iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mtr-058367

Ensembl Protein ID

AES81658

UniProt Accession

G7KYJ6; G7KYJ6_MEDTR

Genbank Protein ID

AES81658.1

Protein Name

Ribosome biogenesis protein WDR12 homolog

Genbank Nucleotide ID

CM001223

Gene Name

MTR_7g099170

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MTR_7g099170	AES81658	AES81658

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-30	105.4	387	421
UBD/Beta-Prp	3.40e-42	146.1	291	454

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtg 33
           Ht++vt +++   +  +l+s+s+Dg++++WDlrt 
   Q: 387  HTSWVTTVKWhdKSlFHLLSASYDGKVMLWDLRTA 421
           **********75335669**************996 PP

UBD/Beta-Prp

   S: 83   tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl...ktgkllrtltggh 179
            g+ + tl gh++ v s+ + + ++++ s+s+d  ir wd+e+g+ + +++ g+    nc+ + +++  l++ G+ D +vr+Wd     t   + ++ + h
   Q: 291  EGEAFTTLVGHTQCVSSVIWPQ-RESIYSASWDHSIRKWDVEKGKNVTDIFCGKA--LNCLDIGGESsALIAVGGSDPVVRIWDPrkpGTSAPVFQFAS-H 387
           578999************9988.9***********************88887765..**********9*****************86667778888898.* PP
   S: 180  tdsvyslsfdsng.kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsi 246
           t+ v+ +++++++ ++l+s+s+dg+v lwdl+t   + t + h+d v++ + + +++ ++sg++D  +
   Q: 388  TSWVTTVKWHDKSlFHLLSASYDGKVMLWDLRTAWPLSTIESHSDKVLCADWW-KSDSVISGGADSKL 454
           *********99999***************************************.99999****99876 PP

Organism

Medicago truncatula

Functional Description
(View)

Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.

Protein Sequence
(Fasta)

MPKERPRSLT PLPRRHLPVL HSQPQKKTMM NEEDNGESST RRIQVRFVTS LPEPFKVPSS 60
AIAIPVDLTR FGLSSLVNAL LQSKDEDHKS EPFDFLIDGE FVRMSLEDFL LAKGISAERI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCAGTAG AAACTAAAAA TCAATTAAAA AATGGAACGT GCTTAACAGA AAGAAAGACC 60
TAGGTCTCTC ACACCTCTCC CGCGCCGTCA CCTTCCAGTG TTACACAGTC AGCCTCAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR012972--NLE
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR028599--WDR12/Ytm1

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08154--NLE
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0030687--C:preribosome, large subunit precursor
GO:0043021--F:ribonucleoprotein complex binding
GO:0000466--P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000463--P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000532	Aegilops tauschii	61.02	5.00e-161	560.00
IUUC-Aml-001997	Ailuropoda melanoleuca	37.04	2.00e-60	226.00
IUUC-Atr-002544	Amborella trichopoda	58.49	1.00e-149	522.00
IUUC-Apl-003981	Anas platyrhynchos	36.93	2.00e-59	222.00
IUUC-Aca-004370	Anolis carolinensis	36.32	7.00e-68	250.00
IUUC-Aly-006455	Arabidopsis lyrata	67.68	8.00e-179	619.00
IUUC-Ath-006669	Arabidopsis thaliana	67.60	4.00e-175	606.00
IUUC-Ago-007864	Ashbya gossypii	31.00	5.00e-45	174.00
IUUC-Acl-008177	Aspergillus clavatus	31.28	4.00e-44	171.00
IUUC-Afl-008617	Aspergillus flavus	30.57	1.00e-39	156.00
IUUC-Afu-008752	Aspergillus fumigatus	30.47	5.00e-39	154.00
IUUC-Ani-009136	Aspergillus nidulans	32.67	1.00e-44	173.00
IUUC-Ang-009701	Aspergillus niger	30.63	1.00e-38	153.00
IUUC-Aor-009884	Aspergillus oryzae	30.33	7.00e-40	157.00
IUUC-Ame-011432	Astyanax mexicanus	36.87	4.00e-71	261.00
IUUC-Bgr-012218	Blumeria graminis	28.41	6.00e-38	151.00
IUUC-Bta-012829	Bos taurus	36.78	2.00e-63	235.00
IUUC-Bci-013953	Botrytis cinerea	29.20	9.00e-38	150.00
IUUC-Bdi-014351	Brachypodium distachyon	63.55	1.00e-156	545.00
IUUC-Bol-016514	Brassica oleracea	66.74	1.00e-167	582.00
IUUC-Bra-016988	Brassica rapa	66.51	1.00e-167	582.00
IUUC-Cel-018569	Caenorhabditis elegans	24.72	2.00e-26	112.00
IUUC-Cja-019468	Callithrix jacchus	37.02	2.00e-60	226.00
IUUC-Cfa-020471	Canis familiaris	35.82	1.00e-58	219.00
IUUC-Cpo-022260	Cavia porcellus	37.02	5.00e-62	231.00
IUUC-Cre-022614	Chlamydomonas reinhardtii	37.72	2.00e-61	229.00
IUUC-Csa-023989	Chlorocebus sabaeus	36.54	3.00e-60	225.00
IUUC-Cho-024426	Choloepus hoffmanni	35.99	1.00e-44	173.00
IUUC-Cin-025789	Ciona intestinalis	33.57	1.00e-53	203.00
IUUC-Cne-027063	Cryptococcus neoformans	26.90	5.00e-31	128.00
IUUC-Dre-027907	Danio rerio	36.63	2.00e-69	255.00
IUUC-Dno-029225	Dasypus novemcinctus	36.93	1.00e-62	233.00
IUUC-Dor-031082	Dipodomys ordii	32.93	8.00e-28	117.00
IUUC-Dse-031308	Dothistroma septosporum	29.80	7.00e-42	164.00
IUUC-Dme-032189	Drosophila melanogaster	31.76	2.00e-49	189.00
IUUC-Ete-032247	Echinops telfairi	34.29	8.00e-55	207.00
IUUC-Eca-034285	Equus caballus	36.30	4.00e-62	231.00
IUUC-Eeu-035322	Erinaceus europaeus	33.83	1.00e-53	203.00
IUUC-Fca-036114	Felis catus	36.06	2.00e-61	229.00
IUUC-Fal-036891	Ficedula albicollis	36.56	1.00e-52	199.00
IUUC-Fox-037965	Fusarium oxysporum	25.27	6.00e-29	121.00
IUUC-Fso-038244	Fusarium solani	26.07	9.00e-30	124.00
IUUC-Gmo-039040	Gadus morhua	36.00	7.00e-71	260.00
IUUC-Ggr-040093	Gaeumannomyces graminis	25.29	3.00e-26	112.00
IUUC-Gga-040610	Gallus gallus	35.82	1.00e-63	236.00
IUUC-Gac-042117	Gasterosteus aculeatus	36.93	1.00e-66	246.00
IUUC-Gma-043756	Glycine max	83.18	0.00e+00	756.00
IUUC-Ggo-045179	Gorilla gorilla	36.78	2.00e-61	229.00
IUUC-Hsa-046114	Homo sapiens	36.78	1.00e-60	226.00
IUUC-Hvu-047331	Hordeum vulgare	62.16	5.00e-142	496.00
IUUC-Itr-048275	Ictidomys tridecemlineatus	36.30	4.00e-62	231.00
IUUC-Kpa-049304	Komagataella pastoris	30.59	3.00e-46	179.00
IUUC-Lch-050655	Latimeria chalumnae	34.38	2.00e-46	178.00
IUUC-Lpe-051675	Leersia perrieri	63.44	7.00e-163	566.00
IUUC-Loc-052868	Lepisosteus oculatus	36.67	2.00e-67	249.00
IUUC-Lma-053258	Leptosphaeria maculans	29.03	6.00e-38	152.00
IUUC-Laf-053993	Loxodonta africana	36.21	4.00e-62	231.00
IUUC-Mcc-055128	Macaca mulatta	29.54	2.00e-36	145.00
IUUC-Meu-056501	Macropus eugenii	37.43	3.00e-51	194.00
IUUC-Mor-057114	Magnaporthe oryzae	28.21	2.00e-37	149.00
IUUC-Mla-059107	Melampsora laricipopulina	27.14	8.00e-34	137.00
IUUC-Mga-059745	Meleagris gallopavo	36.45	1.00e-61	229.00
IUUC-Mvi-060362	Microbotryum violaceum	25.87	4.00e-30	125.00
IUUC-Mdo-062257	Monodelphis domestica	36.54	6.00e-66	244.00
IUUC-Mmu-063546	Mus musculus	35.93	1.00e-62	232.00
IUUC-Mac-065540	Musa acuminata	62.21	4.00e-161	560.00
IUUC-Mpu-066284	Mustela putorius furo	36.06	4.00e-62	231.00
IUUC-Mlu-067241	Myotis lucifugus	36.78	1.00e-62	233.00
IUUC-Nfi-068260	Neosartorya fischeri	30.47	2.00e-40	159.00
IUUC-Ncr-068719	Neurospora crassa	28.27	8.00e-31	127.00
IUUC-Nle-068981	Nomascus leucogenys	36.78	3.00e-59	221.00
IUUC-Opr-071218	Ochotona princeps	34.41	2.00e-56	212.00
IUUC-Ont-071646	Oreochromis niloticus	36.21	9.00e-64	236.00
IUUC-Oan-073453	Ornithorhynchus anatinus	36.45	2.00e-71	262.00
IUUC-Ocu-074008	Oryctolagus cuniculus	36.93	2.00e-63	235.00
IUUC-Oba-075712	Oryza barthii	51.17	7.00e-123	433.00
IUUC-Obr-076721	Oryza brachyantha	60.23	2.00e-158	551.00
IUUC-Ogl-077229	Oryza glaberrima	60.78	7.00e-161	559.00
IUUC-Ogu-078977	Oryza glumaepatula	51.64	8.00e-123	432.00
IUUC-Oin-079683	Oryza indica	61.01	2.00e-160	557.00
IUUC-Olo-080291	Oryza longistaminata	52.15	7.00e-86	309.00
IUUC-Ome-081834	Oryza meridionalis	62.82	1.00e-161	562.00
IUUC-Oni-082507	Oryza nivara	58.94	2.00e-150	524.00
IUUC-Opu-083396	Oryza punctata	61.68	6.00e-162	563.00
IUUC-Oru-085220	Oryza rufipogon	59.17	6.00e-151	526.00
IUUC-Osa-085767	Oryza sativa	61.01	2.00e-160	557.00
IUUC-Ola-087420	Oryzias latipes	36.78	9.00e-70	256.00
IUUC-Olu-087740	Ostreococcus lucimarinus	34.17	7.00e-62	230.00
IUUC-Oga-088264	Otolemur garnettii	36.06	4.00e-60	224.00
IUUC-Oar-089335	Ovis aries	36.54	4.00e-63	234.00
IUUC-Ptr-091320	Pan troglodytes	36.78	1.00e-60	226.00
IUUC-Pan-092833	Papio anubis	37.17	2.00e-60	225.00
IUUC-Psi-093504	Pelodiscus sinensis	35.10	2.00e-60	225.00
IUUC-Pma-094189	Petromyzon marinus	37.08	4.00e-63	234.00
IUUC-Pno-094929	Phaeosphaeria nodorum	28.99	8.00e-37	147.00
IUUC-Ppa-095429	Physcomitrella patens	51.72	8.00e-128	449.00
IUUC-Pfo-096337	Poecilia formosa	36.93	2.00e-68	252.00
IUUC-Pab-097571	Pongo abelii	36.54	2.00e-60	225.00
IUUC-Pop-099977	Populus trichocarpa	69.27	0.00e+00	634.00
IUUC-Pca-100394	Procavia capensis	35.31	1.00e-51	196.00
IUUC-Ppe-101848	Prunus persica	70.23	0.00e+00	648.00
IUUC-Pva-102921	Pteropus vampyrus	34.68	8.00e-27	114.00
IUUC-Pgr-103637	Puccinia graminis	27.29	8.00e-34	137.00
IUUC-Ptt-103781	Puccinia triticina	27.44	2.00e-32	133.00
IUUC-Pte-104135	Pyrenophora teres	31.09	4.00e-40	159.00
IUUC-Pyt-104609	Pyrenophora triticirepentis	30.07	3.00e-39	155.00
IUUC-Rno-105114	Rattus norvegicus	35.97	7.00e-62	230.00
IUUC-Sce-106401	Saccharomyces cerevisiae	31.24	2.00e-47	182.00
IUUC-Sha-107122	Sarcophilus harrisii	37.80	8.00e-64	236.00
IUUC-Sja-107766	Schizosaccharomyces japonicus	27.77	4.00e-36	145.00
IUUC-Spo-108134	Schizosaccharomyces pombe	28.96	5.00e-37	148.00
IUUC-Ssl-108398	Sclerotinia sclerotiorum	30.27	7.00e-41	160.00
IUUC-Smo-108720	Selaginella moellendorffii	47.22	2.00e-116	411.00
IUUC-Sit-110354	Setaria italica	60.93	4.00e-160	556.00
IUUC-Sly-111023	Solanum lycopersicum	61.32	2.00e-164	571.00
IUUC-Stu-112778	Solanum tuberosum	66.21	7.00e-170	589.00
IUUC-Sar-113596	Sorex araneus	33.33	1.00e-44	173.00
IUUC-Sbi-114193	Sorghum bicolor	60.56	3.00e-154	537.00
IUUC-Ssc-116066	Sus scrofa	36.30	2.00e-62	232.00
IUUC-Tgu-117048	Taeniopygia guttata	36.93	8.00e-59	220.00
IUUC-Tsy-119573	Tarsius syrichta	25.44	2.00e-24	106.00
IUUC-Tni-119820	Tetraodon nigroviridis	36.78	4.00e-65	241.00
IUUC-Tca-121605	Theobroma cacao	70.80	0.00e+00	659.00
IUUC-Tre-121947	Trichoderma reesei	25.47	1.00e-32	133.00
IUUC-Tvi-122481	Trichoderma virens	25.05	2.00e-32	132.00
IUUC-Tae-123504	Triticum aestivum	61.02	7.00e-161	559.00
IUUC-Tur-126586	Triticum urartu	61.65	3.00e-148	517.00
IUUC-Tme-126900	Tuber melanosporum	30.79	3.00e-49	188.00
IUUC-Tbe-127736	Tupaia belangeri	30.75	2.00e-33	135.00
IUUC-Ttr-129041	Tursiops truncatus	31.49	5.00e-45	174.00
IUUC-Vpa-130260	Vicugna pacos	36.54	4.00e-63	234.00
IUUC-Vvi-131009	Vitis vinifera	69.63	0.00e+00	644.00
IUUC-Xtr-132083	Xenopus tropicalis	37.26	1.00e-65	242.00
IUUC-Xma-133094	Xiphophorus maculatus	35.97	5.00e-68	250.00
IUUC-Yli-134531	Yarrowia lipolytica	26.05	2.00e-26	112.00
IUUC-Zma-135509	Zea mays	61.31	2.00e-162	564.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence