iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012369

UUCD1 version

UUC-BoT-00033

Ensembl Protein ID

ENSBTAP00000001000.5

UniProt Accession

A4FV15; F1MWK7; A4FV15_BOVIN

Genbank Protein ID

AAI23607.1

Protein Name

PIAS4 protein

Genbank Nucleotide ID

DAAA02019628

Gene Name

PIAS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000000753.5	ENSBTAT00000001000.5	ENSBTAP00000001000.5

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	94.54	0.00e+00	909.00	IUUC-Hsa-045784
E3 activity/RING/RING	27.42	2.00e-28	121.00	IUUC-Sce-106398

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Bos taurus

Protein Sequence
(Fasta)

MAAELVEAKN MVMSFRVSDL QMLLGFVGRS KSGLKHELVT RALQLVQFDC SPELFKKIKE 60
LYETRYAKKS SEPVPQPHRP LDPLTMHSTY ERASSVPRTP LTGPNIDYPV LYGKYLNGLG 120

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Nucleotide Sequence
(Fasta)

GCTGGTGGCC AAGATGGCGG CGGAACTGGT GGAGGCCAAA GTGAGTGAGC GGCGGCGGCG 60
CCGGCCAGGG CGGGCGGGGG TCGGGGGCCG GGCGGCAGGC CGAGGTCTGT GCCTTCCGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027224--PIAS4
IPR023321--PINIT
IPR003034--SAP_dom
IPR004181--Znf_MIZ

PROSITE

PS51466--PINIT
PS50800--SAP
PS51044--ZF_SP_RING

Pfam

PF14324--PINIT
PF02891--zf-MIZ

SMART

SM00513--SAP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005654--C:nucleoplasm
GO:1990234--C:transferase complex
GO:0003677--F:DNA binding
GO:0061665--F:SUMO ligase activity
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902174--P:positive regulation of keratinocyte apoptotic process
GO:0033235--P:positive regulation of protein sumoylation

KEGG

bta:534722

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001745	Ailuropoda melanoleuca	95.09	0.00e+00	898.00
IUUC-Apl-003765	Anas platyrhynchos	82.87	0.00e+00	828.00
IUUC-Ame-010763	Astyanax mexicanus	59.87	5.00e-147	514.00
IUUC-Cja-019450	Callithrix jacchus	94.15	0.00e+00	904.00
IUUC-Cfa-020933	Canis familiaris	96.50	0.00e+00	918.00
IUUC-Cpo-022112	Cavia porcellus	93.46	0.00e+00	864.00
IUUC-Csa-023913	Chlorocebus sabaeus	81.43	0.00e+00	736.00
IUUC-Cgl-026533	Colletotrichum gloeosporioides	28.47	3.00e-35	142.00
IUUC-Dre-027609	Danio rerio	60.05	2.00e-143	501.00
IUUC-Dno-029664	Dasypus novemcinctus	75.43	4.00e-155	541.00
IUUC-Ete-032988	Echinops telfairi	92.43	7.00e-172	596.00
IUUC-Eca-034430	Equus caballus	91.41	0.00e+00	890.00
IUUC-Fca-035968	Felis catus	97.60	1.00e-169	588.00
IUUC-Fal-037449	Ficedula albicollis	84.06	0.00e+00	815.00
IUUC-Fso-038103	Fusarium solani	34.72	7.00e-27	114.00
IUUC-Gmo-038925	Gadus morhua	61.52	1.00e-139	489.00
IUUC-Ggr-039896	Gaeumannomyces graminis	32.48	9.00e-30	124.00
IUUC-Gga-040362	Gallus gallus	85.80	0.00e+00	857.00
IUUC-Gac-042353	Gasterosteus aculeatus	59.82	2.00e-134	472.00
IUUC-Ggo-044810	Gorilla gorilla	92.98	0.00e+00	865.00
IUUC-Hsa-045784	Homo sapiens	95.13	0.00e+00	915.00
IUUC-Itr-048486	Ictidomys tridecemlineatus	93.07	0.00e+00	885.00
IUUC-Lch-049727	Latimeria chalumnae	71.96	9.00e-153	532.00
IUUC-Laf-054261	Loxodonta africana	93.59	0.00e+00	913.00
IUUC-Mcc-054931	Macaca mulatta	92.98	0.00e+00	899.00
IUUC-Meu-056468	Macropus eugenii	87.94	0.00e+00	878.00
IUUC-Mpo-057405	Magnaporthe poae	33.06	7.00e-29	122.00
IUUC-Mtr-058267	Medicago truncatula	33.33	3.00e-18	87.00
IUUC-Mga-059981	Meleagris gallopavo	89.09	0.00e+00	710.00
IUUC-Mvi-060421	Microbotryum violaceum	29.07	2.00e-27	117.00
IUUC-Mmr-061181	Microcebus murinus	92.06	0.00e+00	860.00
IUUC-Mdo-062345	Monodelphis domestica	87.55	0.00e+00	876.00
IUUC-Mmu-063197	Mus musculus	87.96	0.00e+00	846.00
IUUC-Mpu-066275	Mustela putorius furo	94.55	0.00e+00	907.00
IUUC-Mlu-067194	Myotis lucifugus	97.09	0.00e+00	931.00
IUUC-Ncr-068929	Neurospora crassa	27.70	1.00e-27	117.00
IUUC-Ont-072227	Oreochromis niloticus	59.82	7.00e-140	490.00
IUUC-Obr-076179	Oryza brachyantha	32.58	1.00e-20	95.10
IUUC-Ola-086865	Oryzias latipes	60.10	1.00e-137	483.00
IUUC-Oga-088945	Otolemur garnettii	94.74	0.00e+00	919.00
IUUC-Oar-089412	Ovis aries	95.90	0.00e+00	890.00
IUUC-Ptr-091550	Pan troglodytes	85.53	0.00e+00	643.00
IUUC-Pan-092183	Papio anubis	94.15	0.00e+00	913.00
IUUC-Psi-093003	Pelodiscus sinensis	83.85	0.00e+00	838.00
IUUC-Pfo-096704	Poecilia formosa	60.00	4.00e-142	498.00
IUUC-Pab-097923	Pongo abelii	97.90	0.00e+00	767.00
IUUC-Pca-100249	Procavia capensis	78.24	4.00e-146	510.00
IUUC-Pva-102562	Pteropus vampyrus	92.46	0.00e+00	859.00
IUUC-Rno-105762	Rattus norvegicus	87.96	0.00e+00	849.00
IUUC-Sce-106398	Saccharomyces cerevisiae	34.10	1.00e-28	121.00
IUUC-Sha-107253	Sarcophilus harrisii	86.77	0.00e+00	868.00
IUUC-Sja-107662	Schizosaccharomyces japonicus	31.27	5.00e-29	122.00
IUUC-Sar-113149	Sorex araneus	85.82	1.00e-127	450.00
IUUC-Ssc-115241	Sus scrofa	97.86	0.00e+00	939.00
IUUC-Tgu-116884	Taeniopygia guttata	84.22	0.00e+00	806.00
IUUC-Tru-118031	Takifugu rubripes	60.27	7.00e-146	510.00
IUUC-Tni-119766	Tetraodon nigroviridis	60.27	4.00e-141	494.00
IUUC-Ttr-128556	Tursiops truncatus	87.28	0.00e+00	756.00
IUUC-Xtr-131866	Xenopus tropicalis	76.78	0.00e+00	765.00
IUUC-Xma-133963	Xiphophorus maculatus	60.27	8.00e-136	477.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence