iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062826

Ensembl Protein ID

ENSMODP00000017666.2

UniProt Accession

F6XLL0; F6XLL0_MONDO

Protein Name

Histone acetyltransferase

Gene Name

KAT6A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000010328.5	ENSMODT00000017994.2	ENSMODP00000017666.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	6.10e-11	42.5	263	312

Active Site

Position(s)	Description	Evidence
590	Proton donor/acceptor	{ECO:0000256\|PIRSR:PIRSR602717-51}

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           k C  C+++g++ ++++ C+ C++ fH +C  ++  + +p+   wiC+ Cr 
   Q: 263  KTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPP-LTRMPKGM-WICQICRP 312
           68999******99*********************.9*****97.******85 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MVKLANPLYT EWILEAIKKV KKQKQRPSEE RICNAVSSSH GLDRKTVLEQ LELSVKDGTI 60
LKVSNKGLNS YKDPDNPGRI ALPKPRNHGK LDGKQNVDWN KLIKRAVEGL AESSGSTLKN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTAAAAC TCGCTAACCC GCTGTATACG GAGTGGATTT TGGAGGCGAT CAAAAAAGTA 60
AAGAAGCAAA AACAGCGTCC TTCAGAAGAG AGGATATGCA ATGCGGTGTC TTCATCCCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016181--Acyl_CoA_acyltransferase
IPR002717--HAT_MYST-type
IPR005818--Histone_H1/H5_H15
IPR031280--KAT6A
IPR011991--WHTH_DNA-bd_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51504--H15
PS51726--MYST_HAT
PS50016--ZF_PHD_2

Pfam

PF01853--MOZ_SAS
PF00628--PHD

SMART

SM00526--H15
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0016607--C:nuclear speck
GO:0005730--C:nucleolus
GO:0000786--C:nucleosome
GO:0016605--C:PML body
GO:0003677--F:DNA binding
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0090398--P:cellular senescence
GO:0043966--P:histone H3 acetylation
GO:0030099--P:myeloid cell differentiation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0006334--P:nucleosome assembly
GO:0045893--P:positive regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001219	Ailuropoda melanoleuca	91.34	0.00e+00	976.00
IUUC-Aca-004549	Anolis carolinensis	90.84	0.00e+00	673.00
IUUC-Ame-010711	Astyanax mexicanus	78.80	1.00e-162	568.00
IUUC-Bta-013426	Bos taurus	74.78	0.00e+00	673.00
IUUC-Cja-019124	Callithrix jacchus	93.18	0.00e+00	879.00
IUUC-Cfa-021165	Canis familiaris	94.23	0.00e+00	698.00
IUUC-Cpo-022332	Cavia porcellus	74.82	0.00e+00	1642.00
IUUC-Cne-026801	Cryptococcus neoformans	52.82	1.00e-55	211.00
IUUC-Dre-028624	Danio rerio	75.14	8.00e-160	558.00
IUUC-Dno-029878	Dasypus novemcinctus	74.79	0.00e+00	1154.00
IUUC-Ete-032342	Echinops telfairi	93.68	0.00e+00	687.00
IUUC-Eca-033925	Equus caballus	92.86	0.00e+00	682.00
IUUC-Fca-035985	Felis catus	94.23	0.00e+00	697.00
IUUC-Gmo-039182	Gadus morhua	78.10	3.00e-160	560.00
IUUC-Gga-041028	Gallus gallus	88.66	0.00e+00	877.00
IUUC-Gac-042131	Gasterosteus aculeatus	75.22	2.00e-155	544.00
IUUC-Ggo-044664	Gorilla gorilla	69.44	0.00e+00	754.00
IUUC-Hsa-046832	Homo sapiens	69.31	0.00e+00	751.00
IUUC-Loc-052537	Lepisosteus oculatus	81.32	4.00e-169	589.00
IUUC-Laf-053686	Loxodonta africana	93.96	0.00e+00	688.00
IUUC-Mcc-055429	Macaca mulatta	69.18	0.00e+00	753.00
IUUC-Mvi-060531	Microbotryum violaceum	48.90	4.00e-55	210.00
IUUC-Mmr-061249	Microcebus murinus	68.26	0.00e+00	782.00
IUUC-Mmu-063474	Mus musculus	65.21	0.00e+00	783.00
IUUC-Mpu-066585	Mustela putorius furo	94.23	0.00e+00	694.00
IUUC-Mlu-066965	Myotis lucifugus	93.13	0.00e+00	694.00
IUUC-Nle-069270	Nomascus leucogenys	69.18	0.00e+00	757.00
IUUC-Opr-070963	Ochotona princeps	95.11	0.00e+00	686.00
IUUC-Ont-071466	Oreochromis niloticus	78.31	3.00e-163	570.00
IUUC-Oan-073367	Ornithorhynchus anatinus	94.49	0.00e+00	697.00
IUUC-Ocu-074100	Oryctolagus cuniculus	92.31	0.00e+00	676.00
IUUC-Ola-087293	Oryzias latipes	77.56	4.00e-159	555.00
IUUC-Oga-089052	Otolemur garnettii	93.54	0.00e+00	907.00
IUUC-Oar-089692	Ovis aries	93.13	0.00e+00	651.00
IUUC-Ptr-091107	Pan troglodytes	69.84	0.00e+00	758.00
IUUC-Pan-092524	Papio anubis	93.50	0.00e+00	886.00
IUUC-Pfo-096641	Poecilia formosa	72.07	2.00e-159	558.00
IUUC-Pab-098311	Pongo abelii	68.87	0.00e+00	757.00
IUUC-Pca-100810	Procavia capensis	67.95	3.00e-162	566.00
IUUC-Ppe-101709	Prunus persica	28.75	8.00e-13	68.90
IUUC-Pgr-103522	Puccinia graminis	44.58	3.00e-52	201.00
IUUC-Pyt-104594	Pyrenophora triticirepentis	32.10	2.00e-32	134.00
IUUC-Rno-104990	Rattus norvegicus	69.79	0.00e+00	1063.00
IUUC-Sha-106816	Sarcophilus harrisii	80.22	0.00e+00	1215.00
IUUC-Sre-115066	Sporisorium reilianum	48.09	1.00e-59	225.00
IUUC-Tgu-116639	Taeniopygia guttata	81.05	0.00e+00	966.00
IUUC-Tru-118571	Takifugu rubripes	74.86	7.00e-161	562.00
IUUC-Tni-119936	Tetraodon nigroviridis	78.22	3.00e-164	573.00
IUUC-Tbe-127928	Tupaia belangeri	93.97	0.00e+00	681.00
IUUC-Uma-129445	Ustilago maydis	48.09	1.00e-59	225.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence