iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010903

Ensembl Protein ID

ENSAMXP00000002558.1

UniProt Accession

W5K4P7; W5K4P7_ASTMX

Genbank Protein ID

ENSAMXP00000002558

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01078023

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000002501.1	ENSAMXT00000002558.1	ENSAMXP00000002558.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-68	232.2	220	533

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +GlkN+g+tCYmNS+LQ+L+++++lr+++    + +      +++++++  +lq++f el ++++k v +++l+k++++e   +++++q
   Q: 220  VGLKNQGATCYMNSLLQTLFFTNQLRRAVYM-MPTEG-----DDSSKSVPLALQRVFYEL-QHSDKPVGTKKLTKSFGWET--LDSFMQ 299
           6******************************.44433.....466889************.88889************887..67**** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +D+qE++++lld++e+++                          k +  + +i +lF+g++ s i+c++ d +s+r e+ +d++l+++g
   Q: 300  HDVQELCRVLLDNVENKM--------------------------KGTCVEGTIPKLFRGKMVSYIQCKHVDYRSERIEDYYDIQLSIKG 362
           ******************..........................789****************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
           k+     ++ ++++++++ e+l+g+nky   +  ++qeaek +k+ ++P++L+l+L+Rf ++ ++++++kin+++efp++L l++f+++
   Q: 363  KK-----NIFESFKDYVAVEQLDGDNKYDAGEH-GLQEAEKGVKFLTFPPILHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQK 445
           **.....9*********************9996.7****************************************************** PP
   S: 268  peekqkekkkYeLiavvvHsGslssGHYvayvknekgk........WllfdDskVtevkeeevleetg............staYvlfYk 336
           p+ k+  + +Y L+av+vHsG  ++GHYv+y + + ++        W++fdD+ V+ +++ee  e +             ++aY+l+Y 
   Q: 446  PDVKD--PANYILHAVLVHSGDNHGGHYVVYLNPKGDGkvsvtepiWCKFDDDVVSRCTKEEAIEHNYgghdddlsvrhcTNAYMLVYI 532
           99888..*************************99544468888899************86666664446*******************8 PP
   S: 337  r 337
           r
   Q: 533  R 533
           7 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MNHHHHTQQQ QQQQQQKAGE QQLSEPEDME MEAGDTDDPP RIPPNPVING NVAMADGHNN 60
TEEDMEDDTS WRSEATFRFV VERFSRLSES VLSPSCFVRN LPWKIMVMPR FYPDRPHQKS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAACCACC ACCACCACAC TCAACAACAA CAGCAGCAGC AGCAACAGAA AGCCGGCGAG 60
CAGCAGCTCA GCGAGCCGGA GGACATGGAG ATGGAAGGTA GCTAGCTGCA GCGTGTGTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR002083--MATH/TRAF_dom
IPR001394--Peptidase_C19_UCH
IPR008974--TRAF-like
IPR024729--USP7_ICP0-binding_dom
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50144--MATH
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00917--MATH
PF00443--UCH
PF14533--USP7_C2
PF12436--USP7_ICP0_bdg

SMART

SM00061--MATH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000761	Aegilops tauschii	32.66	8.00e-139	488.00
IUUC-Aml-002408	Ailuropoda melanoleuca	93.63	0.00e+00	2107.00
IUUC-Atr-003067	Amborella trichopoda	37.12	4.00e-120	426.00
IUUC-Apl-003558	Anas platyrhynchos	93.92	0.00e+00	2136.00
IUUC-Aca-004518	Anolis carolinensis	88.37	0.00e+00	1996.00
IUUC-Aly-006427	Arabidopsis lyrata	35.41	3.00e-152	533.00
IUUC-Ath-006591	Arabidopsis thaliana	35.35	3.00e-152	532.00
IUUC-Ago-007849	Ashbya gossypii	32.09	1.00e-138	488.00
IUUC-Acl-008327	Aspergillus clavatus	34.35	5.00e-173	602.00
IUUC-Afl-008491	Aspergillus flavus	34.62	7.00e-166	578.00
IUUC-Afu-008804	Aspergillus fumigatus	35.18	7.00e-164	571.00
IUUC-Ang-009776	Aspergillus niger	34.83	2.00e-163	570.00
IUUC-Aor-009998	Aspergillus oryzae	33.89	1.00e-157	550.00
IUUC-Ate-010428	Aspergillus terreus	35.02	1.00e-167	584.00
IUUC-Bgr-012132	Blumeria graminis	31.32	5.00e-144	505.00
IUUC-Bta-013192	Bos taurus	93.10	0.00e+00	2101.00
IUUC-Bci-013924	Botrytis cinerea	34.48	8.00e-153	534.00
IUUC-Bdi-014920	Brachypodium distachyon	35.26	1.00e-153	537.00
IUUC-Bol-015224	Brassica oleracea	36.16	3.00e-152	532.00
IUUC-Bra-017448	Brassica rapa	36.04	2.00e-151	530.00
IUUC-Cel-018219	Caenorhabditis elegans	33.98	3.00e-154	539.00
IUUC-Cja-019006	Callithrix jacchus	92.45	0.00e+00	2075.00
IUUC-Cfa-020361	Canis familiaris	92.81	0.00e+00	2108.00
IUUC-Cpo-022320	Cavia porcellus	93.18	0.00e+00	2098.00
IUUC-Cre-022708	Chlamydomonas reinhardtii	41.37	2.00e-90	325.00
IUUC-Csa-024050	Chlorocebus sabaeus	93.63	0.00e+00	2134.00
IUUC-Cho-024434	Choloepus hoffmanni	84.68	0.00e+00	1347.00
IUUC-Cin-025689	Ciona intestinalis	53.65	0.00e+00	1204.00
IUUC-Csv-025963	Ciona savignyi	52.88	0.00e+00	1157.00
IUUC-Cgl-026650	Colletotrichum gloeosporioides	33.21	1.00e-149	524.00
IUUC-Cne-026968	Cryptococcus neoformans	36.51	5.00e-180	625.00
IUUC-Cme-027103	Cyanidioschyzon merolae	35.98	5.00e-117	416.00
IUUC-Dre-028510	Danio rerio	98.21	0.00e+00	2265.00
IUUC-Dno-029696	Dasypus novemcinctus	93.27	0.00e+00	2094.00
IUUC-Dor-030611	Dipodomys ordii	86.18	0.00e+00	690.00
IUUC-Dse-031433	Dothistroma septosporum	34.77	2.00e-149	523.00
IUUC-Dme-031583	Drosophila melanogaster	48.08	0.00e+00	1031.00
IUUC-Ete-033191	Echinops telfairi	92.16	0.00e+00	2068.00
IUUC-Eca-034122	Equus caballus	93.36	0.00e+00	2103.00
IUUC-Eeu-035292	Erinaceus europaeus	80.43	0.00e+00	656.00
IUUC-Fca-036377	Felis catus	93.63	0.00e+00	2106.00
IUUC-Fal-036964	Ficedula albicollis	94.16	0.00e+00	2100.00
IUUC-Fox-037695	Fusarium oxysporum	32.71	3.00e-160	559.00
IUUC-Fso-038084	Fusarium solani	33.63	1.00e-159	557.00
IUUC-Gmo-038644	Gadus morhua	97.00	0.00e+00	2231.00
IUUC-Ggr-040029	Gaeumannomyces graminis	33.54	2.00e-158	553.00
IUUC-Gga-040944	Gallus gallus	94.09	0.00e+00	2133.00
IUUC-Gac-041740	Gasterosteus aculeatus	96.23	0.00e+00	2237.00
IUUC-Gma-043300	Glycine max	36.12	2.00e-164	573.00
IUUC-Ggo-044947	Gorilla gorilla	93.19	0.00e+00	2105.00
IUUC-Hsa-046278	Homo sapiens	93.45	0.00e+00	2132.00
IUUC-Hvu-047749	Hordeum vulgare	36.29	3.00e-136	479.00
IUUC-Itr-047904	Ictidomys tridecemlineatus	93.40	0.00e+00	1810.00
IUUC-Kpa-049121	Komagataella pastoris	30.79	4.00e-132	466.00
IUUC-Lch-049847	Latimeria chalumnae	94.88	0.00e+00	2180.00
IUUC-Lpe-051505	Leersia perrieri	35.52	9.00e-140	491.00
IUUC-Loc-052234	Lepisosteus oculatus	96.53	0.00e+00	1517.00
IUUC-Lma-053169	Leptosphaeria maculans	36.47	1.00e-169	590.00
IUUC-Laf-053566	Loxodonta africana	93.46	0.00e+00	2105.00
IUUC-Mcc-055549	Macaca mulatta	92.94	0.00e+00	2102.00
IUUC-Meu-056887	Macropus eugenii	83.93	0.00e+00	1219.00
IUUC-Mor-057149	Magnaporthe oryzae	34.32	3.00e-160	559.00
IUUC-Mpo-057536	Magnaporthe poae	33.42	2.00e-158	553.00
IUUC-Mtr-058583	Medicago truncatula	37.14	7.00e-157	548.00
IUUC-Mla-058899	Melampsora laricipopulina	36.37	2.00e-168	587.00
IUUC-Mga-060148	Meleagris gallopavo	94.09	0.00e+00	2140.00
IUUC-Mvi-060207	Microbotryum violaceum	36.40	0.00e+00	628.00
IUUC-Mmr-060946	Microcebus murinus	93.35	0.00e+00	2127.00
IUUC-Mdo-062079	Monodelphis domestica	86.96	0.00e+00	1902.00
IUUC-Mmu-063678	Mus musculus	92.84	0.00e+00	2096.00
IUUC-Mac-065416	Musa acuminata	36.77	6.00e-151	528.00
IUUC-Mpu-066744	Mustela putorius furo	93.50	0.00e+00	2063.00
IUUC-Mlu-067949	Myotis lucifugus	92.08	0.00e+00	2083.00
IUUC-Nfi-068342	Neosartorya fischeri	35.00	6.00e-164	572.00
IUUC-Ncr-068818	Neurospora crassa	34.12	3.00e-161	563.00
IUUC-Nle-070064	Nomascus leucogenys	93.54	0.00e+00	2132.00
IUUC-Opr-071001	Ochotona princeps	92.08	0.00e+00	1741.00
IUUC-Ont-072095	Oreochromis niloticus	97.85	0.00e+00	2273.00
IUUC-Oan-073483	Ornithorhynchus anatinus	94.35	0.00e+00	2073.00
IUUC-Ocu-073967	Oryctolagus cuniculus	92.59	0.00e+00	2018.00
IUUC-Oba-075811	Oryza barthii	33.99	1.00e-138	487.00
IUUC-Obr-076514	Oryza brachyantha	36.33	2.00e-151	530.00
IUUC-Ogl-077038	Oryza glaberrima	35.38	2.00e-147	516.00
IUUC-Ogu-078265	Oryza glumaepatula	33.88	1.00e-133	471.00
IUUC-Oin-079513	Oryza indica	35.69	4.00e-138	486.00
IUUC-Olo-081067	Oryza longistaminata	34.68	4.00e-137	482.00
IUUC-Ome-081879	Oryza meridionalis	35.94	8.00e-147	514.00
IUUC-Oni-082461	Oryza nivara	34.73	2.00e-144	506.00
IUUC-Opu-083199	Oryza punctata	35.36	2.00e-143	503.00
IUUC-Oru-085109	Oryza rufipogon	35.43	4.00e-142	499.00
IUUC-Osa-085418	Oryza sativa	38.78	4.00e-129	456.00
IUUC-Ola-086640	Oryzias latipes	95.96	0.00e+00	2226.00
IUUC-Olu-087874	Ostreococcus lucimarinus	32.87	4.00e-142	499.00
IUUC-Oga-089059	Otolemur garnettii	86.72	0.00e+00	1915.00
IUUC-Oar-089710	Ovis aries	93.36	0.00e+00	2102.00
IUUC-Ptr-091334	Pan troglodytes	93.19	0.00e+00	2105.00
IUUC-Pan-091717	Papio anubis	93.72	0.00e+00	2041.00
IUUC-Psi-093933	Pelodiscus sinensis	93.75	0.00e+00	2164.00
IUUC-Pma-094648	Petromyzon marinus	83.01	0.00e+00	1727.00
IUUC-Pno-095020	Phaeosphaeria nodorum	35.83	8.00e-156	544.00
IUUC-Ppa-095922	Physcomitrella patens	35.94	2.00e-155	543.00
IUUC-Pfo-096181	Poecilia formosa	96.95	0.00e+00	2244.00
IUUC-Pab-098231	Pongo abelii	90.71	0.00e+00	2034.00
IUUC-Pop-099680	Populus trichocarpa	36.63	6.00e-156	545.00
IUUC-Pca-100543	Procavia capensis	77.58	0.00e+00	974.00
IUUC-Ppe-101523	Prunus persica	36.00	2.00e-150	526.00
IUUC-Pva-102472	Pteropus vampyrus	91.53	0.00e+00	2056.00
IUUC-Pgr-103463	Puccinia graminis	35.89	2.00e-170	593.00
IUUC-Ptt-103716	Puccinia triticina	37.81	2.00e-166	580.00
IUUC-Pte-104360	Pyrenophora teres	37.29	2.00e-155	543.00
IUUC-Pyt-104581	Pyrenophora triticirepentis	37.20	4.00e-155	542.00
IUUC-Rno-105816	Rattus norvegicus	93.27	0.00e+00	2128.00
IUUC-Sce-106230	Saccharomyces cerevisiae	39.29	4.00e-117	416.00
IUUC-Sha-107439	Sarcophilus harrisii	94.18	0.00e+00	2109.00
IUUC-Sja-107690	Schizosaccharomyces japonicus	31.96	1.00e-135	478.00
IUUC-Spo-108019	Schizosaccharomyces pombe	34.35	1.00e-142	501.00
IUUC-Smo-109308	Selaginella moellendorffii	35.92	5.00e-151	528.00
IUUC-Sit-110367	Setaria italica	35.75	5.00e-154	538.00
IUUC-Sly-111337	Solanum lycopersicum	36.92	2.00e-158	553.00
IUUC-Stu-112387	Solanum tuberosum	36.36	1.00e-159	557.00
IUUC-Sar-113685	Sorex araneus	92.53	0.00e+00	2078.00
IUUC-Sbi-114037	Sorghum bicolor	36.72	2.00e-153	536.00
IUUC-Sre-115156	Sporisorium reilianum	37.88	0.00e+00	637.00
IUUC-Ssc-116297	Sus scrofa	93.63	0.00e+00	2134.00
IUUC-Tgu-116767	Taeniopygia guttata	93.91	0.00e+00	2163.00
IUUC-Tru-118208	Takifugu rubripes	96.54	0.00e+00	2204.00
IUUC-Tsy-119277	Tarsius syrichta	84.54	0.00e+00	687.00
IUUC-Tni-119890	Tetraodon nigroviridis	96.36	0.00e+00	2199.00
IUUC-Tca-121501	Theobroma cacao	35.82	3.00e-155	542.00
IUUC-Tre-122169	Trichoderma reesei	33.09	8.00e-152	531.00
IUUC-Tvi-122600	Trichoderma virens	33.91	2.00e-160	560.00
IUUC-Tae-125264	Triticum aestivum	35.25	4.00e-150	526.00
IUUC-Tur-126287	Triticum urartu	35.12	4.00e-146	512.00
IUUC-Tme-127045	Tuber melanosporum	35.35	9.00e-171	594.00
IUUC-Tbe-127696	Tupaia belangeri	84.36	7.00e-152	531.00
IUUC-Ttr-129161	Tursiops truncatus	93.54	0.00e+00	2099.00
IUUC-Uma-129535	Ustilago maydis	37.67	0.00e+00	658.00
IUUC-Vda-129708	Verticillium dahliae	32.75	6.00e-157	548.00
IUUC-Vvi-131048	Vitis vinifera	35.84	8.00e-155	541.00
IUUC-Xtr-132073	Xenopus tropicalis	90.15	0.00e+00	2063.00
IUUC-Xma-133949	Xiphophorus maculatus	96.77	0.00e+00	2236.00
IUUC-Yli-134527	Yarrowia lipolytica	32.81	3.00e-134	473.00
IUUC-Zma-135855	Zea mays	36.25	4.00e-145	509.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence