUUC-Gac-042429	Gasterosteus aculeatus	42.27	2.00e-92	332.00
IUUC-Ggo-045225	Gorilla gorilla	81.08	0.00e+00	1227.00
IUUC-Hsa-046739	Homo sapiens	80.65	0.00e+00	1149.00
IUUC-Itr-047862	Ictidomys tridecemlineatus	83.24	0.00e+00	880.00
IUUC-Lch-049722	Latimeria chalumnae	55.00	0.00e+00	1155.00
IUUC-Loc-052665	Lepisosteus oculatus	53.49	0.00e+00	1110.00
IUUC-Laf-054050	Loxodonta africana	76.42	0.00e+00	958.00
IUUC-Meu-056792	Macropus eugenii	63.64	0.00e+00	634.00
IUUC-Mmr-060714	Microcebus murinus	82.75	0.00e+00	888.00
IUUC-Mdo-062938	Monodelphis domestica	63.88	0.00e+00	873.00
IUUC-Mmu-063645	Mus musculus	74.72	0.00e+00	1080.00
IUUC-Mpu-066015	Mustela putorius furo	79.83	0.00e+00	1706.00
IUUC-Mlu-068140	Myotis lucifugus	81.97	0.00e+00	1091.00
IUUC-Nle-069533	Nomascus leucogenys	79.85	0.00e+00	1101.00
IUUC-Opr-070439	Ochotona princeps	60.74	0.00e+00	846.00
IUUC-Ont-072106	Oreochromis niloticus	28.28	4.00e-81	296.00
IUUC-Oan-073400	Ornithorhynchus anatinus	54.94	2.00e-97	348.00
IUUC-Ocu-074202	Oryctolagus cuniculus	81.23	0.00e+00	953.00
IUUC-Ola-086882	Oryzias latipes	41.70	1.00e-98	353.00
IUUC-Oga-087999	Otolemur garnettii	71.89	0.00e+00	1184.00
IUUC-Ptr-090859	Pan troglodytes	81.08	0.00e+00	1112.00
IUUC-Pan-092049	Papio anubis	83.60	0.00e+00	764.00
IUUC-Psi-093625	Pelodiscus sinensis	61.69	0.00e+00	874.00
IUUC-Pma-094599	Petromyzon marinus	30.20	8.00e-57	214.00
IUUC-Pfo-096408	Poecilia formosa	25.65	2.00e-46	180.00
IUUC-Pab-098444	Pongo abelii	87.56	0.00e+00	825.00
IUUC-Pca-100464	Procavia capensis	70.99	0.00e+00	664.00
IUUC-Pva-102863	Pteropus vampyrus	81.37	0.00e+00	1175.00
IUUC-Rno-105493	Rattus norvegicus	71.95	0.00e+00	1004.00
IUUC-Sha-107206	Sarcophilus harrisii	60.45	0.00e+00	811.00
IUUC-Smo-109247	Selaginella moellendorffii	23.96	9.00e-40	159.00
IUUC-Sar-113119	Sorex araneus	62.68	0.00e+00	731.00
IUUC-Ssc-116181	Sus scrofa	89.75	0.00e+00	1483.00
IUUC-Tru-118700	Takifugu rubripes	40.61	2.00e-87	315.00
IUUC-Tsy-119608	Tarsius syrichta	68.24	0.00e+00	930.00
IUUC-Tni-120461	Tetraodon nigroviridis	40.88	3.00e-88	318.00
IUUC-Tbe-127509	Tupaia belangeri	69.99	0.00e+00	949.00
IUUC-Ttr-128571	Tursiops truncatus	64.44	0.00e+00	846.00
IUUC-Vpa-130340	Vicugna pacos	81.86	0.00e+00	1185.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence