iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aly-005473

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Eukaryotic translation initiation factor 3 subunit I

Genbank Nucleotide ID

GL348716

Gene Name

TRIP-1; ARALYDRAFT_904081

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
scaffold_403582.1	scaffold_403582.1	scaffold_403582.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.60e-27	93.9	50	87
UBD/Beta-Prp	3.20e-54	184.8	6	233

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH++ v+c++   d  +l++Gs D t k+WD+++g+ l
   Q: 50   GHNGAVWCCDVsRDsSRLITGSADQTAKLWDVKSGKEL 87
           8***********77799****************99875 PP

UBD/Beta-Prp

   S: 48   lsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee........ 131
           ++ghe + t +++++dg++l ++++D+t  +w  ++g+ + t++gh+  v+++++s+++++l++Gs+d+t+++wd+++g++l +        
   Q: 6    MKGHERPLTFLRYNKDGDLLFSCAKDHTPTLWFADNGERLGTYRGHNGAVWCCDVSRDSSRLITGSADQTAKLWDVKSGKELFTfkfgsptr 97
           489*******************************************************************************99******** PP
   S: 132  ..............................................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.. 175
                                                         + +g++  +n +v+ p ++ +vs++ D+++r+Wd +tgkll +   
   Q: 98   svdfalgdhlavittdhfvdrmaaihvkriaedpedqvsdsvlvlqCPDGKK-RINRAVWGPLNQTIVSAGEDTVIRIWDTETGKLLNETne 188
           *******************************************987777766.6788899999************************99989 PP
   S: 176  tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng 220
           + gh+++++sl    +  ++++gs+d+t klwd++t + ++t++ 
   Q: 189  EVGHKKAITSLCKAADDSHFLTGSHDKTAKLWDMRTLTLIKTYTT 233
           667***********************************9999985 PP

Organism

Arabidopsis lyrata

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MRPILMKGHE RPLTFLRYNK DGDLLFSCAK DHTPTLWFAD NGERLGTYRG HNGAVWCCDV 60
SRDSSRLITG SADQTAKLWD VKSGKELFTF KFGSPTRSVD FALGDHLAVI TTDHFVDRMA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAACCCTAG GAAATTGAAG ATGAGGCCGA TTTTGATGAA GGGACATGAA CGTCCATTGA 60
CGTTCCTGAG GTACAACAAA GATGGCGATC TACTTTTCTC CTGCGCCAAG GATCACACTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR027525--eIF3i
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0006446--P:regulation of translational initiation
GO:0046686--P:response to cadmium ion
GO:0009651--P:response to salt stress

KEGG

aly:ARALYDRAFT_904081

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000115	Aegilops tauschii	42.07	6.00e-54	204.00
IUUC-Aml-001321	Ailuropoda melanoleuca	44.51	2.00e-82	298.00
IUUC-Atr-002468	Amborella trichopoda	73.53	2.00e-87	314.00
IUUC-Apl-003841	Anas platyrhynchos	44.82	2.00e-84	304.00
IUUC-Aca-005123	Anolis carolinensis	44.51	5.00e-85	306.00
IUUC-Ago-008000	Ashbya gossypii	41.27	3.00e-73	268.00
IUUC-Acl-008098	Aspergillus clavatus	42.64	2.00e-74	271.00
IUUC-Afl-008494	Aspergillus flavus	43.77	9.00e-78	282.00
IUUC-Afu-009080	Aspergillus fumigatus	42.34	2.00e-73	268.00
IUUC-Ani-009230	Aspergillus nidulans	43.77	2.00e-76	278.00
IUUC-Aor-010114	Aspergillus oryzae	43.77	9.00e-78	282.00
IUUC-Ate-010285	Aspergillus terreus	42.86	2.00e-76	278.00
IUUC-Bgr-012121	Blumeria graminis	41.72	4.00e-71	260.00
IUUC-Bta-013143	Bos taurus	44.82	5.00e-83	300.00
IUUC-Bdi-015019	Brachypodium distachyon	77.74	3.00e-152	530.00
IUUC-Bol-015709	Brassica oleracea	86.36	1.00e-174	605.00
IUUC-Bra-017760	Brassica rapa	86.36	4.00e-176	610.00
IUUC-Cel-018226	Caenorhabditis elegans	37.96	6.00e-67	246.00
IUUC-Cja-019741	Callithrix jacchus	45.12	2.00e-83	301.00
IUUC-Cfa-021204	Canis familiaris	44.82	1.00e-82	298.00
IUUC-Cpo-021661	Cavia porcellus	44.21	3.00e-82	297.00
IUUC-Cre-022952	Chlamydomonas reinhardtii	51.52	1.00e-101	362.00
IUUC-Csa-024038	Chlorocebus sabaeus	45.12	2.00e-83	301.00
IUUC-Cgl-026583	Colletotrichum gloeosporioides	44.82	2.00e-77	281.00
IUUC-Cne-026838	Cryptococcus neoformans	40.79	3.00e-76	278.00
IUUC-Cme-027304	Cyanidioschyzon merolae	51.38	6.00e-85	306.00
IUUC-Dno-029171	Dasypus novemcinctus	44.65	8.00e-82	296.00
IUUC-Dse-031191	Dothistroma septosporum	46.39	6.00e-81	293.00
IUUC-Eca-033259	Equus caballus	44.82	2.00e-82	298.00
IUUC-Eeu-035153	Erinaceus europaeus	40.00	2.00e-23	102.00
IUUC-Fca-036489	Felis catus	44.82	2.00e-82	298.00
IUUC-Fal-037485	Ficedula albicollis	44.51	4.00e-84	303.00
IUUC-Fox-037860	Fusarium oxysporum	44.82	4.00e-77	280.00
IUUC-Fso-038188	Fusarium solani	43.60	2.00e-74	272.00
IUUC-Ggr-040045	Gaeumannomyces graminis	42.33	7.00e-75	273.00
IUUC-Gga-040645	Gallus gallus	44.35	5.00e-83	300.00
IUUC-Gma-043246	Glycine max	82.32	3.00e-164	570.00
IUUC-Ggo-045578	Gorilla gorilla	45.12	2.00e-83	301.00
IUUC-Hsa-046734	Homo sapiens	45.12	2.00e-83	301.00
IUUC-Hvu-047553	Hordeum vulgare	77.13	5.00e-152	529.00
IUUC-Itr-048467	Ictidomys tridecemlineatus	44.82	2.00e-82	298.00
IUUC-Lch-049620	Latimeria chalumnae	44.88	3.00e-76	277.00
IUUC-Lpe-051338	Leersia perrieri	76.04	2.00e-142	497.00
IUUC-Lma-053047	Leptosphaeria maculans	47.40	3.00e-84	304.00
IUUC-Laf-053801	Loxodonta africana	44.55	9.00e-80	289.00
IUUC-Mcc-055498	Macaca mulatta	40.55	3.00e-65	241.00
IUUC-Meu-056729	Macropus eugenii	40.85	4.00e-74	270.00
IUUC-Mor-057025	Magnaporthe oryzae	42.99	2.00e-74	272.00
IUUC-Mpo-057511	Magnaporthe poae	44.21	2.00e-76	278.00
IUUC-Mtr-058051	Medicago truncatula	81.10	4.00e-163	566.00
IUUC-Mga-059229	Meleagris gallopavo	44.24	8.00e-82	296.00
IUUC-Mmr-060764	Microcebus murinus	44.82	2.00e-83	301.00
IUUC-Mdo-062088	Monodelphis domestica	43.60	1.00e-82	299.00
IUUC-Mmu-064304	Mus musculus	44.51	4.00e-83	300.00
IUUC-Mac-065520	Musa acuminata	75.54	7.00e-150	522.00
IUUC-Mpu-066340	Mustela putorius furo	44.82	2.00e-82	298.00
IUUC-Mlu-067111	Myotis lucifugus	44.51	2.00e-82	298.00
IUUC-Nfi-068478	Neosartorya fischeri	42.04	4.00e-74	270.00
IUUC-Ncr-068820	Neurospora crassa	44.82	2.00e-76	278.00
IUUC-Nle-069903	Nomascus leucogenys	44.82	8.00e-83	299.00
IUUC-Opr-070221	Ochotona princeps	43.60	2.00e-80	291.00
IUUC-Oan-073660	Ornithorhynchus anatinus	43.69	1.00e-70	258.00
IUUC-Ocu-074039	Oryctolagus cuniculus	44.82	1.00e-82	298.00
IUUC-Oba-075395	Oryza barthii	71.65	2.00e-137	480.00
IUUC-Obr-076334	Oryza brachyantha	74.39	5.00e-144	502.00
IUUC-Ogl-077751	Oryza glaberrima	78.35	7.00e-155	538.00
IUUC-Ogu-078207	Oryza glumaepatula	77.37	1.00e-151	528.00
IUUC-Oin-079878	Oryza indica	78.05	2.00e-153	534.00
IUUC-Olo-080677	Oryza longistaminata	67.02	4.00e-145	506.00
IUUC-Ome-081228	Oryza meridionalis	59.92	2.00e-78	284.00
IUUC-Oni-082411	Oryza nivara	68.90	2.00e-129	454.00
IUUC-Opu-083136	Oryza punctata	78.66	3.00e-155	540.00
IUUC-Oru-084916	Oryza rufipogon	75.96	2.00e-151	527.00
IUUC-Osa-085776	Oryza sativa	78.35	7.00e-155	538.00
IUUC-Olu-087602	Ostreococcus lucimarinus	58.72	6.00e-113	399.00
IUUC-Oga-088154	Otolemur garnettii	45.12	3.00e-83	301.00
IUUC-Oar-089915	Ovis aries	44.51	3.00e-82	297.00
IUUC-Ptr-091124	Pan troglodytes	36.50	3.00e-55	207.00
IUUC-Pan-092035	Papio anubis	45.12	2.00e-83	301.00
IUUC-Psi-094096	Pelodiscus sinensis	46.23	2.00e-49	187.00
IUUC-Pno-094988	Phaeosphaeria nodorum	43.73	4.00e-72	264.00
IUUC-Ppa-095949	Physcomitrella patens	69.82	2.00e-142	498.00
IUUC-Pab-097726	Pongo abelii	45.12	2.00e-83	301.00
IUUC-Pop-099617	Populus trichocarpa	79.88	9.00e-159	551.00
IUUC-Pca-101014	Procavia capensis	44.82	2.00e-83	301.00
IUUC-Ppe-101320	Prunus persica	82.93	2.00e-165	574.00
IUUC-Pva-102789	Pteropus vampyrus	42.38	1.00e-72	265.00
IUUC-Pte-104278	Pyrenophora teres	45.87	5.00e-80	290.00
IUUC-Pyt-104492	Pyrenophora triticirepentis	45.87	5.00e-80	290.00
IUUC-Rno-105867	Rattus norvegicus	42.07	1.00e-67	249.00
IUUC-Sce-106251	Saccharomyces cerevisiae	39.46	6.00e-70	256.00
IUUC-Sha-107039	Sarcophilus harrisii	43.60	8.00e-83	299.00
IUUC-Ssl-108478	Sclerotinia sclerotiorum	45.26	1.00e-79	288.00
IUUC-Smo-108728	Selaginella moellendorffii	71.25	9.00e-142	495.00
IUUC-Sit-110801	Setaria italica	77.13	1.00e-151	528.00
IUUC-Sly-111326	Solanum lycopersicum	81.10	5.00e-162	562.00
IUUC-Stu-112458	Solanum tuberosum	82.93	2.00e-164	571.00
IUUC-Sbi-114063	Sorghum bicolor	76.22	2.00e-150	523.00
IUUC-Ssc-116080	Sus scrofa	44.82	5.00e-83	300.00
IUUC-Tgu-116988	Taeniopygia guttata	44.65	6.00e-84	303.00
IUUC-Tca-121316	Theobroma cacao	82.32	1.00e-162	565.00
IUUC-Tre-122097	Trichoderma reesei	44.21	7.00e-76	276.00
IUUC-Tvi-122442	Trichoderma virens	43.90	1.00e-75	275.00
IUUC-Tae-125800	Triticum aestivum	77.13	7.00e-152	529.00
IUUC-Tur-126334	Triticum urartu	67.68	2.00e-126	444.00
IUUC-Tme-127038	Tuber melanosporum	45.29	5.00e-82	296.00
IUUC-Vda-129841	Verticillium dahliae	46.34	5.00e-78	283.00
IUUC-Vvi-131076	Vitis vinifera	80.18	1.00e-160	558.00
IUUC-Xtr-132395	Xenopus tropicalis	45.73	3.00e-86	311.00
IUUC-Zma-135667	Zea mays	75.91	1.00e-150	525.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence