iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000005758.8	ENSRNOT00000044331.6	ENSRNOP00000045550.5
ENSRNOG00000005758.8	ENSRNOT00000008596.7	ENSRNOP00000008596.5

Annotation

mRNA Expression
ArrayExpress
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.10e-10	42.2	928	988

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtg 63
           +Dv++ v+g+ f ahk+ L ++S+ F+al++++  +   + +vei  v++  f+ ++++lY g
   Q: 928  SDVTFLVEGRPFYAHKVLLFTASPRFKALLSSKPTND--STCVEIGYVKYPIFQLVMQYLYYG 988
           6*****************************8888754..68********************87 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MARRGKKPVV RTLEDLTLDS GYGGAADSVR SSNLSLCCSD SHPASPYGGS CWPPLADSMH 60
SRHNSFDTVN TALVEDSEGL DCAGQHCSRL LPDLDEVPWT LQELELLLLR SRDPRAGPAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCAGGA GAGGTAAGAA GCCGGTGGTG CGAACGCTGG AAGATCTGAC GCTGGACTCG 60
GGTTATGGTG GCGCGGCGGA CTCTGTGCGC TCCTCCAACT TGTCTCTGTG CTGTTCTGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR000210--BTB/POZ_dom
IPR009072--Histone-fold
IPR011333--SKP1/BTB/POZ

PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50097--BTB

Pfam

PF00023--Ank
PF12796--Ank_2
PF00651--BTB

SMART

SM00248--ANK
SM00225--BTB

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0031625--F:ubiquitin protein ligase binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030162--P:regulation of proteolysis
GO:0060395--P:SMAD protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000959	Aegilops tauschii	31.61	9.00e-22	97.80
IUUC-Aml-002105	Ailuropoda melanoleuca	98.75	0.00e+00	1153.00
IUUC-Apl-003655	Anas platyrhynchos	91.90	0.00e+00	1412.00
IUUC-Aca-005322	Anolis carolinensis	90.58	0.00e+00	1389.00
IUUC-Bta-012358	Bos taurus	96.18	0.00e+00	1526.00
IUUC-Bdi-014972	Brachypodium distachyon	31.61	2.00e-21	97.80
IUUC-Cja-019319	Callithrix jacchus	98.69	0.00e+00	1259.00
IUUC-Cfa-020978	Canis familiaris	95.81	0.00e+00	1531.00
IUUC-Cpo-021544	Cavia porcellus	86.75	0.00e+00	1345.00
IUUC-Cre-022991	Chlamydomonas reinhardtii	30.41	2.00e-18	87.40
IUUC-Csa-023119	Chlorocebus sabaeus	99.00	0.00e+00	1239.00
IUUC-Dre-027547	Danio rerio	75.91	0.00e+00	1219.00
IUUC-Dno-029865	Dasypus novemcinctus	96.87	0.00e+00	1489.00
IUUC-Ete-032268	Echinops telfairi	92.46	0.00e+00	1258.00
IUUC-Eca-033865	Equus caballus	96.06	0.00e+00	1529.00
IUUC-Eeu-034762	Erinaceus europaeus	76.93	0.00e+00	1191.00
IUUC-Fal-036663	Ficedula albicollis	88.61	0.00e+00	1380.00
IUUC-Gmo-039596	Gadus morhua	77.32	0.00e+00	992.00
IUUC-Gga-041029	Gallus gallus	93.01	0.00e+00	1384.00
IUUC-Gac-041438	Gasterosteus aculeatus	73.32	0.00e+00	1165.00
IUUC-Ggo-044802	Gorilla gorilla	95.67	0.00e+00	1527.00
IUUC-Hsa-046584	Homo sapiens	95.67	0.00e+00	1527.00
IUUC-Itr-048538	Ictidomys tridecemlineatus	94.52	0.00e+00	1333.00
IUUC-Lch-049687	Latimeria chalumnae	86.24	0.00e+00	1332.00
IUUC-Loc-051886	Lepisosteus oculatus	82.90	0.00e+00	1248.00
IUUC-Laf-053855	Loxodonta africana	91.64	0.00e+00	1052.00
IUUC-Mcc-055806	Macaca mulatta	95.67	0.00e+00	1526.00
IUUC-Mga-059197	Meleagris gallopavo	91.76	0.00e+00	1411.00
IUUC-Mmr-061287	Microcebus murinus	92.46	0.00e+00	700.00
IUUC-Mdo-062743	Monodelphis domestica	83.22	0.00e+00	1288.00
IUUC-Mmu-063972	Mus musculus	96.33	0.00e+00	1539.00
IUUC-Mpu-066794	Mustela putorius furo	95.93	0.00e+00	1527.00
IUUC-Mlu-068161	Myotis lucifugus	97.25	0.00e+00	1478.00
IUUC-Opr-070314	Ochotona princeps	85.38	0.00e+00	1240.00
IUUC-Ont-071894	Oreochromis niloticus	77.20	0.00e+00	1176.00
IUUC-Oan-073337	Ornithorhynchus anatinus	93.23	0.00e+00	1098.00
IUUC-Ocu-074865	Oryctolagus cuniculus	98.00	0.00e+00	1024.00
IUUC-Ola-087327	Oryzias latipes	74.29	0.00e+00	1109.00
IUUC-Oar-089372	Ovis aries	99.00	0.00e+00	1241.00
IUUC-Ptr-090860	Pan troglodytes	98.07	0.00e+00	1491.00
IUUC-Pan-091894	Papio anubis	95.42	0.00e+00	1520.00
IUUC-Psi-093453	Pelodiscus sinensis	92.14	0.00e+00	1398.00
IUUC-Pma-094623	Petromyzon marinus	57.97	0.00e+00	713.00
IUUC-Pfo-097384	Poecilia formosa	75.29	0.00e+00	1207.00
IUUC-Pab-097817	Pongo abelii	95.54	0.00e+00	1527.00
IUUC-Sha-107271	Sarcophilus harrisii	94.34	0.00e+00	1442.00
IUUC-Sit-110591	Setaria italica	30.46	2.00e-20	94.00
IUUC-Sbi-114795	Sorghum bicolor	33.54	3.00e-21	97.10
IUUC-Ssc-116099	Sus scrofa	95.81	0.00e+00	1529.00
IUUC-Tgu-116784	Taeniopygia guttata	91.76	0.00e+00	1409.00
IUUC-Tru-118505	Takifugu rubripes	75.95	0.00e+00	1172.00
IUUC-Tni-119849	Tetraodon nigroviridis	75.81	0.00e+00	1160.00
IUUC-Tae-125435	Triticum aestivum	31.61	8.00e-22	99.00
IUUC-Tbe-128145	Tupaia belangeri	97.92	1.00e-172	600.00
IUUC-Xtr-131913	Xenopus tropicalis	73.77	0.00e+00	1595.00
IUUC-Xma-133023	Xiphophorus maculatus	77.03	0.00e+00	1175.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence