iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000007875.2	ENSCJAT00000015408.1	ENSCJAP00000014610.1
ENSCJAG00000007875.2	ENSCJAT00000055080.1	ENSCJAP00000045268.1
ENSCJAG00000007875.2	ENSCJAT00000015402.2	ENSCJAP00000014605.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.90e-55	186.4	9	140
UBD/UBC-like/UBD_UBC	2.70e-81	271.5	9	143

Active Site

Position(s)	Description	Evidence
86	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 4    kelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekW 92
           +el++l++dpp+++sa+pv + dl++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+tki+hPn+++nG++Cl+il+  ++W
   Q: 9    EELTDLQRDPPAQCSAGPVGD-DLFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILR--SQW 94
           79*******************.9************************************************************9..*** PP
   S: 93   spalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           spal+v++vllsi+sll++pnp++pl  e+a+++k++re+y++ +r
   Q: 95   SPALTVSKVLLSICSLLCDPNPDDPLVPEVAHTYKADREKYNRLAR 140
           ******************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 4    kelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsaa 92
            el dl+rd++aq+sa++v+ddlf+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+tkiyhpninsngsicldilrsqws+a
   Q: 9    EELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILRSQWSPA 97
           79*************************************************************************************** PP
   S: 93   ltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           lt+skvlls+csll+d++pddplv+e+a+ yk+d+eky+r arewt
   Q: 98   LTVSKVLLSICSLLCDPNPDDPLVPEVAHTYKADREKYNRLAREWT 143
           *********************************************8 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

RVIGMVVGEE LTDLQRDPPA QCSAGPVGDD LFHWQATIMG PNDSPYQGGV FFLTIHFPTD 60
YPFKPPKVAF TTKIYHPNIN SNGSICLDIL RSQWSPALTV SKVLLSICSL LCDPNPDDPL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCAGCTCGC TGGCTGCTGA CCCGGCAGCG GGCCGCCTCA GGCAGCCCCG GCCGGGCCGC 60
CCGGGTTCCG GGCAGCGGGG CAGGATGGCG CTAAAGCGGA TCCAGAAGGT ACGCACTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0070979--P:protein K11-linked ubiquitination
GO:0044314--P:protein K27-linked ubiquitination
GO:0035519--P:protein K29-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0085020--P:protein K6-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Afl-008709	Aspergillus flavus	78.47	5.00e-70	258.00
IUUC-Cpo-021897	Cavia porcellus	97.18	7.00e-81	291.00
IUUC-Csa-023377	Chlorocebus sabaeus	97.86	9.00e-81	292.00
IUUC-Dre-028686	Danio rerio	96.48	2.00e-81	293.00
IUUC-Dor-030323	Dipodomys ordii	96.48	2.00e-81	293.00
IUUC-Eca-033231	Equus caballus	99.28	5.00e-81	292.00
IUUC-Gac-042534	Gasterosteus aculeatus	92.09	1.00e-75	275.00
IUUC-Ggo-045361	Gorilla gorilla	97.18	1.00e-81	295.00
IUUC-Hsa-045934	Homo sapiens	97.18	1.00e-81	295.00
IUUC-Loc-052838	Lepisosteus oculatus	97.18	1.00e-81	295.00
IUUC-Mcc-055421	Macaca mulatta	97.18	1.00e-81	295.00
IUUC-Mmr-061446	Microcebus murinus	96.40	2.00e-79	286.00
IUUC-Mdo-062413	Monodelphis domestica	98.56	1.00e-80	290.00
IUUC-Nle-069715	Nomascus leucogenys	97.18	1.00e-81	295.00
IUUC-Oan-073026	Ornithorhynchus anatinus	97.87	2.00e-81	294.00
IUUC-Ocu-073914	Oryctolagus cuniculus	91.84	5.00e-80	289.00
IUUC-Ola-087515	Oryzias latipes	94.37	6.00e-80	288.00
IUUC-Pan-092614	Papio anubis	99.28	6.00e-81	292.00
IUUC-Pfo-096867	Poecilia formosa	94.37	6.00e-80	288.00
IUUC-Pab-098760	Pongo abelii	96.48	4.00e-81	293.00
IUUC-Ssc-115391	Sus scrofa	97.18	1.00e-81	295.00
IUUC-Tsy-118832	Tarsius syrichta	95.07	5.00e-79	286.00
IUUC-Tbe-128122	Tupaia belangeri	95.97	6.00e-61	225.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence