iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004982

UUCD1 version

UUC-AnC-00441

Ensembl Protein ID

ENSACAP00000015659.3

UniProt Accession

G1KRV4; G1KRV4_ANOCA

Protein Name

Uncharacterized protein

Gene Name

UBR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000015852.3	ENSACAT00000015974.3	ENSACAP00000015659.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.10e-08	35.4	1099	1203
E3 activity/N-recognin/N-domain	1.00e-32	112.1	222	298
E3 activity/N-recognin/UBR-box	1.00e-30	106.0	92	162

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf.............................................kdgplvlpCgHvfhadClqkw............. 29
           C++C+e+                                              ++g+++++CgHv+ha C+qk+             
   Q: 1099 CILCQEEQevklecaamvlsacvqkstaltqhmgkmlefsgdkidplfmnpdlSCGTHTGSCGHVMHAACWQKYfeaiqlnsrqrhh 1185
           7788444433333333333333332222222222223333333333333333356899*******************9****99999 PP
   S: 30   .pglknssskefrCPlCr 46
             +  +++++e +CPlC+
   Q: 1186 vEQVFDLENGEYLCPLCK 1203
           999999999999*****7 PP

E3 activity/N-recognin/N-domain

   S: 1    YylvLfNDEkHsyeqviyslqkAleleqkeakkfatiidkeGRravkaGdyavceeakkeilknseklaqipLkVev 77
           Yy+v+fNDE+Hsy++viyslq+ l +e+ ea++++t+idkeGR+avk G y vc+eak++i+k+s++++q  L+V+v
   Q: 222  YYCVVFNDEHHSYDHVIYSLQRTLGCELGEAQLYTTAIDKEGRKAVKKGPYIVCQEAKEDIKKHSSNVSQGALNVKV 298
           9*************************************************************************987 PP

E3 activity/N-recognin/UBR-box

   S: 1    slCgrvfkvgetiyeCrtCsvdetlvlCteCfakvvHkdHeyklkksggggfCdCGdteAwedgskCkkll 71
           +lCg+vfk get+y+Cr+C++d+t+vlC++Cf++++Hk+H+yk+++s+gggfCdCGdteAw++g++C +++
   Q: 92   QLCGKVFKGGETTYSCRECAIDPTCVLCMDCFQNSIHKNHRYKMHTSTGGGFCDCGDTEAWKTGPFCTNHE 162
           68******************************************************************996 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MADGGGGGGA AAAPAKPSEL SRWWDEKLDF YTAFLQHLAK VIPDIYSDEM DSMPEKEEEI 60
IQMTILYPLE WYLFGEDPDI CLEKLRQSST PQLCGKVFKG GETTYSCREC AIDPTCVLCM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGATTTC TGGGAGTTGT AGGCCAAAAC ACAGGTTGAG AACCACTGCT ATATAGCTTT 60
GAGCCACAGT GGCTGAAGTG GCGTCAGACT ACATTCATTC TACACCTGCA CCCTTACGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR003769--ClpS_core
IPR014719--Ribosomal_L7/12_C/ClpS-like
IPR011991--WHTH_DNA-bd_dom
IPR013083--Znf_RING/FYVE/PHD
IPR003126--Znf_UBR

PROSITE

PS51157--ZF_UBR

Pfam

PF02617--ClpS
PF02207--zf-UBR

SMART

SM00396--ZnF_UBR1

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000502--C:proteasome complex
GO:0000151--C:ubiquitin ligase complex
GO:0070728--F:leucine binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0071233--P:cellular response to leucine
GO:0032007--P:negative regulation of TOR signaling
GO:0071596--P:ubiquitin-dependent protein catabolic process via the N-end rule pathway

KEGG

acs:100558444

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001354	Ailuropoda melanoleuca	74.68	0.00e+00	2612.00
IUUC-Apl-004160	Anas platyrhynchos	77.85	0.00e+00	2734.00
IUUC-Acl-008055	Aspergillus clavatus	25.08	6.00e-39	157.00
IUUC-Ame-011231	Astyanax mexicanus	56.92	0.00e+00	1867.00
IUUC-Bgr-011999	Blumeria graminis	23.60	3.00e-49	191.00
IUUC-Bta-012347	Bos taurus	74.80	0.00e+00	2613.00
IUUC-Bci-013834	Botrytis cinerea	23.43	1.00e-49	192.00
IUUC-Cja-018911	Callithrix jacchus	73.27	0.00e+00	2550.00
IUUC-Cfa-020991	Canis familiaris	75.60	0.00e+00	2642.00
IUUC-Cpo-021448	Cavia porcellus	73.59	0.00e+00	2581.00
IUUC-Cre-022930	Chlamydomonas reinhardtii	46.15	2.10e-02	30.80
IUUC-Csa-024255	Chlorocebus sabaeus	75.26	0.00e+00	2149.00
IUUC-Cho-024550	Choloepus hoffmanni	58.34	0.00e+00	1910.00
IUUC-Dno-029427	Dasypus novemcinctus	74.24	0.00e+00	2545.00
IUUC-Dor-031073	Dipodomys ordii	64.63	0.00e+00	1115.00
IUUC-Ete-032318	Echinops telfairi	61.09	0.00e+00	992.00
IUUC-Eca-033348	Equus caballus	75.05	0.00e+00	2450.00
IUUC-Eeu-034664	Erinaceus europaeus	67.74	0.00e+00	2345.00
IUUC-Fca-035604	Felis catus	73.24	0.00e+00	1262.00
IUUC-Fal-037333	Ficedula albicollis	78.30	0.00e+00	2714.00
IUUC-Gmo-039363	Gadus morhua	54.70	0.00e+00	1589.00
IUUC-Gga-040486	Gallus gallus	76.77	0.00e+00	2647.00
IUUC-Gac-041985	Gasterosteus aculeatus	55.83	0.00e+00	1682.00
IUUC-Ggo-044704	Gorilla gorilla	69.52	0.00e+00	2017.00
IUUC-Hsa-046753	Homo sapiens	75.37	0.00e+00	2627.00
IUUC-Itr-048410	Ictidomys tridecemlineatus	75.32	0.00e+00	2616.00
IUUC-Lch-049904	Latimeria chalumnae	61.40	0.00e+00	2086.00
IUUC-Loc-052624	Lepisosteus oculatus	60.72	0.00e+00	2022.00
IUUC-Laf-053857	Loxodonta africana	73.99	0.00e+00	2576.00
IUUC-Mcc-054873	Macaca mulatta	75.37	0.00e+00	2597.00
IUUC-Meu-056858	Macropus eugenii	61.51	0.00e+00	934.00
IUUC-Mga-059917	Meleagris gallopavo	77.64	0.00e+00	2749.00
IUUC-Mmr-061128	Microcebus murinus	71.81	0.00e+00	2446.00
IUUC-Mdo-062306	Monodelphis domestica	75.12	0.00e+00	2585.00
IUUC-Mmu-063389	Mus musculus	74.63	0.00e+00	2607.00
IUUC-Mpu-065983	Mustela putorius furo	75.37	0.00e+00	2647.00
IUUC-Mlu-068013	Myotis lucifugus	72.70	0.00e+00	2536.00
IUUC-Nle-070031	Nomascus leucogenys	75.66	0.00e+00	2641.00
IUUC-Opr-070551	Ochotona princeps	59.26	0.00e+00	841.00
IUUC-Ont-072035	Oreochromis niloticus	57.11	0.00e+00	1929.00
IUUC-Ocu-074930	Oryctolagus cuniculus	71.97	0.00e+00	2496.00
IUUC-Osa-086106	Oryza sativa	43.00	2.00e-13	70.90
IUUC-Ola-086683	Oryzias latipes	56.59	0.00e+00	1870.00
IUUC-Oga-088017	Otolemur garnettii	72.45	0.00e+00	2504.00
IUUC-Oar-089557	Ovis aries	74.53	0.00e+00	2610.00
IUUC-Ptr-091366	Pan troglodytes	74.57	0.00e+00	2608.00
IUUC-Pan-092184	Papio anubis	75.37	0.00e+00	2597.00
IUUC-Psi-093720	Pelodiscus sinensis	79.42	0.00e+00	2721.00
IUUC-Pma-094152	Petromyzon marinus	38.83	2.00e-146	513.00
IUUC-Pfo-097124	Poecilia formosa	56.61	0.00e+00	1894.00
IUUC-Pab-098586	Pongo abelii	75.78	0.00e+00	2642.00
IUUC-Pop-099184	Populus trichocarpa	43.16	1.00e-13	70.90
IUUC-Pca-100673	Procavia capensis	68.37	0.00e+00	1370.00
IUUC-Pva-102724	Pteropus vampyrus	69.51	0.00e+00	2378.00
IUUC-Rno-105474	Rattus norvegicus	71.46	0.00e+00	1847.00
IUUC-Sce-106272	Saccharomyces cerevisiae	20.07	2.00e-23	105.00
IUUC-Sha-106993	Sarcophilus harrisii	75.00	0.00e+00	2646.00
IUUC-Spo-108183	Schizosaccharomyces pombe	24.31	6.00e-52	200.00
IUUC-Sar-113447	Sorex araneus	72.21	0.00e+00	1735.00
IUUC-Sre-115045	Sporisorium reilianum	25.43	2.00e-45	178.00
IUUC-Ssc-115768	Sus scrofa	72.11	0.00e+00	2333.00
IUUC-Tgu-116949	Taeniopygia guttata	73.52	0.00e+00	2494.00
IUUC-Tru-117782	Takifugu rubripes	55.36	0.00e+00	1883.00
IUUC-Tsy-119177	Tarsius syrichta	66.19	0.00e+00	1759.00
IUUC-Tni-120884	Tetraodon nigroviridis	51.57	0.00e+00	1702.00
IUUC-Tbe-128088	Tupaia belangeri	63.87	0.00e+00	962.00
IUUC-Ttr-129062	Tursiops truncatus	70.44	0.00e+00	2418.00
IUUC-Vpa-130578	Vicugna pacos	68.88	0.00e+00	2320.00
IUUC-Xtr-132244	Xenopus tropicalis	61.02	0.00e+00	2074.00
IUUC-Xma-134112	Xiphophorus maculatus	56.55	0.00e+00	1903.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence