iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-054696

UUCD1 version

UUC-MaM-01142

Ensembl Protein ID

ENSMMUP00000002422.3

UniProt Accession

H9FQJ9; F7GS81; H9FQJ9_MACMU

Genbank Protein ID

AFE76908.1; AFE76909.1; AFE76910.1; AFE76911.1; AFE76912.1; AFE76913.1; AFE76914.1

Protein Name

Inactive ubiquitin carboxyl-terminal hydrolase 54

Genbank Nucleotide ID

JSUE03043572; JU333154; JU333155; JU333156; JU333157; JU333158; JU333159

Gene Name

USP54

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000001821.3	ENSMMUT00000002561.3	ENSMMUP00000002422.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.00e-24	86.9	32	349

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNl..gNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavspre.....llkalkkeaee 83
           Gl+N   +N+C++NS+LQ+L+++  +r+ + + +++k+  +       ++ ++l+ +f++++ +++++v p++     l k++++e+ +
   Q: 32   GLSNEpgQNSCFLNSALQVLWHLDIFRRSFRQLTTHKCMGD------SCIFCALKGIFNQFQ-CSSEKVLPSDtlrsaLAKTFQDEQ-R 112
           88887668******************************986......59************5.555555555543333555555444.5 PP
   S: 84   fsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           f+     Da E+++ ll +++ ++                    de +e+  + ++++ ++ F ++l +q++c +c+ +s    pf+++
   Q: 113  FQLGIMDDAAECFENLLMRIHFHI-------------------ADETKEDICTAQHCISHQKFAMTLFEQCVCTSCGATSDPL-PFIQM 181
           99**********************...................3455677899*************************99766.9**** PP
   S: 173  slpvpgkeetkke.........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkk 252
              ++  + +++             +++ +  ++ +  g+ +   ++c ++ +  +++   + P+++++ L +   s + +  e +  +
   Q: 182  VHYISTTSLCNQAicmlerrekPSPSMFGELLQNASTMGDLRNCPSNCGERIR-IRRVL-MNAPQIITIGLVWD--SDHSDLAEDVIHS 266
           *****999988889999999985556666666677777666667777777664.56655.566**********9..3333444444444 PP
   S: 253  vefpleLdlsp..fctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtev..keeevleetg...staYvl 333
           + +   L+l    f ++ ++  k+++ Y L+++++++G     HY ++  ++k + W++fdD +V+e+  k+++v++++     ++ +l
   Q: 267  LGTC--LKLGDlfFRVT-DDRAKQSELY-LVGMICYYG----KHYSTFFFQTKIRkWMYFDDAHVKEIgpKWKDVVTKCIkghYQPLLL 347
           4444..55555213333.3333335555.*********....9*****99987767************766899988655555555566 PP
   S: 334  fY 335
           +Y
   Q: 348  LY 349
           66 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MSWKRNYFSG GRGSVQGMFA PRSSTSIAPS KGLSNEPGQN SCFLNSALQV LWHLDIFRRS 60
FRQLTTHKCM GDSCIFCALK GIFNQFQCSS EKVLPSDTLR SALAKTFQDE QRFQLGIMDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATATGAAGT GAAGTTTAGA TATCTCTGTG TTAGGATTAC TGTATACCAA TAAATAGACT 60
GCTATGGCAA AGTAAATGTT TTCTTAGAGG TAGTGGAACT GAGGGCAAAC TTGAGTTGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR028889--USP_dom

PROSITE

PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000820	Aegilops tauschii	29.76	1.00e-18	87.00
IUUC-Aml-001414	Ailuropoda melanoleuca	86.84	0.00e+00	2567.00
IUUC-Atr-002451	Amborella trichopoda	30.35	2.00e-37	152.00
IUUC-Apl-004044	Anas platyrhynchos	79.44	0.00e+00	1230.00
IUUC-Aca-004351	Anolis carolinensis	58.67	0.00e+00	1553.00
IUUC-Aly-005468	Arabidopsis lyrata	32.78	2.00e-43	171.00
IUUC-Ath-006682	Arabidopsis thaliana	32.49	2.00e-42	169.00
IUUC-Ame-011525	Astyanax mexicanus	61.37	0.00e+00	983.00
IUUC-Bta-013344	Bos taurus	85.13	0.00e+00	2529.00
IUUC-Bdi-015058	Brachypodium distachyon	32.13	5.00e-41	164.00
IUUC-Bol-015670	Brassica oleracea	31.78	1.00e-39	158.00
IUUC-Bra-016731	Brassica rapa	32.36	7.00e-42	167.00
IUUC-Cja-018724	Callithrix jacchus	94.42	0.00e+00	2829.00
IUUC-Cfa-021222	Canis familiaris	86.51	0.00e+00	2625.00
IUUC-Cpo-021795	Cavia porcellus	85.34	0.00e+00	2092.00
IUUC-Cre-022697	Chlamydomonas reinhardtii	23.80	4.00e-17	85.50
IUUC-Csa-023262	Chlorocebus sabaeus	98.81	0.00e+00	3070.00
IUUC-Cho-024422	Choloepus hoffmanni	83.31	0.00e+00	2040.00
IUUC-Cin-025752	Ciona intestinalis	68.60	8.00e-48	182.00
IUUC-Csv-026063	Ciona savignyi	56.10	6.00e-112	397.00
IUUC-Dre-028046	Danio rerio	64.61	0.00e+00	967.00
IUUC-Dno-029417	Dasypus novemcinctus	81.59	0.00e+00	2368.00
IUUC-Dor-030653	Dipodomys ordii	73.59	0.00e+00	997.00
IUUC-Dme-032071	Drosophila melanogaster	53.82	2.00e-104	374.00
IUUC-Ete-032692	Echinops telfairi	66.53	0.00e+00	760.00
IUUC-Eca-033235	Equus caballus	86.74	0.00e+00	2270.00
IUUC-Eeu-034975	Erinaceus europaeus	64.83	0.00e+00	900.00
IUUC-Fca-036070	Felis catus	85.66	0.00e+00	2611.00
IUUC-Fal-037089	Ficedula albicollis	60.41	0.00e+00	1669.00
IUUC-Gmo-038653	Gadus morhua	74.67	3.00e-173	600.00
IUUC-Gga-041241	Gallus gallus	60.99	0.00e+00	1668.00
IUUC-Gac-042157	Gasterosteus aculeatus	80.46	0.00e+00	686.00
IUUC-Gma-043273	Glycine max	31.20	1.00e-37	152.00
IUUC-Ggo-045626	Gorilla gorilla	96.62	0.00e+00	2947.00
IUUC-Hsa-045767	Homo sapiens	96.80	0.00e+00	2952.00
IUUC-Hvu-047657	Hordeum vulgare	31.67	5.00e-42	167.00
IUUC-Itr-048187	Ictidomys tridecemlineatus	76.50	0.00e+00	2352.00
IUUC-Lch-049712	Latimeria chalumnae	87.53	0.00e+00	715.00
IUUC-Lpe-051572	Leersia perrieri	32.05	6.00e-39	157.00
IUUC-Loc-052615	Lepisosteus oculatus	66.20	0.00e+00	1025.00
IUUC-Laf-054578	Loxodonta africana	74.92	0.00e+00	1552.00
IUUC-Meu-056841	Macropus eugenii	54.07	0.00e+00	667.00
IUUC-Mtr-058682	Medicago truncatula	29.11	4.00e-33	137.00
IUUC-Mga-059519	Meleagris gallopavo	48.97	0.00e+00	1138.00
IUUC-Mmr-060701	Microcebus murinus	87.72	0.00e+00	2555.00
IUUC-Mdo-062433	Monodelphis domestica	68.81	0.00e+00	1961.00
IUUC-Mmu-063480	Mus musculus	70.68	0.00e+00	1453.00
IUUC-Mpu-066404	Mustela putorius furo	86.62	0.00e+00	2660.00
IUUC-Mlu-067841	Myotis lucifugus	76.50	0.00e+00	1564.00
IUUC-Nle-070110	Nomascus leucogenys	97.15	0.00e+00	2561.00
IUUC-Opr-070676	Ochotona princeps	85.54	0.00e+00	1368.00
IUUC-Ont-072289	Oreochromis niloticus	71.10	0.00e+00	712.00
IUUC-Oan-073551	Ornithorhynchus anatinus	66.17	0.00e+00	1670.00
IUUC-Ocu-074729	Oryctolagus cuniculus	86.60	0.00e+00	2594.00
IUUC-Obr-076268	Oryza brachyantha	33.24	3.00e-42	167.00
IUUC-Ogl-077138	Oryza glaberrima	32.35	2.00e-39	158.00
IUUC-Oin-079125	Oryza indica	32.35	3.00e-39	158.00
IUUC-Opu-083823	Oryza punctata	32.94	6.00e-40	160.00
IUUC-Ola-086742	Oryzias latipes	82.09	0.00e+00	647.00
IUUC-Oga-088920	Otolemur garnettii	90.08	0.00e+00	2221.00
IUUC-Oar-089644	Ovis aries	85.13	0.00e+00	2526.00
IUUC-Ptr-091530	Pan troglodytes	96.74	0.00e+00	2537.00
IUUC-Pan-092190	Papio anubis	99.70	0.00e+00	1734.00
IUUC-Psi-094022	Pelodiscus sinensis	60.21	0.00e+00	1639.00
IUUC-Pma-094745	Petromyzon marinus	59.89	2.00e-134	472.00
IUUC-Pfo-096072	Poecilia formosa	79.23	0.00e+00	700.00
IUUC-Pab-097979	Pongo abelii	96.90	0.00e+00	2341.00
IUUC-Pop-099539	Populus trichocarpa	31.69	1.00e-37	152.00
IUUC-Pca-101005	Procavia capensis	71.90	0.00e+00	2009.00
IUUC-Ppe-101918	Prunus persica	30.90	9.00e-39	156.00
IUUC-Pva-103125	Pteropus vampyrus	85.11	0.00e+00	2476.00
IUUC-Rno-105463	Rattus norvegicus	76.71	0.00e+00	2274.00
IUUC-Sha-107164	Sarcophilus harrisii	68.06	0.00e+00	1863.00
IUUC-Sit-110021	Setaria italica	32.26	2.00e-37	152.00
IUUC-Sly-110975	Solanum lycopersicum	31.34	3.00e-39	157.00
IUUC-Stu-112904	Solanum tuberosum	31.40	2.00e-37	152.00
IUUC-Sar-113423	Sorex araneus	64.24	0.00e+00	882.00
IUUC-Sbi-114345	Sorghum bicolor	32.84	2.00e-41	165.00
IUUC-Ssc-116206	Sus scrofa	85.48	0.00e+00	2514.00
IUUC-Tgu-116521	Taeniopygia guttata	94.24	0.00e+00	793.00
IUUC-Tru-118155	Takifugu rubripes	70.20	9.00e-173	599.00
IUUC-Tsy-118998	Tarsius syrichta	85.25	0.00e+00	2331.00
IUUC-Tni-120257	Tetraodon nigroviridis	80.87	0.00e+00	664.00
IUUC-Tca-121692	Theobroma cacao	31.87	2.00e-38	155.00
IUUC-Tae-125619	Triticum aestivum	31.94	9.00e-43	169.00
IUUC-Tur-126027	Triticum urartu	31.67	1.00e-42	169.00
IUUC-Tbe-128072	Tupaia belangeri	68.43	1.00e-160	560.00
IUUC-Ttr-128290	Tursiops truncatus	85.06	0.00e+00	1977.00
IUUC-Vpa-130213	Vicugna pacos	83.87	0.00e+00	2133.00
IUUC-Vvi-131652	Vitis vinifera	31.20	9.00e-39	156.00
IUUC-Xtr-131831	Xenopus tropicalis	54.05	0.00e+00	1446.00
IUUC-Xma-133409	Xiphophorus maculatus	60.12	0.00e+00	843.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence