iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ppe-101320

Ensembl Protein ID

EMJ23865

UniProt Accession

M5XXB6; M5XXB6_PRUPE

Genbank Protein ID

EMJ23865.1

Protein Name

Eukaryotic translation initiation factor 3 subunit I

Genbank Nucleotide ID

KB638913

Gene Name

PRUPE_ppa008567mg

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PRUPE_ppa008567mg	EMJ23865	EMJ23865

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-24	85.5	50	87
UBD/Beta-Prp	1.40e-41	143.1	7	251

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH++ v+c++   d  +l++Gs D t k+W++ tg +l
   Q: 50   GHNGAVWCCDVsRDsARLITGSADQTAKLWNVQTGQQL 87
           8**********977799*****************9876 PP

UBD/Beta-Prp

   S: 49   sgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.................. 131
           +ghe + t +k+++dg++l ++++D++  vw  ++g+ + t++gh+  v+++++s+++ +l++Gs+d+t+++w+++tgq l +                  
   Q: 7    KGHERPLTFLKYNRDGDLLFSCAKDHNPTVWFADNGERLGTYRGHNGAVWCCDVSRDSARLITGSADQTAKLWNVQTGQQLFTfnfdsparavdlsvgdrl 107
           78888888888888888888888888888888888888888888888888888888888888888888888888888888888888888888888888888 PP
   S: 132  .................................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tgghtdsvyslsfdsngkelvs 197
                                            +l+g +g +n +v+ p ++ ++s++ D ++r+Wd++tgkll++   + gh++ ++sl+ + +g ++++
   Q: 108  avittdpfmelssaihvkriandpadqvgesalILKGPQGRINRAVWGPLNRTIISAGEDAVIRIWDSETGKLLKENdkEVGHKKTITSLAKSVDGSHFLT 208
           88888888888888888888889******************************************************99667******************* PP
   S: 198  gsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgs 241
           gsld++ klwd++t + ++t+    ++v+ v++sp  +++v g+
   Q: 209  GSLDKSAKLWDIRTLTLIKTYVTE-RPVNAVAMSPLLDHVVLGG 251
           ********************9875.4666666665555554444 PP

Organism

Prunus persica

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MRPILMKGHE RPLTFLKYNR DGDLLFSCAK DHNPTVWFAD NGERLGTYRG HNGAVWCCDV 60
SRDSARLITG SADQTAKLWN VQTGQQLFTF NFDSPARAVD LSVGDRLAVI TTDPFMELSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATATCTGCCA AAACTCTACC TCTGCATCTG CCTCCGTTGG GTGTCGCCAC AGCAGTTCTA 60
CACTAGCAAT CTCGTCGATT CGTTGTTGCT CCGACTCCGA ACATGAGGCC TATTCTGATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR027525--eIF3i
IPR020472--G-protein_beta_WD-40_rep
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0006446--P:regulation of translational initiation

KEGG

pper:PRUPE_ppa008567mg

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000115	Aegilops tauschii	45.16	1.00e-57	216.00
IUUC-Aml-001321	Ailuropoda melanoleuca	47.71	4.00e-84	303.00
IUUC-Atr-002468	Amborella trichopoda	72.50	7.00e-100	355.00
IUUC-Apl-003841	Anas platyrhynchos	47.08	7.00e-86	309.00
IUUC-Aca-005123	Anolis carolinensis	46.63	2.00e-86	311.00
IUUC-Aly-005473	Arabidopsis lyrata	82.93	1.00e-165	574.00
IUUC-Ath-007094	Arabidopsis thaliana	82.62	1.00e-165	574.00
IUUC-Ago-008000	Ashbya gossypii	44.61	7.00e-76	276.00
IUUC-Acl-008098	Aspergillus clavatus	44.85	5.00e-77	280.00
IUUC-Afl-008494	Aspergillus flavus	45.85	1.00e-80	291.00
IUUC-Afu-009080	Aspergillus fumigatus	45.02	7.00e-77	279.00
IUUC-Ani-009230	Aspergillus nidulans	46.32	1.00e-79	288.00
IUUC-Aor-010114	Aspergillus oryzae	45.85	1.00e-80	291.00
IUUC-Ate-010285	Aspergillus terreus	45.40	5.00e-79	286.00
IUUC-Ame-011534	Astyanax mexicanus	46.50	3.00e-87	314.00
IUUC-Bgr-012121	Blumeria graminis	41.54	2.00e-72	265.00
IUUC-Bta-013143	Bos taurus	46.93	1.00e-84	305.00
IUUC-Bci-013950	Botrytis cinerea	44.65	3.00e-79	287.00
IUUC-Bdi-015019	Brachypodium distachyon	80.98	2.00e-159	553.00
IUUC-Bol-015709	Brassica oleracea	83.64	6.00e-169	586.00
IUUC-Bra-017760	Brassica rapa	83.64	3.00e-170	591.00
IUUC-Cel-018226	Caenorhabditis elegans	39.13	4.00e-70	257.00
IUUC-Cja-019741	Callithrix jacchus	47.87	6.00e-85	306.00
IUUC-Cfa-021204	Canis familiaris	47.71	3.00e-84	303.00
IUUC-Cpo-021661	Cavia porcellus	47.40	7.00e-84	303.00
IUUC-Cre-022952	Chlamydomonas reinhardtii	53.37	2.00e-105	374.00
IUUC-Csa-024038	Chlorocebus sabaeus	47.87	6.00e-85	306.00
IUUC-Cin-025597	Ciona intestinalis	45.09	2.00e-82	298.00
IUUC-Cgl-026583	Colletotrichum gloeosporioides	43.69	3.00e-75	274.00
IUUC-Cne-026838	Cryptococcus neoformans	42.25	5.00e-76	276.00
IUUC-Cme-027304	Cyanidioschyzon merolae	53.09	7.00e-90	322.00
IUUC-Dre-028567	Danio rerio	46.01	2.00e-87	314.00
IUUC-Dno-029171	Dasypus novemcinctus	47.71	2.00e-83	302.00
IUUC-Dor-030257	Dipodomys ordii	34.83	3.00e-26	111.00
IUUC-Dse-031191	Dothistroma septosporum	44.11	5.00e-76	276.00
IUUC-Dme-031879	Drosophila melanogaster	48.61	9.00e-90	322.00
IUUC-Ete-032336	Echinops telfairi	41.10	4.00e-40	156.00
IUUC-Eca-033259	Equus caballus	47.71	4.00e-84	303.00
IUUC-Eeu-035153	Erinaceus europaeus	43.80	2.00e-25	108.00
IUUC-Fca-036489	Felis catus	47.71	4.00e-84	303.00
IUUC-Fal-037485	Ficedula albicollis	46.77	2.00e-85	308.00
IUUC-Fox-037860	Fusarium oxysporum	44.62	1.00e-76	279.00
IUUC-Fso-038188	Fusarium solani	44.62	5.00e-77	280.00
IUUC-Gmo-039311	Gadus morhua	45.23	4.00e-85	307.00
IUUC-Ggr-040045	Gaeumannomyces graminis	43.90	7.00e-78	283.00
IUUC-Gga-040645	Gallus gallus	46.11	2.00e-84	304.00
IUUC-Gac-042086	Gasterosteus aculeatus	46.01	5.00e-85	306.00
IUUC-Gma-043246	Glycine max	93.87	0.00e+00	645.00
IUUC-Ggo-045578	Gorilla gorilla	47.87	6.00e-85	306.00
IUUC-Hsa-046734	Homo sapiens	47.87	6.00e-85	306.00
IUUC-Hvu-047553	Hordeum vulgare	81.29	6.00e-160	555.00
IUUC-Itr-048467	Ictidomys tridecemlineatus	47.71	5.00e-84	303.00
IUUC-Kpa-049325	Komagataella pastoris	44.34	2.00e-78	285.00
IUUC-Lch-049620	Latimeria chalumnae	46.18	2.00e-77	281.00
IUUC-Lpe-051338	Leersia perrieri	78.53	1.00e-148	517.00
IUUC-Loc-052094	Lepisosteus oculatus	43.12	2.00e-72	265.00
IUUC-Lma-053047	Leptosphaeria maculans	47.69	5.00e-83	300.00
IUUC-Laf-053801	Loxodonta africana	47.66	1.00e-81	295.00
IUUC-Mcc-055498	Macaca mulatta	42.99	2.00e-66	244.00
IUUC-Meu-056729	Macropus eugenii	44.38	2.00e-76	278.00
IUUC-Mor-057025	Magnaporthe oryzae	44.79	2.00e-76	278.00
IUUC-Mpo-057511	Magnaporthe poae	45.09	9.00e-78	282.00
IUUC-Mtr-058051	Medicago truncatula	92.33	0.00e+00	637.00
IUUC-Mla-059061	Melampsora laricipopulina	44.17	2.00e-77	281.00
IUUC-Mga-059229	Meleagris gallopavo	46.48	3.00e-83	301.00
IUUC-Mvi-060399	Microbotryum violaceum	44.35	1.00e-76	278.00
IUUC-Mmr-060764	Microcebus murinus	47.87	4.00e-85	307.00
IUUC-Mdo-062088	Monodelphis domestica	47.26	4.00e-85	306.00
IUUC-Mmu-064304	Mus musculus	47.56	5.00e-85	306.00
IUUC-Mac-065520	Musa acuminata	84.74	1.00e-168	584.00
IUUC-Mpu-066340	Mustela putorius furo	47.71	4.00e-84	303.00
IUUC-Mlu-067111	Myotis lucifugus	47.71	3.00e-84	304.00
IUUC-Nfi-068478	Neosartorya fischeri	45.02	1.00e-77	282.00
IUUC-Ncr-068820	Neurospora crassa	45.54	2.00e-77	281.00
IUUC-Nle-069903	Nomascus leucogenys	47.71	2.00e-84	304.00
IUUC-Opr-070221	Ochotona princeps	46.65	2.00e-82	298.00
IUUC-Ont-071765	Oreochromis niloticus	46.93	9.00e-89	319.00
IUUC-Oan-073660	Ornithorhynchus anatinus	46.08	5.00e-72	263.00
IUUC-Ocu-074039	Oryctolagus cuniculus	47.71	3.00e-84	304.00
IUUC-Oba-075395	Oryza barthii	75.77	4.00e-145	506.00
IUUC-Obr-076334	Oryza brachyantha	77.91	8.00e-152	528.00
IUUC-Ogl-077751	Oryza glaberrima	82.52	8.00e-163	565.00
IUUC-Ogu-078207	Oryza glumaepatula	80.92	1.00e-158	551.00
IUUC-Oin-079878	Oryza indica	81.60	4.00e-160	556.00
IUUC-Olo-080677	Oryza longistaminata	68.68	1.00e-147	514.00
IUUC-Ome-081228	Oryza meridionalis	62.66	1.00e-80	291.00
IUUC-Oni-082411	Oryza nivara	73.31	4.00e-138	483.00
IUUC-Opu-083136	Oryza punctata	82.21	3.00e-162	563.00
IUUC-Oru-084916	Oryza rufipogon	79.40	2.00e-158	550.00
IUUC-Osa-085776	Oryza sativa	82.52	8.00e-163	565.00
IUUC-Ola-087053	Oryzias latipes	47.87	1.00e-86	312.00
IUUC-Olu-087602	Ostreococcus lucimarinus	62.46	5.00e-125	439.00
IUUC-Oga-088154	Otolemur garnettii	48.01	6.00e-85	306.00
IUUC-Oar-089915	Ovis aries	46.77	5.00e-84	303.00
IUUC-Ptr-091124	Pan troglodytes	37.96	1.00e-56	212.00
IUUC-Pan-092035	Papio anubis	47.87	6.00e-85	306.00
IUUC-Psi-094096	Pelodiscus sinensis	49.75	6.00e-51	192.00
IUUC-Pno-094988	Phaeosphaeria nodorum	44.62	1.00e-72	265.00
IUUC-Ppa-095949	Physcomitrella patens	76.07	5.00e-155	539.00
IUUC-Pfo-096101	Poecilia formosa	46.01	5.00e-87	313.00
IUUC-Pab-097726	Pongo abelii	47.87	6.00e-85	306.00
IUUC-Pop-099617	Populus trichocarpa	87.12	2.00e-174	603.00
IUUC-Pca-101014	Procavia capensis	47.87	5.00e-85	306.00
IUUC-Pva-102789	Pteropus vampyrus	43.87	3.00e-74	271.00
IUUC-Pgr-103479	Puccinia graminis	44.17	2.00e-77	281.00
IUUC-Ptt-103981	Puccinia triticina	44.17	1.00e-77	282.00
IUUC-Pte-104278	Pyrenophora teres	46.46	3.00e-80	290.00
IUUC-Pyt-104492	Pyrenophora triticirepentis	46.46	3.00e-80	290.00
IUUC-Rno-105867	Rattus norvegicus	44.82	4.00e-70	257.00
IUUC-Sce-106251	Saccharomyces cerevisiae	40.60	5.00e-71	260.00
IUUC-Sha-107039	Sarcophilus harrisii	47.26	5.00e-85	306.00
IUUC-Sja-107758	Schizosaccharomyces japonicus	43.73	6.00e-81	293.00
IUUC-Spo-108314	Schizosaccharomyces pombe	44.17	9.00e-85	305.00
IUUC-Ssl-108478	Sclerotinia sclerotiorum	44.65	3.00e-79	287.00
IUUC-Smo-108728	Selaginella moellendorffii	75.38	3.00e-150	523.00
IUUC-Sit-110801	Setaria italica	80.98	7.00e-160	555.00
IUUC-Sly-111326	Solanum lycopersicum	87.73	1.00e-176	610.00
IUUC-Stu-112458	Solanum tuberosum	89.26	1.00e-178	617.00
IUUC-Sbi-114063	Sorghum bicolor	80.37	4.00e-159	552.00
IUUC-Sre-115096	Sporisorium reilianum	43.49	4.00e-73	267.00
IUUC-Ssc-116080	Sus scrofa	47.87	8.00e-85	306.00
IUUC-Tgu-116988	Taeniopygia guttata	46.77	2.00e-85	308.00
IUUC-Tru-118766	Takifugu rubripes	46.32	3.00e-87	313.00
IUUC-Tni-120197	Tetraodon nigroviridis	46.63	1.00e-87	315.00
IUUC-Tca-121316	Theobroma cacao	90.80	0.00e+00	625.00
IUUC-Tre-122097	Trichoderma reesei	44.95	2.00e-78	285.00
IUUC-Tvi-122442	Trichoderma virens	44.95	9.00e-78	282.00
IUUC-Tae-125800	Triticum aestivum	81.60	3.00e-160	556.00
IUUC-Tur-126334	Triticum urartu	72.09	2.00e-134	471.00
IUUC-Tme-127038	Tuber melanosporum	45.87	1.00e-82	298.00
IUUC-Ttr-128659	Tursiops truncatus	43.60	4.00e-64	237.00
IUUC-Uma-129464	Ustilago maydis	44.08	2.00e-73	268.00
IUUC-Vda-129841	Verticillium dahliae	44.92	8.00e-77	279.00
IUUC-Vvi-131076	Vitis vinifera	89.88	0.00e+00	625.00
IUUC-Xtr-132395	Xenopus tropicalis	46.32	1.00e-86	312.00
IUUC-Xma-133383	Xiphophorus maculatus	46.01	8.00e-87	312.00
IUUC-Yli-134586	Yarrowia lipolytica	43.12	1.00e-68	252.00
IUUC-Zma-135667	Zea mays	80.67	3.00e-160	556.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence