iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098165

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01293118

Gene Name

MARCH8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000002230.2	ENSPPYT00000002683.2	ENSPPYP00000002603.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	98.63	4.00e-152	534.00	IUUC-Hsa-045936
E3 activity/RING/RING	86.25	2.00e-140	495.00	IUUC-Mmu-063373

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pongo abelii

Protein Sequence
(Fasta)

MSMPLHQISA IPSQDAASAR VYRSKTKEKE REEQNEKTLG HSMSHSSNIS KAGSPPSASA 60
PAPVSSFSRT SITPSSQDIC RICHCEGDDE SPLITPCHCT GSLHFVHQAC LQQWIKSSDT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NTTCTAGGCC GGGCGGCCCC CGGGTCCCAG GTTGATTTCC TTTCCCTGAC 60
GGGCTGTGAG ACGTTGGCCC GTCAGCCGTC GTCTTTGGCC TGAGTTTGCA CATCTGTAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR033275--MARCH-like
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51292--ZF_RING_CH

Pfam

PF12906--RINGv

SMART

SM00744--RINGv

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0002495--P:antigen processing and presentation of peptide antigen via MHC class II
GO:0045347--P:negative regulation of MHC class II biosynthetic process

KEGG

pon:100459058

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001621	Ailuropoda melanoleuca	74.55	2.00e-97	348.00
IUUC-Aca-004316	Anolis carolinensis	71.21	3.00e-101	361.00
IUUC-Bta-013415	Bos taurus	91.07	4.00e-153	533.00
IUUC-Cel-018329	Caenorhabditis elegans	45.76	4.00e-10	59.30
IUUC-Cja-019593	Callithrix jacchus	74.11	4.00e-97	347.00
IUUC-Cfa-020901	Canis familiaris	89.00	1.00e-146	511.00
IUUC-Cpo-021679	Cavia porcellus	89.53	5.00e-133	466.00
IUUC-Csa-023704	Chlorocebus sabaeus	97.94	1.00e-153	535.00
IUUC-Cho-024995	Choloepus hoffmanni	87.60	9.00e-60	221.00
IUUC-Cin-025566	Ciona intestinalis	68.00	2.00e-15	75.50
IUUC-Dre-027670	Danio rerio	77.66	3.00e-123	434.00
IUUC-Dno-028902	Dasypus novemcinctus	88.66	7.00e-147	512.00
IUUC-Dor-030770	Dipodomys ordii	61.67	6.00e-63	234.00
IUUC-Dme-031717	Drosophila melanogaster	56.63	5.00e-60	225.00
IUUC-Eca-033918	Equus caballus	91.56	2.00e-123	434.00
IUUC-Eeu-034876	Erinaceus europaeus	80.28	2.00e-99	355.00
IUUC-Fca-035915	Felis catus	74.55	8.00e-97	346.00
IUUC-Gmo-039585	Gadus morhua	76.03	1.00e-121	429.00
IUUC-Gga-040516	Gallus gallus	86.25	1.00e-142	498.00
IUUC-Gac-041554	Gasterosteus aculeatus	76.71	6.00e-123	433.00
IUUC-Ggo-045247	Gorilla gorilla	73.66	1.00e-96	345.00
IUUC-Hsa-045936	Homo sapiens	98.63	2.00e-153	535.00
IUUC-Lch-049853	Latimeria chalumnae	81.10	5.00e-134	469.00
IUUC-Loc-052142	Lepisosteus oculatus	76.35	1.00e-121	429.00
IUUC-Laf-054075	Loxodonta africana	91.11	3.00e-123	433.00
IUUC-Mcc-054834	Macaca mulatta	98.28	5.00e-154	536.00
IUUC-Meu-056594	Macropus eugenii	59.50	3.00e-33	134.00
IUUC-Mga-059662	Meleagris gallopavo	79.81	2.00e-97	348.00
IUUC-Mmr-061603	Microcebus murinus	94.50	1.00e-155	541.00
IUUC-Mdo-062578	Monodelphis domestica	88.01	1.00e-144	505.00
IUUC-Mmu-063373	Mus musculus	88.66	2.00e-145	508.00
IUUC-Nle-069774	Nomascus leucogenys	98.63	6.00e-154	536.00
IUUC-Oan-072984	Ornithorhynchus anatinus	71.60	6.00e-102	363.00
IUUC-Ocu-074342	Oryctolagus cuniculus	79.73	6.00e-124	436.00
IUUC-Obr-076417	Oryza brachyantha	28.08	4.00e-10	58.20
IUUC-Ola-086344	Oryzias latipes	77.48	3.00e-112	397.00
IUUC-Oga-088670	Otolemur garnettii	90.80	8.00e-129	452.00
IUUC-Ptr-090574	Pan troglodytes	97.59	5.00e-153	533.00
IUUC-Pan-092925	Papio anubis	97.25	5.00e-153	533.00
IUUC-Psi-093085	Pelodiscus sinensis	86.25	2.00e-133	468.00
IUUC-Pma-094229	Petromyzon marinus	57.33	3.00e-71	260.00
IUUC-Pfo-097524	Poecilia formosa	65.01	9.00e-116	409.00
IUUC-Pca-100362	Procavia capensis	52.68	1.00e-62	233.00
IUUC-Rno-105837	Rattus norvegicus	88.66	2.00e-145	508.00
IUUC-Sha-107014	Sarcophilus harrisii	88.94	2.00e-119	422.00
IUUC-Sar-113258	Sorex araneus	79.29	9.00e-93	332.00
IUUC-Tgu-116539	Taeniopygia guttata	71.21	4.00e-102	363.00
IUUC-Tru-117951	Takifugu rubripes	75.86	4.00e-103	367.00
IUUC-Tsy-119324	Tarsius syrichta	74.11	1.00e-96	345.00
IUUC-Tni-120496	Tetraodon nigroviridis	75.88	1.00e-106	379.00
IUUC-Tbe-127567	Tupaia belangeri	86.11	5.00e-95	340.00
IUUC-Ttr-129098	Tursiops truncatus	73.33	2.00e-95	342.00
IUUC-Vpa-130287	Vicugna pacos	53.57	1.00e-61	229.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence