iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-116458

Ensembl Protein ID

ENSTGUP00000008388.1

UniProt Accession

H0ZCS7; H0ZCS7_TAEGU

Genbank Protein ID

ENSTGUP00000008388

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

ABQF01011123

Gene Name

TEC

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000008092.1	ENSTGUT00000008476.1	ENSTGUP00000008388.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.20e-11	44.3	182	236

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +e v ++yd+e+++  +L l+kG+  +vi  e++d  W+k+ ++  gk+G +P+n+v+
   Q: 182  EEIVVAMYDFEPTEHHDLRLEKGEEYTVI--EKNDIHWWKA-RDKYGKQGYIPSNYVT 236
           67899************************..99********.5*************96 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MNTTTILQEI LIKRSQQKKR TSPLNYKERL FVLTKSMLTY YEGRAEKKYR KGSVDISRIK 60
CVEVVKSDGI IPCQNKYPFQ VVYDANTLYI FAPSAQSRDQ WVRNLKEEIK NNSNIMVKYH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAATACGA CTACTATCCT ACAAGAGATT TTGATTAAAA GATCACAGCA GAAGAAGAGG 60
ACTTCTCCCT TAAACTACAA AGAGAGACTT TTTGTACTTA CAAAGTCTAT GCTAACATAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
IPR001562--Znf_Btk_motif

PROSITE

PS50003--PH_DOMAIN
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3
PS51113--ZF_BTK

Pfam

PF00779--BTK
PF00169--PH
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00402--TECBTKDOMAIN
PR00109--TYRKINASE

SMART

SM00107--BTK
SM00233--PH
SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005856--C:cytoskeleton
GO:0005886--C:plasma membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0050853--P:B cell receptor signaling pathway
GO:0007229--P:integrin-mediated signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:0010543--P:regulation of platelet activation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001365	Ailuropoda melanoleuca	53.24	0.00e+00	722.00
IUUC-Apl-003669	Anas platyrhynchos	86.70	0.00e+00	1107.00
IUUC-Aca-004978	Anolis carolinensis	50.61	0.00e+00	672.00
IUUC-Ame-010694	Astyanax mexicanus	63.66	3.00e-164	571.00
IUUC-Bta-012467	Bos taurus	53.24	0.00e+00	721.00
IUUC-Cja-018841	Callithrix jacchus	52.94	0.00e+00	718.00
IUUC-Cfa-020983	Canis familiaris	53.24	0.00e+00	717.00
IUUC-Cpo-021307	Cavia porcellus	53.24	0.00e+00	721.00
IUUC-Csa-023508	Chlorocebus sabaeus	60.95	8.00e-172	596.00
IUUC-Dre-028544	Danio rerio	67.08	1.00e-164	572.00
IUUC-Dno-029828	Dasypus novemcinctus	52.57	0.00e+00	702.00
IUUC-Dor-030102	Dipodomys ordii	49.27	1.00e-168	586.00
IUUC-Ete-032981	Echinops telfairi	47.36	1.00e-174	605.00
IUUC-Eca-033594	Equus caballus	52.94	0.00e+00	717.00
IUUC-Eeu-035281	Erinaceus europaeus	48.91	3.00e-149	521.00
IUUC-Fca-035495	Felis catus	53.39	0.00e+00	720.00
IUUC-Fal-036771	Ficedula albicollis	96.67	0.00e+00	1204.00
IUUC-Gga-041193	Gallus gallus	52.87	0.00e+00	711.00
IUUC-Gac-042383	Gasterosteus aculeatus	55.41	8.00e-137	479.00
IUUC-Hsa-045931	Homo sapiens	52.94	0.00e+00	715.00
IUUC-Itr-048061	Ictidomys tridecemlineatus	52.94	0.00e+00	717.00
IUUC-Lch-050516	Latimeria chalumnae	76.74	0.00e+00	971.00
IUUC-Loc-052730	Lepisosteus oculatus	68.40	0.00e+00	640.00
IUUC-Laf-053516	Loxodonta africana	52.93	0.00e+00	716.00
IUUC-Mcc-054795	Macaca mulatta	52.94	0.00e+00	716.00
IUUC-Meu-056157	Macropus eugenii	48.87	2.00e-178	619.00
IUUC-Mga-060196	Meleagris gallopavo	87.96	0.00e+00	1102.00
IUUC-Mmr-060824	Microcebus murinus	53.24	0.00e+00	699.00
IUUC-Mdo-062054	Monodelphis domestica	80.03	0.00e+00	1056.00
IUUC-Mmu-064047	Mus musculus	53.09	0.00e+00	720.00
IUUC-Mpu-066786	Mustela putorius furo	81.43	0.00e+00	1040.00
IUUC-Mlu-067671	Myotis lucifugus	52.32	0.00e+00	692.00
IUUC-Nle-069108	Nomascus leucogenys	52.94	0.00e+00	715.00
IUUC-Opr-070505	Ochotona princeps	48.46	3.00e-118	418.00
IUUC-Ont-072585	Oreochromis niloticus	65.62	7.00e-177	613.00
IUUC-Oan-073495	Ornithorhynchus anatinus	53.41	0.00e+00	712.00
IUUC-Ocu-074416	Oryctolagus cuniculus	52.94	0.00e+00	718.00
IUUC-Ola-086938	Oryzias latipes	65.53	5.00e-172	596.00
IUUC-Oga-088995	Otolemur garnettii	52.85	0.00e+00	716.00
IUUC-Oar-089632	Ovis aries	52.77	0.00e+00	717.00
IUUC-Ptr-090941	Pan troglodytes	52.94	0.00e+00	714.00
IUUC-Pan-091900	Papio anubis	51.58	0.00e+00	684.00
IUUC-Psi-093565	Pelodiscus sinensis	88.47	0.00e+00	1124.00
IUUC-Pfo-096955	Poecilia formosa	65.54	1.00e-178	619.00
IUUC-Pab-097587	Pongo abelii	52.94	0.00e+00	715.00
IUUC-Pva-102583	Pteropus vampyrus	52.64	0.00e+00	694.00
IUUC-Rno-104868	Rattus norvegicus	51.35	0.00e+00	681.00
IUUC-Sha-106744	Sarcophilus harrisii	53.24	0.00e+00	721.00
IUUC-Sar-113041	Sorex araneus	53.47	0.00e+00	644.00
IUUC-Ssc-115294	Sus scrofa	53.09	0.00e+00	720.00
IUUC-Tsy-118945	Tarsius syrichta	61.05	1.00e-160	559.00
IUUC-Ttr-128769	Tursiops truncatus	47.77	0.00e+00	631.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence