iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118574

UUCD1 version

UUC-TaR-01146

Ensembl Protein ID

ENSTRUP00000043581.1

UniProt Accession

H2V300; H2V300_TAKRU

Protein Name

Uncharacterized protein

Gene Name

USP50

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000017017.1	ENSTRUT00000043726.1	ENSTRUP00000043580.1
ENSTRUG00000017017.1	ENSTRUT00000043727.1	ENSTRUP00000043581.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.00e-81	273.3	1	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl N gN+CY+N+vLQcL ++ +l e+ll+   +++++e   ++k +l   + +l++++w +  ++ +p e  ++l+++ ++f++y+qq
   Q: 1    GLDNSGNSCYLNAVLQCLCSTVPLVEYLLN---QDTQAE-LAQSKCRLGGVFVQLLKKMWMGGYSSCAPVEARSVLGSILPQFNNYSQQ 85
           9*****************************...333333.257899******************************************* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           DaqE+l fll+ l+++lkk ++ +  +++ ++++++ d+++      +++ +s+lF+gq++  + c +cd++  + ++f+ lslp+p +
   Q: 86   DAQELLLFLLNVLHDDLKKVTRRQMRSSTLQQRRKQGDKRSIAAAAWETTAVSQLFEGQMSFMTLCMHCDHQAHSSQTFTVLSLPIPTD 174
           *****************99888888888888888888888899999999**************************************99 PP
   S: 180  eetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctsp 268
           +  +k +++dcL+ f+++  l+g +++ c+ c  ++e++  + l++ Pe+L+lhLkRf   +++k++ k+ ++v f+ +L++spf++sp
   Q: 175  T--SKCTIEDCLSLFFQQTILTGGEQMLCSVCGLRRETTVFTCLDNPPEILTLHLKRF--GCKGKNQVKLRTNVLFNMKLNISPFLSSP 259
           9..458****************************************************..8899999*********************9 PP
   S: 269  eekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
           e++     +Y+L+avv+H+G+l+ GHY+a++++  +g W +fdDs V+ev+e+ v++   s+aY+l+Y rr
   Q: 260  EQN----SSYSLYAVVNHTGNLNMGHYTALCQStITGTWHHFDDSAVKEVQEDFVQS---SSAYMLLYSRR 323
           975....69***********************944666*******************...********985 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

GLDNSGNSCY LNAVLQCLCS TVPLVEYLLN QDTQAELAQS KCRLGGVFVQ LLKKMWMGGY 60
SSCAPVEARS VLGSILPQFN NYSQQDAQEL LLFLLNVLHD DLKKVTRRQM RSSTLQQRRK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGTATGCG GTTTGGACAA CTCGGGCAAC TCCTGCTACT TGAACGCCGT GTTACAGTGT 60
CTGTGCTCCA CTGTGCCCCT GGTGGAGTAC CTCCTTAATC AGGACACTCA AGCAGAACTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ete-032570	Echinops telfairi	40.80	6.00e-30	124.00
IUUC-Gac-042261	Gasterosteus aculeatus	66.67	2.00e-120	424.00
IUUC-Loc-051880	Lepisosteus oculatus	49.40	3.00e-84	306.00
IUUC-Ont-072200	Oreochromis niloticus	70.73	6.00e-121	427.00
IUUC-Ola-086857	Oryzias latipes	62.43	2.00e-113	401.00
IUUC-Pfo-096718	Poecilia formosa	60.24	3.00e-100	358.00
IUUC-Tni-120385	Tetraodon nigroviridis	77.01	8.00e-134	469.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence