iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003543

Ensembl Protein ID

ENSAPLP00000013925.1

UniProt Accession

U3J348; U3J348_ANAPL

Genbank Protein ID

ENSAPLP00000013925

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01054881

Gene Name

KLHL25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000014114.1	ENSAPLT00000014692.1	ENSAPLP00000013925.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	5.00e-19	68.2	46	114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	4.50e-08	32.4	146	177

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgkldene 69
           +Dv+l  g++ f++h++vLaasS++F+a+f+++l+es   + v+++d + pev++ ll+F Y++++ +ne
   Q: 46   TDVTLWAGNRSFPCHRAVLAASSRYFEAMFSNGLRESL-DDAVNFHDsLHPEVLELLLDFAYSSRIIINE 114
           7************************************9.*******99*****************99987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclg++ ++d+++c++L++   +++l +F+
   Q: 146  PSNCLGMMLLSDAHQCRRLYELSWRMCLVNFE 177
           89****************************95 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

MSVSVHENRK SRTSTGSMNI LLFHKASHPD CVLSHLNTLR KHCMFTDVTL WAGNRSFPCH 60
RAVLAASSRY FEAMFSNGLR ESLDDAVNFH DSLHPEVLEL LLDFAYSSRI IINEENAESL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAGTCA GCGTCCACGA GAACCGTAAA TCCCGGACGA GCACCGGCTC CATGAACATC 60
TTGCTCTTCC ACAAAGCTTC CCACCCGGAC TGTGTGCTGT CCCACCTGAA CACCCTGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030565--KLHL25
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0006446--P:regulation of translational initiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002373	Ailuropoda melanoleuca	90.51	0.00e+00	1133.00
IUUC-Aca-004729	Anolis carolinensis	91.69	0.00e+00	1120.00
IUUC-Ame-011020	Astyanax mexicanus	86.95	0.00e+00	1052.00
IUUC-Bta-012955	Bos taurus	88.81	0.00e+00	1115.00
IUUC-Cja-018839	Callithrix jacchus	89.83	0.00e+00	1125.00
IUUC-Cfa-020224	Canis familiaris	90.68	0.00e+00	1134.00
IUUC-Cpo-021593	Cavia porcellus	86.95	0.00e+00	1048.00
IUUC-Csa-023276	Chlorocebus sabaeus	90.51	0.00e+00	1133.00
IUUC-Dre-028053	Danio rerio	86.78	0.00e+00	1026.00
IUUC-Dno-029287	Dasypus novemcinctus	88.31	0.00e+00	1107.00
IUUC-Dor-030908	Dipodomys ordii	82.20	0.00e+00	1003.00
IUUC-Fca-035897	Felis catus	90.34	0.00e+00	1130.00
IUUC-Fal-037036	Ficedula albicollis	98.81	0.00e+00	1181.00
IUUC-Gmo-039345	Gadus morhua	84.92	0.00e+00	1002.00
IUUC-Gga-040404	Gallus gallus	98.47	0.00e+00	1179.00
IUUC-Gac-042447	Gasterosteus aculeatus	85.08	0.00e+00	1015.00
IUUC-Ggo-045060	Gorilla gorilla	90.34	0.00e+00	1132.00
IUUC-Hsa-046494	Homo sapiens	90.34	0.00e+00	1132.00
IUUC-Itr-047993	Ictidomys tridecemlineatus	90.85	0.00e+00	1132.00
IUUC-Lch-050211	Latimeria chalumnae	87.97	0.00e+00	1068.00
IUUC-Loc-052578	Lepisosteus oculatus	85.76	0.00e+00	1050.00
IUUC-Laf-053498	Loxodonta africana	90.68	0.00e+00	1082.00
IUUC-Mcc-055033	Macaca mulatta	90.51	0.00e+00	1133.00
IUUC-Meu-056893	Macropus eugenii	92.88	0.00e+00	1154.00
IUUC-Mga-060025	Meleagris gallopavo	98.81	0.00e+00	1182.00
IUUC-Mmr-060658	Microcebus murinus	89.49	0.00e+00	1123.00
IUUC-Mdo-062667	Monodelphis domestica	93.22	0.00e+00	1154.00
IUUC-Mmu-063125	Mus musculus	88.31	0.00e+00	1068.00
IUUC-Mpu-066209	Mustela putorius furo	90.51	0.00e+00	1134.00
IUUC-Mlu-068237	Myotis lucifugus	87.97	0.00e+00	1076.00
IUUC-Nle-069454	Nomascus leucogenys	90.41	0.00e+00	1118.00
IUUC-Ont-072138	Oreochromis niloticus	85.59	0.00e+00	1009.00
IUUC-Oan-073320	Ornithorhynchus anatinus	84.75	0.00e+00	1058.00
IUUC-Ocu-073765	Oryctolagus cuniculus	85.59	0.00e+00	1048.00
IUUC-Oga-088002	Otolemur garnettii	89.32	0.00e+00	1113.00
IUUC-Oar-089481	Ovis aries	88.47	0.00e+00	1113.00
IUUC-Ptr-091200	Pan troglodytes	90.17	0.00e+00	1127.00
IUUC-Psi-093884	Pelodiscus sinensis	95.08	0.00e+00	1149.00
IUUC-Pno-095143	Phaeosphaeria nodorum	27.31	6.00e-15	74.70
IUUC-Pva-102321	Pteropus vampyrus	89.32	0.00e+00	1117.00
IUUC-Rno-104835	Rattus norvegicus	87.63	0.00e+00	1064.00
IUUC-Sha-107528	Sarcophilus harrisii	93.05	0.00e+00	1155.00
IUUC-Ssc-116161	Sus scrofa	90.00	0.00e+00	1126.00
IUUC-Tgu-116569	Taeniopygia guttata	98.64	0.00e+00	1177.00
IUUC-Tni-120525	Tetraodon nigroviridis	76.52	0.00e+00	888.00
IUUC-Ttr-129297	Tursiops truncatus	89.49	0.00e+00	1121.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence