iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-120640

UUCD1 version

UUC-TeN-00751

Ensembl Protein ID

ENSTNIP00000016786.1

UniProt Accession

H3D8E5; H3D8E5_TETNG

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000013784.1	ENSTNIT00000017000.1	ENSTNIP00000016786.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.30e-95	320.8	475	804

Active Site

Position(s)	Description	Evidence
773	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           +sdlkk+l++ef+gE+g d gG+++ef++l+++e++npd+g+f+y+++ +  ++ n++s     e++  ++++G +lg+a++++ +ldl
   Q: 475  PSDLKKQLFIEFEGEQGFDEGGLSKEFFQLVLEEIFNPDIGMFTYDDDTRVFWF-NSSSL----ENEAQYTLIGLVLGLAIYNNCILDL 558
           689******************************************999888887.55554....67999******************** PP
   S: 91   plsksfyklllgkklsledleevdpe..lykslkeikenaesdieelgldltfs.vseeilgetkeeeLkpgGenipVtneNkeeYvkl 176
           +++  +yk+l+gkk +++dl++ +p   l +slk+++e+   ++ee ++ l+f+  +++ +g+   ++Lk++Ge+ipVt +N++e+v+l
   Q: 559  HFPMIVYKKLMGKKGTFSDLSDSHPVqvLSRSLKSLLEYP-GNVEE-DMSLSFQiSHTDMFGSPVFYDLKENGEQIPVTRDNRQEFVNL 645
           ***********************986226678*******6.46655.47888883356669**************************** PP
   S: 177  vveyrlkegikeqveafreGfneviple.llslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkaf 264
           +++y l++++++q+ af++Gf  v +++ l  lF++eelellicG++++d+ +l+++t+y+ggy++d p i+ Fwe++++f++e+++ f
   Q: 646  YTDYMLNKSVETQFRAFKKGFLMVTQESpLKHLFRPEELELLICGSKKLDFGALEETTEYDGGYSKDTPIIKDFWETIRAFEEEQKRLF 734
           *************************99946679******************************************************** PP
   S: 265  LqFvTgssrlPlgGfaelkprlfvirk..dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           LqF++g+ r+P+gG+ +lk   ++i k  + +d+  P+s+TC+n L LPeYssk +l+e+Ll Ai+++kgF++
   Q: 735  LQFISGTVRAPVGGLGKLK---MTIAKngSDTDSGCPTSHTCYNILLLPEYSSKAKLRERLLKAITYAKGFGM 804
           *******************...6677747777799************************************98 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

RKRAAAKHLI EHYFLQLTEG CGNADCKNEF CASCRDFRPL DNNAAAVKAL ELYKINAKLC 60
RPPPLKKESD SPSLDSGPSP LDLSDADYSD VHYLTETTVC MILSLCEEEG DYSPLVRVIG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGAAGAGGG CAGCTGCTAA ACATCTCATT GAACACTACT TCCTGCAGTT AACAGAAGGC 60
TGTGGAAACG CTGACTGCAA AAATGAGTTT TGTGCATCGT GTCGTGACTT TCGCCCTCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR032353--AZUL
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF16558--AZUL
PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Gac-042293	Gasterosteus aculeatus	70.49	0.00e+00	1167.00
IUUC-Ont-072087	Oreochromis niloticus	72.78	0.00e+00	1211.00
IUUC-Pfo-096868	Poecilia formosa	71.60	0.00e+00	1160.00
IUUC-Tru-117763	Takifugu rubripes	88.44	0.00e+00	1458.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence