iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000015169.1	ENSONIT00000019107.1	ENSONIP00000019090.1
ENSONIG00000015169.1	ENSONIT00000019108.1	ENSONIP00000019091.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.40e-14	52.6	168	222

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++ ++++ +n+deL++ kGd + v    ++++gW++g  +l+ k G fP+n+v++l+
   Q: 168  LVRARFPFQQTNEDELSFSKGDLIIVT--RQEEGGWWEG--TLKDKTGWFPSNYVRELK 222
           58899*******************996..9999******..8**************986 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MNSAEQTVTW LITLGVLESP KKSISDPEAF LQASLQDGAV LCRLLERLRP GTVDKFFQEP 60
RSDSECQRNI TEFVKGCGAF GFLSLKPFEV NDLLQGLNFS KVLNSLVALN KATEDLSVSG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTGGAGCAG CTGGTTTGAC AATAATGCCG CTGCTACAGT TGTGTATGAG CAAAGGTGAT 60
GCCAACATCC GCTGAGGGAG AGCCAGAGCG CAGACAATGA GGGGCTGTTA GAGGAAGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00307--CH
PF00621--RhoGEF
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0001525--P:angiogenesis
GO:0001935--P:endothelial cell proliferation
GO:0055113--P:epiboly involved in gastrulation with mouth forming second
GO:0035556--P:intracellular signal transduction
GO:0071896--P:protein localization to adherens junction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Gac-041950	Gasterosteus aculeatus	76.99	0.00e+00	1246.00
IUUC-Ola-086601	Oryzias latipes	82.29	0.00e+00	1220.00
IUUC-Pfo-096932	Poecilia formosa	82.11	0.00e+00	1378.00
IUUC-Ptt-103726	Puccinia triticina	39.74	3.00e-11	62.40
IUUC-Tru-118301	Takifugu rubripes	81.37	0.00e+00	1222.00
IUUC-Tni-120394	Tetraodon nigroviridis	79.65	0.00e+00	1103.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence