iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037074

Ensembl Protein ID

ENSFALP00000011878.1

UniProt Accession

U3KA24; U3KA24_FICAL

Genbank Protein ID

ENSFALP00000011878

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01020862

Gene Name

SH3RF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000011380.1	ENSFALT00000011927.1	ENSFALP00000011878.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.00e-08	33.7	12	53
UBD/SH3	1.10e-47	159.5	441	495

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cle+++   +vlpC+H+f++ Cl  +     ss++e rCP Cr
   Q: 12   CPVCLERLDASAKVLPCQHTFCKRCLLGI----VSSRNELRCPECR 53
           **********9**************9777....89**********8 PP

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
             ++y+y++ ++deL+l+kG++ lv  + +   gW kg++  + k G+fP n+++ +
   Q: 441  YVAIYPYTPRKEDELELRKGEMFLVF-ERC-QDGWFKGTSMHTSKIGVFPGNYMAPV 495
           679**********************9.555.569*******************9987 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MDESALLDLL ECPVCLERLD ASAKVLPCQH TFCKRCLLGI VSSRNELRCP ECRTLVDCGV 60
DELPSNILLV RLLDGIKQRP RKPGGTAGTN ALRVPINTVA NCGSKDLQSS QVGQQQRVQA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG 60
GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGCGCCGCCG CCGCGTCCGC CCGCCCGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001452--SH3_domain
IPR028502--SH3RF1
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00018--SH3_1
PF14604--SH3_9
PF00097--zf-C3HC4

PRINTS

PR00452--SH3DOMAIN

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0046328--P:regulation of JNK cascade

KEGG

fab:101814606

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001528	Ailuropoda melanoleuca	78.14	0.00e+00	1184.00
IUUC-Apl-003961	Anas platyrhynchos	93.59	0.00e+00	1419.00
IUUC-Aca-004386	Anolis carolinensis	83.05	0.00e+00	1276.00
IUUC-Ago-007765	Ashbya gossypii	41.38	5.00e-11	62.00
IUUC-Ame-010659	Astyanax mexicanus	60.66	0.00e+00	905.00
IUUC-Bta-012563	Bos taurus	69.30	0.00e+00	762.00
IUUC-Cja-019730	Callithrix jacchus	76.97	0.00e+00	1162.00
IUUC-Cfa-020992	Canis familiaris	78.00	0.00e+00	1201.00
IUUC-Cpo-021304	Cavia porcellus	78.29	0.00e+00	1222.00
IUUC-Csa-023925	Chlorocebus sabaeus	77.93	0.00e+00	1174.00
IUUC-Cho-024630	Choloepus hoffmanni	71.76	0.00e+00	771.00
IUUC-Cin-025274	Ciona intestinalis	49.03	3.00e-73	268.00
IUUC-Csv-026136	Ciona savignyi	44.10	1.00e-75	276.00
IUUC-Cme-027278	Cyanidioschyzon merolae	42.55	3.00e-08	53.90
IUUC-Dre-028290	Danio rerio	65.44	0.00e+00	791.00
IUUC-Dno-029083	Dasypus novemcinctus	82.01	0.00e+00	946.00
IUUC-Dor-030388	Dipodomys ordii	85.96	6.00e-176	610.00
IUUC-Dme-032207	Drosophila melanogaster	44.57	1.00e-66	247.00
IUUC-Ete-032809	Echinops telfairi	69.97	0.00e+00	740.00
IUUC-Eca-034185	Equus caballus	78.20	0.00e+00	1003.00
IUUC-Eeu-034816	Erinaceus europaeus	68.88	0.00e+00	991.00
IUUC-Fca-036439	Felis catus	76.68	0.00e+00	1209.00
IUUC-Gmo-039443	Gadus morhua	60.86	1.00e-121	430.00
IUUC-Gga-040749	Gallus gallus	89.92	0.00e+00	1305.00
IUUC-Gac-041420	Gasterosteus aculeatus	63.30	0.00e+00	683.00
IUUC-Ggo-045215	Gorilla gorilla	77.23	0.00e+00	1201.00
IUUC-Hsa-046315	Homo sapiens	77.03	0.00e+00	1195.00
IUUC-Itr-048265	Ictidomys tridecemlineatus	71.07	7.00e-122	429.00
IUUC-Kpa-049247	Komagataella pastoris	41.82	5.00e-10	58.50
IUUC-Lch-049453	Latimeria chalumnae	74.60	0.00e+00	968.00
IUUC-Laf-053651	Loxodonta africana	78.33	0.00e+00	1161.00
IUUC-Mcc-054688	Macaca mulatta	77.98	0.00e+00	1195.00
IUUC-Meu-056291	Macropus eugenii	73.26	0.00e+00	766.00
IUUC-Mpo-057322	Magnaporthe poae	41.38	7.00e-12	66.60
IUUC-Mga-059944	Meleagris gallopavo	90.61	0.00e+00	1370.00
IUUC-Mmr-061553	Microcebus murinus	75.96	0.00e+00	1117.00
IUUC-Mdo-062313	Monodelphis domestica	76.84	0.00e+00	1172.00
IUUC-Mmu-063516	Mus musculus	77.80	0.00e+00	1222.00
IUUC-Mpu-066064	Mustela putorius furo	77.39	0.00e+00	1183.00
IUUC-Mlu-067312	Myotis lucifugus	74.67	0.00e+00	1122.00
IUUC-Nle-069035	Nomascus leucogenys	77.23	0.00e+00	1203.00
IUUC-Opr-070690	Ochotona princeps	71.93	1.00e-159	556.00
IUUC-Ont-071484	Oreochromis niloticus	65.50	0.00e+00	759.00
IUUC-Oan-073305	Ornithorhynchus anatinus	80.55	0.00e+00	1227.00
IUUC-Ocu-074936	Oryctolagus cuniculus	76.79	0.00e+00	1177.00
IUUC-Ola-086675	Oryzias latipes	63.37	0.00e+00	641.00
IUUC-Oga-087933	Otolemur garnettii	72.82	0.00e+00	925.00
IUUC-Oar-090408	Ovis aries	68.36	0.00e+00	736.00
IUUC-Ptr-090865	Pan troglodytes	77.14	0.00e+00	1201.00
IUUC-Pan-092362	Papio anubis	77.93	0.00e+00	1173.00
IUUC-Psi-093876	Pelodiscus sinensis	85.16	0.00e+00	1291.00
IUUC-Pfo-097116	Poecilia formosa	63.92	0.00e+00	766.00
IUUC-Pab-098127	Pongo abelii	77.14	0.00e+00	1201.00
IUUC-Pca-100485	Procavia capensis	80.23	0.00e+00	907.00
IUUC-Pva-102661	Pteropus vampyrus	75.48	0.00e+00	1137.00
IUUC-Rno-105728	Rattus norvegicus	77.43	0.00e+00	1198.00
IUUC-Sce-106404	Saccharomyces cerevisiae	46.43	1.00e-11	64.30
IUUC-Sha-106515	Sarcophilus harrisii	85.01	0.00e+00	875.00
IUUC-Sar-113161	Sorex araneus	72.52	0.00e+00	1028.00
IUUC-Ssc-115314	Sus scrofa	71.28	0.00e+00	1006.00
IUUC-Tgu-117012	Taeniopygia guttata	96.45	0.00e+00	1455.00
IUUC-Tru-118467	Takifugu rubripes	63.47	3.00e-171	595.00
IUUC-Tsy-119566	Tarsius syrichta	77.75	4.00e-165	575.00
IUUC-Tni-120830	Tetraodon nigroviridis	57.39	1.00e-180	626.00
IUUC-Tbe-128070	Tupaia belangeri	79.28	0.00e+00	816.00
IUUC-Ttr-128161	Tursiops truncatus	87.45	6.00e-128	451.00
IUUC-Vpa-130075	Vicugna pacos	64.75	5.00e-49	188.00
IUUC-Xtr-132628	Xenopus tropicalis	72.42	0.00e+00	1093.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence