iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000003144.6	ENSGALT00000049075.2	ENSGALP00000053240.1
ENSGALG00000003144.6	ENSGALT00000004971.5	ENSGALP00000004962.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.10e-08	35.8	22	63

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCl+ f+  p+++pCgH f+a Cl q w     s+ + f+CP Cr
   Q: 22   CSICLSIFDA-PVTVPCGHNFCAYCLeQTW----ASQVRDFSCPQCR 63
           ********99.*******************....99**********8 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MATLTKAQSE PNLLALEEDL TCSICLSIFD APVTVPCGHN FCAYCLEQTW ASQVRDFSCP 60
QCRTTFPDRP QLHKNTVLCR VVEQLQGCGD GKEDDEHEEE EQEAAAPIYC DSCLQAAATQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGCCGGAC GGCAGCAGCG GGAGAATGGC GACGTTGACC AAAGCTCAGT CGGAGCCGAA 60
TCTGTTGGCG CTGGAGGAGG ACCTGACGTG CTCCATCTGC CTCAGCATCT TCGACGCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0003723--F:RNA binding
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0006513--P:protein monoubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen

KEGG

gga:417401

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002424	Ailuropoda melanoleuca	48.25	7.00e-174	603.00
IUUC-Apl-004101	Anas platyrhynchos	71.88	0.00e+00	849.00
IUUC-Aca-005025	Anolis carolinensis	53.53	0.00e+00	694.00
IUUC-Ame-010917	Astyanax mexicanus	33.33	5.00e-40	158.00
IUUC-Bta-012735	Bos taurus	50.95	3.00e-179	621.00
IUUC-Cja-019996	Callithrix jacchus	44.32	7.00e-88	317.00
IUUC-Cfa-020466	Canis familiaris	47.48	5.00e-175	607.00
IUUC-Cpo-021737	Cavia porcellus	45.65	3.00e-167	581.00
IUUC-Csa-023217	Chlorocebus sabaeus	47.66	5.00e-173	600.00
IUUC-Cho-024346	Choloepus hoffmanni	37.20	2.00e-44	172.00
IUUC-Dre-028527	Danio rerio	25.23	5.00e-38	152.00
IUUC-Dno-030082	Dasypus novemcinctus	51.04	0.00e+00	637.00
IUUC-Dor-030335	Dipodomys ordii	34.52	9.00e-71	261.00
IUUC-Ete-032923	Echinops telfairi	46.88	1.00e-152	532.00
IUUC-Eca-033411	Equus caballus	47.89	5.00e-174	603.00
IUUC-Eeu-034656	Erinaceus europaeus	45.71	3.00e-89	322.00
IUUC-Fca-035371	Felis catus	47.53	2.00e-172	598.00
IUUC-Fal-037008	Ficedula albicollis	66.77	0.00e+00	808.00
IUUC-Gmo-038668	Gadus morhua	36.17	2.00e-106	379.00
IUUC-Gac-041409	Gasterosteus aculeatus	37.46	2.00e-118	419.00
IUUC-Ggo-044518	Gorilla gorilla	46.15	4.00e-89	322.00
IUUC-Hsa-045828	Homo sapiens	46.88	3.00e-169	588.00
IUUC-Itr-049070	Ictidomys tridecemlineatus	40.29	8.00e-129	453.00
IUUC-Lch-050478	Latimeria chalumnae	38.59	5.00e-130	457.00
IUUC-Loc-052864	Lepisosteus oculatus	38.58	8.00e-120	424.00
IUUC-Laf-054325	Loxodonta africana	47.08	1.00e-95	342.00
IUUC-Mcc-054920	Macaca mulatta	47.20	2.00e-172	598.00
IUUC-Meu-056367	Macropus eugenii	64.33	1.00e-64	241.00
IUUC-Mga-059975	Meleagris gallopavo	79.05	0.00e+00	947.00
IUUC-Mmr-060748	Microcebus murinus	47.69	3.00e-173	601.00
IUUC-Mdo-062904	Monodelphis domestica	48.51	2.00e-161	562.00
IUUC-Mmu-063891	Mus musculus	46.56	5.00e-170	590.00
IUUC-Mpu-066473	Mustela putorius furo	48.06	3.00e-178	618.00
IUUC-Mlu-068185	Myotis lucifugus	48.33	9.00e-174	603.00
IUUC-Nle-070177	Nomascus leucogenys	47.28	2.00e-170	592.00
IUUC-Opr-070558	Ochotona princeps	42.86	2.00e-87	315.00
IUUC-Ont-071368	Oreochromis niloticus	35.85	8.00e-110	390.00
IUUC-Oan-072819	Ornithorhynchus anatinus	32.95	4.00e-22	98.20
IUUC-Ocu-074461	Oryctolagus cuniculus	47.97	5.00e-93	335.00
IUUC-Ogu-078203	Oryza glumaepatula	38.67	1.00e-08	54.30
IUUC-Ola-087180	Oryzias latipes	26.85	1.00e-53	204.00
IUUC-Oga-088937	Otolemur garnettii	46.74	5.00e-163	567.00
IUUC-Oar-089781	Ovis aries	48.17	2.00e-118	418.00
IUUC-Ptr-090771	Pan troglodytes	46.15	4.00e-89	322.00
IUUC-Pan-092830	Papio anubis	47.04	3.00e-172	598.00
IUUC-Psi-093664	Pelodiscus sinensis	60.66	0.00e+00	728.00
IUUC-Pma-094147	Petromyzon marinus	26.55	2.00e-50	193.00
IUUC-Pfo-096528	Poecilia formosa	36.13	6.00e-118	417.00
IUUC-Pab-097588	Pongo abelii	47.04	1.00e-168	586.00
IUUC-Pca-100890	Procavia capensis	47.89	3.00e-90	325.00
IUUC-Pva-102314	Pteropus vampyrus	49.13	7.00e-169	587.00
IUUC-Rno-105234	Rattus norvegicus	45.43	4.00e-88	318.00
IUUC-Sce-106362	Saccharomyces cerevisiae	41.79	7.00e-09	54.70
IUUC-Sha-106807	Sarcophilus harrisii	46.34	5.00e-161	560.00
IUUC-Sar-113283	Sorex araneus	43.84	8.00e-74	270.00
IUUC-Ssc-115878	Sus scrofa	50.44	6.00e-61	226.00
IUUC-Tgu-117026	Taeniopygia guttata	62.28	0.00e+00	639.00
IUUC-Tru-117794	Takifugu rubripes	36.32	5.00e-105	374.00
IUUC-Tsy-119001	Tarsius syrichta	32.37	8.00e-20	91.70
IUUC-Tni-120550	Tetraodon nigroviridis	26.55	1.00e-62	234.00
IUUC-Tbe-127580	Tupaia belangeri	41.03	1.00e-71	263.00
IUUC-Ttr-128648	Tursiops truncatus	64.89	1.00e-80	293.00
IUUC-Vpa-130254	Vicugna pacos	68.60	2.00e-76	279.00
IUUC-Xtr-132892	Xenopus tropicalis	44.38	8.00e-83	300.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence