iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cin-025279

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

EAAA01000295

Gene Name

zf(traf/ring)-5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000001770.3	ENSCINT00000003578.3	ENSCINP00000003578.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.60e-34	113.9	421	452
UBD/Beta-Prp	3.90e-45	154.1	422	694

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrt 32
           gHt++v+cl+ ++++l sGs D++ikvWD+ t
   Q: 421  GHTGPVWCLCVHGDYLFSGSSDKQIKVWDTAT 452
           8********99559***************865 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttg.kllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           h++++ c+++  ++++l++gs d+ ikvwd+ t  k+ ++l+gh + v a++ + d   l +gs D tik+w+++t   + ++ +he+ 
   Q: 422  HTGPVWCLCV--HGDYLFSGSSDKQIKVWDTATNyKCQKTLEGHGGIVLALTAHGD--KLFSGSADCTIKIWSIDTLVELNSIAAHENP 506
           7888999***..******************86652779999*************99..6****************************** PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgq.cleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvy 184
           v++l      + l sGs  + i+vw++e++  ++++ l+g +++v+ +v +   ++l sGs+ +t+++Wd++t  +++ l+    +svy
   Q: 507  VCTLVCIN--NMLFSGS-LKSIKVWEVESDNlKFKQELEGLNHWVRALVAQH--DYLYSGSY-QTIKIWDVRTLACVHVLQT-SGGSVY 588
           ****9999..9******.9*********987245559***********9999..9******9.79***************99.****** PP
   S: 185  slsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs..pnderlvsgssDgsiriWdlrsgdllktlqlhnssvisva 271
           s++++    +++ g + +++ +wdl+t e v +l+gh   v+ ++++  p+++ + s+s D+s+r+W +++  +++tl +h+ sv++ a
   Q: 589  SIAVTN--HHILCGTYENSIHVWDLRTHEPVAQLTGHVGIVYALAVLstPEQTKVFSASYDRSLRVWSMENMICTQTLIRHQGSVVALA 675
           *****9..89************************************99999************************************** PP
   S: 272  vlsfgdnvlvlgsedskvniwk 293
           v   ++  +++g+ d +v++w+
   Q: 676  V---SRGRVFSGGVDFTVKVWQ 694
           9...999**************6 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

MSRYRFGSTR SPTSNDTENT PVPLRRSSAS VSGASRSRSS LFSQDGRAST PRLETTFGPS 60
FSTVTTITTD EGKVEYQHQR TTSMSSCKSF SDSREDLHGG STHSSLQRGI AATAQFNLFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAATGTCAT GTTCCTGCTG TTAGGTAACT TTCCATTCGG TTATGTCAAG ATATAGATTC 60
GGATCAACTC GTTCACCAAC CTCCAATGAT ACGGAGAACA CTCCTGTTCC ACTTCGTCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR033510--PLAA/Doa1/Lub1
IPR008974--TRAF-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR001293--Znf_TRAF

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00400--WD40
PF13445--zf-RING_UBOX

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001971	Ailuropoda melanoleuca	58.55	0.00e+00	770.00
IUUC-Apl-004098	Anas platyrhynchos	58.70	0.00e+00	773.00
IUUC-Aca-004852	Anolis carolinensis	54.29	1.00e-168	584.00
IUUC-Ame-011275	Astyanax mexicanus	50.97	2.00e-162	563.00
IUUC-Bta-013153	Bos taurus	58.98	0.00e+00	775.00
IUUC-Cja-019243	Callithrix jacchus	57.16	0.00e+00	746.00
IUUC-Cfa-020036	Canis familiaris	58.62	0.00e+00	777.00
IUUC-Cpo-022194	Cavia porcellus	58.76	0.00e+00	775.00
IUUC-Cre-022837	Chlamydomonas reinhardtii	40.28	3.00e-46	177.00
IUUC-Csa-023363	Chlorocebus sabaeus	57.91	0.00e+00	777.00
IUUC-Csv-026163	Ciona savignyi	89.07	0.00e+00	1050.00
IUUC-Dre-027998	Danio rerio	63.78	0.00e+00	739.00
IUUC-Dno-029356	Dasypus novemcinctus	47.77	8.00e-69	251.00
IUUC-Dor-030750	Dipodomys ordii	57.31	0.00e+00	758.00
IUUC-Eca-033671	Equus caballus	50.15	2.00e-172	597.00
IUUC-Eeu-034765	Erinaceus europaeus	73.36	1.00e-125	442.00
IUUC-Fca-035843	Felis catus	57.76	0.00e+00	776.00
IUUC-Fal-037237	Ficedula albicollis	58.76	0.00e+00	778.00
IUUC-Gmo-038779	Gadus morhua	53.26	0.00e+00	684.00
IUUC-Gga-040579	Gallus gallus	58.76	0.00e+00	776.00
IUUC-Gac-042233	Gasterosteus aculeatus	55.84	0.00e+00	745.00
IUUC-Gma-043481	Glycine max	25.21	6.00e-19	87.00
IUUC-Ggo-045147	Gorilla gorilla	57.91	0.00e+00	777.00
IUUC-Hsa-046117	Homo sapiens	57.91	0.00e+00	777.00
IUUC-Itr-048899	Ictidomys tridecemlineatus	57.63	0.00e+00	780.00
IUUC-Lch-050593	Latimeria chalumnae	57.74	0.00e+00	754.00
IUUC-Loc-052444	Lepisosteus oculatus	59.44	0.00e+00	791.00
IUUC-Laf-053499	Loxodonta africana	57.34	0.00e+00	759.00
IUUC-Mcc-055038	Macaca mulatta	57.91	0.00e+00	776.00
IUUC-Meu-056610	Macropus eugenii	50.20	1.00e-148	518.00
IUUC-Mtr-057641	Medicago truncatula	26.85	1.00e-19	89.70
IUUC-Mga-060183	Meleagris gallopavo	58.58	0.00e+00	770.00
IUUC-Mmr-061133	Microcebus murinus	55.13	0.00e+00	710.00
IUUC-Mdo-062312	Monodelphis domestica	57.40	0.00e+00	777.00
IUUC-Mmu-063844	Mus musculus	63.64	0.00e+00	753.00
IUUC-Mpu-066552	Mustela putorius furo	58.82	0.00e+00	771.00
IUUC-Mlu-067719	Myotis lucifugus	58.62	0.00e+00	749.00
IUUC-Nle-070045	Nomascus leucogenys	63.64	0.00e+00	753.00
IUUC-Opr-070927	Ochotona princeps	58.67	0.00e+00	771.00
IUUC-Ont-072680	Oreochromis niloticus	56.84	0.00e+00	753.00
IUUC-Oan-073521	Ornithorhynchus anatinus	82.00	2.00e-45	171.00
IUUC-Ola-087454	Oryzias latipes	57.06	0.00e+00	774.00
IUUC-Olu-087837	Ostreococcus lucimarinus	34.32	4.00e-35	139.00
IUUC-Oga-088380	Otolemur garnettii	58.62	0.00e+00	778.00
IUUC-Oar-089558	Ovis aries	52.50	0.00e+00	629.00
IUUC-Ptr-091606	Pan troglodytes	57.91	0.00e+00	777.00
IUUC-Pan-092227	Papio anubis	57.91	0.00e+00	776.00
IUUC-Psi-093853	Pelodiscus sinensis	52.23	2.00e-178	617.00
IUUC-Pma-094541	Petromyzon marinus	52.87	9.00e-104	368.00
IUUC-Pfo-096237	Poecilia formosa	62.48	0.00e+00	754.00
IUUC-Pab-097589	Pongo abelii	58.06	0.00e+00	779.00
IUUC-Pop-099181	Populus trichocarpa	27.84	8.00e-17	79.70
IUUC-Pca-100375	Procavia capensis	58.23	0.00e+00	738.00
IUUC-Ppe-101355	Prunus persica	26.94	1.00e-18	86.30
IUUC-Pva-102434	Pteropus vampyrus	58.77	0.00e+00	779.00
IUUC-Rno-105443	Rattus norvegicus	63.64	0.00e+00	755.00
IUUC-Sha-106517	Sarcophilus harrisii	57.46	0.00e+00	773.00
IUUC-Ssc-115990	Sus scrofa	58.62	0.00e+00	775.00
IUUC-Tgu-117222	Taeniopygia guttata	58.85	0.00e+00	775.00
IUUC-Tru-118392	Takifugu rubripes	57.06	0.00e+00	764.00
IUUC-Tni-120220	Tetraodon nigroviridis	56.78	0.00e+00	758.00
IUUC-Tca-121487	Theobroma cacao	26.85	7.00e-20	90.90
IUUC-Tur-126339	Triticum urartu	27.45	7.00e-17	80.50
IUUC-Tbe-128045	Tupaia belangeri	78.12	4.00e-129	453.00
IUUC-Ttr-128203	Tursiops truncatus	55.37	0.00e+00	733.00
IUUC-Vvi-131635	Vitis vinifera	27.57	2.00e-22	98.60
IUUC-Xtr-132043	Xenopus tropicalis	59.69	0.00e+00	790.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence