iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033545

Ensembl Protein ID

ENSECAP00000014483.1

UniProt Accession

F6XBS8; F6XBS8_HORSE

Protein Name

Uncharacterized protein

Gene Name

ARHGAP10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000016629.1	ENSECAT00000017805.1	ENSECAP00000014483.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.40e-11	43.1	678	732

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +k ++ y+ ea+++ eL+++ G + + + +++ + gWl+g  +l+gkrGl+P+n+v+ 
   Q: 678  RKARAVYPCEAEHSSELSFEIGAIFEDV-QTSREPGWLEG--TLNGKRGLIPQNYVKL 732
           57789***********************.***********..8*************85 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

LSAAQRKFAH SLRDFKFEFI GDAETDDERC IDASLREFSN FLKNLEEQRE IMALSVTETL 60
IKPLEKFRKE QLGAVKEEKK KFDKETEKNY SLIDKHLNLS AKKKDSHLQE ADIQVEQNRQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGTCTTTCA GCAGCCCAGC GGAAGTTTGC TCATTCACTC AGAGACTTTA AATTTGAGTT 60
TATTGGGGAT GCGGAGACGG ATGATGAACG CTGCATAGGT ATGTAAAGAT GAGGTTTTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0343--GTPase activation
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR008936--Rho_GTPase_activation_prot
IPR000198--RhoGAP_dom
IPR001452--SH3_domain

PROSITE

PS50003--PH_DOMAIN
PS50238--RHOGAP
PS50002--SH3

Pfam

PF00169--PH
PF00620--RhoGAP
PF14604--SH3_9

SMART

SM00233--PH
SM00324--RhoGAP
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:0007010--P:cytoskeleton organization
GO:0043066--P:negative regulation of apoptotic process
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001253	Ailuropoda melanoleuca	93.73	0.00e+00	1362.00
IUUC-Apl-003297	Anas platyrhynchos	80.38	0.00e+00	1151.00
IUUC-Aca-005285	Anolis carolinensis	78.31	0.00e+00	1142.00
IUUC-Bta-012379	Bos taurus	92.10	0.00e+00	1294.00
IUUC-Cja-019182	Callithrix jacchus	93.32	0.00e+00	1348.00
IUUC-Cfa-021141	Canis familiaris	93.73	0.00e+00	1352.00
IUUC-Csa-023847	Chlorocebus sabaeus	93.46	0.00e+00	1348.00
IUUC-Dre-027525	Danio rerio	59.59	0.00e+00	797.00
IUUC-Dno-029215	Dasypus novemcinctus	86.02	0.00e+00	942.00
IUUC-Dor-030308	Dipodomys ordii	82.97	0.00e+00	1172.00
IUUC-Ete-032666	Echinops telfairi	79.13	0.00e+00	773.00
IUUC-Fca-036457	Felis catus	93.87	0.00e+00	1358.00
IUUC-Fal-036703	Ficedula albicollis	80.38	0.00e+00	1155.00
IUUC-Gga-040830	Gallus gallus	79.02	0.00e+00	1164.00
IUUC-Gac-041728	Gasterosteus aculeatus	56.11	0.00e+00	757.00
IUUC-Ggo-044569	Gorilla gorilla	91.01	0.00e+00	1285.00
IUUC-Hsa-045658	Homo sapiens	93.32	0.00e+00	1302.00
IUUC-Loc-051740	Lepisosteus oculatus	63.92	0.00e+00	899.00
IUUC-Laf-053641	Loxodonta africana	91.01	0.00e+00	1300.00
IUUC-Mcc-055152	Macaca mulatta	93.19	0.00e+00	1350.00
IUUC-Mmr-061434	Microcebus murinus	94.55	0.00e+00	1367.00
IUUC-Mdo-062864	Monodelphis domestica	87.60	0.00e+00	1273.00
IUUC-Mmu-064061	Mus musculus	91.28	0.00e+00	1327.00
IUUC-Mlu-067375	Myotis lucifugus	93.32	0.00e+00	1338.00
IUUC-Nle-069319	Nomascus leucogenys	90.27	0.00e+00	741.00
IUUC-Ont-071443	Oreochromis niloticus	60.76	0.00e+00	835.00
IUUC-Oan-072978	Ornithorhynchus anatinus	84.43	0.00e+00	1116.00
IUUC-Ocu-074591	Oryctolagus cuniculus	88.42	0.00e+00	1263.00
IUUC-Oga-088922	Otolemur garnettii	89.89	0.00e+00	653.00
IUUC-Oar-089531	Ovis aries	92.37	0.00e+00	1312.00
IUUC-Ptr-091149	Pan troglodytes	91.96	0.00e+00	1296.00
IUUC-Pan-092591	Papio anubis	94.14	0.00e+00	1367.00
IUUC-Pma-094731	Petromyzon marinus	31.76	2.00e-19	92.40
IUUC-Pfo-097265	Poecilia formosa	66.19	0.00e+00	732.00
IUUC-Pab-097780	Pongo abelii	92.92	0.00e+00	1299.00
IUUC-Rno-104991	Rattus norvegicus	90.60	0.00e+00	1321.00
IUUC-Sha-107629	Sarcophilus harrisii	84.71	0.00e+00	1116.00
IUUC-Ssc-115511	Sus scrofa	80.52	0.00e+00	742.00
IUUC-Tgu-117458	Taeniopygia guttata	79.16	0.00e+00	1136.00
IUUC-Tru-117724	Takifugu rubripes	62.13	0.00e+00	683.00
IUUC-Tbe-128126	Tupaia belangeri	26.11	2.00e-06	47.80
IUUC-Ttr-129045	Tursiops truncatus	91.01	0.00e+00	1287.00
IUUC-Xtr-132112	Xenopus tropicalis	69.35	0.00e+00	990.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence