iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000005869.2	ENSLACT00000025708.1	ENSLACP00000023292.1
ENSLACG00000005869.2	ENSLACT00000006672.1	ENSLACP00000006618.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.90e-10	40.8	215	271

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           ++e+v+++yd++a +  +L+l  G+  l+i  ++ d  W+k+ k+ +g +G +P+n+v++
   Q: 215  KEELVIAMYDFQALEHHDLNLVTGEEYLII--QKCDIHWWKA-KDKHGNEGYIPSNYVTE 271
           5789**************************..899*******.7**************86 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MSWARIPQYT ESLKDWVFNG RKNSDQEDEM NSEVILEEVL IKRSQQKKRT SPLNYKERLF 60
VLTKSKLSYY DGRLEKKSKK GSIDIEKVKC VEIVKNDTGL IPCPNKYPFQ VLYDVNTLYI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTCCTCCGG CAGGCAGAGA GCTGCTGACA CTCAGGCATT TCTATAACCT CTCAGGTAAG 60
GTCGATTCCC ATCGCAAATT ACACTGCCTC GGTAGATTAT TAACTGAACA TGAACAGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
IPR001562--Znf_Btk_motif

PROSITE

PS50003--PH_DOMAIN
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3
PS51113--ZF_BTK

Pfam

PF00779--BTK
PF00169--PH
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00402--TECBTKDOMAIN
PR00109--TYRKINASE

SMART

SM00107--BTK
SM00233--PH
SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005622--C:intracellular
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0035556--P:intracellular signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003669	Anas platyrhynchos	71.30	0.00e+00	920.00
IUUC-Ame-010694	Astyanax mexicanus	64.61	7.00e-170	590.00
IUUC-Dre-028544	Danio rerio	70.30	3.00e-171	593.00
IUUC-Fal-036771	Ficedula albicollis	75.51	0.00e+00	968.00
IUUC-Gac-042383	Gasterosteus aculeatus	57.46	1.00e-141	496.00
IUUC-Loc-052730	Lepisosteus oculatus	71.43	0.00e+00	659.00
IUUC-Mga-060196	Meleagris gallopavo	72.47	0.00e+00	916.00
IUUC-Mdo-062054	Monodelphis domestica	72.69	0.00e+00	982.00
IUUC-Mpu-066786	Mustela putorius furo	74.13	0.00e+00	947.00
IUUC-Ont-072585	Oreochromis niloticus	68.62	0.00e+00	633.00
IUUC-Ola-086938	Oryzias latipes	68.04	2.00e-177	614.00
IUUC-Psi-093565	Pelodiscus sinensis	76.11	0.00e+00	971.00
IUUC-Pfo-096955	Poecilia formosa	67.57	0.00e+00	634.00
IUUC-Tgu-116458	Taeniopygia guttata	76.74	0.00e+00	988.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence