iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037534

Ensembl Protein ID

ENSFALP00000010501.1

UniProt Accession

U3K647; U3K647_FICAL

Genbank Protein ID

ENSFALP00000010501

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01000611

Gene Name

KIF21A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000010069.1	ENSFALT00000010543.1	ENSFALP00000010501.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.00e-30	101.3	1328	1362
UBD/Beta-Prp	1.90e-44	151.7	1433	1640

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           gHt  v c++ +d+ll +Gs D t+kvW+l tg  
   Q: 1328 GHTKAVLCVDATDDLLFTGSKDRTCKVWNLVTGQE 1362
           8********9878*****************99976 PP

UBD/Beta-Prp

   S: 51   heaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sg.dklvsGshdrtirvwdletgqclee... 131
            e++++++ ++p+g +++ ++  ++++ wdl+ ++ + +l+gh+  v++l++++  +g d +v+Gs+d +i+++d+ +g   +    
   Q: 1433 GENQINQIALNPTG-TFLYAAAGNAVRMWDLKRFQSTGKLTGHQGPVMCLTVDQisNGqDLIVTGSKDHYIKMFDVTEGALGSVspt 1518
           57789********9.9***************************************9888*******************987766777 PP
   S: 132  ..tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvr 216
             ++ +h + +  +++++  + l+sGs D+ ++ Wdl++++ll++   +h+d v  l + +  + l+sg + gt+klw++ t   + 
   Q: 1519 hnFEPPHYDGIEALAIMG--DNLFSGSRDNGIKKWDLSQKDLLQQVPNAHKDWVCALGLVPGAPVLLSGCRGGTLKLWNVDTFAPIG 1603
           889999************..6799**********************999************************************** PP
   S: 217  tlnghtdnvksvrfspnderlvsgssDgsiriW...dlr 252
           +++gh+++++ + +   +  + ++++D+++riW   ++ 
   Q: 1604 EMKGHDSPINAICTN--SSQIFTAADDRTVRIWkarNVM 1640
           **********87777..****************555544 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MSAGPDESSV RVAVRIRPQL AKEKIEGCHI CTSVTPGEPQ VFLGKDKAFT FDYVFNIDSQ 60
QEEIYVQCIE KLIEGCFEGY NATVFAYGQT GAGKTYTMGT GFDVNITEEE QGIISRAVKH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCAGCTCC CGGCGGGGCC GCGGCCGCCC CTCGCCCGCC GCACCATGTC GGCCGGCCCG 60
GACGAGAGCT CGGTGCGGGT GGCGGTCAGG TAAGCGGGGC TCCTGCGGGC CGTGTTCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001391	Ailuropoda melanoleuca	85.15	0.00e+00	2719.00
IUUC-Apl-003353	Anas platyrhynchos	91.45	0.00e+00	2844.00
IUUC-Aca-004467	Anolis carolinensis	86.45	0.00e+00	2779.00
IUUC-Bta-013485	Bos taurus	83.91	0.00e+00	2634.00
IUUC-Cel-018402	Caenorhabditis elegans	52.61	1.00e-150	527.00
IUUC-Cja-019385	Callithrix jacchus	83.00	0.00e+00	2620.00
IUUC-Cfa-020986	Canis familiaris	84.67	0.00e+00	2663.00
IUUC-Cpo-022297	Cavia porcellus	82.80	0.00e+00	1586.00
IUUC-Csa-023685	Chlorocebus sabaeus	84.05	0.00e+00	2683.00
IUUC-Cho-024531	Choloepus hoffmanni	84.64	0.00e+00	984.00
IUUC-Csv-026158	Ciona savignyi	58.40	4.00e-177	615.00
IUUC-Dre-028532	Danio rerio	64.56	0.00e+00	1278.00
IUUC-Dno-029972	Dasypus novemcinctus	81.33	0.00e+00	2526.00
IUUC-Ete-032872	Echinops telfairi	70.69	0.00e+00	910.00
IUUC-Eca-033518	Equus caballus	84.28	0.00e+00	2677.00
IUUC-Fca-036197	Felis catus	84.30	0.00e+00	2667.00
IUUC-Gga-040687	Gallus gallus	90.89	0.00e+00	2811.00
IUUC-Gac-041626	Gasterosteus aculeatus	67.43	0.00e+00	2138.00
IUUC-Ggo-044457	Gorilla gorilla	84.59	0.00e+00	2660.00
IUUC-Hsa-046372	Homo sapiens	84.80	0.00e+00	2685.00
IUUC-Loc-052689	Lepisosteus oculatus	74.69	0.00e+00	2360.00
IUUC-Laf-054018	Loxodonta africana	81.41	0.00e+00	2501.00
IUUC-Mcc-055558	Macaca mulatta	84.98	0.00e+00	2695.00
IUUC-Meu-056080	Macropus eugenii	83.73	0.00e+00	932.00
IUUC-Mga-059283	Meleagris gallopavo	91.63	0.00e+00	2764.00
IUUC-Mmr-060773	Microcebus murinus	83.86	0.00e+00	2603.00
IUUC-Mdo-062688	Monodelphis domestica	83.31	0.00e+00	2421.00
IUUC-Mmu-063997	Mus musculus	84.06	0.00e+00	1613.00
IUUC-Mpu-066354	Mustela putorius furo	85.83	0.00e+00	2691.00
IUUC-Mlu-067599	Myotis lucifugus	83.79	0.00e+00	2639.00
IUUC-Nle-069477	Nomascus leucogenys	84.92	0.00e+00	2692.00
IUUC-Opr-070188	Ochotona princeps	81.27	0.00e+00	1237.00
IUUC-Oan-073055	Ornithorhynchus anatinus	83.09	0.00e+00	2492.00
IUUC-Ocu-074302	Oryctolagus cuniculus	81.59	0.00e+00	2633.00
IUUC-Ola-086604	Oryzias latipes	66.53	0.00e+00	2086.00
IUUC-Oga-088799	Otolemur garnettii	83.12	0.00e+00	2371.00
IUUC-Oar-089629	Ovis aries	85.01	0.00e+00	2638.00
IUUC-Pan-092214	Papio anubis	85.89	0.00e+00	2694.00
IUUC-Psi-093757	Pelodiscus sinensis	84.62	0.00e+00	2572.00
IUUC-Pfo-097448	Poecilia formosa	63.55	0.00e+00	1912.00
IUUC-Pab-097984	Pongo abelii	84.80	0.00e+00	2677.00
IUUC-Pca-101061	Procavia capensis	72.43	0.00e+00	1265.00
IUUC-Pva-102306	Pteropus vampyrus	85.10	0.00e+00	2603.00
IUUC-Rno-105354	Rattus norvegicus	83.48	0.00e+00	1605.00
IUUC-Sha-106938	Sarcophilus harrisii	83.46	0.00e+00	1665.00
IUUC-Ssc-115810	Sus scrofa	83.70	0.00e+00	2630.00
IUUC-Tgu-117076	Taeniopygia guttata	96.02	0.00e+00	2833.00
IUUC-Tsy-119020	Tarsius syrichta	85.45	0.00e+00	2659.00
IUUC-Tni-120813	Tetraodon nigroviridis	63.88	0.00e+00	1217.00
IUUC-Tbe-127494	Tupaia belangeri	71.60	0.00e+00	880.00
IUUC-Ttr-128393	Tursiops truncatus	80.02	0.00e+00	2433.00
IUUC-Vpa-130675	Vicugna pacos	92.13	0.00e+00	685.00
IUUC-Vvi-130947	Vitis vinifera	30.36	5.00e-16	79.70
IUUC-Xtr-132829	Xenopus tropicalis	77.81	0.00e+00	2483.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence