iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034413

UUCD1 version

UUC-EqC-01002

Ensembl Protein ID

ENSECAP00000019547.1

UniProt Accession

F6XEX4; F6XEX4_HORSE

Protein Name

Uncharacterized protein

Gene Name

OTUD7A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000022071.1	ENSECAT00000023588.1	ENSECAP00000019547.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	1.70e-40	138.7	201	382

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqsllgvfddds.lsdalveaLreltseylqkesdffsefieek...........edekefcqklvepe.... 74
           l+l+t+gDGnCLl+A+s +++g++d+d+ l++al++++r+ +++++ k+++++++++++k           e+e++++ kl+++e    
   Q: 201  LPLATTGDGNCLLHAASLGMWGFHDRDLvLRKALYTMMRTGAEREALKRRWRWQQTQQNKesglvyteeewEREWTELLKLASSEprth 289
           6899*********************************************************************************8877 PP
   S: 75   .ak.g.................eeihifaLaqiLsrpiivvdvdsles.........kvggillpllfpeek.lkkpivLlYrsgHYda 134
            +k g                 ee+h+f+La+iL+rpi+vv++++l++         ++ggi+lpl++p+++ +++p+vL+Y+++H++a
   Q: 290  fSKnGgtgggvdnsedpvyeslEEFHVFVLAHILRRPIVVVADTMLRDsggeafapiPFGGIYLPLEVPPNRcHCSPLVLAYDQAHFSA 378
           7444377899******************************************************************************* PP
   S: 135  Lval 138
           Lv++
   Q: 379  LVSM 382
           *986 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MVSSLLPNPT SAECWAALLH DHMTLDMDAV LSDFVRSTGA EPGLARDLLE GKNWDLTAAL 60
SDYEQLRQVH TANLPHVFNE GRCPKQPERE PPQPGHKGER PCLQRQDDIA QEKRLSRGIS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGTGGAAG TGACAAAAGA GGAGACTCTC CCGGCCGAGG CTCCGGTGCA TGGAGAGAAG 60
GAAGAAGACA ATCTCCTAAT TGGTACCATA TACATCAGGT CAAATGATTT TCTTATTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom

PROSITE

PS50802--OTU

Pfam

PF02338--OTU

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0070530--F:K63-linked polyubiquitin binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006955--P:immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0071947--P:protein deubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0050727--P:regulation of inflammatory response
GO:0045088--P:regulation of innate immune response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001551	Ailuropoda melanoleuca	98.53	0.00e+00	1006.00
IUUC-Apl-003825	Anas platyrhynchos	86.14	0.00e+00	997.00
IUUC-Aca-004392	Anolis carolinensis	88.04	0.00e+00	1006.00
IUUC-Ame-011052	Astyanax mexicanus	83.00	0.00e+00	956.00
IUUC-Bta-013296	Bos taurus	96.57	0.00e+00	975.00
IUUC-Cja-019141	Callithrix jacchus	95.51	0.00e+00	1045.00
IUUC-Cfa-020447	Canis familiaris	97.73	0.00e+00	1092.00
IUUC-Cpo-022059	Cavia porcellus	96.46	0.00e+00	982.00
IUUC-Csa-023263	Chlorocebus sabaeus	98.19	0.00e+00	1083.00
IUUC-Cho-024611	Choloepus hoffmanni	87.28	4.00e-167	581.00
IUUC-Dre-028617	Danio rerio	81.08	0.00e+00	929.00
IUUC-Dno-029121	Dasypus novemcinctus	91.04	0.00e+00	993.00
IUUC-Ete-033068	Echinops telfairi	87.07	0.00e+00	930.00
IUUC-Fca-036487	Felis catus	92.43	0.00e+00	995.00
IUUC-Fal-037145	Ficedula albicollis	90.56	0.00e+00	999.00
IUUC-Gmo-038786	Gadus morhua	71.58	0.00e+00	812.00
IUUC-Gga-040512	Gallus gallus	88.91	0.00e+00	1008.00
IUUC-Gac-041599	Gasterosteus aculeatus	79.04	0.00e+00	909.00
IUUC-Ggo-044819	Gorilla gorilla	98.05	0.00e+00	988.00
IUUC-Hsa-046781	Homo sapiens	97.13	0.00e+00	1066.00
IUUC-Lch-050666	Latimeria chalumnae	86.63	0.00e+00	958.00
IUUC-Loc-052841	Lepisosteus oculatus	82.80	0.00e+00	962.00
IUUC-Laf-053437	Loxodonta africana	90.00	0.00e+00	1072.00
IUUC-Mcc-055353	Macaca mulatta	96.98	0.00e+00	1064.00
IUUC-Mga-059741	Meleagris gallopavo	88.98	0.00e+00	1010.00
IUUC-Mmr-061437	Microcebus murinus	97.13	0.00e+00	1128.00
IUUC-Mdo-061907	Monodelphis domestica	92.34	0.00e+00	1075.00
IUUC-Mmu-064074	Mus musculus	95.18	0.00e+00	1058.00
IUUC-Mpu-066004	Mustela putorius furo	95.42	0.00e+00	978.00
IUUC-Nle-069182	Nomascus leucogenys	98.19	0.00e+00	1082.00
IUUC-Opr-070701	Ochotona princeps	89.36	0.00e+00	850.00
IUUC-Ont-072431	Oreochromis niloticus	88.24	0.00e+00	862.00
IUUC-Oan-073235	Ornithorhynchus anatinus	84.38	0.00e+00	917.00
IUUC-Ocu-073935	Oryctolagus cuniculus	96.53	0.00e+00	1014.00
IUUC-Ola-087026	Oryzias latipes	80.18	0.00e+00	947.00
IUUC-Oga-088249	Otolemur garnettii	96.25	0.00e+00	1102.00
IUUC-Oar-089476	Ovis aries	96.53	0.00e+00	1072.00
IUUC-Ptr-090548	Pan troglodytes	98.59	0.00e+00	1041.00
IUUC-Pan-092616	Papio anubis	97.33	0.00e+00	1019.00
IUUC-Psi-093126	Pelodiscus sinensis	90.91	0.00e+00	1021.00
IUUC-Pfo-096785	Poecilia formosa	79.75	0.00e+00	914.00
IUUC-Pab-098336	Pongo abelii	98.19	0.00e+00	1082.00
IUUC-Pca-100206	Procavia capensis	88.54	0.00e+00	876.00
IUUC-Sha-106617	Sarcophilus harrisii	89.32	0.00e+00	924.00
IUUC-Ssc-115415	Sus scrofa	96.41	0.00e+00	961.00
IUUC-Tgu-117218	Taeniopygia guttata	87.36	0.00e+00	1004.00
IUUC-Tru-118720	Takifugu rubripes	86.52	0.00e+00	836.00
IUUC-Tni-120795	Tetraodon nigroviridis	80.81	0.00e+00	898.00
IUUC-Xtr-132158	Xenopus tropicalis	81.28	0.00e+00	1003.00
IUUC-Xma-133941	Xiphophorus maculatus	78.07	0.00e+00	875.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence