iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012504

UUCD1 version

UUC-BoT-01002

Ensembl Protein ID

ENSBTAP00000002200.3

UniProt Accession

Q9N0T1; A5D9D9; Q2KJA8; STC1_BOVIN

Genbank Protein ID

AAF68996.1; ABQ12998.1; AAI05436.1

Protein Name

Stanniocalcin-1

Genbank Nucleotide ID

AF257506; BT030558; BC105435

Gene Name

STC1; STC

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000001687.3	ENSBTAT00000002200.3	ENSBTAP00000002200.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	95.14	9.00e-138	486.00	IUUC-Hsa-046890

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Bos taurus

Functional Description
(View)

Stimulates renal phosphate reabsorption, and could therefore prevent hypercalcemia.

Protein Sequence
(Fasta)

MLQNSAVLLV LVISASATHE AEQNDSVSLR KSRVAAQNSA EVIRCLNSAL QVGCGAFACL 60
ENSTCDTDGM YDICKSFLYS AAKFDTQGKA FVKESLKCIA NGVTSKVFLA IRRCSTFQRM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTTTGCAAA AGCCAGAGGT GCAAGGAGCA GCGACTGCAG CAGCAACAAC AGCAGCAGCA 60
AAAAGCGCCA GCGGAAGCAA CATCAGCAGC AGCAACAACA GAAAAATCCT CATCAAATCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0325--Glycoprotein
KW-0372--Hormone
KW-1185--Reference proteome
KW-0964--Secreted
KW-0732--Signal

Interpro

IPR004978--Stanniocalcin

Pfam

PF03298--Stanniocalcin

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005615--C:extracellular space
GO:0005634--C:nucleus
GO:0006874--P:cellular calcium ion homeostasis
GO:0035988--P:chondrocyte proliferation
GO:0001886--P:endothelial cell morphogenesis
GO:0003421--P:growth plate cartilage axis specification
GO:0051926--P:negative regulation of calcium ion transport
GO:0010596--P:negative regulation of endothelial cell migration
GO:1903403--P:negative regulation of renal phosphate excretion
GO:0090280--P:positive regulation of calcium ion import
GO:0044070--P:regulation of anion transport
GO:0086004--P:regulation of cardiac muscle cell contraction

KEGG

bta:338078

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001570	Ailuropoda melanoleuca	95.95	2.00e-140	490.00
IUUC-Apl-003856	Anas platyrhynchos	85.59	5.00e-122	429.00
IUUC-Aca-004398	Anolis carolinensis	67.23	2.00e-71	261.00
IUUC-Ame-011748	Astyanax mexicanus	69.35	2.00e-76	278.00
IUUC-Cja-019777	Callithrix jacchus	89.47	1.00e-124	438.00
IUUC-Cfa-020480	Canis familiaris	95.55	6.00e-140	489.00
IUUC-Cpo-021687	Cavia porcellus	86.18	5.00e-129	452.00
IUUC-Csa-023893	Chlorocebus sabaeus	94.74	1.00e-138	484.00
IUUC-Cho-024292	Choloepus hoffmanni	89.66	8.00e-89	318.00
IUUC-Cin-025656	Ciona intestinalis	27.46	2.00e-22	99.00
IUUC-Dre-027654	Danio rerio	64.85	3.00e-80	291.00
IUUC-Dno-029650	Dasypus novemcinctus	89.88	1.00e-125	442.00
IUUC-Dor-030359	Dipodomys ordii	90.82	2.00e-114	404.00
IUUC-Ete-032471	Echinops telfairi	86.81	2.00e-44	172.00
IUUC-Eca-034200	Equus caballus	94.74	7.00e-139	486.00
IUUC-Eeu-034496	Erinaceus europaeus	95.14	8.00e-140	489.00
IUUC-Fca-036162	Felis catus	96.36	7.00e-141	492.00
IUUC-Fal-037021	Ficedula albicollis	83.41	5.00e-116	410.00
IUUC-Gmo-039330	Gadus morhua	62.38	1.00e-77	282.00
IUUC-Gga-040171	Gallus gallus	85.59	1.00e-121	428.00
IUUC-Gac-041717	Gasterosteus aculeatus	65.67	5.00e-80	290.00
IUUC-Gma-044347	Glycine max	35.42	2.00e-01	30.00
IUUC-Ggo-045186	Gorilla gorilla	95.14	4.00e-139	486.00
IUUC-Hsa-046890	Homo sapiens	95.14	4.00e-139	486.00
IUUC-Hvu-047382	Hordeum vulgare	34.43	1.40e-02	33.50
IUUC-Itr-048117	Ictidomys tridecemlineatus	93.93	1.00e-129	455.00
IUUC-Lch-050223	Latimeria chalumnae	76.11	1.00e-113	402.00
IUUC-Loc-052942	Lepisosteus oculatus	69.74	1.00e-75	276.00
IUUC-Laf-053378	Loxodonta africana	93.93	9.00e-138	482.00
IUUC-Mcc-054663	Macaca mulatta	95.55	4.00e-140	490.00
IUUC-Meu-056475	Macropus eugenii	76.71	1.00e-114	405.00
IUUC-Mga-059322	Meleagris gallopavo	85.24	2.00e-109	387.00
IUUC-Mmr-061237	Microcebus murinus	94.74	2.00e-131	461.00
IUUC-Mdo-062684	Monodelphis domestica	83.74	3.00e-124	437.00
IUUC-Mmu-064414	Mus musculus	92.71	2.00e-130	457.00
IUUC-Mpu-065881	Mustela putorius furo	95.14	3.00e-139	487.00
IUUC-Mlu-067435	Myotis lucifugus	94.33	2.00e-138	484.00
IUUC-Nle-069359	Nomascus leucogenys	94.74	1.00e-138	484.00
IUUC-Opr-070546	Ochotona princeps	86.64	2.00e-127	447.00
IUUC-Ont-072479	Oreochromis niloticus	66.84	5.00e-79	287.00
IUUC-Oan-072835	Ornithorhynchus anatinus	85.43	6.00e-129	452.00
IUUC-Ocu-074860	Oryctolagus cuniculus	82.59	9.00e-123	432.00
IUUC-Olo-080649	Oryza longistaminata	25.26	3.40e-02	32.30
IUUC-Ola-086759	Oryzias latipes	66.83	6.00e-83	300.00
IUUC-Oga-089120	Otolemur garnettii	93.50	4.00e-129	453.00
IUUC-Oar-089489	Ovis aries	98.79	4.00e-145	507.00
IUUC-Ptr-091170	Pan troglodytes	95.14	4.00e-139	486.00
IUUC-Pan-092640	Papio anubis	95.55	7.00e-140	489.00
IUUC-Psi-093161	Pelodiscus sinensis	86.23	1.00e-122	431.00
IUUC-Pfo-096888	Poecilia formosa	64.39	2.00e-79	288.00
IUUC-Pab-098660	Pongo abelii	95.14	4.00e-139	486.00
IUUC-Pop-099280	Populus trichocarpa	23.66	4.60e-02	32.00
IUUC-Pca-100490	Procavia capensis	92.50	2.00e-86	310.00
IUUC-Pva-102842	Pteropus vampyrus	94.74	2.00e-139	487.00
IUUC-Rno-105078	Rattus norvegicus	92.31	5.00e-130	456.00
IUUC-Sha-106600	Sarcophilus harrisii	84.21	3.00e-108	384.00
IUUC-Sly-111589	Solanum lycopersicum	28.41	5.50e-02	31.60
IUUC-Sar-113441	Sorex araneus	92.31	2.00e-133	468.00
IUUC-Ssc-115748	Sus scrofa	95.14	8.00e-141	492.00
IUUC-Tgu-117137	Taeniopygia guttata	83.41	8.00e-115	405.00
IUUC-Tru-118332	Takifugu rubripes	64.02	2.00e-76	278.00
IUUC-Tsy-118890	Tarsius syrichta	93.52	2.00e-136	478.00
IUUC-Tni-120180	Tetraodon nigroviridis	47.14	4.00e-55	207.00
IUUC-Tae-123845	Triticum aestivum	36.07	4.00e-03	35.40
IUUC-Tbe-127571	Tupaia belangeri	77.95	8.00e-58	216.00
IUUC-Ttr-128753	Tursiops truncatus	96.36	7.00e-141	492.00
IUUC-Vpa-130634	Vicugna pacos	96.14	2.00e-117	414.00
IUUC-Xtr-131971	Xenopus tropicalis	72.56	8.00e-97	346.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence