iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133797

Ensembl Protein ID

ENSXMAP00000004380.1

UniProt Accession

M3ZQ87; M3ZQ87_XIPMA

Genbank Protein ID

ENSXMAP00000004380

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01006390

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000004333.1	ENSXMAT00000004385.1	ENSXMAP00000004380.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.40e-136	454.6	649	980

Active Site

Position(s)	Description	Evidence
950	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++ lk+rl++ef+ E+gld+gGv+re+++llske++np++glf+ys++d++tlq+np+sgl+n++hl++F+f+Gr+ g+a+++g+lld 
   Q: 649  PDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVFHGKLLDG 737
           57899************************************************************************************ PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvve 179
           ++ ++fyk++lgk++sl+d+e+vd+e+y+slk+i+en   d +e  ldl+f+++e+++g+t++++Lkp+G+++ VtneNk+eY++lv++
   Q: 738  FFIRPFYKMMLGKQISLKDMESVDSEYYNSLKWILEN---DPTE--LDLRFCIDEDNFGQTYQVDLKPSGSDMVVTNENKKEYIDLVIQ 821
           ***********************************99...6666..7****************************************** PP
   S: 180  yrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFv 268
           +r+ +++++q++af eGf+e+ip++l+++F+e+elell+cG  ++dv+d++++t yk+gy +++p+iqwFw+v+  +++e+r ++LqFv
   Q: 822  WRFVNRVQKQMNAFLEGFTELIPIDLIKIFDENELELLMCGLGDVDVNDWRQHTVYKNGYCPNHPVIQWFWKVVLLMDAEKRIRLLQFV 910
           ***************************************************************************************** PP
   S: 269  TgssrlPlgGfaelk....prlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
           Tg+sr+P++Gfael     p+lf+i++++++d+lP+++TCfn+L+LP Y+s e l+ekLl+A+e+++gFe
   Q: 911  TGTSRVPMNGFAELYgsngPQLFTIEQWGTPDKLPRAHTCFNRLDLPSYESFEDLREKLLMAVENAQGFE 980
           *********************************************************************8 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MATNYEPIYG LSEDEHDTRV LRVKVIAGID LAKKDIIGAS DPYVKLSLYV ADENKELGLV 60
QTKTIKKTLN PKWNEEFYFR VCPQNHRLLF EVFDENRLTR DDFLGQVDVP LSHLPTEDPA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAACGA ATTACGAGCC TATATATGGA CTTTCAGAGG ACGAGGTAAG CTTGAATTGT 60
AATTAAGGTG TTATTGAAAT GCAGAATGGA GTCGTTGGGT ATTATGAGGG GCAGGGAGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

PRINTS

PR00360--C2DOMAIN

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001314	Ailuropoda melanoleuca	80.10	0.00e+00	1447.00
IUUC-Apl-003893	Anas platyrhynchos	81.26	0.00e+00	1491.00
IUUC-Aca-004744	Anolis carolinensis	78.07	0.00e+00	1431.00
IUUC-Ago-007742	Ashbya gossypii	49.58	3.00e-165	575.00
IUUC-Acl-008273	Aspergillus clavatus	50.08	5.00e-166	578.00
IUUC-Afl-008713	Aspergillus flavus	50.17	3.00e-165	575.00
IUUC-Afu-009103	Aspergillus fumigatus	49.83	3.00e-167	582.00
IUUC-Ani-009259	Aspergillus nidulans	49.43	3.00e-165	575.00
IUUC-Ang-009738	Aspergillus niger	50.08	4.00e-164	572.00
IUUC-Aor-010053	Aspergillus oryzae	58.05	4.00e-102	363.00
IUUC-Ate-010529	Aspergillus terreus	50.17	2.00e-166	579.00
IUUC-Ame-010810	Astyanax mexicanus	90.71	0.00e+00	1083.00
IUUC-Bgr-012148	Blumeria graminis	48.34	6.00e-157	548.00
IUUC-Bta-012679	Bos taurus	80.47	0.00e+00	1347.00
IUUC-Bci-013785	Botrytis cinerea	48.41	3.00e-159	555.00
IUUC-Cel-018564	Caenorhabditis elegans	50.91	2.00e-180	625.00
IUUC-Cja-018732	Callithrix jacchus	81.31	0.00e+00	1536.00
IUUC-Cfa-021226	Canis familiaris	81.36	0.00e+00	1529.00
IUUC-Cpo-021671	Cavia porcellus	80.37	0.00e+00	1490.00
IUUC-Csa-023344	Chlorocebus sabaeus	79.62	0.00e+00	1521.00
IUUC-Cho-024832	Choloepus hoffmanni	94.89	0.00e+00	719.00
IUUC-Csv-026098	Ciona savignyi	59.22	0.00e+00	657.00
IUUC-Cgl-026642	Colletotrichum gloeosporioides	48.01	4.00e-157	548.00
IUUC-Cne-026849	Cryptococcus neoformans	49.25	6.00e-162	564.00
IUUC-Dre-027770	Danio rerio	85.59	0.00e+00	1570.00
IUUC-Dno-029466	Dasypus novemcinctus	80.87	0.00e+00	1533.00
IUUC-Dor-030138	Dipodomys ordii	78.19	0.00e+00	1400.00
IUUC-Dse-031241	Dothistroma septosporum	48.85	1.00e-161	563.00
IUUC-Dme-032166	Drosophila melanogaster	68.76	0.00e+00	725.00
IUUC-Ete-033145	Echinops telfairi	75.56	0.00e+00	1090.00
IUUC-Eca-033445	Equus caballus	80.88	0.00e+00	1343.00
IUUC-Eeu-035247	Erinaceus europaeus	74.32	0.00e+00	1288.00
IUUC-Fca-035489	Felis catus	78.60	0.00e+00	1290.00
IUUC-Fal-037604	Ficedula albicollis	78.68	0.00e+00	1512.00
IUUC-Fox-037774	Fusarium oxysporum	48.76	2.00e-159	556.00
IUUC-Fso-038393	Fusarium solani	47.52	2.00e-157	549.00
IUUC-Gmo-039674	Gadus morhua	86.21	0.00e+00	1584.00
IUUC-Ggr-040107	Gaeumannomyces graminis	48.67	1.00e-159	557.00
IUUC-Gga-040703	Gallus gallus	80.87	0.00e+00	1537.00
IUUC-Gac-042020	Gasterosteus aculeatus	92.89	0.00e+00	1694.00
IUUC-Ggo-045332	Gorilla gorilla	80.32	0.00e+00	1462.00
IUUC-Hsa-045968	Homo sapiens	81.28	0.00e+00	1533.00
IUUC-Itr-048383	Ictidomys tridecemlineatus	65.43	0.00e+00	828.00
IUUC-Kpa-049273	Komagataella pastoris	49.58	2.00e-165	576.00
IUUC-Lch-050443	Latimeria chalumnae	81.19	0.00e+00	1377.00
IUUC-Loc-052662	Lepisosteus oculatus	82.13	0.00e+00	1501.00
IUUC-Laf-053850	Loxodonta africana	80.33	0.00e+00	1502.00
IUUC-Mcc-055821	Macaca mulatta	81.55	0.00e+00	1514.00
IUUC-Meu-056712	Macropus eugenii	63.12	3.00e-170	592.00
IUUC-Mor-057097	Magnaporthe oryzae	48.00	4.00e-159	555.00
IUUC-Mpo-057442	Magnaporthe poae	52.47	4.00e-148	519.00
IUUC-Mla-058996	Melampsora laricipopulina	48.60	6.00e-157	548.00
IUUC-Mga-059362	Meleagris gallopavo	64.45	0.00e+00	1169.00
IUUC-Mvi-060395	Microbotryum violaceum	55.14	1.00e-154	540.00
IUUC-Mmr-060798	Microcebus murinus	77.82	0.00e+00	1407.00
IUUC-Mdo-062173	Monodelphis domestica	79.44	0.00e+00	1537.00
IUUC-Mmu-064136	Mus musculus	80.93	0.00e+00	1514.00
IUUC-Mpu-066765	Mustela putorius furo	82.01	0.00e+00	1507.00
IUUC-Mlu-067565	Myotis lucifugus	80.29	0.00e+00	1345.00
IUUC-Nfi-068427	Neosartorya fischeri	50.00	2.00e-167	583.00
IUUC-Ncr-068918	Neurospora crassa	48.58	9.00e-159	554.00
IUUC-Nle-069070	Nomascus leucogenys	78.36	0.00e+00	1466.00
IUUC-Opr-071044	Ochotona princeps	85.69	0.00e+00	1097.00
IUUC-Ont-072044	Oreochromis niloticus	90.83	0.00e+00	1740.00
IUUC-Oan-073032	Ornithorhynchus anatinus	76.96	0.00e+00	1229.00
IUUC-Ocu-074160	Oryctolagus cuniculus	79.77	0.00e+00	1470.00
IUUC-Ola-087467	Oryzias latipes	93.22	0.00e+00	1744.00
IUUC-Oga-088460	Otolemur garnettii	79.26	0.00e+00	1332.00
IUUC-Oar-090198	Ovis aries	81.19	0.00e+00	1491.00
IUUC-Ptr-090939	Pan troglodytes	81.28	0.00e+00	1533.00
IUUC-Pan-092284	Papio anubis	81.07	0.00e+00	1530.00
IUUC-Psi-093645	Pelodiscus sinensis	80.75	0.00e+00	1533.00
IUUC-Pma-094364	Petromyzon marinus	81.84	0.00e+00	859.00
IUUC-Pno-095118	Phaeosphaeria nodorum	47.21	1.00e-162	567.00
IUUC-Pfo-096768	Poecilia formosa	99.82	0.00e+00	1033.00
IUUC-Pab-098088	Pongo abelii	81.47	0.00e+00	1518.00
IUUC-Pca-100714	Procavia capensis	71.66	0.00e+00	995.00
IUUC-Pva-102354	Pteropus vampyrus	80.04	0.00e+00	1442.00
IUUC-Pgr-103620	Puccinia graminis	53.94	2.00e-150	526.00
IUUC-Ptt-103806	Puccinia triticina	54.59	4.00e-127	448.00
IUUC-Pte-104016	Pyrenophora teres	48.34	1.00e-162	567.00
IUUC-Pyt-104550	Pyrenophora triticirepentis	48.34	1.00e-162	567.00
IUUC-Rno-105318	Rattus norvegicus	80.18	0.00e+00	1477.00
IUUC-Sce-106289	Saccharomyces cerevisiae	50.08	7.00e-167	581.00
IUUC-Sha-107482	Sarcophilus harrisii	80.54	0.00e+00	1372.00
IUUC-Sja-107786	Schizosaccharomyces japonicus	47.75	1.00e-154	540.00
IUUC-Spo-108171	Schizosaccharomyces pombe	49.08	2.00e-162	566.00
IUUC-Ssl-108514	Sclerotinia sclerotiorum	48.92	1.00e-159	556.00
IUUC-Ssc-115950	Sus scrofa	64.20	0.00e+00	1067.00
IUUC-Tgu-117130	Taeniopygia guttata	80.78	0.00e+00	1519.00
IUUC-Tru-118610	Takifugu rubripes	92.49	0.00e+00	1747.00
IUUC-Tsy-119492	Tarsius syrichta	77.21	0.00e+00	1369.00
IUUC-Tni-120113	Tetraodon nigroviridis	87.28	0.00e+00	1606.00
IUUC-Tre-122203	Trichoderma reesei	48.09	1.00e-155	543.00
IUUC-Tvi-122595	Trichoderma virens	48.10	1.00e-158	553.00
IUUC-Ttr-128235	Tursiops truncatus	90.29	0.00e+00	1021.00
IUUC-Uma-129332	Ustilago maydis	53.10	7.00e-144	504.00
IUUC-Vda-129753	Verticillium dahliae	47.93	8.00e-158	550.00
IUUC-Xtr-132859	Xenopus tropicalis	81.22	0.00e+00	1509.00
IUUC-Yli-134668	Yarrowia lipolytica	47.56	9.00e-165	574.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence