iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037643

Ensembl Protein ID

ENSFALP00000011478.1

UniProt Accession

U3K8X4; U3K8X4_FICAL

Genbank Protein ID

ENSFALP00000011478

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01011165

Gene Name

USP34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000010997.1	ENSFALT00000011524.1	ENSFALP00000011478.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.00e-69	234.0	1899	2244

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           +Gl+Nlg+tCY+ S++Q+L++ipe r+++++ k++e++       ++++ l +lqk+f+ l++s+ ka++pr + k+  + ++ +++
   Q: 1899 VGLTNLGATCYLASTIQQLYMIPEARQAIFTaKYSEDM-------KHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNT 1978
           6******************************3444444.......4568899*********************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
            eq+D  Ef++ l+ ++ee                               + k++++ lF+g ++++++ l+c++vs++ e+f+++ 
   Q: 1979 GEQKDMTEFFTDLITKIEEMS----------------------------PELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVR 2037
           *****************9977............................567899******************************** PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLd 260
           ++v + +     ++ ++L++ t +++leg+n+y c++c kk++aek+  +kklP++L+++ +R++f+  ++++ek+n++++fpl+Ld
   Q: 2038 CQVADMK-----NIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLD 2119
           *******.....9************************************************************************** PP
   S: 261  lspfcts................peekqke.....kkkYeLiavvvHsGslssGHYvayvkn.......ekgkWllfdDskVtevke 319
           ++p++++                            +++Y+Li+v vH+G++++GHY++++++       +++kW+lf+D +V++ + 
   Q: 2120 MTPYTEDflmgkndrkegfkedgG-----YlketeSYEYDLIGVTVHTGTADGGHYYSFIRDivnphayKNNKWYLFNDAEVKPFDS 2201
           ******988887777766666662.....0444449**************************99999988999************** PP
   S: 320  eevleetg........................staYvlfYkrr 338
           ++  +e+                         ++aY+lfYkr+
   Q: 2202 AQLASECFggemttktydsvtdkfmdfsfektHSAYMLFYKRM 2244
           ****97779********************************96 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MLGLFPSNML VLLFSLVSDI EGGDALQLRK EHALKIFAYI NSWTQRQCLC CFKEYKHLEI 60
FNQVVCALIN LVIAQVQALR DQLCKHCTIN IDSPWPEQSN HADEPLNVER ESHEEENGER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAACAGAAC AATTGCATGT TGGGTCTTTT TCCTTCTAAC ATGTTGGTGC TTTTGTTTTC 60
TTTAGTATCA GACATTGAAG GTGGTGATGC TTTGCAGCTC AGAAAGGAAC ATGCCCTCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0732--Signal

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0071108--P:protein K48-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002257	Ailuropoda melanoleuca	92.61	0.00e+00	6489.00
IUUC-Apl-003284	Anas platyrhynchos	96.21	0.00e+00	6415.00
IUUC-Aca-004415	Anolis carolinensis	93.23	0.00e+00	6511.00
IUUC-Acl-008140	Aspergillus clavatus	28.87	7.00e-64	240.00
IUUC-Afl-008381	Aspergillus flavus	29.04	3.00e-63	238.00
IUUC-Afu-008857	Aspergillus fumigatus	28.00	1.00e-64	242.00
IUUC-Ani-009257	Aspergillus nidulans	27.42	1.00e-55	213.00
IUUC-Ang-009759	Aspergillus niger	27.89	4.00e-63	237.00
IUUC-Aor-009931	Aspergillus oryzae	29.04	2.00e-63	238.00
IUUC-Ate-010246	Aspergillus terreus	29.30	2.00e-53	205.00
IUUC-Ame-011219	Astyanax mexicanus	63.71	0.00e+00	2472.00
IUUC-Bgr-012195	Blumeria graminis	27.04	2.00e-65	245.00
IUUC-Bta-012989	Bos taurus	92.07	0.00e+00	6436.00
IUUC-Bci-013798	Botrytis cinerea	33.17	6.00e-58	220.00
IUUC-Cja-018974	Callithrix jacchus	84.73	0.00e+00	698.00
IUUC-Cfa-021214	Canis familiaris	92.61	0.00e+00	6495.00
IUUC-Cpo-021912	Cavia porcellus	93.78	0.00e+00	4543.00
IUUC-Csa-023658	Chlorocebus sabaeus	92.02	0.00e+00	6440.00
IUUC-Cho-024971	Choloepus hoffmanni	77.98	0.00e+00	3016.00
IUUC-Cgl-026466	Colletotrichum gloeosporioides	28.84	7.00e-64	240.00
IUUC-Dre-027428	Danio rerio	85.05	0.00e+00	4667.00
IUUC-Dno-029690	Dasypus novemcinctus	91.86	0.00e+00	6337.00
IUUC-Dor-030817	Dipodomys ordii	91.20	0.00e+00	1449.00
IUUC-Dse-031423	Dothistroma septosporum	25.60	1.00e-35	146.00
IUUC-Dme-032102	Drosophila melanogaster	54.27	0.00e+00	852.00
IUUC-Ete-032552	Echinops telfairi	87.33	0.00e+00	2836.00
IUUC-Eca-033457	Equus caballus	93.21	0.00e+00	6254.00
IUUC-Eeu-035118	Erinaceus europaeus	87.26	0.00e+00	2899.00
IUUC-Fca-036213	Felis catus	90.92	0.00e+00	4847.00
IUUC-Fox-037971	Fusarium oxysporum	27.54	3.00e-62	234.00
IUUC-Fso-038108	Fusarium solani	27.38	5.00e-59	224.00
IUUC-Ggr-040075	Gaeumannomyces graminis	32.16	5.00e-61	230.00
IUUC-Gga-040511	Gallus gallus	95.94	0.00e+00	6710.00
IUUC-Gac-042024	Gasterosteus aculeatus	89.11	0.00e+00	5061.00
IUUC-Ggo-044924	Gorilla gorilla	88.85	0.00e+00	5954.00
IUUC-Hsa-046913	Homo sapiens	92.07	0.00e+00	6479.00
IUUC-Itr-048626	Ictidomys tridecemlineatus	92.33	0.00e+00	6477.00
IUUC-Lch-049675	Latimeria chalumnae	87.76	0.00e+00	4956.00
IUUC-Loc-052832	Lepisosteus oculatus	86.71	0.00e+00	5975.00
IUUC-Lma-053130	Leptosphaeria maculans	27.30	4.00e-59	224.00
IUUC-Laf-054169	Loxodonta africana	91.89	0.00e+00	6470.00
IUUC-Mcc-055847	Macaca mulatta	91.25	0.00e+00	6354.00
IUUC-Meu-056327	Macropus eugenii	81.78	0.00e+00	1556.00
IUUC-Mor-057152	Magnaporthe oryzae	28.15	6.00e-61	230.00
IUUC-Mpo-057310	Magnaporthe poae	26.58	7.00e-60	227.00
IUUC-Mmr-060780	Microcebus murinus	92.27	0.00e+00	6478.00
IUUC-Mdo-062308	Monodelphis domestica	91.21	0.00e+00	6100.00
IUUC-Mmu-063457	Mus musculus	90.69	0.00e+00	6398.00
IUUC-Mpu-066917	Mustela putorius furo	90.29	0.00e+00	6267.00
IUUC-Mlu-067696	Myotis lucifugus	92.33	0.00e+00	6452.00
IUUC-Nfi-068259	Neosartorya fischeri	27.24	4.00e-64	241.00
IUUC-Ncr-068911	Neurospora crassa	25.62	3.00e-59	225.00
IUUC-Nle-069586	Nomascus leucogenys	92.08	0.00e+00	6496.00
IUUC-Opr-070447	Ochotona princeps	86.86	0.00e+00	2720.00
IUUC-Ont-072396	Oreochromis niloticus	84.35	0.00e+00	5504.00
IUUC-Oan-073147	Ornithorhynchus anatinus	93.75	0.00e+00	6544.00
IUUC-Ocu-074324	Oryctolagus cuniculus	92.28	0.00e+00	6452.00
IUUC-Ola-086312	Oryzias latipes	82.39	0.00e+00	5336.00
IUUC-Oga-088878	Otolemur garnettii	92.28	0.00e+00	6467.00
IUUC-Oar-089919	Ovis aries	92.05	0.00e+00	6438.00
IUUC-Ptr-090713	Pan troglodytes	93.21	0.00e+00	6029.00
IUUC-Pan-091957	Papio anubis	93.05	0.00e+00	4894.00
IUUC-Psi-093240	Pelodiscus sinensis	94.73	0.00e+00	6603.00
IUUC-Pma-094469	Petromyzon marinus	72.52	0.00e+00	4093.00
IUUC-Pno-095059	Phaeosphaeria nodorum	29.66	6.00e-56	213.00
IUUC-Pfo-097159	Poecilia formosa	82.16	0.00e+00	5555.00
IUUC-Pab-098003	Pongo abelii	92.12	0.00e+00	6173.00
IUUC-Pca-100799	Procavia capensis	95.77	0.00e+00	1468.00
IUUC-Pva-103226	Pteropus vampyrus	87.65	0.00e+00	6055.00
IUUC-Pte-104235	Pyrenophora teres	32.86	6.00e-59	223.00
IUUC-Pyt-104803	Pyrenophora triticirepentis	27.35	7.00e-60	226.00
IUUC-Rno-105389	Rattus norvegicus	91.41	0.00e+00	5329.00
IUUC-Sha-106979	Sarcophilus harrisii	93.05	0.00e+00	6492.00
IUUC-Sar-113444	Sorex araneus	85.91	0.00e+00	5658.00
IUUC-Ssc-115815	Sus scrofa	94.01	0.00e+00	5447.00
IUUC-Tgu-117470	Taeniopygia guttata	96.40	0.00e+00	6395.00
IUUC-Tru-118543	Takifugu rubripes	81.84	0.00e+00	5393.00
IUUC-Tsy-119081	Tarsius syrichta	84.64	0.00e+00	4676.00
IUUC-Tni-120294	Tetraodon nigroviridis	83.25	4.00e-164	570.00
IUUC-Tre-122057	Trichoderma reesei	29.38	7.00e-60	227.00
IUUC-Tvi-122570	Trichoderma virens	35.62	7.00e-59	223.00
IUUC-Tme-127154	Tuber melanosporum	28.02	2.00e-60	228.00
IUUC-Tbe-127801	Tupaia belangeri	92.60	0.00e+00	2239.00
IUUC-Ttr-129262	Tursiops truncatus	88.21	0.00e+00	6111.00
IUUC-Vda-129686	Verticillium dahliae	28.55	7.00e-61	230.00
IUUC-Vpa-130484	Vicugna pacos	88.46	0.00e+00	6058.00
IUUC-Xtr-131769	Xenopus tropicalis	86.07	0.00e+00	6073.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence