iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000004958.5	ENSGALT00000060296.1	ENSGALP00000045102.1
ENSGALG00000004958.5	ENSGALT00000048434.1	ENSGALP00000050884.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.50e-11	43.2	254	310

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +++kv +ly+y + n  +L+l+kG+  l++  ee    W+k+ ++ +g++G +P+n+v+ 
   Q: 254  EMKKVVALYNYVPMNVQDLQLQKGEEYLIL--EESHLPWWKA-RDKNGREGYIPSNYVTA 310
           689**************************9..888999****.5**************86 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MAGWGEDTVR TCPFCPPLLG VAQLLQHKQP REHGEEAAGV ADMASIILES IFLKRSQQKK 60
KTSPLNFKKR LFLLTESKLS YYEYDFERGR RGSKKGSVDI EKITCVETVV PENNPPPERQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTGCGCTGT GTCCCCGCAG CCGCCCCGAC TCGCGGTGCT GGGCCGCTCG GGGCAGGCGT 60
GGGGCAGCAG GCACAGCACA GCACAGCACT GTCCATCTGG GGCAGCTGGG AGGGCTCGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
IPR001562--Znf_Btk_motif

PROSITE

PS50003--PH_DOMAIN
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3
PS51113--ZF_BTK

Pfam

PF00779--BTK
PF00169--PH
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00402--TECBTKDOMAIN
PR00109--TYRKINASE

SMART

SM00107--BTK
SM00233--PH
SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005622--C:intracellular
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0035556--P:intracellular signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001365	Ailuropoda melanoleuca	85.13	0.00e+00	1157.00
IUUC-Apl-003907	Anas platyrhynchos	95.71	0.00e+00	1256.00
IUUC-Aca-004978	Anolis carolinensis	78.33	0.00e+00	1073.00
IUUC-Ame-010694	Astyanax mexicanus	56.98	1.00e-151	529.00
IUUC-Bta-012467	Bos taurus	84.83	0.00e+00	1154.00
IUUC-Cja-018841	Callithrix jacchus	84.52	0.00e+00	1147.00
IUUC-Cfa-020983	Canis familiaris	84.83	0.00e+00	1129.00
IUUC-Cpo-021307	Cavia porcellus	85.28	0.00e+00	1158.00
IUUC-Csa-023508	Chlorocebus sabaeus	83.90	0.00e+00	843.00
IUUC-Dre-028544	Danio rerio	59.31	6.00e-147	513.00
IUUC-Dno-029828	Dasypus novemcinctus	83.59	0.00e+00	1130.00
IUUC-Dor-030102	Dipodomys ordii	76.63	0.00e+00	936.00
IUUC-Ete-032981	Echinops telfairi	77.85	0.00e+00	1031.00
IUUC-Eca-033594	Equus caballus	84.83	0.00e+00	1154.00
IUUC-Eeu-035281	Erinaceus europaeus	82.17	0.00e+00	906.00
IUUC-Fca-035495	Felis catus	84.22	0.00e+00	1122.00
IUUC-Fal-036719	Ficedula albicollis	95.43	0.00e+00	1286.00
IUUC-Gac-042383	Gasterosteus aculeatus	49.24	2.00e-125	442.00
IUUC-Hsa-045931	Homo sapiens	80.91	0.00e+00	1136.00
IUUC-Itr-048061	Ictidomys tridecemlineatus	84.98	0.00e+00	1155.00
IUUC-Lch-049868	Latimeria chalumnae	74.50	0.00e+00	963.00
IUUC-Loc-052730	Lepisosteus oculatus	58.20	7.00e-161	560.00
IUUC-Laf-053516	Loxodonta africana	85.63	0.00e+00	1171.00
IUUC-Mcc-054795	Macaca mulatta	80.63	0.00e+00	1135.00
IUUC-Meu-056157	Macropus eugenii	76.02	0.00e+00	988.00
IUUC-Mga-059529	Meleagris gallopavo	99.45	0.00e+00	1121.00
IUUC-Mmr-060824	Microcebus murinus	77.83	0.00e+00	1059.00
IUUC-Mdo-063036	Monodelphis domestica	86.56	0.00e+00	1146.00
IUUC-Mmu-064047	Mus musculus	84.52	0.00e+00	1152.00
IUUC-Mpu-066810	Mustela putorius furo	84.83	0.00e+00	1155.00
IUUC-Mlu-067671	Myotis lucifugus	85.07	0.00e+00	1141.00
IUUC-Nle-069108	Nomascus leucogenys	84.52	0.00e+00	1129.00
IUUC-Opr-070505	Ochotona princeps	68.19	2.00e-173	601.00
IUUC-Ont-072585	Oreochromis niloticus	58.24	3.00e-160	557.00
IUUC-Oan-073495	Ornithorhynchus anatinus	86.15	0.00e+00	1177.00
IUUC-Ocu-074416	Oryctolagus cuniculus	84.67	0.00e+00	1151.00
IUUC-Ola-086938	Oryzias latipes	57.57	5.00e-154	536.00
IUUC-Oga-088995	Otolemur garnettii	83.53	0.00e+00	1119.00
IUUC-Oar-089632	Ovis aries	84.95	0.00e+00	1139.00
IUUC-Ptr-090941	Pan troglodytes	84.52	0.00e+00	1129.00
IUUC-Pan-091900	Papio anubis	82.09	0.00e+00	1087.00
IUUC-Psi-093048	Pelodiscus sinensis	89.23	0.00e+00	1167.00
IUUC-Pfo-096955	Poecilia formosa	58.54	3.00e-160	558.00
IUUC-Pab-097587	Pongo abelii	84.52	0.00e+00	1130.00
IUUC-Pca-100374	Procavia capensis	74.92	2.00e-125	442.00
IUUC-Pva-102583	Pteropus vampyrus	84.83	0.00e+00	1127.00
IUUC-Rno-104868	Rattus norvegicus	81.12	0.00e+00	1071.00
IUUC-Sha-106744	Sarcophilus harrisii	86.19	0.00e+00	1171.00
IUUC-Sar-113041	Sorex araneus	84.07	0.00e+00	1003.00
IUUC-Ssc-115294	Sus scrofa	84.67	0.00e+00	1153.00
IUUC-Tgu-116458	Taeniopygia guttata	54.46	0.00e+00	716.00
IUUC-Tsy-118945	Tarsius syrichta	84.98	0.00e+00	769.00
IUUC-Ttr-128769	Tursiops truncatus	76.93	0.00e+00	1021.00
IUUC-Vpa-130517	Vicugna pacos	79.64	0.00e+00	628.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence