iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000017119.3	ENSMMUT00000043390.2	ENSMMUP00000036387.2
ENSMMUG00000017119.3	ENSMMUT00000043389.2	ENSMMUP00000036386.1
ENSMMUG00000017119.3	ENSMMUT00000024070.3	ENSMMUP00000022525.3
ENSMMUG00000017119.3	ENSMMUT00000066279.1	ENSMMUP00000051917.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.70e-24	84.5	366	397
UBD/Beta-Prp	1.10e-44	153.9	279	487

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlr 31
           gHtd vt+  f  ++ +vsGsdD t+kvWDl+
   Q: 366  GHTDTVTSAVFtVGDNVVSGSDDRTVKVWDLK 397
           8*******99*733669*************96 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc..vhtlkgh 93
           ++h++v+ + ++  ++++ +t+s+d+t  ++dv+t  l++sl gh++e t ++ +p++ + vt+s+D t ++wd++++++  v +++gh
   Q: 279  KSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIhsVNVFQGH 367
           456667777999999999**********************************************************665422889**** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltggh 179
           +d+v+s  f   gd +vsGs+drt++vwdl++     +t +  + ++n ++v   +++++  +++r+vrl+d+   + ++l r  ++gh
   Q: 368  TDTVTSAVFTV-GDNVVSGSDDRTVKVWDLKNMRSPIATIRTDS-AINRINVCVGQKIIALPHDNRQVRLFDMsgvRLARLPRSSRQGH 454
           ******99999.********************988874555555.55555555558*****************555555555555777* PP
   S: 180  tdsvyslsfdsng..kelvsgsldgtvklwdlq 210
            ++v + +++++     l +++ d++ + w++ 
   Q: 455  RRMVCCSAWSEDHpvCNLFTCGFDRQAIGWNIN 487
           ************9888899***********986 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MPTESASCST ARQAKQKRKS HSLSIRRTNS SEQERTGLPR DMLEGQDSKL PSSVRSTLLE 60
LFGQIEREFE NLYIENLELR REIDTLNERL AAEGQAIDGA ELSKGQLKTK ASHSTSQLSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCGCAGGG AACAGCTGAT TCTGTTTTTC CTTCCCAGCC AATGGTGATC AAAAGCTTCA 60
GGACGCGGGT GAGTCACTGC GGAGGAGCCG AACACTGACC GCGCCGTCCC CGCCAGGCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001249	Ailuropoda melanoleuca	96.17	0.00e+00	959.00
IUUC-Apl-003647	Anas platyrhynchos	94.55	0.00e+00	945.00
IUUC-Aca-004759	Anolis carolinensis	93.54	0.00e+00	952.00
IUUC-Ame-011103	Astyanax mexicanus	56.69	9.00e-145	506.00
IUUC-Bta-012718	Bos taurus	95.77	0.00e+00	953.00
IUUC-Cel-018499	Caenorhabditis elegans	42.61	2.00e-96	346.00
IUUC-Cja-019492	Callithrix jacchus	99.19	0.00e+00	1016.00
IUUC-Cfa-020199	Canis familiaris	95.77	0.00e+00	988.00
IUUC-Cpo-022500	Cavia porcellus	91.33	0.00e+00	941.00
IUUC-Csa-023567	Chlorocebus sabaeus	100.00	0.00e+00	1022.00
IUUC-Cho-025071	Choloepus hoffmanni	69.09	0.00e+00	647.00
IUUC-Cin-025460	Ciona intestinalis	45.44	9.00e-104	370.00
IUUC-Csv-026042	Ciona savignyi	46.09	5.00e-108	384.00
IUUC-Dre-028214	Danio rerio	84.24	0.00e+00	859.00
IUUC-Dno-029826	Dasypus novemcinctus	96.39	0.00e+00	824.00
IUUC-Dor-030967	Dipodomys ordii	97.79	0.00e+00	902.00
IUUC-Dme-031936	Drosophila melanogaster	49.47	1.00e-119	422.00
IUUC-Ete-032452	Echinops telfairi	93.94	0.00e+00	954.00
IUUC-Eca-033278	Equus caballus	96.57	0.00e+00	991.00
IUUC-Eeu-034592	Erinaceus europaeus	84.44	0.00e+00	835.00
IUUC-Fca-036431	Felis catus	96.78	0.00e+00	993.00
IUUC-Fal-037149	Ficedula albicollis	93.33	0.00e+00	939.00
IUUC-Gmo-038476	Gadus morhua	79.40	0.00e+00	775.00
IUUC-Gga-041099	Gallus gallus	94.14	0.00e+00	944.00
IUUC-Gac-042374	Gasterosteus aculeatus	82.57	0.00e+00	820.00
IUUC-Ggo-044683	Gorilla gorilla	91.52	0.00e+00	922.00
IUUC-Hsa-046658	Homo sapiens	99.19	0.00e+00	1012.00
IUUC-Itr-048870	Ictidomys tridecemlineatus	98.24	0.00e+00	928.00
IUUC-Lch-050571	Latimeria chalumnae	84.79	0.00e+00	886.00
IUUC-Loc-052652	Lepisosteus oculatus	82.22	0.00e+00	861.00
IUUC-Laf-053712	Loxodonta africana	95.39	0.00e+00	977.00
IUUC-Meu-056324	Macropus eugenii	90.51	0.00e+00	893.00
IUUC-Mga-060114	Meleagris gallopavo	93.95	0.00e+00	939.00
IUUC-Mmr-061176	Microcebus murinus	97.78	0.00e+00	1004.00
IUUC-Mdo-061888	Monodelphis domestica	94.96	0.00e+00	926.00
IUUC-Mmu-063977	Mus musculus	97.38	0.00e+00	1002.00
IUUC-Mpu-066220	Mustela putorius furo	83.42	0.00e+00	627.00
IUUC-Mlu-068155	Myotis lucifugus	96.77	0.00e+00	996.00
IUUC-Nle-069964	Nomascus leucogenys	99.39	0.00e+00	1018.00
IUUC-Opr-070925	Ochotona princeps	96.36	2.00e-152	531.00
IUUC-Ont-071317	Oreochromis niloticus	86.29	0.00e+00	840.00
IUUC-Oan-072952	Ornithorhynchus anatinus	94.76	0.00e+00	948.00
IUUC-Ocu-073913	Oryctolagus cuniculus	97.58	0.00e+00	1004.00
IUUC-Ola-087024	Oryzias latipes	84.91	0.00e+00	882.00
IUUC-Oga-087945	Otolemur garnettii	97.78	0.00e+00	1006.00
IUUC-Oar-089854	Ovis aries	96.17	0.00e+00	945.00
IUUC-Ptr-091486	Pan troglodytes	99.39	0.00e+00	1013.00
IUUC-Pan-091738	Papio anubis	100.00	0.00e+00	1022.00
IUUC-Psi-093953	Pelodiscus sinensis	93.35	0.00e+00	935.00
IUUC-Pma-094560	Petromyzon marinus	76.13	0.00e+00	773.00
IUUC-Pfo-097222	Poecilia formosa	84.65	0.00e+00	832.00
IUUC-Pab-098778	Pongo abelii	94.14	0.00e+00	948.00
IUUC-Pca-100852	Procavia capensis	93.13	0.00e+00	937.00
IUUC-Pva-103130	Pteropus vampyrus	95.45	2.00e-134	472.00
IUUC-Rno-105848	Rattus norvegicus	88.31	0.00e+00	885.00
IUUC-Sha-106750	Sarcophilus harrisii	95.16	0.00e+00	956.00
IUUC-Sar-113749	Sorex araneus	88.28	0.00e+00	886.00
IUUC-Ssc-115691	Sus scrofa	94.34	0.00e+00	940.00
IUUC-Tgu-117365	Taeniopygia guttata	92.73	0.00e+00	894.00
IUUC-Tru-117595	Takifugu rubripes	84.48	0.00e+00	831.00
IUUC-Tsy-118973	Tarsius syrichta	77.69	6.00e-156	543.00
IUUC-Tni-120545	Tetraodon nigroviridis	83.73	0.00e+00	865.00
IUUC-Tbe-127976	Tupaia belangeri	72.12	0.00e+00	696.00
IUUC-Ttr-128472	Tursiops truncatus	93.94	0.00e+00	950.00
IUUC-Xtr-132621	Xenopus tropicalis	91.72	0.00e+00	908.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence