iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062020

UUCD1 version

UUC-MoD-00204

Ensembl Protein ID

ENSMODP00000002218.3

UniProt Accession

F6T5M5; F6T5M5_MONDO

Protein Name

Uncharacterized protein

Gene Name

CBLB

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000001816.4	ENSMODT00000002263.3	ENSMODP00000002218.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	8.40e-08	32.8	373	412

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e  kd +++ pCgH+++++Cl +w    ++s ++  CP Cr
   Q: 373  CKICAENDKD-VKIEPCGHLMCTSCLTAW----QESDGQ-GCPFCR 412
           99********.******************....555555.5****8 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MANAMNGRNP GGRGGNPRKG RILGIIDAIQ DAVGPPKQAA ADRRTVEKTW KLMDKVVRLC 60
QNPKLQLKNS PPYILDILPD TYQHLRLILS KYDDNQKLAQ LSENEYFKIY IDSLMKKSKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGGTTGGAA GGAGCTCCCT GCCTTTGGAA TTGCTGTCTT ATCTTACTCT GTGTGCTCCT 60
GTCCCCCACT ACGGCCCCCG CCCCGACGTG CGCGTATATT GTAGCCTCAC GCACTCGCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR015940--UBA
IPR009060--UBA-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS50030--UBA
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING
SM00165--UBA

Gene Ontology

GO:0005829--C:cytosol
GO:0045121--C:membrane raft
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0030971--F:receptor tyrosine kinase binding
GO:0017124--F:SH3 domain binding
GO:0004871--F:signal transducer activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0006508--P:proteolysis

KEGG

mdo:100011932

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001412	Ailuropoda melanoleuca	91.96	0.00e+00	1584.00
IUUC-Apl-004148	Anas platyrhynchos	87.40	0.00e+00	1521.00
IUUC-Aca-005204	Anolis carolinensis	84.30	0.00e+00	1479.00
IUUC-Ame-011919	Astyanax mexicanus	63.22	0.00e+00	1034.00
IUUC-Bta-013044	Bos taurus	92.07	0.00e+00	1578.00
IUUC-Cel-018674	Caenorhabditis elegans	56.92	1.00e-133	469.00
IUUC-Cja-018813	Callithrix jacchus	83.67	0.00e+00	1452.00
IUUC-Cfa-021054	Canis familiaris	91.66	0.00e+00	1638.00
IUUC-Cpo-022514	Cavia porcellus	86.98	0.00e+00	1573.00
IUUC-Csa-024110	Chlorocebus sabaeus	91.86	0.00e+00	1599.00
IUUC-Cho-024886	Choloepus hoffmanni	76.34	0.00e+00	1060.00
IUUC-Cin-025574	Ciona intestinalis	67.89	1.00e-172	599.00
IUUC-Dre-027480	Danio rerio	65.54	0.00e+00	1055.00
IUUC-Dno-028923	Dasypus novemcinctus	91.56	0.00e+00	1573.00
IUUC-Dor-031040	Dipodomys ordii	88.70	0.00e+00	800.00
IUUC-Dme-032213	Drosophila melanogaster	72.43	0.00e+00	639.00
IUUC-Ete-032406	Echinops telfairi	86.73	0.00e+00	1437.00
IUUC-Eca-033849	Equus caballus	91.15	0.00e+00	1604.00
IUUC-Fca-036224	Felis catus	91.67	0.00e+00	1607.00
IUUC-Fal-036860	Ficedula albicollis	98.25	0.00e+00	1017.00
IUUC-Gga-040159	Gallus gallus	84.38	0.00e+00	1485.00
IUUC-Gac-042312	Gasterosteus aculeatus	58.50	0.00e+00	961.00
IUUC-Ggo-045175	Gorilla gorilla	83.65	0.00e+00	1448.00
IUUC-Hsa-046306	Homo sapiens	91.76	0.00e+00	1596.00
IUUC-Lch-049931	Latimeria chalumnae	61.26	0.00e+00	887.00
IUUC-Loc-052524	Lepisosteus oculatus	69.77	0.00e+00	1098.00
IUUC-Laf-053635	Loxodonta africana	87.80	0.00e+00	1518.00
IUUC-Mcc-055536	Macaca mulatta	91.76	0.00e+00	1597.00
IUUC-Meu-056045	Macropus eugenii	83.99	0.00e+00	1346.00
IUUC-Mga-060177	Meleagris gallopavo	94.76	0.00e+00	1132.00
IUUC-Mmr-061088	Microcebus murinus	92.27	0.00e+00	1610.00
IUUC-Mmu-063114	Mus musculus	86.27	0.00e+00	1529.00
IUUC-Mpu-066632	Mustela putorius furo	92.07	0.00e+00	1642.00
IUUC-Mlu-067145	Myotis lucifugus	91.66	0.00e+00	1601.00
IUUC-Ont-072323	Oreochromis niloticus	73.12	0.00e+00	894.00
IUUC-Oan-073165	Ornithorhynchus anatinus	90.36	0.00e+00	1646.00
IUUC-Ocu-074723	Oryctolagus cuniculus	92.07	0.00e+00	1610.00
IUUC-Oga-088021	Otolemur garnettii	91.16	0.00e+00	1587.00
IUUC-Oar-089809	Ovis aries	91.86	0.00e+00	1580.00
IUUC-Ptr-090834	Pan troglodytes	91.66	0.00e+00	1594.00
IUUC-Pan-092225	Papio anubis	91.96	0.00e+00	1602.00
IUUC-Psi-093317	Pelodiscus sinensis	88.45	0.00e+00	1603.00
IUUC-Pma-094249	Petromyzon marinus	77.99	2.00e-127	448.00
IUUC-Pab-097595	Pongo abelii	91.76	0.00e+00	1596.00
IUUC-Pca-100844	Procavia capensis	76.81	0.00e+00	1260.00
IUUC-Pva-103216	Pteropus vampyrus	85.25	0.00e+00	1507.00
IUUC-Rno-105381	Rattus norvegicus	89.93	0.00e+00	1604.00
IUUC-Sha-107574	Sarcophilus harrisii	97.51	0.00e+00	1657.00
IUUC-Sar-113500	Sorex araneus	80.28	0.00e+00	1303.00
IUUC-Ssc-115856	Sus scrofa	90.49	0.00e+00	1362.00
IUUC-Tgu-116866	Taeniopygia guttata	86.75	0.00e+00	1518.00
IUUC-Tru-118579	Takifugu rubripes	85.50	0.00e+00	887.00
IUUC-Tsy-119167	Tarsius syrichta	86.20	0.00e+00	1063.00
IUUC-Tni-120788	Tetraodon nigroviridis	62.79	0.00e+00	991.00
IUUC-Tbe-127830	Tupaia belangeri	92.40	0.00e+00	1145.00
IUUC-Ttr-128631	Tursiops truncatus	92.27	0.00e+00	1613.00
IUUC-Vpa-130713	Vicugna pacos	92.35	0.00e+00	1390.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence