iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000022750.17	ENSMUST00000117192.7	ENSMUSP00000114115.1
ENSMUSG00000022750.17	ENSMUST00000120488.2	ENSMUSP00000112412.1

Annotation

mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
miRTarBase	microRNA	TRANSFAC	RepTar
RAID2
Post-translational Modifications (PTMs)
CPLM
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.50e-19	70.1	51	115
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	8.70e-07	28.3	150	179

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+lvv+g++++ah+i Laas+++F+ +f ++l+e++ +++v i++v++ ++ ++l+F+Yt++l++
   Q: 51   DVVLVVEGKHIEAHRILLAASCDYFRGMFAGGLKEME-QEEVLIHGVSYNAMCQILHFIYTSELEL 115
           9***********************************8.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhF 31
           eN l+++r+Adl+d+ +L ++ +++ilk+F
   Q: 150  ENILDVYRLADLFDLNHLTQQLDTYILKNF 179
           8***************************** PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MAEEQDFAQL CRLPTQPSHS HCVNNTYRST QHSQALLRGL LALRDSGILF DVVLVVEGKH 60
IEAHRILLAA SCDYFRGMFA GGLKEMEQEE VLIHGVSYNA MCQILHFIYT SELELSLSNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGAGGCTC CGCCCCCACC TCCAGCCTCC CGCCTCCCGC CTGCTGCGAG AGCGGCCTCA 60
GCTTGCGGCA GCACCAGGTC AGCTGCGAGG CATGTACCGT GCGGGCCCGG CAGGCCTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030575--KLHL22
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0051301--P:cell division
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002097	Ailuropoda melanoleuca	93.78	0.00e+00	1182.00
IUUC-Apl-004081	Anas platyrhynchos	77.02	0.00e+00	1004.00
IUUC-Aca-005015	Anolis carolinensis	66.50	0.00e+00	846.00
IUUC-Ame-011712	Astyanax mexicanus	58.80	0.00e+00	718.00
IUUC-Bta-012594	Bos taurus	91.71	0.00e+00	1181.00
IUUC-Cja-019752	Callithrix jacchus	93.98	0.00e+00	984.00
IUUC-Cfa-020884	Canis familiaris	94.26	0.00e+00	1219.00
IUUC-Cpo-021711	Cavia porcellus	93.62	0.00e+00	1214.00
IUUC-Csa-023211	Chlorocebus sabaeus	94.42	0.00e+00	1216.00
IUUC-Dre-028395	Danio rerio	62.11	0.00e+00	748.00
IUUC-Dno-030096	Dasypus novemcinctus	91.44	0.00e+00	1180.00
IUUC-Dor-030709	Dipodomys ordii	94.32	0.00e+00	697.00
IUUC-Eca-033388	Equus caballus	94.42	0.00e+00	1218.00
IUUC-Eeu-034616	Erinaceus europaeus	82.14	0.00e+00	1044.00
IUUC-Fca-035815	Felis catus	94.10	0.00e+00	1217.00
IUUC-Fal-037311	Ficedula albicollis	79.61	0.00e+00	989.00
IUUC-Gmo-039571	Gadus morhua	52.08	2.00e-157	548.00
IUUC-Gga-040992	Gallus gallus	76.86	0.00e+00	1004.00
IUUC-Gac-042041	Gasterosteus aculeatus	57.65	0.00e+00	681.00
IUUC-Ggo-045141	Gorilla gorilla	88.68	0.00e+00	1140.00
IUUC-Hsa-045984	Homo sapiens	94.58	0.00e+00	1219.00
IUUC-Itr-048890	Ictidomys tridecemlineatus	95.06	0.00e+00	1230.00
IUUC-Lch-049700	Latimeria chalumnae	61.73	0.00e+00	729.00
IUUC-Loc-052141	Lepisosteus oculatus	61.34	0.00e+00	802.00
IUUC-Laf-053487	Loxodonta africana	91.97	0.00e+00	1172.00
IUUC-Mcc-054682	Macaca mulatta	94.55	0.00e+00	994.00
IUUC-Meu-055937	Macropus eugenii	72.90	0.00e+00	940.00
IUUC-Mga-059953	Meleagris gallopavo	76.86	0.00e+00	1004.00
IUUC-Mmr-061743	Microcebus murinus	93.94	0.00e+00	1210.00
IUUC-Mdo-062328	Monodelphis domestica	81.30	0.00e+00	1059.00
IUUC-Mpu-066750	Mustela putorius furo	94.42	0.00e+00	1219.00
IUUC-Mlu-066960	Myotis lucifugus	92.50	0.00e+00	1189.00
IUUC-Nle-069690	Nomascus leucogenys	95.09	0.00e+00	1095.00
IUUC-Opr-071059	Ochotona princeps	87.26	0.00e+00	1102.00
IUUC-Ont-072004	Oreochromis niloticus	57.80	0.00e+00	681.00
IUUC-Oan-073172	Ornithorhynchus anatinus	62.58	0.00e+00	728.00
IUUC-Ocu-074310	Oryctolagus cuniculus	92.22	8.00e-145	505.00
IUUC-Ola-086599	Oryzias latipes	55.54	0.00e+00	694.00
IUUC-Oga-087980	Otolemur garnettii	93.78	0.00e+00	1207.00
IUUC-Oar-089956	Ovis aries	77.32	0.00e+00	892.00
IUUC-Ptr-090598	Pan troglodytes	95.29	0.00e+00	1101.00
IUUC-Pan-092387	Papio anubis	94.36	0.00e+00	994.00
IUUC-Psi-093484	Pelodiscus sinensis	77.81	0.00e+00	1028.00
IUUC-Pma-094224	Petromyzon marinus	49.51	6.00e-171	593.00
IUUC-Pfo-096149	Poecilia formosa	59.09	0.00e+00	718.00
IUUC-Pab-098097	Pongo abelii	94.42	0.00e+00	1219.00
IUUC-Pca-100118	Procavia capensis	93.24	0.00e+00	688.00
IUUC-Pva-103174	Pteropus vampyrus	91.41	2.00e-144	506.00
IUUC-Rno-105350	Rattus norvegicus	98.05	0.00e+00	1262.00
IUUC-Sha-106817	Sarcophilus harrisii	81.15	5.00e-128	451.00
IUUC-Sar-113490	Sorex araneus	93.88	0.00e+00	636.00
IUUC-Ssc-115827	Sus scrofa	93.30	0.00e+00	1205.00
IUUC-Tgu-116748	Taeniopygia guttata	82.32	0.00e+00	902.00
IUUC-Tru-118644	Takifugu rubripes	57.67	0.00e+00	691.00
IUUC-Tsy-118888	Tarsius syrichta	87.84	0.00e+00	994.00
IUUC-Tni-120060	Tetraodon nigroviridis	54.28	1.00e-175	609.00
IUUC-Ttr-129183	Tursiops truncatus	93.10	0.00e+00	1078.00
IUUC-Xtr-132780	Xenopus tropicalis	69.38	0.00e+00	886.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence