iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-041773

UUCD1 version

UUC-GaA-01166

Ensembl Protein ID

ENSGACP00000013077.1

UniProt Accession

G3P654; G3P654_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000009903.1	ENSGACT00000013102.1	ENSGACP00000013077.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.90e-214	712.2	452	930

Active Site

Position(s)	Description	Evidence
632	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkeln 85
           YD+Q++++G + qe l +++++lvGag++GcEllKn++++G+    g++ v+Dmdt+e+snlnrqFLfr++dv k K+++aa+a+k++n
   Q: 452  YDGQVAVFGTKLQEMLAKQRYFLVGAGAIGCELLKNFAMIGLasgdGEVIVTDMDTIEKSNLNRQFLFRPSDVTKMKSDTAAAAVKQMN 540
           ***************************************************************************************** PP
   S: 86   pdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqkti 171
           p+++++ h++++ +++e+++   Ff+ +d+V +aldn++ar++++r+c+++r+pl+esgtlG++G+v+v+i+ lte+ys+s+dpp+k+i
   Q: 541  PSIRITGHQNRVGPDTERVYdddFFESLDGVTNALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQDPPEKSI 629
           *******************9********************************************************************* PP
   S: 172  Pfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakt 248
           P+ctlk++pna+eht++wa            + ++++l  ++++ e++ kl  +++ e++++v ++l++  + ++++++++a+++++ +
   Q: 630  PICTLKNFPNAIEHTLQWArdefeglfkqppENAQQFL-SDPKFMERTLKLPGAQPVEVLEAVYKSLVTDCPHSWADCVAWARNHWQCQ 717
           ******************************99999999.567777777789************************************** PP
   S: 249  tinsikqllksfecdivtkskspfwv...................................................sfcsnaealqvp 286
           ++n+i+qll++f++d++t+s++pfw+                                                   ++++++ +    
   Q: 718  YSNNIRQLLHNFPPDQLTSSGAPFWSgpkrcphplefstsnelhmdyvvaganlfaqsygmpgstdragvikilqdvKVPPFTPRSG-V 805
           ***********************************9999999999999999999999999999999987777777763333333322.2 PP
   S: 287  ekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipa 368
           + +++d+e + ++++     l+ l+  l +  ++++ k + ++fekddd   ++d++ a +nlrae+++i+p  d+++ k iag+iipa
   Q: 806  KIHVSDQELQNSNSSvddcrLEELKVQLPS-PETSNFKLNAIDFEKDDDTnfHMDFIVASSNLRAENYDIPP-TDRHKSKLIAGKIIPA 892
           444555554444444556544444444444.456777789********************************.**************** PP
   S: 369  iattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           iatt+++v Gl+++E+iK+v g  k e +kn f+++a+
   Q: 893  IATTTSAVVGLVCLELIKIVRGhkKLESFKNGFMNLAL 930
           *********************999999******99875 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MSSSPLSKKR RLSGTETKTG SHCSSSNSVR TDLSHTPANG MAKNGNDAEI DEGLYSRQLY 60
VLGHEAMKRM QNSYVLISGM RGLGVEIAKN VILGGVKGVT VHDQGVAEWR DLSSQFYLRE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGAAACACT TTTCAGTTCC CCATCAGCAG CCGTGTTGAT TTGCCACATT GTTTTTTTAG 60
GTTTCTTGCT TAAATACAAG CCGATTTTAA TACTACAGAT CAGGCCGAGT AATATCGGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000456	Aegilops tauschii	44.17	0.00e+00	853.00
IUUC-Aml-001311	Ailuropoda melanoleuca	75.73	0.00e+00	1661.00
IUUC-Atr-002684	Amborella trichopoda	43.06	0.00e+00	853.00
IUUC-Aca-004620	Anolis carolinensis	76.63	0.00e+00	1657.00
IUUC-Aly-005515	Arabidopsis lyrata	42.79	0.00e+00	869.00
IUUC-Ath-006891	Arabidopsis thaliana	43.62	0.00e+00	880.00
IUUC-Ago-007873	Ashbya gossypii	51.53	0.00e+00	990.00
IUUC-Acl-008181	Aspergillus clavatus	53.03	0.00e+00	1022.00
IUUC-Afl-008455	Aspergillus flavus	52.23	0.00e+00	982.00
IUUC-Afu-009065	Aspergillus fumigatus	53.12	0.00e+00	1043.00
IUUC-Ani-009371	Aspergillus nidulans	51.74	0.00e+00	1001.00
IUUC-Ang-009737	Aspergillus niger	52.91	0.00e+00	1023.00
IUUC-Aor-010007	Aspergillus oryzae	52.23	0.00e+00	983.00
IUUC-Ate-010466	Aspergillus terreus	52.29	0.00e+00	1040.00
IUUC-Ame-010933	Astyanax mexicanus	85.73	0.00e+00	1809.00
IUUC-Bgr-012281	Blumeria graminis	51.27	0.00e+00	1011.00
IUUC-Bta-012767	Bos taurus	76.86	0.00e+00	1688.00
IUUC-Bci-013721	Botrytis cinerea	53.95	0.00e+00	1003.00
IUUC-Bdi-014335	Brachypodium distachyon	42.94	0.00e+00	853.00
IUUC-Bol-015665	Brassica oleracea	43.34	0.00e+00	865.00
IUUC-Bra-017252	Brassica rapa	42.64	0.00e+00	877.00
IUUC-Cel-018260	Caenorhabditis elegans	48.49	0.00e+00	934.00
IUUC-Cja-019152	Callithrix jacchus	75.73	0.00e+00	1667.00
IUUC-Cfa-020622	Canis familiaris	74.22	0.00e+00	1604.00
IUUC-Cpo-022526	Cavia porcellus	75.83	0.00e+00	1659.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	44.76	0.00e+00	825.00
IUUC-Csa-023780	Chlorocebus sabaeus	76.30	0.00e+00	1679.00
IUUC-Cin-025790	Ciona intestinalis	61.67	0.00e+00	1291.00
IUUC-Csv-026084	Ciona savignyi	59.00	0.00e+00	1276.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	52.88	0.00e+00	1056.00
IUUC-Cne-026960	Cryptococcus neoformans	54.81	0.00e+00	1069.00
IUUC-Cme-027290	Cyanidioschyzon merolae	44.29	0.00e+00	805.00
IUUC-Dre-028149	Danio rerio	85.26	0.00e+00	1829.00
IUUC-Dno-028884	Dasypus novemcinctus	76.02	0.00e+00	1674.00
IUUC-Dor-030229	Dipodomys ordii	72.99	0.00e+00	1588.00
IUUC-Dse-031524	Dothistroma septosporum	50.98	0.00e+00	1000.00
IUUC-Dme-032045	Drosophila melanogaster	58.88	0.00e+00	1254.00
IUUC-Ete-032544	Echinops telfairi	76.94	0.00e+00	658.00
IUUC-Eca-033330	Equus caballus	76.02	0.00e+00	1674.00
IUUC-Eeu-034717	Erinaceus europaeus	41.40	1.00e-157	550.00
IUUC-Fca-036255	Felis catus	76.11	0.00e+00	1667.00
IUUC-Fal-037445	Ficedula albicollis	47.07	0.00e+00	827.00
IUUC-Fox-038007	Fusarium oxysporum	53.40	5.00e-161	561.00
IUUC-Fso-038339	Fusarium solani	52.83	0.00e+00	1012.00
IUUC-Gmo-039338	Gadus morhua	84.98	0.00e+00	1783.00
IUUC-Ggr-039823	Gaeumannomyces graminis	51.95	0.00e+00	1055.00
IUUC-Gga-040365	Gallus gallus	44.89	0.00e+00	759.00
IUUC-Gma-043198	Glycine max	43.18	0.00e+00	835.00
IUUC-Ggo-045336	Gorilla gorilla	76.11	0.00e+00	1663.00
IUUC-Hsa-045982	Homo sapiens	76.02	0.00e+00	1658.00
IUUC-Hvu-047418	Hordeum vulgare	44.05	0.00e+00	838.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	76.39	0.00e+00	1678.00
IUUC-Kpa-049112	Komagataella pastoris	50.15	0.00e+00	967.00
IUUC-Lch-050371	Latimeria chalumnae	81.21	0.00e+00	1759.00
IUUC-Lpe-051299	Leersia perrieri	43.02	0.00e+00	833.00
IUUC-Loc-052936	Lepisosteus oculatus	84.04	0.00e+00	1804.00
IUUC-Lma-053315	Leptosphaeria maculans	51.99	0.00e+00	1052.00
IUUC-Laf-053948	Loxodonta africana	74.22	0.00e+00	1614.00
IUUC-Mcc-055843	Macaca mulatta	76.39	0.00e+00	1681.00
IUUC-Meu-056258	Macropus eugenii	75.17	0.00e+00	1639.00
IUUC-Mor-057269	Magnaporthe oryzae	52.48	0.00e+00	1041.00
IUUC-Mpo-057435	Magnaporthe poae	52.29	0.00e+00	1035.00
IUUC-Mtr-058572	Medicago truncatula	43.10	0.00e+00	812.00
IUUC-Mla-059176	Melampsora laricipopulina	54.73	0.00e+00	1061.00
IUUC-Mvi-060437	Microbotryum violaceum	52.45	0.00e+00	1018.00
IUUC-Mmr-061405	Microcebus murinus	74.03	0.00e+00	1614.00
IUUC-Mdo-062032	Monodelphis domestica	74.25	0.00e+00	1624.00
IUUC-Mmu-063280	Mus musculus	75.64	0.00e+00	1650.00
IUUC-Mac-065505	Musa acuminata	44.75	0.00e+00	850.00
IUUC-Mpu-066409	Mustela putorius furo	76.49	0.00e+00	1685.00
IUUC-Mlu-067217	Myotis lucifugus	75.64	0.00e+00	1654.00
IUUC-Nfi-068407	Neosartorya fischeri	52.93	0.00e+00	1021.00
IUUC-Ncr-068698	Neurospora crassa	52.48	0.00e+00	1050.00
IUUC-Nle-070072	Nomascus leucogenys	72.00	0.00e+00	1551.00
IUUC-Opr-070715	Ochotona princeps	40.22	0.00e+00	703.00
IUUC-Ont-071671	Oreochromis niloticus	89.85	0.00e+00	1904.00
IUUC-Ocu-074544	Oryctolagus cuniculus	77.05	0.00e+00	1694.00
IUUC-Oba-075120	Oryza barthii	43.16	0.00e+00	828.00
IUUC-Obr-076557	Oryza brachyantha	44.48	0.00e+00	820.00
IUUC-Ogl-077887	Oryza glaberrima	43.25	0.00e+00	830.00
IUUC-Ogu-078305	Oryza glumaepatula	43.27	0.00e+00	839.00
IUUC-Oin-079370	Oryza indica	42.37	0.00e+00	815.00
IUUC-Olo-081089	Oryza longistaminata	42.98	0.00e+00	835.00
IUUC-Ome-081942	Oryza meridionalis	43.09	0.00e+00	832.00
IUUC-Oni-082365	Oryza nivara	43.25	0.00e+00	831.00
IUUC-Opu-083977	Oryza punctata	43.73	0.00e+00	841.00
IUUC-Oru-084469	Oryza rufipogon	43.17	0.00e+00	839.00
IUUC-Osa-085949	Oryza sativa	43.25	0.00e+00	838.00
IUUC-Ola-087002	Oryzias latipes	88.79	0.00e+00	1890.00
IUUC-Olu-087687	Ostreococcus lucimarinus	43.68	0.00e+00	782.00
IUUC-Oga-088594	Otolemur garnettii	75.66	0.00e+00	1652.00
IUUC-Oar-090068	Ovis aries	76.60	0.00e+00	1684.00
IUUC-Pan-092114	Papio anubis	76.39	0.00e+00	1682.00
IUUC-Pma-094214	Petromyzon marinus	59.43	6.00e-54	202.00
IUUC-Pno-095154	Phaeosphaeria nodorum	51.36	0.00e+00	1046.00
IUUC-Ppa-095227	Physcomitrella patens	43.20	0.00e+00	845.00
IUUC-Pfo-097184	Poecilia formosa	87.93	0.00e+00	1873.00
IUUC-Pab-097861	Pongo abelii	75.92	0.00e+00	1648.00
IUUC-Pop-098934	Populus trichocarpa	42.88	0.00e+00	877.00
IUUC-Pca-100347	Procavia capensis	72.19	0.00e+00	1311.00
IUUC-Ppe-102012	Prunus persica	43.14	0.00e+00	849.00
IUUC-Pva-102584	Pteropus vampyrus	76.11	0.00e+00	1696.00
IUUC-Pgr-103336	Puccinia graminis	52.00	0.00e+00	1018.00
IUUC-Ptt-103939	Puccinia triticina	51.60	0.00e+00	1014.00
IUUC-Pte-104200	Pyrenophora teres	50.71	0.00e+00	1051.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	50.86	0.00e+00	1041.00
IUUC-Rno-105462	Rattus norvegicus	75.92	0.00e+00	1647.00
IUUC-Sce-106245	Saccharomyces cerevisiae	49.90	0.00e+00	996.00
IUUC-Sha-107142	Sarcophilus harrisii	75.45	0.00e+00	1655.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	53.34	0.00e+00	1071.00
IUUC-Spo-108034	Schizosaccharomyces pombe	52.57	0.00e+00	1033.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	53.85	0.00e+00	1020.00
IUUC-Smo-109211	Selaginella moellendorffii	44.01	0.00e+00	848.00
IUUC-Sit-110281	Setaria italica	44.49	0.00e+00	858.00
IUUC-Sly-110914	Solanum lycopersicum	44.49	0.00e+00	865.00
IUUC-Stu-112109	Solanum tuberosum	43.90	0.00e+00	863.00
IUUC-Sar-113737	Sorex araneus	76.30	0.00e+00	1667.00
IUUC-Sbi-114089	Sorghum bicolor	44.49	0.00e+00	858.00
IUUC-Sre-115148	Sporisorium reilianum	52.83	0.00e+00	1030.00
IUUC-Ssc-115777	Sus scrofa	76.42	0.00e+00	1676.00
IUUC-Tru-118742	Takifugu rubripes	88.79	0.00e+00	1828.00
IUUC-Tni-120401	Tetraodon nigroviridis	88.22	0.00e+00	1818.00
IUUC-Tca-121672	Theobroma cacao	43.94	0.00e+00	864.00
IUUC-Tre-122009	Trichoderma reesei	51.95	0.00e+00	1003.00
IUUC-Tvi-122259	Trichoderma virens	52.73	0.00e+00	1000.00
IUUC-Tae-125113	Triticum aestivum	44.47	0.00e+00	822.00
IUUC-Tur-126330	Triticum urartu	44.17	0.00e+00	854.00
IUUC-Tme-127055	Tuber melanosporum	51.08	0.00e+00	941.00
IUUC-Tbe-127487	Tupaia belangeri	71.88	0.00e+00	782.00
IUUC-Ttr-128331	Tursiops truncatus	75.64	0.00e+00	1655.00
IUUC-Uma-129387	Ustilago maydis	53.82	0.00e+00	1030.00
IUUC-Vda-129977	Verticillium dahliae	52.58	0.00e+00	986.00
IUUC-Vvi-130857	Vitis vinifera	43.44	0.00e+00	854.00
IUUC-Xtr-132026	Xenopus tropicalis	62.55	0.00e+00	1207.00
IUUC-Xma-133805	Xiphophorus maculatus	88.22	0.00e+00	1853.00
IUUC-Yli-134547	Yarrowia lipolytica	52.11	0.00e+00	1050.00
IUUC-Zma-135052	Zea mays	44.46	0.00e+00	857.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence