iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054060

UUCD1 version

UUC-LoA-00772

Ensembl Protein ID

ENSLAFP00000021530.1

UniProt Accession

G3U122; G3U122_LOXAF

Protein Name

Uncharacterized protein

Gene Name

WDR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000007080.3	ENSLAFT00000033286.1	ENSLAFP00000021530.1
ENSLAFG00000007080.3	ENSLAFT00000007082.3	ENSLAFP00000005953.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.10e-35	117.9	264	294
UBD/Beta-Prp	5.70e-56	190.2	87	377

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           H ++++++++ +d t+l+s+s+D+t k+WD+
   Q: 264  HDGGIYAISWsPDsTHLLSASGDKTSKIWDV 294
           99*********999****************7 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl..sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlkg 92
           +h +++ + k++p++ ++a+g  +g++++wd+t++  l ++  +   ++++++ + +d+k ++ ++e   ++  v+  ++g+ v  ++g
   Q: 87   EHAHQVVVAKYAPSGFYVASGDVSGKLRIWDTTQKEHLLKYeyQPFAGKIKDIAWTEDSKRIAVVGEGreKFGAVFLWDSGSSVGEITG 175
           556666678*************************998777742334567***********99999999887777777789********* PP
   S: 93   hedsvlslsfspsg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tgg 178
           h++ + s+++ +++ ++l++Gs+d+ +  ++ +  +    t   h+++vncv+++pdgn ++++s+D+++ ++d ktg+ + tl  +++
   Q: 176  HNKVINSVDIKQTRpYRLATGSDDNCAAFFEGPPFKFKF-TIGDHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVSTLggSKA 263
           ************999*****************9999998.99********************************************888 PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvks.vrfspnderlvsgssDgsiriWdlrs.gdllktlqlhns 265
           h++ +y +s+++++++l+s+s d+t k+wd+  +++v t++  ++   + +  + ++++l+s s  g i+  d+ + +++l+++++h +
   Q: 264  HDGGIYAISWSPDSTHLLSASGDKTSKIWDVNVNSIVSTFTMGSNVLDQqLGCLWQKDHLLSISLSGYINYLDKNNpSKPLRVIKGHSK 352
           ***************************************99877655541444478999999**9******987653678888888888 PP
   S: 266  svisvavlsfg.dnvlvlgsedskv 289
           s+ + +v++ g ++++++gse +++
   Q: 353  SIQCLTVHKNGgKSYIYSGSEAGQA 377
           8888888766668899999997766 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

DRPQPARHAR RRLPARPRPG LGESELQRVA RMPFEIKKVF ASLPQVERGV SKIIGGDPKG 60
NNFLYTNGKC VILRNIDNPA VADIYTEHAH QVVVAKYAPS GFYVASGDVS GKLRIWDTTQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACCGCCCCC AGCCCGCCCG GCACGCCCGG CGCCGCCTTC CGGCCCGTCC CCGGCCTGGG 60
CTTGGCGAGT CTGAGTTGCA GCGCGGTCCG TGCTGACCGG CCCGGGGCTC TCGGCGAGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011043--Gal_Oxase/kelch_b-propeller
IPR011045--N2O_reductase_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0043209--C:myelin sheath
GO:0030043--P:actin filament fragmentation
GO:0043297--P:apical junction assembly
GO:0030865--P:cortical cytoskeleton organization
GO:0042247--P:establishment of planar polarity of follicular epithelium
GO:0045199--P:maintenance of epithelial cell apical/basal polarity
GO:0002446--P:neutrophil mediated immunity
GO:1990266--P:neutrophil migration
GO:0030220--P:platelet formation
GO:0030836--P:positive regulation of actin filament depolymerization
GO:0008360--P:regulation of cell shape
GO:0060307--P:regulation of ventricular cardiac muscle cell membrane repolarization
GO:0045214--P:sarcomere organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000457	Aegilops tauschii	34.27	3.00e-78	285.00
IUUC-Aml-002368	Ailuropoda melanoleuca	93.18	0.00e+00	1132.00
IUUC-Atr-003160	Amborella trichopoda	37.11	2.00e-114	406.00
IUUC-Apl-004012	Anas platyrhynchos	86.92	0.00e+00	1069.00
IUUC-Aca-004707	Anolis carolinensis	80.56	0.00e+00	1013.00
IUUC-Aly-006465	Arabidopsis lyrata	37.32	3.00e-111	395.00
IUUC-Ath-006740	Arabidopsis thaliana	36.50	8.00e-110	390.00
IUUC-Ago-007920	Ashbya gossypii	28.09	5.00e-74	271.00
IUUC-Acl-008262	Aspergillus clavatus	37.58	9.00e-106	377.00
IUUC-Afl-008471	Aspergillus flavus	33.67	1.00e-86	313.00
IUUC-Afu-008989	Aspergillus fumigatus	38.92	1.00e-94	340.00
IUUC-Ani-009167	Aspergillus nidulans	38.03	3.00e-114	405.00
IUUC-Ang-009595	Aspergillus niger	38.23	1.00e-100	360.00
IUUC-Aor-009908	Aspergillus oryzae	36.47	5.00e-100	358.00
IUUC-Ate-010580	Aspergillus terreus	38.08	2.00e-107	384.00
IUUC-Ame-011269	Astyanax mexicanus	57.50	2.00e-124	439.00
IUUC-Bgr-011996	Blumeria graminis	34.47	5.00e-104	371.00
IUUC-Bta-013278	Bos taurus	92.74	0.00e+00	1164.00
IUUC-Bci-013925	Botrytis cinerea	34.91	6.00e-103	368.00
IUUC-Bdi-014659	Brachypodium distachyon	35.03	1.00e-101	363.00
IUUC-Bol-016043	Brassica oleracea	35.02	1.00e-104	373.00
IUUC-Bra-017139	Brassica rapa	36.35	2.00e-109	389.00
IUUC-Cel-018417	Caenorhabditis elegans	40.26	3.00e-121	428.00
IUUC-Cja-019952	Callithrix jacchus	92.43	0.00e+00	1116.00
IUUC-Cfa-020225	Canis familiaris	93.07	0.00e+00	1142.00
IUUC-Cpo-021900	Cavia porcellus	92.01	0.00e+00	1120.00
IUUC-Csa-023028	Chlorocebus sabaeus	93.40	0.00e+00	1119.00
IUUC-Cho-025030	Choloepus hoffmanni	67.95	0.00e+00	739.00
IUUC-Cin-025152	Ciona intestinalis	55.77	3.00e-83	301.00
IUUC-Csv-025986	Ciona savignyi	36.77	3.00e-88	318.00
IUUC-Cgl-026597	Colletotrichum gloeosporioides	38.17	3.00e-109	389.00
IUUC-Cne-026814	Cryptococcus neoformans	34.14	2.00e-94	340.00
IUUC-Dre-027498	Danio rerio	80.00	4.00e-96	343.00
IUUC-Dno-029383	Dasypus novemcinctus	92.24	0.00e+00	1100.00
IUUC-Dor-030633	Dipodomys ordii	91.15	0.00e+00	1057.00
IUUC-Dse-031526	Dothistroma septosporum	38.19	5.00e-114	404.00
IUUC-Dme-031597	Drosophila melanogaster	47.19	3.00e-165	575.00
IUUC-Ete-032780	Echinops telfairi	83.14	0.00e+00	1018.00
IUUC-Eca-034306	Equus caballus	91.76	0.00e+00	1116.00
IUUC-Eeu-034531	Erinaceus europaeus	71.74	2.00e-130	458.00
IUUC-Fca-036301	Felis catus	93.51	0.00e+00	1159.00
IUUC-Fal-037361	Ficedula albicollis	86.28	0.00e+00	1100.00
IUUC-Fox-037924	Fusarium oxysporum	34.47	4.00e-98	352.00
IUUC-Fso-038199	Fusarium solani	33.60	7.00e-93	334.00
IUUC-Gmo-039238	Gadus morhua	70.35	0.00e+00	857.00
IUUC-Ggr-039830	Gaeumannomyces graminis	35.49	3.00e-93	336.00
IUUC-Gga-040235	Gallus gallus	86.99	0.00e+00	1073.00
IUUC-Gac-042363	Gasterosteus aculeatus	70.84	0.00e+00	896.00
IUUC-Gma-044189	Glycine max	37.17	2.00e-112	399.00
IUUC-Ggo-044632	Gorilla gorilla	91.19	0.00e+00	1099.00
IUUC-Hsa-045792	Homo sapiens	92.74	0.00e+00	1139.00
IUUC-Hvu-047517	Hordeum vulgare	34.54	8.00e-105	374.00
IUUC-Itr-048076	Ictidomys tridecemlineatus	93.01	0.00e+00	1126.00
IUUC-Kpa-049183	Komagataella pastoris	32.68	2.00e-84	306.00
IUUC-Lch-050428	Latimeria chalumnae	74.51	0.00e+00	980.00
IUUC-Lpe-051306	Leersia perrieri	35.03	3.00e-106	379.00
IUUC-Loc-052096	Lepisosteus oculatus	69.90	0.00e+00	870.00
IUUC-Lma-053313	Leptosphaeria maculans	39.18	1.00e-112	402.00
IUUC-Mcc-055619	Macaca mulatta	92.01	0.00e+00	1105.00
IUUC-Meu-056689	Macropus eugenii	76.56	2.00e-178	618.00
IUUC-Mor-056940	Magnaporthe oryzae	34.58	5.00e-94	338.00
IUUC-Mpo-057557	Magnaporthe poae	30.13	1.00e-64	240.00
IUUC-Mtr-057922	Medicago truncatula	35.53	2.00e-109	389.00
IUUC-Mla-059103	Melampsora laricipopulina	33.57	1.00e-79	290.00
IUUC-Mga-060150	Meleagris gallopavo	86.92	0.00e+00	1062.00
IUUC-Mvi-060448	Microbotryum violaceum	31.32	1.00e-75	277.00
IUUC-Mmr-061226	Microcebus murinus	94.19	0.00e+00	1145.00
IUUC-Mdo-062674	Monodelphis domestica	89.44	0.00e+00	1104.00
IUUC-Mmu-064170	Mus musculus	92.74	0.00e+00	1135.00
IUUC-Mac-065124	Musa acuminata	37.99	1.00e-112	400.00
IUUC-Mpu-066001	Mustela putorius furo	89.19	0.00e+00	1117.00
IUUC-Mlu-067253	Myotis lucifugus	92.01	0.00e+00	1136.00
IUUC-Nfi-068550	Neosartorya fischeri	38.74	2.00e-109	389.00
IUUC-Ncr-068948	Neurospora crassa	36.98	6.00e-112	397.00
IUUC-Nle-070115	Nomascus leucogenys	88.98	0.00e+00	1034.00
IUUC-Opr-070254	Ochotona princeps	89.60	0.00e+00	1071.00
IUUC-Ont-071666	Oreochromis niloticus	73.93	0.00e+00	927.00
IUUC-Oan-073594	Ornithorhynchus anatinus	88.29	7.00e-154	536.00
IUUC-Ocu-074824	Oryctolagus cuniculus	90.26	0.00e+00	1084.00
IUUC-Oba-075010	Oryza barthii	35.80	1.00e-107	383.00
IUUC-Obr-076364	Oryza brachyantha	35.96	4.00e-108	385.00
IUUC-Ogl-077019	Oryza glaberrima	35.80	1.00e-107	383.00
IUUC-Ogu-078496	Oryza glumaepatula	35.80	1.00e-107	383.00
IUUC-Oin-080116	Oryza indica	35.96	4.00e-108	385.00
IUUC-Olo-080290	Oryza longistaminata	35.80	2.00e-107	383.00
IUUC-Ome-081969	Oryza meridionalis	35.80	1.00e-107	383.00
IUUC-Oni-082075	Oryza nivara	35.80	1.00e-107	383.00
IUUC-Opu-083959	Oryza punctata	35.53	2.00e-107	382.00
IUUC-Oru-084711	Oryza rufipogon	35.80	1.00e-107	383.00
IUUC-Osa-085958	Oryza sativa	35.96	4.00e-108	385.00
IUUC-Ola-086968	Oryzias latipes	73.64	0.00e+00	941.00
IUUC-Oga-089108	Otolemur garnettii	91.23	0.00e+00	1171.00
IUUC-Oar-089986	Ovis aries	87.38	0.00e+00	1071.00
IUUC-Ptr-091281	Pan troglodytes	93.00	0.00e+00	1130.00
IUUC-Pan-092585	Papio anubis	93.40	0.00e+00	1120.00
IUUC-Psi-093811	Pelodiscus sinensis	85.05	0.00e+00	1087.00
IUUC-Pma-094396	Petromyzon marinus	69.11	0.00e+00	885.00
IUUC-Pno-095086	Phaeosphaeria nodorum	36.86	2.00e-107	382.00
IUUC-Ppa-095876	Physcomitrella patens	35.68	3.00e-110	392.00
IUUC-Pfo-096973	Poecilia formosa	74.59	0.00e+00	969.00
IUUC-Pab-098391	Pongo abelii	93.07	0.00e+00	1117.00
IUUC-Pop-098850	Populus trichocarpa	36.56	7.00e-110	390.00
IUUC-Pca-100257	Procavia capensis	62.05	3.00e-90	326.00
IUUC-Ppe-101578	Prunus persica	37.44	2.00e-112	399.00
IUUC-Pva-102872	Pteropus vampyrus	87.44	0.00e+00	1101.00
IUUC-Pgr-103593	Puccinia graminis	32.61	7.00e-78	284.00
IUUC-Pte-104365	Pyrenophora teres	38.83	5.00e-111	395.00
IUUC-Pyt-104689	Pyrenophora triticirepentis	38.76	6.00e-114	404.00
IUUC-Rno-105737	Rattus norvegicus	93.40	0.00e+00	1172.00
IUUC-Sce-106383	Saccharomyces cerevisiae	28.96	2.00e-65	243.00
IUUC-Sha-107084	Sarcophilus harrisii	86.99	0.00e+00	969.00
IUUC-Sja-107688	Schizosaccharomyces japonicus	35.20	4.00e-109	388.00
IUUC-Spo-108309	Schizosaccharomyces pombe	33.50	6.00e-95	341.00
IUUC-Ssl-108408	Sclerotinia sclerotiorum	34.68	6.00e-102	364.00
IUUC-Smo-109255	Selaginella moellendorffii	34.96	1.00e-99	356.00
IUUC-Sit-109962	Setaria italica	36.39	2.00e-108	385.00
IUUC-Sly-110897	Solanum lycopersicum	37.54	6.00e-115	407.00
IUUC-Stu-111971	Solanum tuberosum	37.54	2.00e-114	405.00
IUUC-Sar-113415	Sorex araneus	71.59	5.00e-108	384.00
IUUC-Sbi-114857	Sorghum bicolor	36.39	9.00e-108	384.00
IUUC-Sre-114900	Sporisorium reilianum	32.95	4.00e-88	318.00
IUUC-Tgu-117256	Taeniopygia guttata	86.38	0.00e+00	1098.00
IUUC-Tru-117871	Takifugu rubripes	67.93	0.00e+00	865.00
IUUC-Tsy-119172	Tarsius syrichta	95.83	1.00e-137	483.00
IUUC-Tni-120339	Tetraodon nigroviridis	68.75	0.00e+00	894.00
IUUC-Tca-121609	Theobroma cacao	36.71	4.00e-110	392.00
IUUC-Tre-122076	Trichoderma reesei	34.43	4.00e-90	325.00
IUUC-Tvi-122528	Trichoderma virens	33.11	1.00e-91	330.00
IUUC-Tae-124549	Triticum aestivum	34.87	1.00e-105	376.00
IUUC-Tur-126845	Triticum urartu	34.23	2.00e-77	282.00
IUUC-Tme-127217	Tuber melanosporum	34.29	1.00e-101	363.00
IUUC-Tbe-127526	Tupaia belangeri	90.36	0.00e+00	1124.00
IUUC-Ttr-128898	Tursiops truncatus	86.46	0.00e+00	1077.00
IUUC-Uma-129631	Ustilago maydis	31.91	1.00e-91	330.00
IUUC-Vda-129732	Verticillium dahliae	34.82	1.00e-89	323.00
IUUC-Vvi-131217	Vitis vinifera	37.15	9.00e-112	397.00
IUUC-Xtr-132860	Xenopus tropicalis	72.61	0.00e+00	922.00
IUUC-Xma-133830	Xiphophorus maculatus	74.59	0.00e+00	970.00
IUUC-Yli-134335	Yarrowia lipolytica	33.39	1.00e-75	277.00
IUUC-Zma-135907	Zea mays	36.45	1.00e-108	387.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence