iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gga-040806

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AADN04000106

Gene Name

RFWD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000004500.5	ENSGALT00000007170.5	ENSGALP00000007158.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.50e-06	28.3	112	150
E3 adaptor/Cullin RING/DCX/DWD	4.00e-24	84.1	446	475

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC++++++  + + CgH f+ +C+++          + rCP C+
   Q: 112  CPICFDMIEE-AYMTKCGHSFCYKCIHQS------LEDNNRCPKCN 150
           ********99.888***********9555......999999****6 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 3    tdsvtclaf..sd.tllvsGsdDgtikvWD 29
           +++++c+++     +ll+s+ + gt+ +WD
   Q: 446  NSKISCISWssYHkNLLASSDYEGTVILWD 475
           689******9622599************** PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MSGSRPPPHP AAPPAAPASS SSSSSSSSAA MAPGSSSSGG AAARPVLVAA AVSGSGAAAG 60
AGLARLAAAA RPGGGSSGGG GAGGGGRKRP LLTPLCNGLL NSYEDKSNDF VCPICFDMIE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCCCCGCCG CGGGCGGCGC ATGCGCGGCG GCGTGTCCGC CTGTCAATAA AGATTGAACA 60
AGCGCCGGGC CGGGGGCGCG CGGGCGGGCG CGTTTTGTTG GGCTTTTTTT TTTTCTTCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00400--WD40

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0010212--P:response to ionizing radiation

KEGG

gga:429072

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000885	Aegilops tauschii	40.19	4.00e-127	448.00
IUUC-Aml-001265	Ailuropoda melanoleuca	98.54	0.00e+00	1237.00
IUUC-Atr-002460	Amborella trichopoda	38.77	8.00e-125	441.00
IUUC-Apl-003796	Anas platyrhynchos	99.14	0.00e+00	1167.00
IUUC-Aca-005078	Anolis carolinensis	98.07	0.00e+00	1214.00
IUUC-Aly-006014	Arabidopsis lyrata	39.82	8.00e-130	457.00
IUUC-Ath-007636	Arabidopsis thaliana	39.66	3.00e-129	455.00
IUUC-Ame-011176	Astyanax mexicanus	96.69	1.00e-69	256.00
IUUC-Bta-012595	Bos taurus	98.39	0.00e+00	1239.00
IUUC-Bdi-014152	Brachypodium distachyon	39.30	6.00e-129	454.00
IUUC-Bol-016380	Brassica oleracea	39.91	1.00e-130	459.00
IUUC-Bra-017690	Brassica rapa	39.24	6.00e-125	441.00
IUUC-Cja-018926	Callithrix jacchus	98.39	0.00e+00	1240.00
IUUC-Cfa-021088	Canis familiaris	98.23	0.00e+00	1241.00
IUUC-Cpo-022442	Cavia porcellus	97.37	0.00e+00	1200.00
IUUC-Cre-022579	Chlamydomonas reinhardtii	33.45	3.00e-33	135.00
IUUC-Csa-024119	Chlorocebus sabaeus	98.07	0.00e+00	1235.00
IUUC-Cho-024883	Choloepus hoffmanni	66.23	6.00e-106	378.00
IUUC-Cin-025375	Ciona intestinalis	55.71	0.00e+00	681.00
IUUC-Cme-027350	Cyanidioschyzon merolae	40.78	9.00e-80	291.00
IUUC-Dre-028453	Danio rerio	87.56	0.00e+00	1086.00
IUUC-Dno-029887	Dasypus novemcinctus	98.23	0.00e+00	1239.00
IUUC-Dor-031110	Dipodomys ordii	79.65	0.00e+00	921.00
IUUC-Ete-033016	Echinops telfairi	84.06	0.00e+00	1027.00
IUUC-Eca-034403	Equus caballus	98.27	0.00e+00	1152.00
IUUC-Eeu-034690	Erinaceus europaeus	81.34	0.00e+00	952.00
IUUC-Fca-036475	Felis catus	97.76	0.00e+00	1153.00
IUUC-Fal-037189	Ficedula albicollis	99.66	0.00e+00	1204.00
IUUC-Gmo-039245	Gadus morhua	86.79	0.00e+00	1061.00
IUUC-Gac-042177	Gasterosteus aculeatus	88.16	0.00e+00	1105.00
IUUC-Gma-044187	Glycine max	40.33	3.00e-126	445.00
IUUC-Ggo-044430	Gorilla gorilla	97.03	0.00e+00	919.00
IUUC-Hsa-045853	Homo sapiens	98.23	0.00e+00	1237.00
IUUC-Hvu-047750	Hordeum vulgare	39.34	1.00e-95	344.00
IUUC-Itr-048238	Ictidomys tridecemlineatus	98.75	7.00e-144	502.00
IUUC-Lch-050420	Latimeria chalumnae	92.20	0.00e+00	1154.00
IUUC-Lpe-051219	Leersia perrieri	38.85	1.00e-124	440.00
IUUC-Loc-052728	Lepisosteus oculatus	91.45	0.00e+00	1113.00
IUUC-Laf-053775	Loxodonta africana	97.73	0.00e+00	1238.00
IUUC-Meu-056595	Macropus eugenii	77.46	1.00e-176	613.00
IUUC-Mtr-058555	Medicago truncatula	40.80	9.00e-134	470.00
IUUC-Mga-059646	Meleagris gallopavo	99.14	0.00e+00	1169.00
IUUC-Mmr-060990	Microcebus murinus	98.54	0.00e+00	1237.00
IUUC-Mdo-062287	Monodelphis domestica	98.71	0.00e+00	1245.00
IUUC-Mmu-064097	Mus musculus	98.39	0.00e+00	1241.00
IUUC-Mac-065240	Musa acuminata	41.16	2.00e-135	476.00
IUUC-Mpu-066612	Mustela putorius furo	97.77	0.00e+00	1155.00
IUUC-Mlu-067967	Myotis lucifugus	95.98	0.00e+00	1156.00
IUUC-Nle-069543	Nomascus leucogenys	98.39	0.00e+00	1241.00
IUUC-Opr-070366	Ochotona princeps	82.71	0.00e+00	706.00
IUUC-Ont-071522	Oreochromis niloticus	87.84	0.00e+00	1096.00
IUUC-Oan-073409	Ornithorhynchus anatinus	98.28	0.00e+00	1154.00
IUUC-Ocu-073756	Oryctolagus cuniculus	98.17	0.00e+00	1206.00
IUUC-Oba-075149	Oryza barthii	38.67	5.00e-127	449.00
IUUC-Obr-076563	Oryza brachyantha	39.38	1.00e-127	449.00
IUUC-Ogl-077701	Oryza glaberrima	38.65	1.00e-127	450.00
IUUC-Ogu-078383	Oryza glumaepatula	38.65	1.00e-127	450.00
IUUC-Oin-079965	Oryza indica	36.78	3.00e-114	405.00
IUUC-Olo-080639	Oryza longistaminata	38.82	2.00e-125	442.00
IUUC-Ome-081821	Oryza meridionalis	38.21	2.00e-115	410.00
IUUC-Oni-082622	Oryza nivara	38.65	1.00e-127	450.00
IUUC-Opu-083295	Oryza punctata	38.65	2.00e-127	449.00
IUUC-Oru-084661	Oryza rufipogon	38.65	1.00e-127	450.00
IUUC-Osa-085766	Oryza sativa	38.65	1.00e-127	450.00
IUUC-Ola-086727	Oryzias latipes	87.82	0.00e+00	1113.00
IUUC-Olu-087702	Ostreococcus lucimarinus	42.99	4.00e-69	254.00
IUUC-Oga-088215	Otolemur garnettii	96.29	0.00e+00	1212.00
IUUC-Oar-089880	Ovis aries	98.34	0.00e+00	1206.00
IUUC-Ptr-090597	Pan troglodytes	98.23	0.00e+00	1237.00
IUUC-Pan-091987	Papio anubis	98.55	0.00e+00	1243.00
IUUC-Psi-094033	Pelodiscus sinensis	98.31	0.00e+00	1167.00
IUUC-Pma-094587	Petromyzon marinus	71.15	0.00e+00	805.00
IUUC-Ppa-095256	Physcomitrella patens	38.81	2.00e-133	469.00
IUUC-Pfo-097388	Poecilia formosa	86.84	0.00e+00	1074.00
IUUC-Pab-098029	Pongo abelii	98.23	0.00e+00	1238.00
IUUC-Pop-099319	Populus trichocarpa	39.17	6.00e-131	461.00
IUUC-Pca-100846	Procavia capensis	89.86	0.00e+00	1129.00
IUUC-Ppe-101250	Prunus persica	38.85	1.00e-119	423.00
IUUC-Pva-102407	Pteropus vampyrus	98.23	0.00e+00	1229.00
IUUC-Rno-105312	Rattus norvegicus	98.23	0.00e+00	1238.00
IUUC-Sha-106514	Sarcophilus harrisii	98.66	0.00e+00	769.00
IUUC-Smo-109418	Selaginella moellendorffii	40.93	7.00e-131	460.00
IUUC-Sit-110248	Setaria italica	38.86	3.00e-128	452.00
IUUC-Sly-110964	Solanum lycopersicum	40.34	9.00e-131	460.00
IUUC-Stu-112882	Solanum tuberosum	40.58	8.00e-132	464.00
IUUC-Sar-113230	Sorex araneus	71.53	0.00e+00	798.00
IUUC-Sbi-113962	Sorghum bicolor	37.13	2.00e-123	436.00
IUUC-Ssc-115987	Sus scrofa	97.14	3.00e-174	603.00
IUUC-Tgu-116471	Taeniopygia guttata	99.35	0.00e+00	1246.00
IUUC-Tru-118231	Takifugu rubripes	87.84	0.00e+00	1061.00
IUUC-Tsy-119415	Tarsius syrichta	97.82	0.00e+00	1162.00
IUUC-Tni-120893	Tetraodon nigroviridis	88.01	0.00e+00	1070.00
IUUC-Tca-121703	Theobroma cacao	41.05	1.00e-129	457.00
IUUC-Tae-125317	Triticum aestivum	41.23	1.00e-134	473.00
IUUC-Tur-126557	Triticum urartu	40.72	4.00e-130	458.00
IUUC-Tbe-127253	Tupaia belangeri	70.53	0.00e+00	840.00
IUUC-Ttr-129100	Tursiops truncatus	96.47	0.00e+00	1131.00
IUUC-Vpa-130613	Vicugna pacos	91.76	0.00e+00	1087.00
IUUC-Vvi-130880	Vitis vinifera	41.06	2.00e-123	436.00
IUUC-Xtr-132033	Xenopus tropicalis	95.49	0.00e+00	1233.00
IUUC-Xma-133421	Xiphophorus maculatus	86.68	0.00e+00	1070.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence