iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ogl-077097

Ensembl Protein ID

ORGLA01G0096100.1

UniProt Accession

I1NM71; I1NM71_ORYGL

Protein Name

Presenilin

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ORGLA01G0096100	ORGLA01G0096100.1	ORGLA01G0096100.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/CUE	56.52	1.00e-22	104.00	IUUC-Cel-018553
UBD/Alpha-Helix/CUE	31.30	7.00e-26	115.00	IUUC-Dre-028689
UBD/Alpha-Helix/CUE	34.26	6.00e-28	123.00	IUUC-Hsa-046822

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Oryza glaberrima

Functional Description
(View)

Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.

Protein Sequence
(Fasta)

MDPAAGSPDP APAPGATTST AATVLDGLGA EVLAVMSPVS ICMALVVLLI SLLAPPSAPG 60
SAAAAAQPPP PVTAATLVYL ESPTDTPGQK LVGALLDAAV FVALVAVVTF VLVALYYYRC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATCCCG CCGCCGGCTC GCCGGATCCG GCGCCGGCGC CGGGGGCGAC CACCTCCACG 60
GCGGCGACCG TCCTCGACGG CCTCGGCGCG GAGGTGCTCG CGGTGATGTC GCCGGTCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0333--Golgi apparatus
KW-0378--Hydrolase
KW-0472--Membrane
KW-0914--Notch signaling pathway
KW-0645--Protease
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001108--Peptidase_A22A
IPR006639--Preselin/SPP

Pfam

PF01080--Presenilin

PRINTS

PR01072--PRESENILIN

SMART

SM00730--PSN

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0005798--C:Golgi-associated vesicle
GO:0016021--C:integral component of membrane
GO:0004190--F:aspartic-type endopeptidase activity
GO:0007219--P:Notch signaling pathway
GO:0016485--P:protein processing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000686	Aegilops tauschii	75.80	3.00e-134	471.00
IUUC-Aml-001648	Ailuropoda melanoleuca	33.92	3.00e-33	134.00
IUUC-Atr-003039	Amborella trichopoda	52.31	9.00e-107	379.00
IUUC-Apl-003727	Anas platyrhynchos	30.58	4.00e-33	134.00
IUUC-Aca-004582	Anolis carolinensis	31.32	1.00e-33	136.00
IUUC-Aly-005455	Arabidopsis lyrata	49.68	4.00e-99	353.00
IUUC-Ath-006730	Arabidopsis thaliana	49.36	1.00e-98	352.00
IUUC-Ame-011500	Astyanax mexicanus	29.62	1.00e-30	126.00
IUUC-Bta-013026	Bos taurus	30.20	4.00e-32	131.00
IUUC-Bdi-014196	Brachypodium distachyon	79.04	1.00e-155	542.00
IUUC-Bol-015841	Brassica oleracea	51.60	2.00e-94	338.00
IUUC-Bra-017580	Brassica rapa	52.05	2.00e-82	298.00
IUUC-Cel-018553	Caenorhabditis elegans	30.63	3.00e-41	162.00
IUUC-Cja-018824	Callithrix jacchus	31.25	2.00e-25	109.00
IUUC-Cfa-020074	Canis familiaris	31.54	4.00e-35	141.00
IUUC-Cpo-022237	Cavia porcellus	32.21	8.00e-34	137.00
IUUC-Cre-022747	Chlamydomonas reinhardtii	40.80	4.00e-42	165.00
IUUC-Csa-023537	Chlorocebus sabaeus	32.89	4.00e-35	141.00
IUUC-Cho-024735	Choloepus hoffmanni	34.56	2.00e-29	122.00
IUUC-Cin-025780	Ciona intestinalis	31.10	2.00e-38	152.00
IUUC-Csv-025967	Ciona savignyi	31.70	6.00e-23	100.00
IUUC-Dre-028689	Danio rerio	31.33	3.00e-30	125.00
IUUC-Dno-029758	Dasypus novemcinctus	32.66	2.00e-35	142.00
IUUC-Dor-030609	Dipodomys ordii	55.56	6.00e-19	87.80
IUUC-Dme-031929	Drosophila melanogaster	33.63	3.00e-25	108.00
IUUC-Ete-032487	Echinops telfairi	35.97	1.00e-14	73.60
IUUC-Eca-034387	Equus caballus	32.00	4.00e-26	111.00
IUUC-Eeu-035134	Erinaceus europaeus	34.56	9.00e-32	129.00
IUUC-Fca-036243	Felis catus	31.54	2.00e-34	139.00
IUUC-Fal-036600	Ficedula albicollis	30.65	2.00e-33	135.00
IUUC-Gmo-038550	Gadus morhua	32.00	5.00e-26	111.00
IUUC-Gga-040993	Gallus gallus	31.10	2.00e-35	142.00
IUUC-Gac-042511	Gasterosteus aculeatus	32.06	5.00e-34	137.00
IUUC-Gma-043822	Glycine max	59.75	5.00e-43	167.00
IUUC-Ggo-045338	Gorilla gorilla	32.60	1.00e-26	113.00
IUUC-Hsa-046822	Homo sapiens	32.89	3.00e-35	141.00
IUUC-Hvu-047141	Hordeum vulgare	76.92	1.00e-143	501.00
IUUC-Itr-048420	Ictidomys tridecemlineatus	33.42	1.00e-33	135.00
IUUC-Lch-049638	Latimeria chalumnae	30.40	3.00e-25	108.00
IUUC-Lpe-051132	Leersia perrieri	89.29	5.00e-167	579.00
IUUC-Loc-052427	Lepisosteus oculatus	29.75	3.00e-35	142.00
IUUC-Laf-053979	Loxodonta africana	31.39	3.00e-31	128.00
IUUC-Mcc-055682	Macaca mulatta	32.89	3.00e-35	141.00
IUUC-Meu-056004	Macropus eugenii	27.36	3.00e-21	95.10
IUUC-Mtr-058392	Medicago truncatula	51.18	5.00e-99	353.00
IUUC-Mga-059466	Meleagris gallopavo	31.39	5.00e-35	140.00
IUUC-Mmr-060890	Microcebus murinus	31.72	8.00e-26	110.00
IUUC-Mdo-062122	Monodelphis domestica	31.99	1.00e-33	136.00
IUUC-Mmu-063823	Mus musculus	31.97	1.00e-26	113.00
IUUC-Mac-064858	Musa acuminata	67.65	1.00e-45	175.00
IUUC-Mpu-065927	Mustela putorius furo	31.77	1.00e-35	142.00
IUUC-Mlu-067079	Myotis lucifugus	31.77	5.00e-38	150.00
IUUC-Nle-070180	Nomascus leucogenys	32.89	3.00e-35	141.00
IUUC-Opr-070344	Ochotona princeps	31.11	1.00e-23	103.00
IUUC-Ont-071846	Oreochromis niloticus	31.03	3.00e-31	129.00
IUUC-Oan-072783	Ornithorhynchus anatinus	33.74	2.00e-28	119.00
IUUC-Ocu-074527	Oryctolagus cuniculus	31.32	2.00e-34	139.00
IUUC-Oba-075256	Oryza barthii	100.00	2.00e-168	584.00
IUUC-Obr-076302	Oryza brachyantha	88.22	2.00e-167	581.00
IUUC-Ogu-078570	Oryza glumaepatula	99.75	2.00e-180	624.00
IUUC-Oin-079244	Oryza indica	99.56	0.00e+00	647.00
IUUC-Olo-080484	Oryza longistaminata	97.93	2.00e-130	456.00
IUUC-Ome-081814	Oryza meridionalis	94.81	0.00e+00	650.00
IUUC-Oni-082057	Oryza nivara	99.50	6.00e-180	622.00
IUUC-Opu-084176	Oryza punctata	96.25	1.00e-178	618.00
IUUC-Oru-084618	Oryza rufipogon	99.75	1.00e-180	625.00
IUUC-Osa-085602	Oryza sativa	99.50	0.00e+00	629.00
IUUC-Ola-086707	Oryzias latipes	31.11	3.00e-26	111.00
IUUC-Olu-087811	Ostreococcus lucimarinus	41.33	7.00e-39	153.00
IUUC-Oga-088560	Otolemur garnettii	31.72	5.00e-26	111.00
IUUC-Oar-090348	Ovis aries	31.10	9.00e-37	147.00
IUUC-Ptr-091060	Pan troglodytes	32.89	3.00e-35	141.00
IUUC-Pan-091742	Papio anubis	32.60	9.00e-27	113.00
IUUC-Psi-093505	Pelodiscus sinensis	31.32	1.00e-34	139.00
IUUC-Pma-094612	Petromyzon marinus	28.26	1.00e-21	97.10
IUUC-Ppa-095431	Physcomitrella patens	43.15	5.00e-90	323.00
IUUC-Pfo-097396	Poecilia formosa	30.60	4.00e-37	148.00
IUUC-Pab-098591	Pongo abelii	32.89	4.00e-35	141.00
IUUC-Pop-099661	Populus trichocarpa	45.83	2.00e-81	295.00
IUUC-Pca-101029	Procavia capensis	31.10	1.00e-29	123.00
IUUC-Ppe-101495	Prunus persica	51.75	7.00e-107	379.00
IUUC-Pva-102934	Pteropus vampyrus	30.22	3.00e-24	105.00
IUUC-Rno-106052	Rattus norvegicus	31.72	5.00e-26	111.00
IUUC-Sha-107045	Sarcophilus harrisii	31.10	3.00e-34	138.00
IUUC-Smo-109325	Selaginella moellendorffii	42.45	3.00e-60	224.00
IUUC-Sit-110624	Setaria italica	80.69	6.00e-148	516.00
IUUC-Sly-110865	Solanum lycopersicum	85.92	1.00e-32	130.00
IUUC-Stu-112433	Solanum tuberosum	50.86	4.00e-98	350.00
IUUC-Sar-113169	Sorex araneus	40.19	5.00e-19	88.20
IUUC-Sbi-114305	Sorghum bicolor	79.87	3.00e-151	527.00
IUUC-Ssc-115766	Sus scrofa	31.46	4.00e-33	134.00
IUUC-Tgu-116469	Taeniopygia guttata	31.84	6.00e-30	123.00
IUUC-Tru-117732	Takifugu rubripes	30.43	1.00e-32	133.00
IUUC-Tsy-119624	Tarsius syrichta	30.40	4.00e-21	94.70
IUUC-Tni-119852	Tetraodon nigroviridis	28.19	5.00e-20	91.30
IUUC-Tca-121865	Theobroma cacao	55.29	3.00e-101	360.00
IUUC-Tae-123984	Triticum aestivum	76.04	4.00e-140	490.00
IUUC-Tur-126237	Triticum urartu	77.81	4.00e-123	433.00
IUUC-Tbe-127632	Tupaia belangeri	32.60	1.00e-26	113.00
IUUC-Ttr-128793	Tursiops truncatus	33.24	1.00e-31	130.00
IUUC-Vpa-130625	Vicugna pacos	39.05	3.00e-18	85.50
IUUC-Vvi-131312	Vitis vinifera	53.04	2.00e-97	348.00
IUUC-Xtr-132756	Xenopus tropicalis	29.84	4.00e-34	138.00
IUUC-Xma-133377	Xiphophorus maculatus	29.50	1.00e-35	142.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence