iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062592

UUCD1 version

UUC-MoD-00886

Ensembl Protein ID

ENSMODP00000006105.3

UniProt Accession

F7FLA2; F7FLA2_MONDO

Protein Name

Uncharacterized protein

Gene Name

WDSUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000004957.3	ENSMODT00000006234.3	ENSMODP00000006105.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	8.50e-26	90.0	407	478
E3 adaptor/Cullin RING/DCX/DWD	6.90e-38	127.2	11	43
UBD/Beta-Prp	4.10e-53	180.6	7	217

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
           +p+eflCpI+ elM++Pv++++G++y++++Ie w+ ++++t+P+t+  l +  l+Pn tl+  i++w+e+++
   Q: 407  IPDEFLCPITRELMKEPVIASDGYSYEKEAIENWITKKKRTSPMTNLVLPSLVLTPNRTLKMAINRWLETHQ 478
           8********************************************************************997 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgv 34
           H d+v+c+afs+ ll+++s D+ti++++l +++
   Q: 11   HGDDVNCCAFSSSLLATCSLDKTIRLYSLNDFN 43
           9*********548***************98765 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtl 90
           tl +h ++v +c +f  ++sllat s d+ti+++++ + +    + l+ h+ +v +++fsp+g il+++s+D+t  +w+ +tg ++ +l
   Q: 7    TLADHGDDV-NCCAF--SSSLLATCSLDKTIRLYSLNDFNElpYSPLKVHTYAVHCCCFSPSGHILASCSTDGTTVLWNTQTGHILAVL 92
           566666655.55899..9*******************977778899******************************************* PP
   S: 91   kghe.dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgg 178
           ++ + + v+ ++fsp++ +lvsG +d  +  w+++t++ ++ + s++dg+    ++ p+g+ +v+Gs  + + +Wd   +++l+  +  
   Q: 93   NQPNgSPVRICKFSPDSMYLVSGAADGSVVSWNMQTYKLFR-CGSVKDGSLVACAFCPNGSHFVTGSSCGDLTVWDD-KMRCLHSEKA- 178
           9766267**********************************.**********************************8.6678888877. PP
   S: 179  htdsvyslsfdsng..........kelvsgsldgtvklw 207
           h+  +++ +f+s+           ++++s+++d ++klw
   Q: 179  HDLGITCCDFSSQPisdddygpqfFRMASCGQDCQIKLW 217
           *********99988999999**99*************** PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MVTLIHTLAD HGDDVNCCAF SSSLLATCSL DKTIRLYSLN DFNELPYSPL KVHTYAVHCC 60
CFSPSGHILA SCSTDGTTVL WNTQTGHILA VLNQPNGSPV RICKFSPDSM YLVSGAADGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTTACACA AGGAGTCAAA TCCTGAGAGT TCATCTAGTC ATCTTCGTTT TACAAATGAA 60
GAAAGTGGCT CCCCAGGGAG CTGAAGTGAC TTGTTTAAAG TCCCAGGGTT GTTCCTAGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

mdo:100015314

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001614	Ailuropoda melanoleuca	83.51	0.00e+00	835.00
IUUC-Apl-003529	Anas platyrhynchos	74.53	0.00e+00	756.00
IUUC-Aca-004257	Anolis carolinensis	70.20	0.00e+00	701.00
IUUC-Ame-011357	Astyanax mexicanus	52.11	2.00e-114	406.00
IUUC-Bta-013032	Bos taurus	80.62	0.00e+00	805.00
IUUC-Cja-018743	Callithrix jacchus	82.05	0.00e+00	822.00
IUUC-Cfa-021197	Canis familiaris	82.67	0.00e+00	834.00
IUUC-Cpo-022279	Cavia porcellus	80.38	0.00e+00	809.00
IUUC-Csa-023954	Chlorocebus sabaeus	83.92	0.00e+00	839.00
IUUC-Cho-025083	Choloepus hoffmanni	67.45	5.00e-143	500.00
IUUC-Cin-025786	Ciona intestinalis	35.20	6.00e-81	294.00
IUUC-Dre-028087	Danio rerio	57.20	2.00e-144	505.00
IUUC-Dno-028919	Dasypus novemcinctus	83.92	0.00e+00	837.00
IUUC-Dor-031112	Dipodomys ordii	80.79	0.00e+00	797.00
IUUC-Ete-032405	Echinops telfairi	80.35	6.00e-166	576.00
IUUC-Eca-033254	Equus caballus	83.30	0.00e+00	836.00
IUUC-Eeu-034545	Erinaceus europaeus	76.83	0.00e+00	751.00
IUUC-Fca-035482	Felis catus	83.51	0.00e+00	832.00
IUUC-Fal-036976	Ficedula albicollis	60.53	6.00e-162	563.00
IUUC-Gmo-039213	Gadus morhua	53.65	6.00e-136	477.00
IUUC-Gga-040561	Gallus gallus	73.12	0.00e+00	738.00
IUUC-Gac-041471	Gasterosteus aculeatus	57.59	2.00e-139	488.00
IUUC-Ggo-045503	Gorilla gorilla	83.72	0.00e+00	840.00
IUUC-Hsa-045910	Homo sapiens	83.51	0.00e+00	840.00
IUUC-Itr-048214	Ictidomys tridecemlineatus	79.21	3.00e-180	624.00
IUUC-Loc-052307	Lepisosteus oculatus	60.12	9.00e-171	593.00
IUUC-Laf-053587	Loxodonta africana	82.67	0.00e+00	822.00
IUUC-Mcc-055679	Macaca mulatta	83.72	0.00e+00	837.00
IUUC-Meu-055962	Macropus eugenii	76.41	0.00e+00	700.00
IUUC-Mga-059652	Meleagris gallopavo	73.07	0.00e+00	745.00
IUUC-Mmr-060943	Microcebus murinus	79.42	0.00e+00	795.00
IUUC-Mmu-063577	Mus musculus	78.08	0.00e+00	775.00
IUUC-Mpu-066422	Mustela putorius furo	81.84	0.00e+00	823.00
IUUC-Mlu-067250	Myotis lucifugus	81.21	0.00e+00	811.00
IUUC-Nle-069517	Nomascus leucogenys	82.67	0.00e+00	829.00
IUUC-Opr-070776	Ochotona princeps	81.84	0.00e+00	818.00
IUUC-Ont-071821	Oreochromis niloticus	56.94	2.00e-147	515.00
IUUC-Oan-073706	Ornithorhynchus anatinus	84.10	0.00e+00	836.00
IUUC-Ocu-074766	Oryctolagus cuniculus	73.91	0.00e+00	723.00
IUUC-Ola-086531	Oryzias latipes	56.04	8.00e-144	503.00
IUUC-Oga-088388	Otolemur garnettii	79.75	0.00e+00	811.00
IUUC-Oar-089748	Ovis aries	80.83	0.00e+00	806.00
IUUC-Ptr-090616	Pan troglodytes	83.19	0.00e+00	830.00
IUUC-Pan-091769	Papio anubis	83.57	1.00e-172	598.00
IUUC-Psi-093334	Pelodiscus sinensis	78.29	0.00e+00	732.00
IUUC-Pma-094383	Petromyzon marinus	49.22	4.00e-136	478.00
IUUC-Pfo-096801	Poecilia formosa	55.30	5.00e-143	501.00
IUUC-Pab-098139	Pongo abelii	81.38	0.00e+00	669.00
IUUC-Pca-100523	Procavia capensis	77.92	2.00e-150	525.00
IUUC-Pva-102286	Pteropus vampyrus	81.21	0.00e+00	788.00
IUUC-Rno-104831	Rattus norvegicus	78.08	0.00e+00	784.00
IUUC-Sha-107499	Sarcophilus harrisii	91.23	0.00e+00	907.00
IUUC-Sar-113389	Sorex araneus	79.75	0.00e+00	769.00
IUUC-Tgu-116769	Taeniopygia guttata	71.61	0.00e+00	715.00
IUUC-Tru-118774	Takifugu rubripes	54.40	1.00e-137	482.00
IUUC-Tsy-119595	Tarsius syrichta	69.64	8.00e-161	559.00
IUUC-Tni-119850	Tetraodon nigroviridis	55.58	2.00e-143	502.00
IUUC-Tur-126683	Triticum urartu	49.25	7.00e-16	79.30
IUUC-Tbe-127938	Tupaia belangeri	74.68	4.00e-132	463.00
IUUC-Ttr-128193	Tursiops truncatus	80.56	0.00e+00	679.00
IUUC-Vpa-130275	Vicugna pacos	82.05	0.00e+00	821.00
IUUC-Xtr-131982	Xenopus tropicalis	61.72	1.00e-168	586.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence