iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117589

UUCD1 version

UUC-TaR-01050

Ensembl Protein ID

ENSTRUP00000016695.1

UniProt Accession

H2SWA7; H2SWA7_TAKRU

Protein Name

Uncharacterized protein

Gene Name

cdc34b; LOC101073638

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000006796.1	ENSTRUT00000016767.1	ENSTRUP00000016695.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.30e-44	152.6	16	165

Active Site

Position(s)	Description	Evidence
105	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkl.........eiefpedYPfkPPkvkfltkifhPnvyenGkv 81
           l+ e+k+l+++p+eg+++++v+e+d+++wev+i+Gp++t Yegg+Fk+         +i+fp dYP++PP ++fltk++hPn+yenG+v
   Q: 16   LMLEMKSLQEQPVEGFKITLVNEADMYNWEVAIFGPPNTHYEGGYFKVrhvsfvtqaRIKFPIDYPYSPPAFRFLTKMWHPNIYENGDV 104
           688*******************************************8633333333379****************************** PP
   S: 82   Clsilk...........eeekWspalsvesvllsiqsllaepnpesplneeaaellkknre 131
           C+sil+           ++e+W+p+++v+++lls++sll+epn+ sp+n++a+ +++k+r 
   Q: 105  CISILHppvddpqsgelPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWRD 165
           *****999999999*9*****************************************9986 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MAQHDHTHVA SSQKALMLEM KSLQEQPVEG FKITLVNEAD MYNWEVAIFG PPNTHYEGGY 60
FKVRHVSFVT QARIKFPIDY PYSPPAFRFL TKMWHPNIYE NGDVCISILH PPVDDPQSGE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGCAAC ACGACCACAC TCATGTAGCC AGTTCACAGA AAGCACTCAT GCTGGAAATG 60
AAGAGCCTCC AGGAGCAGCC TGTCGAGGGA TTCAAAATAA CACTGGTGAA CGAGGCTGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001600	Ailuropoda melanoleuca	84.47	9.00e-104	369.00
IUUC-Bta-012516	Bos taurus	83.98	3.00e-103	367.00
IUUC-Fca-035832	Felis catus	91.67	5.00e-78	283.00
IUUC-Gmo-039414	Gadus morhua	89.72	1.00e-112	398.00
IUUC-Gac-042485	Gasterosteus aculeatus	90.65	3.00e-113	400.00
IUUC-Lch-049845	Latimeria chalumnae	88.32	1.00e-110	392.00
IUUC-Loc-052932	Lepisosteus oculatus	89.25	1.00e-110	392.00
IUUC-Mga-060075	Meleagris gallopavo	80.75	5.00e-107	380.00
IUUC-Mpu-066009	Mustela putorius furo	84.47	2.00e-103	368.00
IUUC-Opr-070826	Ochotona princeps	76.34	3.00e-92	330.00
IUUC-Ont-071745	Oreochromis niloticus	91.12	7.00e-114	402.00
IUUC-Oan-073287	Ornithorhynchus anatinus	77.92	9.00e-104	369.00
IUUC-Ola-086976	Oryzias latipes	91.59	2.00e-115	407.00
IUUC-Oga-088845	Otolemur garnettii	84.47	1.00e-103	369.00
IUUC-Pan-092577	Papio anubis	84.47	2.00e-103	368.00
IUUC-Psi-093039	Pelodiscus sinensis	85.39	4.00e-82	296.00
IUUC-Pfo-096435	Poecilia formosa	91.59	4.00e-115	407.00
IUUC-Pca-100169	Procavia capensis	80.71	1.00e-61	228.00
IUUC-Pva-102875	Pteropus vampyrus	91.61	3.00e-77	280.00
IUUC-Ssc-115699	Sus scrofa	80.61	2.00e-76	278.00
IUUC-Tni-120271	Tetraodon nigroviridis	92.99	5.00e-115	406.00
IUUC-Xtr-132285	Xenopus tropicalis	81.17	2.00e-106	378.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence