iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-060139

Ensembl Protein ID

ENSMGAP00000001588.2

UniProt Accession

G1MT77; G1MT77_MELGA

Protein Name

Histone-lysine N-methyltransferase

Gene Name

WHSC1L1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000002028.2	ENSMGAT00000002251.2	ENSMGAP00000001588.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.70e-09	37.5	702	747

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek.CrewfHpaClklsveeelpnsekwiCpkCrs 53
           +vC +C+++ge   slv Ce  C++ fH +Cl+l+    +p+++ ++C++C++
   Q: 702  TVCQICESSGE---SLVSCEGeCCSTFHMECLGLK---AMPEEK-FFCTECKN 747
           79*********...5********************...999997.******86 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MDFSFSFMQG IMGNTIQQPP QLIDSANIRQ EDAFDASSDI AEDGGQTPYE AALQQGFQYP 60
TPTAEDLPPI ANGYPATINV YEPQAKFQTY SQYPNGSANG FGTVRNFSPP EYYHVENSNA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATTTCT CTTTCTCTTT CATGCAAGGG ATCATGGGAA ACACAATTCA GCAACCACCT 60
CAGCTCATTG ACTCAGCCAA CATCCGCCAG GAGGATGCCT TTGATGCCAG CAGTGACATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR006560--AWS_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51215--AWS
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00855--PWWP
PF00856--SET

SMART

SM00570--AWS
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000310	Aegilops tauschii	28.43	6.00e-12	65.90
IUUC-Aml-001809	Ailuropoda melanoleuca	86.31	0.00e+00	1584.00
IUUC-Apl-004027	Anas platyrhynchos	87.11	0.00e+00	2331.00
IUUC-Aca-005380	Anolis carolinensis	86.20	0.00e+00	2284.00
IUUC-Ame-011234	Astyanax mexicanus	60.09	0.00e+00	1444.00
IUUC-Bta-013575	Bos taurus	83.39	0.00e+00	2324.00
IUUC-Cja-020013	Callithrix jacchus	85.45	0.00e+00	2454.00
IUUC-Cfa-021060	Canis familiaris	84.42	0.00e+00	2345.00
IUUC-Cpo-021834	Cavia porcellus	84.48	0.00e+00	2329.00
IUUC-Csa-023370	Chlorocebus sabaeus	85.52	0.00e+00	2449.00
IUUC-Cho-025058	Choloepus hoffmanni	80.76	0.00e+00	633.00
IUUC-Dre-027664	Danio rerio	67.95	0.00e+00	1258.00
IUUC-Dno-029302	Dasypus novemcinctus	83.87	0.00e+00	2316.00
IUUC-Eca-033626	Equus caballus	82.70	0.00e+00	2316.00
IUUC-Fca-035556	Felis catus	85.17	0.00e+00	2380.00
IUUC-Fal-037101	Ficedula albicollis	90.27	0.00e+00	2422.00
IUUC-Gmo-038901	Gadus morhua	57.83	0.00e+00	1556.00
IUUC-Gga-040366	Gallus gallus	95.91	0.00e+00	2523.00
IUUC-Gac-042047	Gasterosteus aculeatus	62.85	0.00e+00	1363.00
IUUC-Ggo-044695	Gorilla gorilla	82.91	0.00e+00	2336.00
IUUC-Hsa-046080	Homo sapiens	85.78	0.00e+00	2453.00
IUUC-Itr-048622	Ictidomys tridecemlineatus	84.55	0.00e+00	2389.00
IUUC-Lch-050544	Latimeria chalumnae	71.66	0.00e+00	1645.00
IUUC-Loc-052656	Lepisosteus oculatus	66.25	0.00e+00	1624.00
IUUC-Laf-054112	Loxodonta africana	84.23	0.00e+00	2352.00
IUUC-Mcc-054956	Macaca mulatta	85.38	0.00e+00	2457.00
IUUC-Meu-056051	Macropus eugenii	82.87	0.00e+00	2093.00
IUUC-Mmr-060789	Microcebus murinus	84.07	0.00e+00	2408.00
IUUC-Mdo-062908	Monodelphis domestica	87.72	0.00e+00	2390.00
IUUC-Mmu-063165	Mus musculus	78.88	0.00e+00	2163.00
IUUC-Mpu-066002	Mustela putorius furo	85.03	0.00e+00	2375.00
IUUC-Nle-069417	Nomascus leucogenys	85.06	0.00e+00	2288.00
IUUC-Ont-071900	Oreochromis niloticus	59.24	0.00e+00	1599.00
IUUC-Oan-072857	Ornithorhynchus anatinus	88.12	0.00e+00	2412.00
IUUC-Ocu-073809	Oryctolagus cuniculus	84.83	0.00e+00	2359.00
IUUC-Obr-076178	Oryza brachyantha	28.57	2.00e-10	60.80
IUUC-Ola-087085	Oryzias latipes	58.86	0.00e+00	1578.00
IUUC-Oga-088289	Otolemur garnettii	83.66	0.00e+00	2348.00
IUUC-Oar-089398	Ovis aries	83.94	0.00e+00	2329.00
IUUC-Ptr-090510	Pan troglodytes	85.65	0.00e+00	2449.00
IUUC-Pan-092291	Papio anubis	85.66	0.00e+00	2452.00
IUUC-Psi-093547	Pelodiscus sinensis	92.40	0.00e+00	2501.00
IUUC-Pma-094747	Petromyzon marinus	57.61	0.00e+00	943.00
IUUC-Pfo-096669	Poecilia formosa	58.84	0.00e+00	1600.00
IUUC-Pab-097727	Pongo abelii	85.52	0.00e+00	2428.00
IUUC-Pca-100474	Procavia capensis	77.59	0.00e+00	2056.00
IUUC-Pva-102539	Pteropus vampyrus	83.76	0.00e+00	2099.00
IUUC-Rno-105685	Rattus norvegicus	81.65	0.00e+00	2190.00
IUUC-Sha-107287	Sarcophilus harrisii	87.87	0.00e+00	2371.00
IUUC-Sar-113547	Sorex araneus	80.34	0.00e+00	2239.00
IUUC-Ssc-116208	Sus scrofa	85.24	0.00e+00	2434.00
IUUC-Tgu-117006	Taeniopygia guttata	92.80	0.00e+00	2506.00
IUUC-Tru-118375	Takifugu rubripes	62.29	0.00e+00	1456.00
IUUC-Tsy-119323	Tarsius syrichta	84.41	0.00e+00	2364.00
IUUC-Tni-120509	Tetraodon nigroviridis	58.94	0.00e+00	1628.00
IUUC-Tca-121456	Theobroma cacao	30.81	2.00e-19	90.50
IUUC-Tae-124687	Triticum aestivum	28.43	6.00e-12	65.90
IUUC-Ttr-128240	Tursiops truncatus	82.28	0.00e+00	2266.00
IUUC-Vpa-130666	Vicugna pacos	84.07	0.00e+00	2311.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence