iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-073615

Ensembl Protein ID

ENSOANP00000007286.2

UniProt Accession

F7DM48; F7DM48_ORNAN

Protein Name

Uncharacterized protein

Gene Name

KIF21B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000004596.2	ENSOANT00000007288.2	ENSOANP00000007286.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-32	110.3	1449	1478
UBD/Beta-Prp	1.30e-41	143.0	1317	1518

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H+d+v++laf ++ ++l+s+++ g+ikvW+
   Q: 1449 HKDWVCALAFvPGrPMLLSACRGGVIKVWN 1478
           ***********999***************9 PP

UBD/Beta-Prp

   S: 52   eaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp...sgdklvsGshdrtirvwdletgqclee.... 131
           e++++++ +sp+g + + +++ + +++w+ls +++v +l+gh   v++l++++     d +v+Gs+d ++++++l +g   +     
   Q: 1317 EQQINQIALSPSG-TTLYAASGNSVRIWELSRFQPVGKLTGHIGPVMCLTVNRtpsHHDLVVTGSKDHYVKMFELAEGVSGNVgpth 1402
           678999******9.89999999******************************988555*******************9999889999 PP
   S: 132  .tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrt 217
            ++ +h + + c+++++  nll+sGs D+ ++ Wdl++++l+++   +h+d v  l+f + ++ l+s+ + g +k+w+  + + v +
   Q: 1403 nFEPPHYDGIECLAIQG--NLLFSGSRDNGIKKWDLEQQELMQQIPNAHKDWVCALAFVPGRPMLLSACRGGVIKVWNGDNFTPVGE 1487
           9999***********99..**************************999*************************************** PP
   S: 218  lnghtdnvksvrfspnderlvsgssDgsiriWd 250
            +gh+++++ + +   + ++ ++ssD  +++W 
   Q: 1488 IKGHDSPINAICTN--SRHIFTASSDCRVKLWS 1518
           *********77777..****************6 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MGTGFDVSTA EDEHGIIPRA IAHLFGGIEE RKRRAQEQGL VGPEFKVSAQ FLELYNEEIL 60
DLFDSTRDPD SRHRKSNIKI HEDASGGIYT TGVTSRLIGS QEELIQCLKQ GALSRTTAST 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTAAGCTCT AGCTGTGACC AGAAGGGCCC CTGTGACCAC CTGCACTCTC CCGAGGGCAG 60
ACCGGGGCCG GGAAGACCTA CACAATGGGC ACAGGCTTTG ACGTGAGCAC GGCAGAGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005871--C:kinesin complex
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001279	Ailuropoda melanoleuca	88.24	0.00e+00	2468.00
IUUC-Apl-003204	Anas platyrhynchos	74.88	0.00e+00	1417.00
IUUC-Aca-004506	Anolis carolinensis	82.66	0.00e+00	1631.00
IUUC-Ame-011515	Astyanax mexicanus	75.86	0.00e+00	1457.00
IUUC-Bta-013185	Bos taurus	73.25	0.00e+00	1184.00
IUUC-Cja-018844	Callithrix jacchus	86.19	0.00e+00	2459.00
IUUC-Cfa-021187	Canis familiaris	88.67	0.00e+00	2503.00
IUUC-Cpo-022444	Cavia porcellus	88.57	0.00e+00	2512.00
IUUC-Csa-023852	Chlorocebus sabaeus	89.13	0.00e+00	2528.00
IUUC-Cin-025160	Ciona intestinalis	44.65	8.00e-83	300.00
IUUC-Dre-027839	Danio rerio	74.19	0.00e+00	1429.00
IUUC-Dno-030058	Dasypus novemcinctus	86.77	0.00e+00	2461.00
IUUC-Dor-030673	Dipodomys ordii	87.81	0.00e+00	2462.00
IUUC-Eca-033885	Equus caballus	87.55	0.00e+00	2457.00
IUUC-Eeu-035338	Erinaceus europaeus	75.17	0.00e+00	1880.00
IUUC-Fca-035388	Felis catus	89.00	0.00e+00	2533.00
IUUC-Fal-037044	Ficedula albicollis	84.64	0.00e+00	2490.00
IUUC-Gmo-039034	Gadus morhua	68.33	0.00e+00	1264.00
IUUC-Gac-041328	Gasterosteus aculeatus	72.39	0.00e+00	2131.00
IUUC-Ggo-045392	Gorilla gorilla	88.60	0.00e+00	2511.00
IUUC-Hsa-046713	Homo sapiens	89.13	0.00e+00	2526.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	90.51	0.00e+00	1580.00
IUUC-Loc-052703	Lepisosteus oculatus	78.39	0.00e+00	2286.00
IUUC-Laf-054193	Loxodonta africana	79.05	0.00e+00	2185.00
IUUC-Mcc-055484	Macaca mulatta	88.02	0.00e+00	2508.00
IUUC-Meu-056278	Macropus eugenii	85.37	0.00e+00	1188.00
IUUC-Mga-059816	Meleagris gallopavo	83.46	0.00e+00	2377.00
IUUC-Mmr-061071	Microcebus murinus	87.30	0.00e+00	2465.00
IUUC-Mdo-062845	Monodelphis domestica	87.54	0.00e+00	2547.00
IUUC-Mmu-063967	Mus musculus	89.20	0.00e+00	2468.00
IUUC-Mpu-066448	Mustela putorius furo	87.77	0.00e+00	2504.00
IUUC-Nle-070037	Nomascus leucogenys	91.19	0.00e+00	1755.00
IUUC-Opr-070325	Ochotona princeps	84.56	0.00e+00	2340.00
IUUC-Ont-071851	Oreochromis niloticus	73.06	0.00e+00	2123.00
IUUC-Ocu-073855	Oryctolagus cuniculus	89.20	0.00e+00	2488.00
IUUC-Ola-086703	Oryzias latipes	74.54	0.00e+00	1476.00
IUUC-Oga-088171	Otolemur garnettii	87.58	0.00e+00	2463.00
IUUC-Oar-089693	Ovis aries	74.70	0.00e+00	1172.00
IUUC-Ptr-090535	Pan troglodytes	90.29	0.00e+00	1713.00
IUUC-Pan-091917	Papio anubis	88.73	0.00e+00	2304.00
IUUC-Psi-093752	Pelodiscus sinensis	79.16	0.00e+00	1407.00
IUUC-Pfo-096827	Poecilia formosa	70.12	0.00e+00	1353.00
IUUC-Pab-098441	Pongo abelii	89.51	0.00e+00	2537.00
IUUC-Pca-100781	Procavia capensis	89.60	0.00e+00	758.00
IUUC-Pva-103099	Pteropus vampyrus	87.24	0.00e+00	1289.00
IUUC-Rno-105872	Rattus norvegicus	87.78	0.00e+00	2506.00
IUUC-Sha-107097	Sarcophilus harrisii	88.88	0.00e+00	2422.00
IUUC-Ssc-115638	Sus scrofa	88.13	0.00e+00	2175.00
IUUC-Tgu-116504	Taeniopygia guttata	82.29	0.00e+00	1500.00
IUUC-Tru-118242	Takifugu rubripes	75.22	0.00e+00	1488.00
IUUC-Ttr-128824	Tursiops truncatus	85.15	0.00e+00	2147.00
IUUC-Xtr-131798	Xenopus tropicalis	65.87	0.00e+00	1192.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence