iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-005053

Ensembl Protein ID

ENSACAP00000002673.3

UniProt Accession

G1KB50; G1KB50_ANOCA

Protein Name

Uncharacterized protein

Gene Name

TLE1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000002262.3	ENSACAT00000002740.3	ENSACAP00000002673.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.90e-22	77.8	624	662

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t++ WDlr+g++l+
   Q: 624  GHTDGASCIDIsNDgTKLWTGGLDNTVRSWDLREGRQLQ 662
           8***********999*********************998 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MFPQSRHPTP HQAAGQSFKF TIPESLDRIK EEFQFLQAQY HSLKLECEKL ASEKTEMQRH 60
YVMYYEMSYG LNIEMHKQTE IAKRLNTICA QVIPFLSQEH QQQVAQAVER AKQVTMAELN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCTCAGCCT CGAAAGAAGA GTCCGGGAGA AGGGGCGGTG TTTGCTTGCC GAAGCGGCTT 60
CTCATTGGCT TTTCGTCACA GCCCCACGTT GGTTTCCGAG GATCCTATTG GTTCCCATCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0001106--F:RNA polymerase II transcription corepressor activity
GO:2000811--P:negative regulation of anoikis
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0010628--P:positive regulation of gene expression

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001746	Ailuropoda melanoleuca	91.72	0.00e+00	1234.00
IUUC-Apl-003594	Anas platyrhynchos	93.39	0.00e+00	1241.00
IUUC-Bta-013380	Bos taurus	87.71	0.00e+00	1136.00
IUUC-Cja-019135	Callithrix jacchus	95.77	0.00e+00	1283.00
IUUC-Cfa-020611	Canis familiaris	95.58	0.00e+00	1167.00
IUUC-Cpo-022495	Cavia porcellus	95.13	0.00e+00	1280.00
IUUC-Csa-024056	Chlorocebus sabaeus	95.64	0.00e+00	1297.00
IUUC-Dno-029011	Dasypus novemcinctus	95.52	0.00e+00	1282.00
IUUC-Ete-032533	Echinops telfairi	84.23	0.00e+00	1169.00
IUUC-Eca-033351	Equus caballus	96.03	0.00e+00	1286.00
IUUC-Eeu-034666	Erinaceus europaeus	97.23	0.00e+00	1062.00
IUUC-Fal-036696	Ficedula albicollis	96.82	0.00e+00	1256.00
IUUC-Gmo-038805	Gadus morhua	81.89	0.00e+00	1201.00
IUUC-Gga-041113	Gallus gallus	96.41	0.00e+00	1352.00
IUUC-Gac-041999	Gasterosteus aculeatus	81.62	0.00e+00	1198.00
IUUC-Ggo-045164	Gorilla gorilla	95.77	0.00e+00	1299.00
IUUC-Hsa-047011	Homo sapiens	95.77	0.00e+00	1299.00
IUUC-Itr-048040	Ictidomys tridecemlineatus	94.81	0.00e+00	1252.00
IUUC-Lch-050437	Latimeria chalumnae	93.83	0.00e+00	1115.00
IUUC-Loc-052819	Lepisosteus oculatus	93.47	0.00e+00	1235.00
IUUC-Laf-053862	Loxodonta africana	97.31	0.00e+00	1263.00
IUUC-Mcc-055735	Macaca mulatta	91.77	0.00e+00	1283.00
IUUC-Mmr-061207	Microcebus murinus	96.67	0.00e+00	1254.00
IUUC-Mdo-062493	Monodelphis domestica	96.67	0.00e+00	1344.00
IUUC-Mmu-063795	Mus musculus	94.88	0.00e+00	1255.00
IUUC-Mpu-065819	Mustela putorius furo	95.52	0.00e+00	1310.00
IUUC-Mlu-067047	Myotis lucifugus	95.90	0.00e+00	1268.00
IUUC-Nle-069684	Nomascus leucogenys	95.64	0.00e+00	1292.00
IUUC-Opr-071172	Ochotona princeps	94.74	0.00e+00	1262.00
IUUC-Ont-072102	Oreochromis niloticus	81.02	0.00e+00	1193.00
IUUC-Ocu-074592	Oryctolagus cuniculus	92.70	0.00e+00	1288.00
IUUC-Ola-087267	Oryzias latipes	78.45	0.00e+00	1105.00
IUUC-Oga-088629	Otolemur garnettii	97.31	0.00e+00	1258.00
IUUC-Oar-089551	Ovis aries	95.01	0.00e+00	1268.00
IUUC-Ptr-091207	Pan troglodytes	95.38	0.00e+00	1293.00
IUUC-Pan-091822	Papio anubis	91.77	0.00e+00	1283.00
IUUC-Psi-093594	Pelodiscus sinensis	97.80	0.00e+00	1287.00
IUUC-Pfo-096239	Poecilia formosa	81.41	0.00e+00	1204.00
IUUC-Pab-097687	Pongo abelii	95.73	0.00e+00	1280.00
IUUC-Pva-102355	Pteropus vampyrus	92.44	0.00e+00	1180.00
IUUC-Rno-106027	Rattus norvegicus	93.61	0.00e+00	1292.00
IUUC-Sha-107419	Sarcophilus harrisii	92.04	0.00e+00	1270.00
IUUC-Sar-113585	Sorex araneus	86.02	0.00e+00	710.00
IUUC-Ssc-116151	Sus scrofa	95.90	0.00e+00	1286.00
IUUC-Tgu-117387	Taeniopygia guttata	96.41	0.00e+00	1330.00
IUUC-Tsy-119342	Tarsius syrichta	88.32	0.00e+00	998.00
IUUC-Tbe-127881	Tupaia belangeri	93.21	0.00e+00	1267.00
IUUC-Xtr-131792	Xenopus tropicalis	89.68	0.00e+00	1239.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence