iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093044

Ensembl Protein ID

ENSPSIP00000010991.1

UniProt Accession

K7FSI1; K7FSI1_PELSI

Genbank Protein ID

ENSPSIP00000010991

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01014358

Gene Name

COPA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000009617.1	ENSPSIT00000011047.1	ENSPSIP00000010991.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.90e-34	114.3	49	79
UBD/Beta-Prp	1.80e-72	244.0	14	306

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDl 30
           H ++v++++f  + +l+vsG+dD +ikvW++
   Q: 49   HDGPVRGIDFhkQQPLFVSGGDDYKIKVWNY 79
           99********97449**************96 PP

UBD/Beta-Prp

   S: 16   vkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp 104
           + f+p++++++t+  +g i++wd+++ +l+ ++ +h+++v+ ++f+++++++v+g++D+ ikvw+++ + c+ tl gh d+++++ f+ 
   Q: 14   LSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHH 102
           679************************************************************************************** PP
   S: 105  sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl........................... 166
           +  +++s+s+d+tirvw++++++c+  +l+gh++ v+c ++hp+++l+vs+slD+tvr+Wd+                           
   Q: 103  EYPWILSASDDQTIRVWNWQSRTCVC-VLTGHNHYVMCSQFHPSEDLVVSASLDQTVRVWDIsglrkknlspgavesdvrgitgvdlfg 190
           **************************.************************************************************** PP
   S: 167  ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrs 253
            t+ ++++  +gh++ v++ +f+++++ +vsg++d++vk+w + +++   v+t++gh +nv++  f+p++e+++s s+D+sir+Wd+ +
   Q: 191  TTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAweVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSK 279
           888888888777********************************888888*************************************** PP
   S: 254  gdllktlqlhnssvisvavlsfgdnvlv 281
           ++ ++t+ + +++++  a+ +++ n ++
   Q: 280  RTGVQTFRRDHDRFWVLAA-HPNLNLFA 306
           ****************999.66655554 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

LTESFITLHL SLGLSFHPKR PWILTSLHNG VIQLWDYRMC TLIDKFDEHD GPVRGIDFHK 60
QQPLFVSGGD DYKIKVWNYK LRRCLFTLLG HLDYIRTTFF HHEYPWILSA SDDQTIRVWN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTAACTGAAA GCTTCATTAC TTTGCATCTC TCTTTAGGGC TCAGCTTTCA CCCTAAGCGG 60
CCCTGGATCC TCACGAGTTT GCACAACGGA GTGATCCAGC TATGGGACTA CCGGATGTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0070062--C:extracellular exosome
GO:0005615--C:extracellular space
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0030157--P:pancreatic juice secretion
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000064	Aegilops tauschii	54.25	0.00e+00	894.00
IUUC-Aml-001758	Ailuropoda melanoleuca	79.30	0.00e+00	1691.00
IUUC-Atr-002493	Amborella trichopoda	47.96	0.00e+00	942.00
IUUC-Apl-003385	Anas platyrhynchos	76.42	0.00e+00	1377.00
IUUC-Aca-005154	Anolis carolinensis	96.39	3.00e-113	400.00
IUUC-Aly-006020	Arabidopsis lyrata	53.27	0.00e+00	868.00
IUUC-Ath-007058	Arabidopsis thaliana	47.77	0.00e+00	941.00
IUUC-Ago-007992	Ashbya gossypii	41.40	0.00e+00	798.00
IUUC-Acl-008027	Aspergillus clavatus	51.09	0.00e+00	838.00
IUUC-Afl-008644	Aspergillus flavus	51.27	0.00e+00	836.00
IUUC-Afu-008964	Aspergillus fumigatus	51.20	0.00e+00	841.00
IUUC-Ani-009379	Aspergillus nidulans	51.21	0.00e+00	844.00
IUUC-Ang-009756	Aspergillus niger	51.62	0.00e+00	847.00
IUUC-Aor-010174	Aspergillus oryzae	51.27	0.00e+00	836.00
IUUC-Ate-010302	Aspergillus terreus	45.63	0.00e+00	942.00
IUUC-Ame-011229	Astyanax mexicanus	77.47	0.00e+00	1305.00
IUUC-Bgr-012300	Blumeria graminis	44.82	0.00e+00	876.00
IUUC-Bta-012524	Bos taurus	79.87	0.00e+00	1698.00
IUUC-Bci-013781	Botrytis cinerea	51.64	0.00e+00	844.00
IUUC-Bdi-014549	Brachypodium distachyon	47.92	0.00e+00	979.00
IUUC-Bol-015967	Brassica oleracea	46.45	0.00e+00	928.00
IUUC-Bra-017823	Brassica rapa	46.65	0.00e+00	931.00
IUUC-Cel-018115	Caenorhabditis elegans	55.95	0.00e+00	917.00
IUUC-Cja-019107	Callithrix jacchus	76.62	0.00e+00	1631.00
IUUC-Cfa-020675	Canis familiaris	79.57	0.00e+00	1686.00
IUUC-Cpo-021813	Cavia porcellus	79.87	0.00e+00	1700.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	56.89	0.00e+00	896.00
IUUC-Csa-023523	Chlorocebus sabaeus	79.76	0.00e+00	1705.00
IUUC-Cho-024704	Choloepus hoffmanni	65.85	0.00e+00	1228.00
IUUC-Cin-025572	Ciona intestinalis	66.99	0.00e+00	1111.00
IUUC-Csv-025864	Ciona savignyi	65.41	0.00e+00	1040.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	53.03	0.00e+00	854.00
IUUC-Cne-027053	Cryptococcus neoformans	51.78	0.00e+00	859.00
IUUC-Cme-027222	Cyanidioschyzon merolae	35.71	1.00e-99	358.00
IUUC-Dre-027421	Danio rerio	73.39	0.00e+00	1572.00
IUUC-Dno-029303	Dasypus novemcinctus	79.85	0.00e+00	1703.00
IUUC-Dor-030290	Dipodomys ordii	64.85	0.00e+00	665.00
IUUC-Dse-031543	Dothistroma septosporum	44.66	0.00e+00	857.00
IUUC-Dme-031945	Drosophila melanogaster	64.64	0.00e+00	1038.00
IUUC-Ete-032873	Echinops telfairi	79.76	0.00e+00	1301.00
IUUC-Eca-033773	Equus caballus	80.15	0.00e+00	1703.00
IUUC-Eeu-034874	Erinaceus europaeus	69.09	0.00e+00	973.00
IUUC-Fca-035739	Felis catus	77.29	0.00e+00	1670.00
IUUC-Fal-037263	Ficedula albicollis	72.78	0.00e+00	1494.00
IUUC-Fox-037738	Fusarium oxysporum	47.41	0.00e+00	954.00
IUUC-Fso-038153	Fusarium solani	52.41	0.00e+00	853.00
IUUC-Gmo-039602	Gadus morhua	73.02	0.00e+00	1538.00
IUUC-Ggr-039931	Gaeumannomyces graminis	51.81	0.00e+00	852.00
IUUC-Gga-040590	Gallus gallus	79.69	0.00e+00	1700.00
IUUC-Gac-041318	Gasterosteus aculeatus	73.36	0.00e+00	1573.00
IUUC-Gma-043894	Glycine max	54.82	0.00e+00	887.00
IUUC-Ggo-045029	Gorilla gorilla	79.18	0.00e+00	1693.00
IUUC-Hsa-046078	Homo sapiens	78.83	0.00e+00	1692.00
IUUC-Hvu-047556	Hordeum vulgare	47.70	0.00e+00	976.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	75.40	0.00e+00	1068.00
IUUC-Kpa-049256	Komagataella pastoris	48.67	0.00e+00	780.00
IUUC-Lch-049706	Latimeria chalumnae	76.17	0.00e+00	1635.00
IUUC-Lpe-051553	Leersia perrieri	54.13	0.00e+00	877.00
IUUC-Loc-051867	Lepisosteus oculatus	66.16	0.00e+00	1068.00
IUUC-Lma-053138	Leptosphaeria maculans	51.72	0.00e+00	859.00
IUUC-Laf-053510	Loxodonta africana	81.16	0.00e+00	1713.00
IUUC-Mcc-055836	Macaca mulatta	80.92	0.00e+00	1695.00
IUUC-Meu-056238	Macropus eugenii	79.23	0.00e+00	964.00
IUUC-Mor-057172	Magnaporthe oryzae	47.14	0.00e+00	944.00
IUUC-Mpo-057300	Magnaporthe poae	51.69	0.00e+00	852.00
IUUC-Mtr-058248	Medicago truncatula	48.35	0.00e+00	975.00
IUUC-Mla-059019	Melampsora laricipopulina	53.36	0.00e+00	871.00
IUUC-Mga-059499	Meleagris gallopavo	79.63	0.00e+00	1695.00
IUUC-Mvi-060336	Microbotryum violaceum	53.05	0.00e+00	864.00
IUUC-Mmr-061102	Microcebus murinus	77.74	0.00e+00	1684.00
IUUC-Mdo-062594	Monodelphis domestica	80.89	0.00e+00	1714.00
IUUC-Mmu-063736	Mus musculus	79.40	0.00e+00	1688.00
IUUC-Mac-065272	Musa acuminata	47.06	0.00e+00	920.00
IUUC-Mpu-066701	Mustela putorius furo	79.58	0.00e+00	1690.00
IUUC-Mlu-067392	Myotis lucifugus	80.81	0.00e+00	1693.00
IUUC-Nfi-068270	Neosartorya fischeri	51.58	0.00e+00	842.00
IUUC-Ncr-068892	Neurospora crassa	51.75	0.00e+00	850.00
IUUC-Nle-069634	Nomascus leucogenys	86.50	0.00e+00	1144.00
IUUC-Opr-070952	Ochotona princeps	73.36	0.00e+00	995.00
IUUC-Ont-072488	Oreochromis niloticus	73.91	0.00e+00	1578.00
IUUC-Oan-073184	Ornithorhynchus anatinus	42.91	1.00e-64	239.00
IUUC-Ocu-074211	Oryctolagus cuniculus	80.15	0.00e+00	1703.00
IUUC-Oba-075761	Oryza barthii	54.13	0.00e+00	890.00
IUUC-Obr-076429	Oryza brachyantha	53.97	0.00e+00	889.00
IUUC-Ogl-077364	Oryza glaberrima	54.13	0.00e+00	890.00
IUUC-Ogu-078257	Oryza glumaepatula	54.43	0.00e+00	889.00
IUUC-Oin-079274	Oryza indica	54.01	0.00e+00	889.00
IUUC-Olo-080466	Oryza longistaminata	54.12	0.00e+00	879.00
IUUC-Ome-081993	Oryza meridionalis	57.67	0.00e+00	854.00
IUUC-Oni-082874	Oryza nivara	54.13	0.00e+00	889.00
IUUC-Opu-083697	Oryza punctata	54.13	0.00e+00	887.00
IUUC-Oru-084274	Oryza rufipogon	54.13	0.00e+00	890.00
IUUC-Osa-085565	Oryza sativa	54.13	0.00e+00	890.00
IUUC-Ola-086921	Oryzias latipes	73.24	0.00e+00	1560.00
IUUC-Olu-087639	Ostreococcus lucimarinus	49.68	0.00e+00	985.00
IUUC-Oga-087991	Otolemur garnettii	74.24	0.00e+00	1561.00
IUUC-Oar-089590	Ovis aries	79.87	0.00e+00	1698.00
IUUC-Ptr-090808	Pan troglodytes	78.92	0.00e+00	1694.00
IUUC-Pan-092475	Papio anubis	79.63	0.00e+00	1694.00
IUUC-Pno-094839	Phaeosphaeria nodorum	51.69	0.00e+00	809.00
IUUC-Ppa-095254	Physcomitrella patens	58.57	0.00e+00	947.00
IUUC-Pfo-097493	Poecilia formosa	74.19	0.00e+00	1580.00
IUUC-Pab-098497	Pongo abelii	79.76	0.00e+00	1704.00
IUUC-Pop-100086	Populus trichocarpa	56.08	0.00e+00	881.00
IUUC-Pca-100413	Procavia capensis	75.91	0.00e+00	811.00
IUUC-Ppe-101899	Prunus persica	54.70	0.00e+00	895.00
IUUC-Pva-102126	Pteropus vampyrus	75.09	0.00e+00	1580.00
IUUC-Pgr-103376	Puccinia graminis	48.63	0.00e+00	983.00
IUUC-Ptt-103978	Puccinia triticina	43.00	0.00e+00	777.00
IUUC-Pte-104126	Pyrenophora teres	51.77	0.00e+00	831.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	41.00	9.00e-134	471.00
IUUC-Rno-105428	Rattus norvegicus	79.69	0.00e+00	1694.00
IUUC-Sce-106464	Saccharomyces cerevisiae	39.82	0.00e+00	769.00
IUUC-Sha-107301	Sarcophilus harrisii	79.93	0.00e+00	1701.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	43.57	0.00e+00	838.00
IUUC-Spo-108217	Schizosaccharomyces pombe	45.14	0.00e+00	890.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	51.88	0.00e+00	845.00
IUUC-Smo-109458	Selaginella moellendorffii	57.26	0.00e+00	941.00
IUUC-Sit-109697	Setaria italica	53.74	0.00e+00	884.00
IUUC-Sly-111759	Solanum lycopersicum	48.28	0.00e+00	989.00
IUUC-Stu-112564	Solanum tuberosum	55.62	0.00e+00	909.00
IUUC-Sar-113313	Sorex araneus	63.90	0.00e+00	845.00
IUUC-Sbi-114388	Sorghum bicolor	54.33	0.00e+00	890.00
IUUC-Sre-115209	Sporisorium reilianum	52.11	0.00e+00	857.00
IUUC-Ssc-115933	Sus scrofa	79.87	0.00e+00	1700.00
IUUC-Tgu-117109	Taeniopygia guttata	65.46	3.00e-130	458.00
IUUC-Tru-117772	Takifugu rubripes	72.85	0.00e+00	1553.00
IUUC-Tsy-119105	Tarsius syrichta	67.76	0.00e+00	1402.00
IUUC-Tni-120556	Tetraodon nigroviridis	58.85	0.00e+00	1149.00
IUUC-Tca-121545	Theobroma cacao	55.69	0.00e+00	902.00
IUUC-Tre-121951	Trichoderma reesei	52.48	0.00e+00	848.00
IUUC-Tvi-122359	Trichoderma virens	47.45	0.00e+00	926.00
IUUC-Tae-123611	Triticum aestivum	54.25	0.00e+00	894.00
IUUC-Tur-126754	Triticum urartu	54.01	0.00e+00	894.00
IUUC-Tme-127170	Tuber melanosporum	47.47	0.00e+00	943.00
IUUC-Tbe-127882	Tupaia belangeri	72.92	0.00e+00	682.00
IUUC-Ttr-128217	Tursiops truncatus	76.74	0.00e+00	1618.00
IUUC-Uma-129337	Ustilago maydis	51.87	0.00e+00	854.00
IUUC-Vda-129828	Verticillium dahliae	51.69	0.00e+00	847.00
IUUC-Vpa-130537	Vicugna pacos	78.67	0.00e+00	1681.00
IUUC-Vvi-130958	Vitis vinifera	54.44	0.00e+00	885.00
IUUC-Xtr-132857	Xenopus tropicalis	78.12	0.00e+00	1652.00
IUUC-Xma-133138	Xiphophorus maculatus	74.10	0.00e+00	1581.00
IUUC-Yli-134399	Yarrowia lipolytica	46.42	0.00e+00	720.00
IUUC-Zma-135612	Zea mays	53.65	0.00e+00	877.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence